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1 ostate cancer mortality) and minimize costs (overtreatment).
2 ates of re-excision, radical resections, and overtreatment.
3 native therapy or who may be spared possible overtreatment.
4 gement and ultimately increasing the risk of overtreatment.
5 ent infections while simultaneously limiting overtreatment.
6 e effects, and the risk of overdiagnosis and overtreatment.
7 has led to concerns about overdiagnosis and overtreatment.
8 y minimizing the inconveniences and costs of overtreatment.
9 d by screening, leading to overdiagnosis and overtreatment.
10 ncer has raised concerns about potential for overtreatment.
11 overdiagnosis and, if unrecognised, possible overtreatment.
12 ve malaria treatment without increasing NMFI overtreatment.
13 tion about CPM is needed to reduce potential overtreatment.
14 t outputs, but may significantly reduce NMFI overtreatment.
15 with moderate-dose statins while minimizing overtreatment.
16 carcinoma is not accurate enough to prevent overtreatment.
17 come symptomatic (overdiagnosis), leading to overtreatment.
18 identify indolent tumors are needed to avoid overtreatment.
19 apy decisions to improve outcomes and reduce overtreatment.
20 tantial potential risk for overdiagnosis and overtreatment.
21 ears to reduce the risk of PCSM with minimal overtreatment.
22 lives, there are growing concerns regarding overtreatment.
23 lacing the public at risk of overtesting and overtreatment.
24 d with prostate cancer screening, other than overtreatment?
26 erplasia include avoidance of glucocorticoid overtreatment and control of sex hormone imbalances.
27 of (18)F-FET PET has the potential to avoid overtreatment and corresponding costs, as well as unnece
28 ions have motivated lingering concerns about overtreatment and failure to involve women in treatment
30 decision making is fundamental to preventing overtreatment and promoting high-value, individualized p
32 ble therapy for individuals and avoidance of overtreatment and undertreatment of patients with conven
33 me INSS stage 1 patients (1) are at risk for overtreatment, and (2) have poor-prognostic biologic fin
34 to individualize glycemic goals and prevent overtreatment, and can serve as a template for applying
37 and indirect evidence that overdiagnosis and overtreatment are likely to be substantial with populati
38 o a 35% decrease (95% UI:31.2-39.8%) in NMFI overtreatment, but also a 19.5% reduction (95% UI:11-27.
39 n important option to reduce prostate cancer overtreatment, but it remains underutilized in many coun
40 nagement would have hypothetically decreased overtreatment by 94%, eliminating a median of 44 overtre
41 surgeon-led initiatives to address potential overtreatment can reduce the burden of surgical manageme
42 le range, 43-47) per patient and 2,169 total overtreatment days (95% confidence interval, 1,938-2,400
43 treatment by 94%, eliminating a median of 44 overtreatment days (interquartile range, 43-47) per pati
44 g the new model to indicate aRT might reduce overtreatment, decrease unnecessary adverse effects, and
45 rtality; and harms, including overdiagnosis, overtreatment, diagnostic procedure-related harms, fear,
46 herapy and to monitor their response so that overtreatment does not completely abrogate host defense
47 nt controversies surrounding prostate cancer overtreatment emphasize the critical need to delineate t
53 rategy could help to avoid overdiagnosis and overtreatment in patients with Barrett's oesophagus.
54 quality of care, has the potential to halve overtreatment in public and mission health facilities in
58 nefit from neo-adjuvant therapy and to avoid overtreatment in those patients who can proceed directly
66 tifying children with malaria, and that much overtreatment of children without parasitaemia could be
67 may provide an opportunity to further reduce overtreatment of disease that is unlikely to progress to
68 Recent recognition of the overdiagnosis and overtreatment of ductal carcinoma in situ (DCIS) detecte
69 e most adequate treatment, thus avoiding the overtreatment of frail patients and the undertreatment o
73 prostate cancer (PC) are suboptimal, causing overtreatment of indolent PC and risk of delayed treatme
74 to guide clinical decision-making and avoid overtreatment of indolent PC and undertreatment of aggre
76 eatment selection, but the data suggest both overtreatment of low-risk disease and undertreatment of
77 stratification are urgently needed to avoid overtreatment of low-risk patients and to prioritize alt
79 nsequences associated with overdiagnosis and overtreatment of Lyme disease, although previously recog
80 as been proposed as an approach for reducing overtreatment of malaria in the current era of widesprea
81 according to an algorithm designed to avoid overtreatment of mild disease and to accelerate treatmen
82 es treated with ACT, but also an increase in overtreatment of NMFI, with 70% NMFI cases (95% UI:56.4-
83 s causing a high degree of overdiagnosis and overtreatment of otherwise clinically insignificant case
87 screening results to avoid misdiagnosis and overtreatment of persons with isolated clinic hypertensi
88 ecific antigen screening has led to enormous overtreatment of prostate cancer because of the inabilit
95 atment intensity over time in order to avoid overtreatment or undertreatment, and the use of supporti
97 erformance at finding infections, minimizing overtreatment, reducing clinical case counts, and interr
99 ment, reducing pCRM involvement and avoiding overtreatment through selective preoperative therapy and
100 f all potential organisms, carrying risks of overtreatment, toxicity, and selection of multidrug-resi
101 ert Ultra will likely result in considerable overtreatment unless the possibility of higher specifici
102 l or low-grade pathology when calculation of overtreatment was restricted to patients diagnosed with
103 as lower (with a possibility of no increased overtreatment) when using specificity data only from low
104 persistent high rates of mastectomy suggest overtreatment, whereas lower than expected rates of radi
105 te balance between high cancer cure rate and overtreatment, which could potentially lead to unnecessa
107 only a treat-to-target approach may motivate overtreatment with high-dose statins, potentially leadin
109 , presumptive treatment leads to substantial overtreatment without additional morbidity reduction und
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