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1 ostate cancer mortality) and minimize costs (overtreatment).
2 ates of re-excision, radical resections, and overtreatment.
3 native therapy or who may be spared possible overtreatment.
4 gement and ultimately increasing the risk of overtreatment.
5 ent infections while simultaneously limiting overtreatment.
6 e effects, and the risk of overdiagnosis and overtreatment.
7  has led to concerns about overdiagnosis and overtreatment.
8 y minimizing the inconveniences and costs of overtreatment.
9 d by screening, leading to overdiagnosis and overtreatment.
10 ncer has raised concerns about potential for overtreatment.
11 overdiagnosis and, if unrecognised, possible overtreatment.
12 ve malaria treatment without increasing NMFI overtreatment.
13 tion about CPM is needed to reduce potential overtreatment.
14 t outputs, but may significantly reduce NMFI overtreatment.
15  with moderate-dose statins while minimizing overtreatment.
16  carcinoma is not accurate enough to prevent overtreatment.
17 come symptomatic (overdiagnosis), leading to overtreatment.
18 identify indolent tumors are needed to avoid overtreatment.
19 apy decisions to improve outcomes and reduce overtreatment.
20 tantial potential risk for overdiagnosis and overtreatment.
21 ears to reduce the risk of PCSM with minimal overtreatment.
22  lives, there are growing concerns regarding overtreatment.
23 lacing the public at risk of overtesting and overtreatment.
24 d with prostate cancer screening, other than overtreatment?
25 se is of utmost significance, as it prevents overtreatment and adverse effects in patients.
26 erplasia include avoidance of glucocorticoid overtreatment and control of sex hormone imbalances.
27  of (18)F-FET PET has the potential to avoid overtreatment and corresponding costs, as well as unnece
28 ions have motivated lingering concerns about overtreatment and failure to involve women in treatment
29 losis treatment, which indicates substantial overtreatment and limited undertreatment.
30 decision making is fundamental to preventing overtreatment and promoting high-value, individualized p
31 s an appealing strategy for the reduction of overtreatment and secondary adverse effects.
32 ble therapy for individuals and avoidance of overtreatment and undertreatment of patients with conven
33 me INSS stage 1 patients (1) are at risk for overtreatment, and (2) have poor-prognostic biologic fin
34  to individualize glycemic goals and prevent overtreatment, and can serve as a template for applying
35 eutical marketing can lead to overdiagnosis, overtreatment, and overuse of medications.
36 to identify factors predictive of adherence, overtreatment, and undertreatment.
37 and indirect evidence that overdiagnosis and overtreatment are likely to be substantial with populati
38 o a 35% decrease (95% UI:31.2-39.8%) in NMFI overtreatment, but also a 19.5% reduction (95% UI:11-27.
39 n important option to reduce prostate cancer overtreatment, but it remains underutilized in many coun
40 nagement would have hypothetically decreased overtreatment by 94%, eliminating a median of 44 overtre
41 surgeon-led initiatives to address potential overtreatment can reduce the burden of surgical manageme
42 le range, 43-47) per patient and 2,169 total overtreatment days (95% confidence interval, 1,938-2,400
43 treatment by 94%, eliminating a median of 44 overtreatment days (interquartile range, 43-47) per pati
44 g the new model to indicate aRT might reduce overtreatment, decrease unnecessary adverse effects, and
45 rtality; and harms, including overdiagnosis, overtreatment, diagnostic procedure-related harms, fear,
46 herapy and to monitor their response so that overtreatment does not completely abrogate host defense
47 nt controversies surrounding prostate cancer overtreatment emphasize the critical need to delineate t
48               In just 6 categories of waste--overtreatment, failures of care coordination, failures i
49                         We examined possible overtreatment for patients >/=18 years of age by examini
50  to therapies that would otherwise result in overtreatment for some patients.
51 rue disease, overtesting, overdiagnosis, and overtreatment have become common.
52 my or radiation therapy has been shown to be overtreatment in 30% of patients.
53 rategy could help to avoid overdiagnosis and overtreatment in patients with Barrett's oesophagus.
54  quality of care, has the potential to halve overtreatment in public and mission health facilities in
55                             The high rate of overtreatment in the population studied carries both fin
56                                     However, overtreatment in the see-and-treat strategy has been rep
57                                     To limit overtreatment in these cases, minimally invasive limited
58 nefit from neo-adjuvant therapy and to avoid overtreatment in those patients who can proceed directly
59         AS represents a strategy to mitigate overtreatment in young patients with low-risk PCa in the
60                                              Overtreatment, in an attempt to reduce symptoms, can be
61                            Overdetection and overtreatment is common in many areas of modern medicine
62                                              Overtreatment is pervasive in medicine and leads to pote
63                                              Overtreatment may be a growing problem, especially among
64                                     Range of overtreatment narrowed to 4.0-23.5% for those with norma
65           On the basis of concerns regarding overtreatment of biologically indolent cancers, focal ab
66 tifying children with malaria, and that much overtreatment of children without parasitaemia could be
67 may provide an opportunity to further reduce overtreatment of disease that is unlikely to progress to
68  Recent recognition of the overdiagnosis and overtreatment of ductal carcinoma in situ (DCIS) detecte
69 e most adequate treatment, thus avoiding the overtreatment of frail patients and the undertreatment o
70                                              Overtreatment of heparin-induced thrombocytopenia in the
71                                              Overtreatment of indolent disease also results in signif
72 ce early detection of aggressive disease and overtreatment of indolent disease.
73 prostate cancer (PC) are suboptimal, causing overtreatment of indolent PC and risk of delayed treatme
74  to guide clinical decision-making and avoid overtreatment of indolent PC and undertreatment of aggre
75                            Overdiagnosis and overtreatment of indolent prostate cancer (PCA) is a ser
76 eatment selection, but the data suggest both overtreatment of low-risk disease and undertreatment of
77  stratification are urgently needed to avoid overtreatment of low-risk patients and to prioritize alt
78                            Overdiagnosis and overtreatment of Lyme disease are associated with inappr
79 nsequences associated with overdiagnosis and overtreatment of Lyme disease, although previously recog
80 as been proposed as an approach for reducing overtreatment of malaria in the current era of widesprea
81  according to an algorithm designed to avoid overtreatment of mild disease and to accelerate treatmen
82 es treated with ACT, but also an increase in overtreatment of NMFI, with 70% NMFI cases (95% UI:56.4-
83 s causing a high degree of overdiagnosis and overtreatment of otherwise clinically insignificant case
84 t because of high rates of overdiagnosis and overtreatment of otherwise indolent tumors.
85 ing a therapeutic algorithm may lead to less overtreatment of patients and cost savings.
86 of a time frame for reevaluation lead to the overtreatment of patients?
87  screening results to avoid misdiagnosis and overtreatment of persons with isolated clinic hypertensi
88 ecific antigen screening has led to enormous overtreatment of prostate cancer because of the inabilit
89  causes long-term toxicity and may represent overtreatment of some patients.
90 -effectiveness and data addressing potential overtreatment of suspicious skin lesions.
91 ancer that has resulted in overdiagnosis and overtreatment of the disease.
92 improved survival, thereby avoiding systemic overtreatment of these patients.
93  urgently needed to reduce overdiagnosis and overtreatment of this common disease.
94                            At the same time, overtreatment of uninfected individuals increases the ri
95 atment intensity over time in order to avoid overtreatment or undertreatment, and the use of supporti
96 DL <100 mg/dL) had higher rates of potential overtreatment (P<0.001).
97 erformance at finding infections, minimizing overtreatment, reducing clinical case counts, and interr
98                    To address this potential overtreatment, sentinel lymph node (SLN) biopsy is curre
99 ment, reducing pCRM involvement and avoiding overtreatment through selective preoperative therapy and
100 f all potential organisms, carrying risks of overtreatment, toxicity, and selection of multidrug-resi
101 ert Ultra will likely result in considerable overtreatment unless the possibility of higher specifici
102 l or low-grade pathology when calculation of overtreatment was restricted to patients diagnosed with
103 as lower (with a possibility of no increased overtreatment) when using specificity data only from low
104  persistent high rates of mastectomy suggest overtreatment, whereas lower than expected rates of radi
105 te balance between high cancer cure rate and overtreatment, which could potentially lead to unnecessa
106                                        Thus, overtreatment with antibiotics is widely prevalent, but
107 only a treat-to-target approach may motivate overtreatment with high-dose statins, potentially leadin
108                    These trends suggest that overtreatment with multiple inotropes contributes to the
109 , presumptive treatment leads to substantial overtreatment without additional morbidity reduction und

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