ライフサイエンスコーパス: overwhelming

1 ories of individuals in need too emotionally overwhelming.

2 or the remains being those of Richard III is overwhelming.

3 g "preparedness for what," the task can seem overwhelming.

4 size and hectic pace of these events can be overwhelming.

5 However, the resulting deluge of data can be overwhelming.

6 we record the first example of a viral bloom overwhelming a CRISPR system.

7 proposed for addressing the challenge of the overwhelming abundance of genomic sequence and other bio

8 However, overwhelming activation and accumulation of neutrophils

9 One patient died from an overwhelming adenoviral infection before reconstitution

10 ral results presented here failed to show an overwhelming advantage for number problems.

11 Owing to the overwhelming advantage in energy density, lithium-sulfur

12 tA or equivalent mutations that conferred an overwhelming advantage.

13 ethylated CpGs at other gene regions, and by overwhelming age-related methylation in CpG islands and

14 arely a new research area has gotten such an overwhelming amount of attention as have microRNAs.

15 pled algorithmic approaches to deal with the overwhelming amount of data generated by modern mass spe

16 For the overwhelming amount of data produced in this study, we d

17 r technological solutions able to manage the overwhelming amount of high throughput genomic data need

18 f pathogen transcripts is complicated by the overwhelming amount of host RNA isolated from an infecte

19 Sensory environments often contain an overwhelming amount of information, with both relevant a

20 ing machines, these must be selected from an overwhelming amount of raw data.

21 es displayed by humans in making sense of an overwhelming amount of sensory information cannot be exp

22 s for a target antibody in the context of an overwhelming amount of unrelated immunoglobins present i

23 mponents of the immune system as well as the overwhelming amounts of data can make it difficult to in

24 The presence of overwhelming amounts of information in our big-data era

25 Our brains operate on overwhelming amounts of information, and thus their effi

26 n in such a capricious environment can prove overwhelming and compromise one's ability to effectively

27 ice with HOXA10 gene disruption exhibited an overwhelming and fatal emergency granulopoiesis response

28 synthetic methodology toward heterocycles is overwhelming, and catalysis, in particular, as one of th

29 t array of choices available to consumers is overwhelming, and most patients would like their physici

30 The literature on this subject is overwhelming, and no consensus has been reached, with a

31 ssively and express phenotypes indicative of overwhelming antigenic stimulus and tissue homing/cytoto

32 Overwhelming are a set of key stress-responsive kinases

33 Although we also confirmed overwhelming association at the LOXL1 locus, the key SNP

34 th HBV-associated ALF is characterized by an overwhelming B cell response apparently centered in the

35 SSA measurements are typically dominated by overwhelming background aerosol concentrations even in r

36 osensing platforms, it is synonymous with an overwhelming background signal that prevents the detecti

37 s where small features are masked by a broad overwhelming background.

38 Overwhelming bacteremia is a leading cause of death.

39 recognized long-term risk of splenectomy is overwhelming bacterial infection.

40 ponses employed by the host to deal with the overwhelming bacterial presence of the microbiota.

41 In view of the overwhelming benefit of statins in the reduction of card

42 up of 27 months, because the boundary for an overwhelming benefit with LCZ696 had been crossed.

43 Despite the overwhelming benefits of antiretroviral therapy (ART) in

44 Rhesus monkeys, however, showed an overwhelming bias toward male-distinctiveness.

45 Overwhelming, bipartisan support by voters exists for en

46 However, an overwhelming body of knowledge has accumulated in the fi

47 The overwhelming body of research on T regulatory cells (Tre

48 ed intercellular communications may place an overwhelming burden on the nervous system and account fo

49 ital organs, including lung and bone, is the overwhelming cause of breast cancer mortality and morbid

50 trigger checkpoints, CDC14 mutations pose an overwhelming challenge to genome stability, both generat

51 Considering the overwhelming changes that occurred during primate evolut

52 hylmercury inputs to the estuary by 25-200%, overwhelming climate-driven changes over the next decade

53 hes enable rapid reconstruction of TRNs, the overwhelming combinatorics of possible networks limits i

54 y assuming a tame solution and inaction from overwhelming complexity.

55 of the finite difference method can have an overwhelming computational cost in models with a high-di

56 erficial zone (SZ) due to the presence of an overwhelming concentration of nonspecific TGF-beta bindi

57 The overwhelming contribution of diesel compared to gasoline

58 ages to cause T lymphocyte proliferation and overwhelming cytokine production, which lead to toxic sh

59 Overwhelming data in both humans and mice reveal a clear

60 Overwhelming data suggest that oncogenic and neurodegene

61 Overwhelming data support the use of medical therapy as

62 However, mCRPC showed overwhelming de novo resistance to immune checkpoint blo

63 ubjected to thermal nanoimprint, there is an overwhelming degree of adhesion at the mold-polymer inte

64 ic health laboratories (PHLs) may experience overwhelming demand for testing, even while the prevalen

65 To survive overwhelming demands on the proteasome arising during en

66 le this may be thought of as secondary to an overwhelming desire for drugs, it could equally well ref

67 differ greatly, ranging from asymptomatic to overwhelming disease and death, having available both an

68 Issues are discussed as related to the overwhelming dominance of social determinants on oral di

69 Due to the overwhelming dominance of the zwitterionic form, however

70 ndation of this model is the theory that the overwhelming driver of cancer risk is mutations.

71 ee densities at finer scales, as well as the overwhelming effect of humans across most of the world.

72 We also observe an overwhelming effect of the established TCF4 locus.

73 count after therapy initiation highlight the overwhelming effectiveness of antiretroviral therapy in

74 he data and safety monitoring board owing to overwhelming efficacy.

75 utational analysis of a large dataset can be overwhelming, especially for novices.

76 Considering the overwhelming evidence about the effectiveness of primary

77 There is nonetheless overwhelming evidence both for the deleterious effects o

78 There is overwhelming evidence both in vivo and in vitro that tra

79 Despite overwhelming evidence for D2 receptors (D2Rs) in maintai

80 he absence of the protecting pigment and the overwhelming evidence for hydrogen peroxide (H(2)O(2))-i

81 moma, although there was significant but not overwhelming evidence for thyroid, parathyroid, lung, an

82 Overwhelming evidence indicates that an ultrasonography-

83 Overwhelming evidence now supports the presence of a dee

84 ived comparatively little attention, despite overwhelming evidence of a pivotal role for the PAG in c

85 With overwhelming evidence of change in habitats, biologists

86 This is despite overwhelming evidence of its unique role in causing a wo

87 Recent genetic studies have provided overwhelming evidence of the involvement of microglia-re

88 However, the overwhelming evidence shows that the quality of reportin

89 Overwhelming evidence shows the critical role of glycoly

90 Overwhelming evidence suggests that compromised neuropsy

91 Overwhelming evidence suggests that ischemia-reperfusion

92 Overwhelming evidence supports the endosymbiosis theory

93 There is overwhelming evidence that G-protein-coupled receptors (

94 Genetic epidemiology provides overwhelming evidence that genetic background has an imp

95 There is overwhelming evidence that ions are present near the vap

96 There is overwhelming evidence that leaf-internal isoprene increa

97 Despite overwhelming evidence that major depression is highly he

98 These data demonstrate that, despite overwhelming evidence that prevention of lymphocyte apop

99 Overwhelming evidence that relationships between univers

100 In disease states, there is overwhelming evidence that stress hyperlactataemia is a

101 There is now overwhelming evidence that the innate and adaptive branc

102 or analyzing the SOP fail to account for the overwhelming evidence that the wake/sleep transition is

103 timulate the immune system, and there is now overwhelming evidence that this drives chronic immune ac

104 Despite overwhelming evidence that transcriptional activation by

105 f locating rare oxoG residues embedded in an overwhelming excess of undamaged bases is especially cha

106 ically defective in TLR4 signaling developed overwhelming, fatal rickettsial infections when given an

107 d by clinical homogeneity among patients, an overwhelming female predominance, production of a multil

108 eas biases can come from myriad sources, the overwhelming focus of the discussion to date has been on

109 Finally, the complex nature of plasma was overwhelming for HD1, but we define conditions for the t

110 ions based on molecular profiling results is overwhelming for many oncology clinicians and researcher

111 cant.] Upper-bound estimates suggest that an overwhelming fraction (90%) of these losses is due to th

112 Histopathology revealed an overwhelming fungal burden in the lungs of these complem

113 The present findings indicate that the overwhelming GABAergic drive present at the DMV is prima

114 es include the relatively acute, severe, and overwhelming health consequences of armed conflict, food

115 ts exciting scientific challenges as well as overwhelming health, equity, and economic benefits.

116 ontrol of an illegal trade in which there is overwhelming historical evidence of its complicity.

117 This overwhelming historical success makes it very difficult

118 , but in the clinical setting are limited by overwhelming host material and ultra-low target frequenc

119 es a novel function of the H4R preventing an overwhelming immune reaction by engagement of a negative

120 Mothers were of overwhelming importance for child survival and could not

121 Our results highlighted the overwhelming importance of corn agriculture within virtu

122 as never been clearly elucidated despite its overwhelming importance to Li-ion battery operation and

123 tions of shift effects under inhomogeneities overwhelming individual chemical identities, and model-f

124 This system could help PMNs cope with an overwhelming infection by A. actinomycetemcomitans.

125 Interestingly, despite overwhelming infection later in disease, evidence for si

126 An overwhelming infection of hepatocytes was a major conseq

127 In contrast to the overwhelming infection seen in the mice challenged with

128 ighly susceptible to fatal ehrlichiosis, had overwhelming infection, and developed extensive tissue i

129 of STAT1 mutation is ultimately fatal due to overwhelming infection.

130 of the CB2R during the immune response to an overwhelming infection.

131 nia, a condition linked to increased risk of overwhelming infections, remain largely unknown.

132 ages, leading to early onset, recurrent, and overwhelming infections.

133 nvading pathogens is essential to preventing overwhelming inflammation and sepsis that are symptomati

134 vation syndrome (MAS) is an acute episode of overwhelming inflammation characterized by activation an

135 diseases characterized by a cytokine storm, overwhelming inflammation, multiorgan dysfunction, and d

136 his might be important to avoid sustained or overwhelming inflammation, our data suggest that a negat

137 Here, we show that VML injury incites an overwhelming inflammatory and fibrotic response that lea

138 Controlling the overwhelming inflammatory reaction associated with polym

139 induces organ failure and is accompanied by overwhelming inflammatory response and impairment of mic

140 ection, and this resistance is not due to an overwhelming inflammatory response to infection.

141 unodeficiencies that share susceptibility to overwhelming inflammatory responses to certain infectiou

142 eroxia, but this effect is less prominent if overwhelming injury is induced by the combination of hyp

143 ous models of abdominal sepsis because of an overwhelming innate immune response, leading to prematur

144 and attractive target for modulation of the overwhelming innate immune response.

145 Despite overwhelming interest in the impact exerted by recombina

146 red to simulate cellular crowding, introduce overwhelming interferences to mass spectrometry (MS) ana

147 ons for fluorescent dye molecules due to the overwhelming isoenergetic fluorescence signal.

148 e parasite species, resulting in potentially overwhelming levels of complexity.

149 Overwhelming lines of epidemiological evidence have indi

150 sence of adequate compensatory regeneration, overwhelming liver damage can cause acute liver failure

151 olving hundreds of introns and genes with an overwhelming loss of IR in erythroid cells and MKs compa

152 Overwhelming lung inflammation frequently occurs followi

153 Streptococcus pneumoniae is thought to limit overwhelming lung inflammation in response to bacterial

154 zero positive end-expiratory pressure caused overwhelming lung injury, subsequently shown by others t

155 depletion of NK cells, which resulted in an overwhelming lung tumor burden relative to that in anima

156 The overwhelming majority (76%) of the insertions were distr

157 The overwhelming majority (95%) of well-resolved gamma dupli

158 The overwhelming majority (97%) of alpha-satellite DNA is fo

159 ch incorrect candidate locations consumes an overwhelming majority of a modern read mapper's executio

160 The overwhelming majority of acyl groups associated with mem

161 sis of nearly 400 genomes indicates that the overwhelming majority of bacteria possess homologs of th

162 rved as the archetypal organism on which the overwhelming majority of biochemical characterizations o

163 amin 1 and 3, which together account for the overwhelming majority of brain dynamin, cooperate in sup

164 astasis of breast cancer cells to bone in an overwhelming majority of breast cancer patients.

165 asive and metastatic stages accounts for the overwhelming majority of cancer deaths.

166 An acceptable formation model for the overwhelming majority of chondrules, however, has not be

167 ich proteins (OmcA and OmcB), constitute the overwhelming majority of COMC proteins.

168 To date, however, the overwhelming majority of experimentally realized single-

169 Furthermore, an overwhelming majority of genetic variants within or near

170 Mll1 and Mll2 complexes, is required for the overwhelming majority of H3K4 methylation at Hox loci.

171 oss-comparison of assemblies showed that the overwhelming majority of HGT candidates in the Boothby e

172 From 2006 to 2009, the overwhelming majority of hospitalizations or ED presenta

173 hed active variants up to 2,800-fold from an overwhelming majority of inactive ones at approximately

174 stablished that aerobactin accounted for the overwhelming majority of increased siderophore productio

175 We observe that the overwhelming majority of initially photogenerated single

176 The overwhelming majority of insertions were associated with

177 Although the overwhelming majority of intertwines between the parenta

178 nto the human genome, we discovered that the overwhelming majority of intronic and exonic RE are expr

179 emerged in all 3 serovars and is seen in the overwhelming majority of isolates, while resistance to t

180 However, as expected, we observed that the overwhelming majority of latently infected B cells at th

181 However, an overwhelming majority of liquids possess anisotropy in p

182 Unfortunately, spectral selectivity of the overwhelming majority of metamaterials that are made of

183 The overwhelming majority of Msp2 variants expressed during

184 Though the overwhelming majority of natural processes occur far fro

185 ypes of supernova are thought to produce the overwhelming majority of neutron stars in the Universe.

186 low, supporting a nonstroke etiology to the overwhelming majority of original events.

187 sequencing (NGS) technologies, results in an overwhelming majority of partial-length protein predicti

188 al-regulated kinase inhibitor treatment, the overwhelming majority of patients eventually acquire res

189 conclusion, COL7A1 harbored mutations in the overwhelming majority of patients with dystrophic epider

190 significant improvement in the lives of the overwhelming majority of patients.

191 g and MNase HS regions) may give rise to the overwhelming majority of phenotypic variation, greatly n

192 er, these CapSeq tags failed to identify the overwhelming majority of piRNA loci.

193 However, the overwhelming majority of previously reported temperature

194 mber of sequenced genomes rapidly grows, the overwhelming majority of protein products can only be an

195 The overwhelming majority of pseudoviruses fully released GF

196 induced long-term IPCC allograft survival in overwhelming majority of recipients.

197 e acetylation marks have been described, the overwhelming majority of regulatory genomics studies foc

198 s electric activity/asystole is growing, the overwhelming majority of research in risk stratification

199 irect response to metabolic deficit, yet the overwhelming majority of research on the biology of food

200 The overwhelming majority of respondents thought that incide

201 sition of kanamycin-resistance results in an overwhelming majority of revertants with MCMs.

202 We found that an overwhelming majority of rhythms obeyed a 1/f(beta) powe

203 y the male population, which constitutes the overwhelming majority of smokers in China.

204 The overwhelming majority of sports-related sudden deaths oc

205 The overwhelming majority of studies aiming to understand ub

206 However, the overwhelming majority of studies demonstrate the presenc

207 However, the overwhelming majority of studies examining this relation

208 the active sites of oxidoreductases, yet the overwhelming majority of studies on small-molecule mimic

209 Notably, although the overwhelming majority of such editing events occur in tr

210 Because the overwhelming majority of T1r3-expressing taste cells als

211 The overwhelming majority of these edits were of the A-to-I

212 However, the overwhelming majority of these patients inevitably acqui

213 classical colicin-like nuclease toxins, the overwhelming majority of toxin systems with the SUKH sup

214 press transforming viral oncoproteins in the overwhelming majority of tumor cells.

215 The overwhelming majority of UTIs are caused by uropathogeni

216 Because the overwhelming majority of variants are present in only a

217 Moreover, the overwhelming majority of variants, both somatic and germ

218 s and assemble into homomeric complexes, the overwhelming majority of which (>96%) are symmetric.

219 ustry products are made using catalysts, the overwhelming majority of which are heterogeneous catalys

220 Foods contain microorganisms, the overwhelming majority of which are nonpathogenic, some a

221 encoding 278 unique L4 and L22 proteins-the overwhelming majority of which are novel.

222 ated in patients with advanced fibrosis, the overwhelming majority of whom had NASH.

223 LAC was absent in an overwhelming majority of women with exclusively early re

224 ng variants identified per individual can be overwhelming, making it prudent to focus on noncoding re

225 d depth of the defects, and therefore is the overwhelming method of choice for use in diagnostics.

226 injury coexist, providing the basis for the overwhelming morphologic and clinical heterogeneity of A

227 In order to make sense of the overwhelming mutational data and capitalize on this clin

228 n seeds arrived in extremely high densities, overwhelming niche-based mortality factors.

229 clinicians and scientists now have access to overwhelming number of available databases capturing pat

230 In the last decade, an overwhelming number of genetic aberrations have been dis

231 The overwhelming number of genetic alterations identified th

232 Despite the overwhelming number of human long non-coding RNAs (lncRN

233 The overwhelming number of new catalysts and conditions rece

234 Due to the overwhelming number of passenger mutations in the human

235 Managing the overwhelming numbers of molecular states and interaction

236 This financial burden is an overwhelming obstacle for Haiti's poorest citizens, and

237 ighly regulated repair pathways, potentially overwhelming orderly repair and creating sustained fibro

238 s the major contributor to Pb contamination, overwhelming other potential local and transboundary sou

239 s opioids works to close this gate, reducing overwhelming pain generated by parallel pathways.

240 erior population survival during a simulated overwhelming pandemic.

241 e essential, but the scale of the task risks overwhelming parliament and the civil service.

242 scale and open-ended questions demonstrated overwhelming participant satisfaction with course conten

243 etween giving explicit information while not overwhelming patients and being realistic while remainin

244 s and clinical presentation of patients with overwhelming postsplenectomy infection (OPSI).

245 dity and mortality in these patients are the overwhelming postsplenectomy sepsis and development of l

246 k were IgA isotype, in stark contrast to the overwhelming predominance of IgG isotype Env-specific B

247 standing feature of these assemblages is the overwhelming predominance of monothalamids, a group ofte

248 This overwhelming preference for H shift is consistent with B

249 Experienced divers had an overwhelming preference for natural reefs.

250 trained for 4 or 7 d in the MWM exhibited an overwhelming preference for swimming in a direction rela

251 f prokaryotic type were characterized by the overwhelming presence of omega-3 C18 polyunsaturated fat

252 the search for novel approaches to blunt the overwhelming pro-allergic Th2 response, we evaluated the

253 evidence that complement activation provokes overwhelming pro-inflammatory responses, whether or not

254 that most septic patients do not die from an overwhelming proinflammatory immune response but in an i

255 Aggregation does not arise because of overwhelming proteasome-mediated degradation but because

256 yndrome (ARDS), are devastating disorders of overwhelming pulmonary inflammation and hypoxemia, resul

257 Given the overwhelming quantity of information available from the

258 Also notable was the overwhelming reduction in mast cell transcripts, potenti

259 poisoning may be related to interrupting or overwhelming relevant regulatory or signaling process(es

260 Although the results revealed overwhelming satisfaction with the IACUC administrative

261 unoglobulins, the patient ultimately died of overwhelming sepsis.

262 mmunomodulating therapy, the patient died of overwhelming sepsis.

263 also affect leading-edge sex ratios, perhaps overwhelming sex-biased dispersal.

264 ies and the consensus of the literature that overwhelming similarities (and not differences) exist be

265 stabilizing due to large exchange repulsions overwhelming stabilizing charge-transfer terms.

266 ior is often conceptualized as a response to overwhelming stress.

267 mance generalists, which helps explain their overwhelming success as a group.

268 atments built on these theories have claimed overwhelming success despite insufficient evidence.

269 elationship can be established because of an overwhelming success in ablation.

270 Motivated by the overwhelming success of genome-wide association studies,

271 s an intriguing feature and critical for the overwhelming success of higher plants.

272 ecently, 5 major randomized trials showed an overwhelming superior benefit of combining endovascular

273 We find overwhelming support for a long-term decline across all

274 ral snakes in both space and time, providing overwhelming support for Batesian mimicry.

275 and analyses of molecular variance provided overwhelming support for the existence of at least two i

276 42(fl/fl) mice died at 3 weeks of age due to overwhelming suppurative upper airway infections that we

277 he microbiota and its immune system to avoid overwhelming systemic immune activation, humans have evo

278 In severe trauma, overwhelming systemic inflammation can result in additio

279 Overwhelming systemic inflammatory responses may suppres

280 this data bonanza comes the computationally overwhelming task of analysis.

281 educed Treg recruitment to the kidney and an overwhelming TH1 immune response, with an aggravated cou

282 The evidence is now overwhelming that partially assembled nucleosome states

283 nts in a dose- and motor-dependent manner by overwhelming the ability of Aurora B to mediate error co

284 ific variation in these responses was large, overwhelming the average community response.

285 ting condensation level (LCL) with elevation overwhelming the effects of decreasing total column wate

286 g the lowest LUMO level recorded for an NDI, overwhelming the formative tetracyanoquinodimethane (TCN

287 ce 2009, the economic recovery increased TF, overwhelming the influence of improved emissions intensi

288 , and complexity of environmental change are overwhelming the intrinsic capacity of corals to adapt a

289 ing and impair the transport to the GA, thus overwhelming the quality control mechanism in the ER.

290 e presence of large fluorescence backgrounds overwhelming the RR signals.

291 een sometimes described as "compelling" and "overwhelming", there are limitations that existing studi

292 ecruit and maintain rare blood donors is not overwhelming, there are quite a few pearls.

293 mmunosuppressive mediators that help prevent overwhelming tissue damage.

294 ntations of significant sequence hits can be overwhelming to the user.

295 h tree-killing bark beetles are critical for overwhelming tree defenses and incurring host tree morta

296 scovery of new phages and help interpret the overwhelming unknown sequences in the viral metagenomics

297 associated with death at an early age due to overwhelming viral infection (complete STAT1 deficiency)

298 During persistent infection, overwhelming viral replication and the rapid loss of ant

299 e full spectrum of research grapple with the overwhelming volume of data being generated daily and a

300 The initial output of these studies has been overwhelming, with over 150 risk loci identified in stud