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1 ic diagnosis was made in 56 families (36.8%) owing to 57 (likely) pathogenic variants in 50 genes alr
2 a durable effect on long-term graft survival owing to a combination of drug toxicities and the emerge
3                                              Owing to a complex history of host-parasite coevolution,
4 , and yet, glucose tolerance did not change, owing to a doubling of insulin sensitivity.
5  good combination of strength and plasticity owing to a dual-hierarchy in eutectic length-scales in t
6 uded, 1052 (39%) were defined as higher risk owing to a family history of melanoma, multiple primary
7 was similar between 1- and 2-muscle surgery, owing to a greater number of less symptomatic undercorre
8 was the absence of JAK2 mutations (P=0.001), owing to a high risk of death without relapse.
9  absence of RAS pathway mutations (P=0.004), owing to a high risk of relapse, and the presence of JAK
10 asibility is currently unproven, potentially owing to a lack of compatible donors, and is associated
11 period is rare and lacks robust chronologies owing to a lack of direct dating applications, poor pres
12 ase epidemiology and ZIKV evolution, in part owing to a lack of genomic data.
13 fluence oxidants may change with climate and owing to a lack of palaeo-records with which to constrai
14 their affinities have remained controversial owing to a lack of preserved diagnostic characters.
15                                     However, owing to a lack of structural information, the mechanism
16                                              Owing to a large diamagnetism, graphene flakes can respo
17 the therapy after only 4 cycles of treatment owing to a life-threatening progression of the disease.
18                                              Owing to a long-term development of reducing the sizes o
19 ion of the data and safety monitoring board, owing to a low likelihood of benefit and evidence of the
20 tructure and find that habitat fragmentation owing to a natural barrier has resulted in strong geneti
21 te tolerance, none are currently recommended owing to a paucity of supportive clinical data.
22 rly evolution of termitophily is challenging owing to a scarcity of fossil termitophiles, with all kn
23 phene are perfect one-dimensional conductors owing to a set of gapless states that are topologically
24 issibility of L. donovani by infected hosts, owing to a systemic effect that exposure to bites has on
25     Most patients stopped or used no opioids owing to adequate pain control, and 16% to 29% of patien
26                                              Owing to advances in monitoring and imaging, there is no
27 et (or exceeded) by a thermodynamical effect owing to advection of warmer air masses.
28 hdrew consent or discontinued prematurely, 6 owing to adverse events attributed to X-82 including leg
29 ntage of patients who discontinued treatment owing to adverse events was 1% or lower.
30 f patients discontinued the assigned regimen owing to adverse events.
31 though 17% of participants discontinued X-82 owing to AEs, those who completed the study had lower th
32                         We propose that MFF, owing to affinity for narrow mitochondria, acts as a mem
33 sarcoplasmic reticulum Ca(2+) levels, likely owing to altered cellular excitability as a result of BP
34 early (MD better than -6 dB) loss, primarily owing to an elevated false-positive response rate.
35 ive capacity to targeted molecular therapies owing to an established network of signalling cascades w
36 this hypothesis has not been formally tested owing to an inability to purify or track these progenito
37 conduction abnormalities and premature death owing to arrhythmia.
38 egative regulatory proteins (CRPs), possibly owing to bisretinoid accumulation, may be responsible fo
39       These cells are defective in apoptosis owing to blocked degradation of Mcl-1, a pro-survival Bc
40 th a high probability of sharing specificity owing to both conserved motifs and global similarity of
41 has been difficult to selectively manipulate owing to cellular heterogeneity in this region.
42                               Health impacts owing to changes in ambient particulate matter with an a
43 ating HSP72 inhibitors in cells is difficult owing to competition with the high affinity and abundanc
44 etween DOC and free copper ion concentration owing to complexation by predominantly organic ligands.
45 ndomization (MR) methodology to control bias owing to confounding and reverse causation.
46 nts aged >/=6 years with ocular misalignment owing to congenital or acquired paralytic or comitant st
47 s fail to converge to form glomeruli, likely owing to contact-mediated repulsion between axons expres
48  of approved prescriptions were never filled owing to copay.
49 irst incident myocardial infarction or death owing to coronary heart disease, and stroke, defined as
50 creased vision attributable to macular edema owing to CRVO or HRVO.
51         Vessel function was further improved owing to decompression of intratumoral vessels as a resu
52  fellow eyes, the increase in ACA was mainly owing to decreased iris curvature.
53                                              Owing to deep theoretical roots and apparent generality,
54 ive forcing in areas with wildfire influence owing to depletion effects on composition.
55 ased studies have been conflicting, possibly owing to different methods to assess SDB or cognitive do
56 ndels to cancer has been largely unexplored, owing to difficulties in detecting them in short-read se
57 er ecological niche models are still lacking owing to difficulties in evaluating forecasts using real
58  this hypothesis remains inadequately tested owing to difficulties in reconstructing terrestrial pale
59 s that appear in multiple regions of a tumor owing to dispersion throughout the tumor.
60           Thirty-nine patients were excluded owing to emergent pre-endovascular therapy intubation.
61 ivity in the western North Pacific, which is owing to enhanced subtropical deep convection and favora
62         tritici (Pgt) but are often overcome owing to evolution of new virulent races of the pathogen
63 t glutamine is often depleted at tumor sites owing to excessive cellular consumption and poor vascula
64 cing response time of electricity generation owing to fast mass transport through pressure-driven flo
65 tive, energy-rich species, but are resilient owing to favourable Franck-Condon factors.
66 euro2348) than in the heparin arm (euro6744) owing to fewer admission days related to treating CVC-re
67                                              Owing to field concentration in the metamaterial at reso
68 learance pathways varies between individuals owing to genetic differences and similarities and differ
69 -damage response (DDR) are often tumor prone owing to genome instability caused by oncogenic challeng
70 y have the best diagnostic potential, partly owing to having no areas excluded for being larger than
71 limited guidance in clinical decision making owing to heterogeneity and scarcity.
72 c and idiolectal variation-genetic variation owing to heterogeneity in ancestry within admixed groups
73 risk of cardiovascular disease (CVD) in part owing to hypertriglyceridemia and low high-density lipop
74                                      Failure owing to hypotony occurred in 0.4% of the Ahmed group an
75 the outer retina associated with papilledema owing to idiopathic intracranial hypertension (IIH) at p
76 as a smaller contributor to total cost (24%) owing to increased costs from room and board (mean [SD]
77 significantly reduced number of HSCs, likely owing to increased differentiation of HSCs toward myeloi
78 e and patients, hepatic S1P levels increased owing to increased hepatic sphingosine kinase-1 expressi
79 from 21.0 to -163.8 g CO2 -eq m(-2) , mainly owing to increased net CO2 uptake.
80 r to document eating times may be misleading owing to individual differences in circadian timing rela
81  mothers undergoing immune system activation owing to infections or autoinflammatory syndromes.
82 ole system increases with decreasing density owing to inter-carrier interactions.
83 thods can introduce systematic errors (e.g., owing to interconversion among metabolites) and how prop
84  sources of anxiety were fear of going blind owing to intravitreal injections and concerns about trea
85 al challenge of the mutant viruses, possibly owing to its ability to mediate antibody-dependent cellu
86                                              Owing to its bonding characteristic, most carbon allotro
87 logy practices, MIPS may be more appropriate owing to its broader applicability and the current pauci
88 onformational change upon adsorption to NPs, owing to its capability to label the primary amines expo
89                                              Owing to its chemical complexity, BrC is separated by mo
90                                              Owing to its chemical properties, tyramine can react wit
91 e measurement technique for this application owing to its dependence on the diffusional potentials of
92 e with an unprecedented selectivity of 100, owing to its distinctive pore topology with large heart-
93 the metabolism and survival of all organisms owing to its function as a cofactor of enzymes collectiv
94    The Mg/S couple is of particular interest owing to its high energy density and low cost.
95 lectrolyte exhibits great promise for SSLiBs owing to its high Li-ion conductivity, wide potential wi
96 capacity anode, but faces several challenges owing to its high reactivity and uncontrolled dendrite g
97  of nitric oxide, is a significant challenge owing to its high reactivity with biological thiols (wit
98              RSQ2 performed better than RSQ1 owing to its higher open-circuit voltage (Voc) and fill
99                                              Owing to its important role in bacterial behavior, its a
100  resource in the signal transduction pathway owing to its low abundance relative to its binding partn
101 protein is an attractive therapeutic target, owing to its multifunctionality in virus replication and
102  has recently received significant attention owing to its remarkable capability of enabling subwavele
103 hus, although this study has inherent biases owing to its retrospective nature, concern regarding an
104 ike breast cancer (BLBC) with poor prognosis owing to its role in promoting epithelial-to-mesenchymal
105                          Amorphous selenium, owing to its tremendous technological importance and per
106 especially for using a photophysical process owing to its tunable properties.
107 aphy is the quintessential imaging technique owing to its unique ability to provide real-time images
108 ants to climate change is poorly constrained owing to large uncertainties in the degree to which proc
109 PPIs with small molecules can be challenging owing to large, hydrophobic binding surfaces.
110           Receiving a solid organ transplant owing to late-stage organ failure, followed by long-term
111 ze of the different members of the Ln series owing to lattice strain effects induced by changing the
112 ell walls to enzymatic conversion, primarily owing to lignin.
113                                              Owing to limitations in acquiring cells from healthy hum
114 us mutations have been ineffectively purged, owing to limited recombination in the cassava genome; (i
115 pressed survival motor neuron (SMN) protein, owing to loss of the SMN1 gene.
116 fite-sequencing poses statistical challenges owing to low and uneven sequencing depth, as well as the
117                                     However, owing to low bioavailability and poor skin permeability,
118 y, although with a high level of uncertainty owing to low event rates.
119           Bankart ICCs were not significant, owing to low prevalence.
120 ger than those on the Sun) convective cells, owing to low surface gravity.
121             Extubation is often unsuccessful owing to lung disease or inadequate respiratory drive.
122 FDG was greatest and continuously increasing owing to metabolic trapping through phosphorylation by h
123 parison with previous estimates is not ideal owing to methodological differences, our results are con
124 ed regular internet use (denominators varied owing to missing data).
125 ced increase in cytosolic calcium is blunted owing to mitochondrial calcium sequestration, and calciu
126                    The difference was mostly owing to more primary donor failures in the 8-14d PT gro
127 uroendocrine tumours (PanNETs) is increasing owing to more sensitive detection methods, and this incr
128 toms reach a very high degree of ionization, owing to multiphoton absorption, which in a heteronuclea
129 n thus frequently exhibits a transformation, owing to multiple possibilities caused by incompatible i
130 ns clinically mimic rheumatologic conditions owing to non-specific arthralgia and back pain.
131 ed in scale and susceptible to contamination owing to nonspecific adsorption and desorption on the su
132  than in HC group (16.9 +/- 5.8), especially owing to number of missing teeth (RA = 6.0 +/- 5.4, HC =
133                                              Owing to our ability to selectively control the magnetiz
134 ow that GMP clusters are constantly produced owing to persistent activation of the self-renewal netwo
135  on beta-cells, wherein continued DNA damage owing to persistent oxidative stress results in p53 acti
136                               Adverse events owing to PHS are costly and represent a quality improvem
137  causes adverse pregnancy and birth outcomes owing to Plasmodium falciparum accumulation in the place
138 reatment response to binocular treatment was owing to poor treatment adherence or lack of treatment e
139 ow greater infection in provisioned habitats owing to population growth and food-borne exposure to co
140 blanking period" (when arrhythmias may occur owing to postablation inflammation), there were 680 epis
141 y 3A4 is often a concern in drug development owing to potential drug-drug interactions and the variab
142 the percentage of postintervention SICU days owing to potentially avoidable admissions (152 of 1168 d
143  to Candida albicans in patients with EoE is owing to pre-existing disease and its underlying abnorma
144             If a patient required lensectomy owing to progression of ROP and/or presence of lens opac
145 opausal than in premenopausal women, perhaps owing to protective effects of estrogens.
146 ersons compared with white persons, possibly owing to racial differences in the glycation of hemoglob
147 did not start tuberculosis treatment, mostly owing to rapidly deteriorating clinical conditions or lo
148 xed groups [25, 26] and idiolectal variation owing to recent language formation from differentiated s
149 2-year-old girl was referred to our hospital owing to repeated anaphylactic reactions induced by exer
150                                              Owing to S4s' compatibility with the standard printed ci
151 n of high school students attempting suicide owing to same-sex marriage implementation.
152 ion after heating at 55 degrees C for 10 min owing to sedimentation of LCMs.
153 arate architecture and substrate specificity owing to several potential target bonds within the react
154                     Rates of discontinuation owing to side effects were 35% for INH, 21% for RIF, and
155 okers differed in whole-brain SUVs (P=0.006) owing to smokers having 16.8% lower values than non-smok
156                                              Owing to species-specific differences in liver pathways,
157                      Unsteady modules happen owing to strengthen links among funds during the time th
158 efined as the first nonfatal stroke or death owing to stroke.
159 ut they diverged in their chemical evolution owing to subsequent fractionation by nebular and planeta
160 usen (ODD), and 3 children (6 eyes) with PPE owing to superficial ODD were included.
161 yes) with PE, 11 children (19 eyes) with PPE owing to suspected buried optic disc drusen (ODD), and 3
162 ell-appearing infants who presented for care owing to symptoms that placed them at increased risk of
163 ificial systems typically lack applicability owing to synthetic challenges and structural complexity.
164 rn preterm are expressed prior to birth, but owing to technical limitations, this has been difficult
165                                              Owing to the 1T' structure of ReS2x Se2(1-x) alloys, the
166  anthropogenic-driven mass mortality events, owing to the ability to account for uncertainty in the a
167 gy of highly heterogeneous cell populations, owing to the ability to collect highly parametric proteo
168 ism of action of GDF15 are poorly understood owing to the absence of a clearly identified cognate rec
169  recognition by DASS remain obscure, largely owing to the absence of any substrate-bound DASS structu
170 efficacy is significantly variable in clinic owing to the absence of proper drugs and the lack of und
171 s, these inhibitors continue to be employed, owing to the absence of robust alternatives.
172 ionality over multiple cycles of actuations, owing to the anti-fatigue property of the hydrogel under
173 rds for assessing phototoxicity cannot exist owing to the breadth of samples and experimental questio
174 y trapped waves, the Kelvin and Yanai modes, owing to the breaking of time-reversal symmetry by Earth
175  of a stratosphere remains open to question, owing to the challenges posed by the highly variable hos
176  eliminated by performing catalysis in water owing to the change in mechanism.
177 ocal Universe, the systematic uncertainties (owing to the chosen stellar initial-mass function and th
178 ring disasters could challenge pediatricians owing to the close follow-up likely to be required.
179 interesting applications as food ingredient, owing to the coloring capacity and the presence of healt
180                                     However, owing to the complexities (both technical and logistical
181 which has been more challenging to implement owing to the complexity of molecular structures, has now
182  network enables larger property enhancement owing to the cooperative effects of both the increased c
183                                              Owing to the cooperativity of protein structures, it is
184  cost of MP $12330 (MP $2500), predominantly owing to the cost of surgical care (mean [SD] cost, MP $
185                                              Owing to the coupling between open Fermi arcs on opposit
186 nes possessing an aryl carbamate substituent owing to the direct attachment of an C(O)OSiR3 group to
187 bout the ancient origin of retroviruses, but owing to the discovery of their ancient endogenous viral
188  mixing always increases the kappa l of RMLs owing to the dominance of incoherent phonons.
189 nsiderable scientific inquiry, most recently owing to the dramatic collapse of juvenile recruitment [
190                                              Owing to the enhanced cellular uptake and P-gp suppressi
191 l DFT calculations reveal that the receptor, owing to the enhanced H-bonding ability of thiourea grou
192                                     However, owing to the exhaustive fragmentation following EI ioniz
193 uired to decipher the course of the reaction owing to the fact that the IR responses are perturbed by
194                                              Owing to the failure of the present pharmaceutical optio
195 n lesions using images is a challenging task owing to the fine-grained variability in the appearance
196 as no effect on tetramerization of RXRalpha, owing to the head-tail interaction that is absent in tRX
197                                              Owing to the high selectivity and cost-effective binding
198 etals have not been reported to date, likely owing to the highly reactive nature of low-valent niobiu
199 ar-IR absorption of the HNPs is blue-shifted owing to the hollow interior.
200 ral organic matter (NOM) conditioning films, owing to the hydrophilicity of NOM.
201 ite antagonist results in bleeding, possibly owing to the important role of PAR1 activation on cells
202 nd balance are often irreversible in mammals owing to the inability of cells in the inner ear to prol
203                                              Owing to the increased reaction interface area, the Janu
204                                              Owing to the independence of the two nonlinearities, the
205                                              Owing to the interfacial nature of the magnetism, the ab
206 escence microscopy faces a 'colour barrier', owing to the intrinsically broad (about 1,500 inverse ce
207                                              Owing to the inversion symmetry in bilayers, the photolu
208 e amide nonisolable at 35 degrees C and pH 4 owing to the joint presence of carboxy and carboxylate g
209 t this hypothesis has been difficult to test owing to the lack of a permissive in vivo model of HAdV
210 rvival rate ( 16%) of all tumor types partly owing to the lack of effective therapeutic agents.
211 t modulating these interactions is difficult owing to the lack of interaction mechanism.
212 ally from that in crystalline semiconductors owing to the lack of long-range order and high defect de
213 gth (826 MPa) and Young's modulus (65.7 GPa) owing to the large length and the alignment of nanofiber
214 % CI: 0.15, 3.2) for the 2009 H1N1 pandemic, owing to the late timing of the vaccination program in r
215 mains challenging to scale up these circuits owing to the limited number of designable, orthogonal, h
216 fficult to discern patterns of dissemination owing to the limited number of patients and available me
217                                              Owing to the limiting, comparatively low electronic cond
218 e velocity or optical depth of the outflows, owing to the long timescales of quasar variability.
219 s in large-scale energy storage applications owing to the low cost.
220                                     However, owing to the low radiation absorption of tumors, high do
221 on may proceed on molten salt state surfaces owing to the lower melting point of the used Na salts co
222                                              Owing to the many metabolic functions fulfilled by perox
223  physics in fractional quantum Hall systems, owing to the microscopic control and precision that is a
224                           Here we show that, owing to the much higher energy level for the Cu 3d(10)
225 ation and aggregation has proven a challenge owing to the multiple potential phosphorylation sites an
226 trics scales proportionally with V cr(-2.2), owing to the one-dimensional structural constraint on la
227                                              Owing to the outstanding conductivity and biocompatibili
228                                              Owing to the overall increase in herbal infusions' consu
229 he adult mammalian heart is non-regenerative owing to the post-mitotic nature of cardiomyocytes.
230 , fitness is at best a derived quantity, and owing to the potential complexity of such processes, the
231 ty of dynamical scenarios and instabilities, owing to the properties of the incoherent excitonic rese
232                      An interesting finding, owing to the proposed algorithm, is that the biggest hub
233 velopment of synthetically useful reactions, owing to the proximity-induced reactivity and selectivit
234                                              Owing to the rarity of severe necrotising enterocolitis,
235                                         Yet, owing to the rarity of these disorders, little clinical
236 ades, there is a paucity of prospective data owing to the rarity of this disease.
237 ult to investigate directly via experiments, owing to the reduced dimensions of the pores.
238 ch a wide spectral range remains a challenge owing to the rigidity of the resonator for the generatio
239                                              Owing to the screen-printed nature, such kind of biosens
240 it is almost impossible by thermal catalysis owing to the significant thermodynamic barrier.
241 terpretation of NGS data remains challenging owing to the size and complexity of the genome and the t
242    Despite the limited power of the analysis owing to the small sample size of those with impaired vi
243 se a major concern to public health, largely owing to the steadily increasing prevalence of drug resi
244                                              Owing to the steric hindrance of the axle phenyl group,
245                                      Second, owing to the strong van der Waals attraction between the
246 f stable isotope patterns in mammalian cells owing to the superimposition of different pathways contr
247                                              Owing to the tremendous diversity of organic molecular m
248  batteries has received increasing attention owing to the unique benefits of Mg metal electrodes, nam
249                                              Owing to the vast diversity of linkers, nodes, and topol
250 al breast cancer rates are declining as well owing to the widespread use of adjuvant systemic therapy
251 monooxygenases have attracted vast attention owing to their abilities to disrupt glycosidic bonds via
252 ultaneous depletion of both Satb1 and Satb2, owing to their antagonistic effect on the pluripotency r
253 olecular tags for magnetic resonance imaging owing to their biocompatibility and ease of incorporatio
254 tractive solution for practical applications owing to their biocompatibility and sustainability.
255 robeam have attracted considerable attention owing to their capability to grab and separate a single
256 omas, which are fixed in a mesenchymal state owing to their cells of origin.
257 tein drinks with good consumer visual appeal owing to their clarity.
258 a reputation for being difficult to produce, owing to their complex disulfide connectivity.
259 ce are a predictive TB drug development tool owing to their consistent development of human-like path
260 d an increasing importance in nanotechnology owing to their contributions to both fundamental and app
261  they avoided adhesive trapping in the brain owing to their dense PEG coating, which was critical to
262 s are at the frontiers of modern electronics owing to their discrete voltage regulated operational le
263  significant attention as cancer biomarkers, owing to their ease of access (circulating miRNA in the
264 oteases are highly sought-after drug targets owing to their essential roles in apoptosis, proliferati
265 sfully implemented using inorganic materials owing to their excellent electrical properties, however,
266 de perovskites attract unfaltering attention owing to their excellent photovoltaic properties.
267 ging findings demonstrating that TSCM cells, owing to their extreme longevity and robust potential fo
268 cted the tremendous attention of researchers owing to their fascinating electrical, thermal and physi
269                                              Owing to their generic system-independent nature, these
270 onately large influence on colloidal systems owing to their greater surface area; however, the challe
271 I)-are key tracers of accretionary processes owing to their high volatility and incompatibility, but
272 s, which have attracted significant interest owing to their integration with everyday life activities
273 ron and copper being particularly attractive owing to their low cost and non-toxicity.
274                                              Owing to their multivalency, polymeric IgM antibodies pr
275                                              Owing to their mutation-prone replicase and unique genom
276        Mushrooms have been used extensively, owing to their nutritional and medicinal value, for thou
277                                              Owing to their promise in photocatalysis and optoelectro
278                                              Owing to their rarity and histologic overlap, accurate d
279                                              Owing to their relatively high stability and activity, i
280                                              Owing to their reproducibility, stability, and cost-effe
281 d candidates as photoanode materials, mainly owing to their resistance to photocorrosion, non-toxicit
282  carrying biological entities are attractive owing to their sensitivity, selectivity, and minimally d
283 herapeutics including macromolecules is that owing to their size they are subject to cellular uptake
284                                              Owing to their small size and complicated chemical and p
285 tractive motifs for bioorthogonal chemistry, owing to their small size and unique modes of reactivity
286 ties for next-generation implantable devices owing to their soft mechanical nature that leads to mini
287 ective detection of a steroid is challenging owing to their structural similarities.
288 neffective for photochemical internalisation owing to their sub-optimal intracellular localisation.
289                                              Owing to their success in clinical practice, the prevale
290 mising materials for a range of applications owing to their unique crystal structure and optoelectron
291 t are distinct from other tissue macrophages owing to their unique homeostatic phenotype and tight re
292 omising lightweight EMI shielding materials, owing to their unique nanostructures and extraordinary e
293 l have received tremendous research interest owing to their unique structural features, fascinating p
294 us applications, but has had limited success owing to thermodynamic favorability of sphere formation.
295                                              Owing to these differences, Cvi-0 x Col-0 hybrid progeny
296 earching against a predefined glycan library owing to unanticipated modifications.
297 s vary sharply over short distances (<<1 km) owing to unevenly distributed emission sources, dilution
298 segment that had to be removed after 2 years owing to vascularization and corneal thinning.
299 ock hours of corneoscleral limbal dissection owing to wide tumor excision (8 vs 7; P = .12), were com
300                                              Owing to widespread resistance to these therapies, new d

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