ライフサイエンスコーパス: oxazolidine

1 lidine, a monomeric doxorubicin formaldehyde-oxazolidine.

2 ic form with synchronous ring opening of the oxazolidine.

3 e nucleophilic reagent to the oxygen atom of oxazolidine.

4 yde and epirubicin, which cannot form stable oxazolidines.

5 in the presence of iron salts to afford 1,3-oxazolidines.

6 ion of PhS(O)H, providing conjugated dienone oxazolidine 13.

7 the addition of diverse nucleophiles to the oxazolidine-2-one moiety accompanied by the release of c

8 the Diels-Alder reaction of N-2-alkenoyl-1,3-oxazolidine-2-one with cyclopentadiene.

9 y, the starting racemic material, adamantane-oxazolidine-2-one, was resolved into single enantiomers

10 eterocycles by decarboxylation of adamantane-oxazolidine-2-one.

11 Some glucosinolate derivatives such as oxazolidine-2-thione from progoitrin in brassica oilseed

12 wed by desulfonation (Al(Hg)), afforded keto-oxazolidine 20, which bears a (E)-Delta(6) double bond.

13 ring closure metathesis of 2-allyl-N-acroyl oxazolidines, 8.

14 -(13)C]capreomycidine (32) was prepared from oxazolidine aldehyde (18) via 1,1-dimethylethyl (4R,1'S)

15 sis of homopentafluorophenylalanine (6) from oxazolidine aldehyde 1 in 57% overall yield and in > 98%

16 lyzed and ZnI2-promoted in situ formation of oxazolidine, alkynyl zinc, and propargylamine intermedia

17 discussed considering a mechanism involving oxazolidine and iminium ions formed in situ followed by

18 route for the construction of functionalized oxazolidines and imidazolidines.

19 drolysis of the primary photoproducts, spiro-oxazolidines and thiazolidines, under mild conditions un

20 ation of pseudoprolines (i.e. serine-derived oxazolidines as another type of protecting group), a com

21 By using oxazolidine-based pseudoprolines (PsiPro) substituted by

22 % overall yields and six to seven steps from oxazolidine beta-methyl ester 4.

23 ienylethene, Z/E isomerization and acid-base oxazolidine change cause selective addressabilities.

24 resolution (CIDR) of trans-Fox (fluorinated oxazolidine) chiral auxiliary is reported.

25 sting of two molecules of the parent drug as oxazolidine derivatives bound together at their 3'-nitro

26 results in its conversion to the beta-amino oxazolidine dione observed under conditions used in our

27 Acid-mediated deprotection of the oxazolidine, followed by N-acylation and Birch reduction

28 diastereoisomers through an atroposelective oxazolidine formation.

29 also provide evidence that suggests that the oxazolidine forms in situ, since cotreatment with doxoru

30 from a readily available chiral fluorinated oxazolidine (Fox).

31 luoromethylated prolines, pseudoprolines and oxazolidines has been achieved.

32 Dithienylethene oxazolidine hybrid system connected through an isomeriza

33 yrenes under these conditions to provide 1,3-oxazolidines in a formal aminohydroxylation of the alken

34 -derived aldehyde 26, respectively, afforded oxazolidine intermediates 27 and 33.

35 control observed during the formation of the oxazolidines is best explained by the stereoelectronic e

36 ed aldehyde 4, followed by hydrolysis of the oxazolidine, liberation of the amino group, and N-acylat

37 ty to form cyclic formaldehyde conjugates as oxazolidine moieties and that the cyclic conjugates are

38 burn reaction leading to the formation of an oxazolidine-N-oxyl compound was observed by electron par

39 spectra were observed due to the presence of oxazolidine-N-oxyl derivatives.

40 lease doxazolidine (Doxaz), the formaldehyde-oxazolidine of doxorubicin that cross-links DNA to trigg

41 m as a dimeric formaldehyde conjugate of the oxazolidine of doxorubicin.

42 ons with carbonyl compounds to give bicyclic oxazolidine products in good overall yields.

43 This process affords oxazolidine products that can be easily manipulated to y

44 mmetric cyclization of an amino acid derived oxazolidine provided a key lactam intermediate 11, which

45 lation is found between the puckering of the oxazolidine ring and the peptide bond conformation.

46 M-2 beta-lactamase retain the carbons of the oxazolidine ring of clavulanate.

47 oped incorporating an additional substituted oxazolidine ring, and providing improved enantiocontrol

48 BH(4)/CeCl(3) or DIBAL-H), hydrolysis of the oxazolidine ring, liberation of the amino group, and ins

49 her with three methylene groups, two forming oxazolidine rings and one binding the oxazolidines toget

50 ectra of 2,4-disubstituted thiazolidines and oxazolidines that cannot be attributed to classical dipo

51 ns and the Pt-catalyzed isomerization of the oxazolidine to an amide under neutral conditions.

52 r cyclization of unsaturated aldehyde via an oxazolidine to prepare C-3-substituted tetrahydroisoquin

53 orming oxazolidine rings and one binding the oxazolidines together at their 3'-amino nitrogens.

54 incorporation of trifluoromethyl substituted oxazolidine-type pseudoprolines (CF3-PsiPro) into peptid

55 The bicyclic oxazolidines were obtained from chiral N-alkenylamino al

56 (3-methyl and 3-tert-butyl 2,2-diphenyl-1,3-oxazolidine) were synthesized; they had approximately th