ライフサイエンスコーパス: oxidative cleavage

1 ring following removal of the C-24 carbon by oxidative cleavage.

2 l-E)-beta-carotene following epoxidation and oxidative cleavage.

3 wo epoxides were detected as a result of the oxidative cleavage.

4 ](2+) clusters and O(2)-induced [4Fe-4S](2+) oxidative cleavage.

5 enzyme and suggests a possible mechanism for oxidative cleavage.

6 We demonstrate the unique oxidative cleavage activity of the CTB3 monooxygenase do

7 at modify double bonds of these compounds by oxidative cleavage and cis-to-trans isomerization.

8 of segmented polyurethanes (SPUs) to in vivo oxidative cleavage and hydrolysis constitutes a drawback

9 s to modify product compositions in both the oxidative cleavage and sulfide oxidation pathways are an

10 ndicate that H2 activation at 2 proceeds via oxidative cleavage at Ru with concomitant hydride transf

11 lkyl aryl sulfones is quickly accompanied by oxidative cleavage by atmospheric O2, leading to the for

12 Asp and tRNAPhe, were used as substrates for oxidative cleavage by Fe.bleomycin to facilitate definit

13 al dihydroxylation of the olefin with oxone, oxidative cleavage by the in situ-generated 3,4,5,6-tetr

14 hylmagnesium iodide to Grundmann's enone 28, oxidative cleavage, functional group modifications leadi

15 Folates in vivo undergo oxidative cleavage, giving pterin and p-aminobenzoylglut

16 been exploited to demonstrate chemoselective oxidative cleavage in substrates containing two double b

17 of RNA in the absence of added metal ion and oxidative cleavage in the presence of Fe(2+) and O(2).

18 Folates undergo oxidative cleavage in vivo, releasing a pterin aldehyde

19 In ABA biosynthesis, oxidative cleavage is the first committed reaction and i

20 Formation of the gamma-lactone through the oxidative cleavage is used to assign stereochemistry of

21 cus utilizes a combination of hydrolytic and oxidative cleavage mechanisms to degrade cellulose.

22 therapeutic small molecule, is generated via oxidative cleavage of 1,1-dithiooxalate (DTO) photosensi

23 The aerobic oxidative cleavage of 1,2-diols using a heterogeneous ca

24 Subsequent oxidative cleavage of 16a-d then provided tetrahydrofura

25 Oxidative cleavage of 19 (RuCl(3)/NaIO(4)) followed by e

26 This enzyme catalyzes the oxidative cleavage of 2,6-dichlorohydroquinone in the ca

27 G by PM followed by irreversible PM-mediated oxidative cleavage of 3-DG.

28 ABA is synthesized via an oxidative cleavage of 9-cis epoxy-carotenoids, the first

29 recombinant chicken BCO2 also catalyzes the oxidative cleavage of 9-cis-beta-carotene and the non-pr

30 Specifically, oxidative cleavage of [Me(2)Si(C(5)Me(4))(2)]M(RH) is fa

31 Only two of these six sites involved oxidative cleavage of a 5'-G.Pyr-3' sequence, but three

32 a key control step in ABA biosynthesis--the oxidative cleavage of a 9-cis xanthophyll precursor to f

33 radation of 1,2-dichloroethane (1,2-DCA) via oxidative cleavage of a C-H bond (Pseudomonas sp. strain

34 PhnZ is notable for catalyzing the oxidative cleavage of a carbon-phosphorus bond using Fe(

35 nt hormone abscisic acid is derived from the oxidative cleavage of a carotenoid precursor.

36 This approach utilizes the oxidative cleavage of a variety of beta-keto esters and

37 Oxidative cleavage of a variety of olefins to the corres

38 Oxidative cleavage of alkenes in aerobic conditions sugg

39 The enzyme also catalyzed the oxidative cleavage of alpha-carotene, beta-cryptoxanthin

40 solation of highly reactive formylsilanes by oxidative cleavage of alpha-silyl glycols is presented.

41 gulator abscisic acid (ABA) is formed by the oxidative cleavage of an epoxy-carotenoid.

42 Oxidative cleavage of arachidonate (C(20)) and linoleate

43 testing of compounds that are generated upon oxidative cleavage of arachidonate and linoleate esters

44 The key step features an oxidative cleavage of aza-bicyclo[3.2.2]nonene 14, which

45 The Fe2+-mediated oxidative cleavage of BamHI occurs between residues Glu7

46 ir corresponding carbonyl derivatives to the oxidative cleavage of benzyl ethers, whereas 2 has been

47 The oxidative cleavage of benzylic and allylic C-H bonds usi

48 genase (Bcdo), the enzyme that catalyzes the oxidative cleavage of beta,beta-carotene into two retina

49 The oxidative cleavage of beta-carotene resulted in increase

50 he purified enzyme preparation catalyzed the oxidative cleavage of beta-carotene with a Vmax = 197.2

51 ation of apo-10'-carotenoids, suggesting the oxidative cleavage of both carotenoids at their 9',10'-d

52 pimerizations (methylmalonyl-CoA epimerase), oxidative cleavage of C-C bonds (extradiol dioxygenase),

53 A photocatalytic method for the aerobic oxidative cleavage of C=C bonds has been developed.

54 The topic of this review is oxidative cleavage of carbohydrate polymers by lytic pol

55 species, which are also known to elicit the oxidative cleavage of carbon-boron bonds.

56 rotene 9',10'-oxygenase (BCO2) catalyzes the oxidative cleavage of carotenoids at the 9'-10' bond to

57 ses catalyze the non-heme iron(II)-dependent oxidative cleavage of catechols to 2-hydroxymuconaldehyd

58 Oxidative cleavage of cycloalkene-1-carboxylates, made f

59 Free radical-induced oxidative cleavage of DHA-PC promoted by myeloperoxidase

60 rotene 15-15'-oxygenase (BCO1) catalyzes the oxidative cleavage of dietary provitamin A carotenoids t

61 on of amines in addition to facilitating the oxidative cleavage of dithioacetals and dithioketals.

62 r mechanism of action is believed to involve oxidative cleavage of DNA and possibly also RNA degradat

63 While oxidative cleavage of DNA was observed for Cu(2+)(aq) un

64 A new reagent for the oxidative cleavage of DNA, (1,4,7-trimethyl-1, 4,7-triaz

65 ee carbon carbohydrates possibly formed from oxidative cleavage of early glycation products are invol

66 provide evidence that ABA is synthesized by oxidative cleavage of epoxy-carotenoids (the "indirect p

67 nyl) dialdehydes 14 and 19 are accessible by oxidative cleavage of extensively substituted cyclohexen

68 onooxygenases (LPMOs) are known to carry out oxidative cleavage of glycoside bonds in chitin and cell

69 ccharide monooxygenases (LPMOs) catalyze the oxidative cleavage of glycosidic bonds in recalcitrant p

70 ) are copper-dependent enzymes that catalyze oxidative cleavage of glycosidic bonds using molecular o

71 suggests the steps in the LPMO mechanism for oxidative cleavage of glycosidic bonds.

72 me chromophore phytochromobilin involves the oxidative cleavage of heme by a heme oxygenase (HO) to f

73 nd iron acquisition in many pathogens is the oxidative cleavage of heme by heme oxygenase (HO), yield

74 The oxidative cleavage of heme by heme oxygenases (HOs) to f

75 The final step in releasing iron is the oxidative cleavage of heme by HemO.

76 These proteins catalyze oxidative cleavage of heme to CO and biliverdin, and rel

77 Heme oxygenases (HO) catalyze the oxidative cleavage of heme to generate biliverdin, CO, a

78 The oxidative cleavage of heme to release iron is a mechanis

79 Os) contribute to this process by catalyzing oxidative cleavage of insoluble polysaccharides utilizin

80 Fe(II)/Fe(III) cofactor for the O2-dependent oxidative cleavage of its substrate.

81 only two known enzymes able to catalyze the oxidative cleavage of latex for biodegradation.

82 Surprisingly, BCO1 catalyzed the oxidative cleavage of lycopene to yield acycloretinal wi

83 azol-2-ylidene) has been synthesized by mild oxidative cleavage of Me3 SiSiMe3 using [(ITMe)2 Pd(0) ]

84 Oxidative cleavage of methoxy and methoxybenzene moiety,

85 myo-Inositol oxygenase (MIOX) catalyzes the oxidative cleavage of myo-inositol (MI) to give d-glucur

86 We show that alpha-AE will also catalyze the oxidative cleavage of N-acylglycines, from N-formylglyci

87 Oxalate oxidase (EC 1.2.3.4) catalyzes the oxidative cleavage of oxalate to carbon dioxide and hydr

88 Ozonolysis or oxidative cleavage of peracetylated allyl derivatives re

89 ctive chlorinating species promote selective oxidative cleavage of plasmalogens, liberating alpha-chl

90 ysaccharide monooxygenases (LPMOs) carry out oxidative cleavage of polysaccharides and are of major i

91 This chemistry may contribute to the oxidative cleavage of polyunsaturated fatty acyls that p

92 rotene 15,15'-oxygenase (BCO1) catalyzes the oxidative cleavage of provitamin A carotenoids at the ce

93 ly been shown to catalyze the O(2)-dependent oxidative cleavage of recalcitrant polysaccharides.

94 hagocytes kill encapsulated microbes through oxidative cleavage of surface carbohydrates, releasing g

95 A chemoselective oxidative cleavage of synthetic gracilioether B, 11-epi-

96 An unusual selective oxidative cleavage of the (SS)-isomer was observed and t

97 everal important processes in plants, is the oxidative cleavage of the 11,12 double bond of a 9-cis-e

98 ng 4-oxo derivatives by isoform 1A2, and the oxidative cleavage of the acetyl ester of vitamin A (ret

99 ion-aldol reaction, followed by CAN-mediated oxidative cleavage of the aldol product.

100 nverted to gamma-hydroxy-beta-amino acids by oxidative cleavage of the alkyne.

101 Oxidative cleavage of the allylic amines furnishes the a

102 hiosemicarbazones that had been generated by oxidative cleavage of the appropriate pyruvic aldehyde d

103 low molecular weight carboxylic acids after oxidative cleavage of the aromatic bond with two vicinal

104 a(4)-1,2-azaborete complex and the selective oxidative cleavage of the B-N bond of the 1,2-azaborete

105 substituted cyclohexane that is generated by oxidative cleavage of the bicyclic sesquiterpene beta-tr

106 yketones by sequential allylic oxidation and oxidative cleavage of the bridging double bond at the B/

107 H(3)CN solutions of 3-OTf with O(2) leads to oxidative cleavage of the C(1)-C(2) and C(2)-C(3) bonds

108 ion of the hydroxy group as a THP acetal and oxidative cleavage of the C,C-double bond provided a sta

109 ound with a vanadium catalyst results in the oxidative cleavage of the C-C bond between the aryl ring

110 ment of low-molar-mass fragments obtained by oxidative cleavage of the capsular polysaccharide of Hae

111 -O-allyl purine nucleosides (13a and 15) via oxidative cleavage of the carbon-carbon bond to the corr

112 se that increases substrate accessibility by oxidative cleavage of the chitin chains.

113 ordination to form a C H sigma complex, (ii) oxidative cleavage of the coordinated C H bond to give a

114 Oxidative cleavage of the cyclic stereotetrads yields te

115 We were also able to show that oxidative cleavage of the cyclopentene 1,5-CH insertion

116 After oxidative cleavage of the double bond of 13 and reductio

117 bination with subsequent decarboxylation and oxidative cleavage of the double bond, allows the highly

118 o limonoid 2 by a sequence consisting of (1) oxidative cleavage of the exocyclic double bond, (2) ste

119 hydrate-based radical precursor, followed by oxidative cleavage of the formed alkene.

120 e carboxyalkanoates can be generated through oxidative cleavage of the gamma-hydroxyalkenals with the

121 ippurate to benzamide and glyoxylate and the oxidative cleavage of the glycyl Calpha-N bond in N-benz

122 eme oxygenase provides further evidence that oxidative cleavage of the heme is the mechanism by which

123 TDO catalyzes oxidative cleavage of the indole ring of L-tryptophan (L

124 tions may be intermediates formed during the oxidative cleavage of the indole ring to give kynurenine

125 variety of conditions were examined for the oxidative cleavage of the key cyclopentene intermediate

126 Oxidative cleavage of the olefin to give an aldehyde fol

127 Oxidative cleavage of the pendant alkene provides access

128 ygenase, and an ABM family monooxygenase for oxidative cleavage of the polyketide moiety.

129 rdoheme product to biliverdin concluded that oxidative cleavage of the porphyrin macrocycle was speci

130 ified recombinant chicken BCO2 catalyzes the oxidative cleavage of the provitamin A carotenoids beta-

131 Oxidative cleavage of the recalcitrant plant polymer lig

132 Oxidative cleavage of the resulting 2-azabicyclo[2.2.1]h

133 s of the acetonide moiety of 41, followed by oxidative cleavage of the resulting diol, gave the aldeh

134 Subsequent oxidative cleavage of the ring originally derived from t

135 are nine-carbon fragments resulting from an oxidative cleavage of the side chain of atROL.

136 Stereospecific oxidative cleavage of the silyl tether in 42 and 43 prov

137 Oxidative cleavage of the styrene derivatives provided a

138 f (E)-3-iodo-2-methylprop-2-enal followed by oxidative cleavage of the terminal vinyl appendage and a

139 ygenase MtmOIV, normally responsible for the oxidative cleavage of the tetracyclic premithramycin B i

140 koxylation, and hydroxylation) and selective oxidative cleavage of thus synthesized 2-benzylfurans ar

141 amine 2,3-dioxygenase-1 (IDO1; IDO) mediates oxidative cleavage of tryptophan, an amino acid essentia

142 lic peroxide intermediates and the different oxidative cleavages of II.

143 that DOPA-protein cross-linking and 1,2-diol oxidative cleavage proceed via different mechanisms and

144 In the symmetric oxidative cleavage reaction at C15,C15' position by BCMO

145 c 1,3-propanyl esters designed to undergo an oxidative cleavage reaction catalyzed by a cytochrome P(

146 In polar solvent, the expected Blankespoor oxidative cleavage reaction is the major reaction pathwa

147 CCL-1 uses a selective copper(I)-dependent oxidative cleavage reaction to release d-luciferin for s

148 rmined through application of a CAN-mediated oxidative cleavage reaction.

149 In this manuscript we report that oxidative cleavage reactions can be used to form oxocarb

150 Features of the oxidative cleavage reactions of diastereomers of dimeric

151 Consecutive oxidative cleavage reactions of these products or the re

152 A sequence of oxidative cleavage/reductive amination/hydrogenolysis en

153 A sequence of oxidative cleavage/reductive amination/reductive cleavag

154 consistent with isotope effects reported for oxidative cleavage/reductive coupling occurring at trans

155 The oxidative cleavage requires the intermediacy of a hemike

156 t, reductive O2 activation induces selective oxidative cleavage, revealing the indestructible charact

157 through a two-step Hosomi-Sakurai allylation/oxidative cleavage sequence, which is followed by subseq

158 This maize genetic lesion also affects the oxidative cleavage step in ABA synthesis.

159 h 3'-OPO(3) and 3'-OH, and no evidence of 4'-oxidative cleavage termini with either metal.

160 d; this intermediate then undergoes C-H bond oxidative cleavage to give an iridium eta(1)-allyl hydri

161 P), anticipating cytochrome P450 3A-mediated oxidative cleavage to the NMP in hepatocytes.

162 can undergo consecutive reactions including oxidative cleavages to yield a chemically diverse group

163 ure and determined how the change in rate of oxidative cleavage varies from methane to decane.

164 promoted hydrolytic cleavage, but efficient oxidative cleavage was observed in the presence of a mil

165 n some examples such as styrene derivatives, oxidative cleavage was observed instead of epoxidation.

166 A possible mechanism for this unusual oxidative cleavage was proposed on the basis of the stud

167 the corresponding allenyl ether, followed by oxidative cleavage with N-methylmorpholine N-oxide and c