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1 which ATP is generated via glycolysis and/or oxidative metabolism.
2 tion to promote mitochondrial biogenesis and oxidative metabolism.
3 rapid in vivo hepatic clearance mediated by oxidative metabolism.
4 chondrial biogenesis and enzymes involved in oxidative metabolism.
5 ounts of energy, which is often generated by oxidative metabolism.
6 on to fatty acids in tissues with high lipid oxidative metabolism.
7 ameters critical for tissues with high lipid oxidative metabolism.
8 ing skeletal muscle mitochondrial number and oxidative metabolism.
9 tal glycolytic metabolism to a mitochondrial oxidative metabolism.
10 atty acids are the two primary substrates in oxidative metabolism.
11 ide (FMN), are two key cofactors involved in oxidative metabolism.
12 d 25-fold upon a switch from fermentation to oxidative metabolism.
13 abetes that are often linked with defects in oxidative metabolism.
14 s regulation of lipolysis, thermogenesis and oxidative metabolism.
15 otentially incapable of developing inducible oxidative metabolism.
16 e available source of radicals through their oxidative metabolism.
17 ply is significant and these cells engage in oxidative metabolism.
18 pment, concomitant with increased demand for oxidative metabolism.
19 d levels of MITF and PGC1alpha and decreased oxidative metabolism.
20 onstrated effects of diabetes medications on oxidative metabolism.
21 n about the mechanisms by which THs increase oxidative metabolism.
22 iated with an increase in glucose uptake and oxidative metabolism.
23 1 protects and preserves HSCs by restricting oxidative metabolism.
24 tophagy and help to explain how THs increase oxidative metabolism.
25 disturbed and presumably preserved cerebral oxidative metabolism.
26 entricular function and increased myocardial oxidative metabolism.
27 g this response may reflect the intensity of oxidative metabolism.
28 scription remodels mitochondria and enhances oxidative metabolism.
29 revalence of glycolysis and dysregulation of oxidative metabolism.
30 has been associated with aging and abnormal oxidative metabolism.
31 chondrial multienzyme complexes required for oxidative metabolism.
32 receptor alpha (PPARalpha) driven program of oxidative metabolism.
33 at exerts many of the pleiotropic effects of oxidative metabolism.
34 s shifted to the pentose phosphate cycle and oxidative metabolism.
35 cating reduced procession of ketones through oxidative metabolism.
36 hains of three acceptor proteins involved in oxidative metabolism.
37 criptional co-activator of genes involved in oxidative metabolism.
38 ine that preferentially utilized lactate for oxidative metabolism.
39 C-1 coactivators are important regulators of oxidative metabolism.
40 use through the pentose phosphate cycle and oxidative metabolism.
41 oplasmic reticulum stress, and mitochondrial oxidative metabolism.
42 pregulation of genes enhancing mitochondrial oxidative metabolism.
43 nsport which support high rates of sustained oxidative metabolism.
44 cose and lipid homeostasis and mitochondrial oxidative metabolism.
45 rain regions in many subjects and compromise oxidative metabolism.
46 dual self-sufficiency in both glycolysis and oxidative metabolism.
47 ve oxygen species resulting from an enhanced oxidative metabolism.
48 is an essential cofactor for key enzymes of oxidative metabolism.
49 ng activator of mitochondrial biogenesis and oxidative metabolism.
50 s for understanding the regulation of muscle oxidative metabolism.
51 turation of cerebral glucose utilization and oxidative metabolism.
52 ty acid oxidation, and mRNAs associated with oxidative metabolism.
53 ase and aldehyde oxidase are involved in the oxidative metabolism.
54 increased phospholipid species and decreased oxidative metabolism.
55 calculated to be 21, close to upper limit of oxidative metabolism.
56 r the non-invasive investigation of muscular oxidative metabolism.
57 technique that might provide a biomarker of oxidative metabolism.
58 P-MRS data, acquired at rest, as a marker of oxidative metabolism.
59 o the apnoea, there was no change in the non-oxidative metabolism.
60 n in the brain depends almost exclusively on oxidative metabolism.
61 the Z-line, and an incremental shift towards oxidative metabolism.
62 ry high energy demands, largely satisfied by oxidative metabolism.
63 esis that is of heightened importance during oxidative metabolism.
64 tochondrial-encoded transcripts and enhances oxidative metabolism.
65 oea, although there was no change in the non-oxidative metabolism.
66 ying the BRAF V600E mutation, which promotes oxidative metabolism.
67 ts of H2O2 as a product of host and pathogen oxidative metabolism.
68 changes in the transcriptional regulation of oxidative metabolism.
69 a transcriptional modulator of mitochondrial oxidative metabolism.
70 urcation point between T cell glycolytic and oxidative metabolism.
71 fate reduction or a mixture of reductive and oxidative metabolisms.
72 e characteristic of defects in mitochondrial oxidative metabolism (6.0 +/- 1.6 vs. 5.1 +/- 0.9, P = 0
73 originally envisioned as a necessary evil of oxidative metabolism, a product of an imperfect system.
74 same species to investigate whether enhanced oxidative metabolism also confers clomazone resistance i
76 phis exhibited up to 2-fold-higher levels of oxidative metabolism and .NO production than SYL-infecte
77 the present study, we found that defects in oxidative metabolism and 2-HG production confer chemosen
78 as obesity, which is associated with reduced oxidative metabolism and a lower type I fiber content in
79 e in rat liver microsomes revealed extensive oxidative metabolism and a propensity for metabolite swi
80 romotes the functional recovery of beta-cell oxidative metabolism and abrogates the induction of path
82 at these cellular effects, increased rate of oxidative metabolism and ATP production, occur in cultur
83 del of tight calcium-dependent regulation of oxidative metabolism and ATP synthase-dependent respirat
84 ochondrial fusion dynamics, ensuring maximum oxidative metabolism and avoidance of FA toxicity in sta
85 de evidence for the novel role Lcn2 plays in oxidative metabolism and BAT activation via an adrenergi
88 igated the effect of human mHtt fragments on oxidative metabolism and Ca(2+) handling in isolated bra
89 f terminal differentiation such as inducible oxidative metabolism and cell substrate adhesion were en
92 of the cell division cycle, suggesting that oxidative metabolism and DNA replication are not incompa
96 2 expression is crucial for CO modulation of oxidative metabolism and for conferring cytoprotection.
97 a fatty acid tracer, we have quantified BAT oxidative metabolism and glucose and nonesterified fatty
98 pathways is energetically backed by elevated oxidative metabolism and hence contributes to oxidative
99 ) is a potent transcriptional coactivator of oxidative metabolism and is induced in response to a var
100 od, we demonstrate the detection of cerebral oxidative metabolism and its modulation by administratio
103 young healthy control subjects, cold-induced oxidative metabolism and NEFA uptake per BAT volume and
104 e in stimulating genes that are important to oxidative metabolism and other mitochondrial functions i
106 ic acid ((18)FTHA), a fatty acid tracer, BAT oxidative metabolism and perfusion and glucose and nones
107 has evolved a panoply of metalloproteins for oxidative metabolism and protection against reactive oxy
108 and nontoxic, it exhibited poor stability to oxidative metabolism and relatively poor selectivity aga
109 prehensive bioenergetic analyses to evaluate oxidative metabolism and respiratory kinetics in mouse m
110 ich SFRP5 inhibits WNT signaling to suppress oxidative metabolism and stimulate adipocyte growth duri
111 ocks traffic through the channel and reduces oxidative metabolism and that this requires the unstruct
112 Rgamma target genes, as well as the shift to oxidative metabolism and the increased mitochondrial bio
113 Recovery involves: (1) resumption of normal oxidative metabolism and the restoration of myocardial e
115 ide group to limit the potential for in vivo oxidative metabolism and to achieve an acceptable pharma
116 -intrinsic nutrient supply for mitochondrial oxidative metabolism and to maintain cellular homeostasi
117 60%), (ii) this energy demand is met through oxidative metabolism, and (iii) the CBF response is medi
118 inamide adenine dinucleotide, as a result of oxidative metabolism, and CCK by increasing cytosolic Ca
119 proinflammatory cytokine secretion, impaired oxidative metabolism, and diminished M. tuberculosis-lys
120 ey regulator of mitochondrial biogenesis and oxidative metabolism, and essential for adaptive thermog
121 ulated transcriptional coactivators to drive oxidative metabolism, and increased their rates of FA ox
123 ift their reliance on glycolysis relative to oxidative metabolism, and studies in model systems have
124 hibition on lipolysis, fatty acid oxidation, oxidative metabolism, and thermogenesis in brown adipocy
125 ufficient to reduce mitochondrial Ca(2+) and oxidative metabolism, and to establish a pseudohypoxic s
126 chnique, complementary methods for assessing oxidative metabolism, and whether the P(i) --> ATP flux
127 l to test whether individuals with increased oxidative metabolism are be more sensitive to hepatotoxi
128 this argument is that animal models in which oxidative metabolism are completely abolished are not al
130 sulin-resistance and decreased mitochondrial oxidative metabolism are early metabolic changes in the
131 sults show that cold-induced NEFA uptake and oxidative metabolism are not defective in type 2 diabete
132 s important for mitochondrial biogenesis and oxidative metabolism are under the control of members of
133 can shift their metabolism toward increased oxidative metabolism as nutrients become depleted and/or
134 ependent reductive carboxylation rather than oxidative metabolism as the major pathway of citrate for
135 lucose also causes a very rapid elevation of oxidative metabolism as was followed by NAD(P)H autofluo
136 ype characterized by elevated glycolysis and oxidative metabolism as well as augmented size, granular
137 as prosthetic group for enzymes involved in oxidative metabolism as well as transcription factors th
139 erse correlation between BACE expression and oxidative metabolism at the first synapse on the olfacto
140 amma treatment resulted in the inhibition of oxidative metabolism at the gene expression and function
141 ycle/DNA metabolic processes and translation/oxidative metabolism at the tissue level, highly reminis
143 the ERRalpha coactivator PGC-1alpha enhanced oxidative metabolism but did not affect tumor growth.
144 mization led to compounds of type 2 with low oxidative metabolism but poor oral bioavailability.
145 tion of fatty acid delivery not only induced oxidative metabolism, but also amplified anaplerosis/cat
146 Ca(2+) flux into the mitochondria helps pace oxidative metabolism, but there is limited in vivo evide
147 channels control global Ca(2+) signaling and oxidative metabolism by inducing Na(+) and Ca(2+) respon
148 for CD8(+) memory T cells, regulated SRC and oxidative metabolism by promoting mitochondrial biogenes
150 Carbon dioxide (CO2 ), a primary product of oxidative metabolism, can be sensed by eukaryotic cells
151 use of increased adipocyte thermogenesis and oxidative metabolism caused by upregulating key enzymes
152 ammatory genes (Mrc1, Tgfb1, Il10, Mgl2) and oxidative metabolism, characteristic of M2 macrophages.
153 ch in turn were used to calculate changes in oxidative metabolism (CMR(O2)) with calibrated fMRI.
154 We conclude that succinate can improve glial oxidative metabolism, consistent our previous findings i
157 These results suggest that stimulants of oxidative metabolism could have therapeutic potential in
158 KCl) and preventing O2-induced increases in oxidative metabolism, cytosolic calcium, and ductal smoo
159 at 7% for 2 weeks, results in inhibition of oxidative metabolism, decreased reactive oxygen species
161 Here, we propose that the normal decline in oxidative metabolism during aging constitutes an early a
162 nd inflammation are associated with elevated oxidative metabolism during an obesogenic diet, and this
166 beta-Klotho pathway orchestrates a switch to oxidative metabolism during fasting and starvation and h
167 es that promote mitochondrial biogenesis and oxidative metabolism during terminal erythroid maturatio
168 interaction between insulin sensitivity and oxidative metabolism during the course of metabolic dise
169 f particular note, the major entry points to oxidative metabolism (eg, pyruvate dehydrogenase complex
171 ative species (ROS) oxidation, extracellular oxidative metabolism (EXOMET), and inorganic chemical re
177 o primed pluripotency by directly repressing oxidative metabolism genes and metabolic intermediates i
179 have revealed that the metabolic pathways of oxidative metabolism, glycolysis, and glutaminolysis pre
180 r repression of inflammation, maintenance of oxidative metabolism, IL-4-mediated induction of alterna
182 roves exercise endurance and skeletal-muscle oxidative metabolism in animals and may enhance vascular
184 , we demonstrated cold-induced activation of oxidative metabolism in BAT, but not in adjoining skelet
185 ATM and p53 in the control of glycolysis and oxidative metabolism in cancer, but their involvement in
186 d increased glucose consumption with reduced oxidative metabolism in cell culture and increased respi
193 ed the AMP-to-ATP ratio, thereby stimulating oxidative metabolism in liver and adipose tissue via AMP
194 udy describes the cerebral oxidative and non-oxidative metabolism in man during a prolonged apnoea (r
195 he ICC lineage and ICC dependence on glucose oxidative metabolism in mice with disruption of the succ
197 pecifies slow twitch fibers, suggesting that oxidative metabolism in muscle is selectively controlled
198 own to control processes related to iron and oxidative metabolism in organisms from bacteria to human
199 RC1 activity and dysregulated glycolytic and oxidative metabolism in response to IL-15 stimulation.
200 on of PGC-1alpha/PPAR-alpha target genes and oxidative metabolism in response to increased ATGL-media
201 a class II-selective HDAC inhibitor enhanced oxidative metabolism in skeletal muscle and adipose tiss
206 ions indicate that astrocytes exhibit robust oxidative metabolism in the intact adult brain and sugge
209 cells, demonstrated increased mitochondrial oxidative metabolism in the presence of exogenous FFAs;
211 that ectopic expression of ERRgamma enhanced oxidative metabolism in vitro and inhibited the growth o
216 activity-dependent NADH transients, neuronal oxidative metabolism increased first upon activation wit
218 in the a-wave of the ERG and changes in rod oxidative metabolism, indicating that these two function
220 As a consequence, in brain tissue where oxidative metabolism is disturbed, brain glucose concent
222 re indicates that mitochondrial capacity for oxidative metabolism is lower in human obesity and type
226 commensurate with the dependence of cells on oxidative metabolism, is more frequent than mitophagy an
227 er regulator of mitochondrial biogenesis and oxidative metabolism, lipogenesis, and triglyceride (TG)
228 ycolytic metabolism to fatty acid and ketone oxidative metabolism may modulate metabolism, signal tra
230 ic molecule that is important for oxygen and oxidative metabolism, most notably as the prosthetic gro
231 ates that reprogramming from a glycolytic to oxidative metabolism occurs during cellular differentiat
232 reactions (ADRs), including hepatotoxicity; oxidative metabolism of 1 has been implicated in the pat
234 2B6 is a polymorphic enzyme involved in the oxidative metabolism of a number of clinically relevant
236 nt cytosolic phospholipase A2 activation and oxidative metabolism of arachidonic acid also contribute
238 s) are the principal enzymes involved in the oxidative metabolism of drugs and other xenobiotics.
241 Recently, the generation of H(2)O(2) by oxidative metabolism of estrogens and other aromatic ste
244 rmally functioning tumour cell mitochondria, oxidative metabolism of glucose- and glutamine-derived c
248 n for its inhibitory action, emphasizing the oxidative metabolism of NAEs as an important feature of
249 uconeogenesis; glucose repressed) during the oxidative metabolism of organic acids, evolved to become
251 or-activated receptor-alpha, and products of oxidative metabolism of polyunsaturated fatty acids via
255 gation of arachidonic acid to glycine and by oxidative metabolism of the endocannabinoid anandamide.
257 tical role in the repair of bases damaged by oxidative metabolism or alkylating agents, such as those
258 sociated with replication, transcription, or oxidative metabolism; other direct sources of endogenous
259 ted the M2 hallmark Ym-1 and genes promoting oxidative metabolism (PGC-1alpha) and adipogenesis (MMP-
260 Together these results indicate that DHEA oxidative metabolism produces potent novel molecules wit
261 ness associated, but upregulated activation, oxidative metabolism, protein synthesis, and lineage ass
263 igated as an alternative approach to address oxidative metabolism, reduce lipophilicity, and improve
264 myotube mRNA expression of genes involved in oxidative metabolism, regardless of the donor and degree
267 hat alterations in cancer cell mitochondrial oxidative metabolism resulting in increased levels of O2
268 in the tumor microenvironment repress T cell oxidative metabolism, resulting in effector cells with m
269 oxygen species (ROS), the toxic products of oxidative metabolism seen as culprits in aging, neurodeg
271 drug that we have recently shown to silence oxidative metabolism, suppresses apoptotic cell death in
272 perfusion (increased anaerobic and decreased oxidative metabolism) that then normalize over the follo
274 , our data link Salmonella genes controlling oxidative metabolism to inflammasome activation and sugg
275 iosis, triggered a switch in host cells from oxidative metabolism to lactate fermentation, increasing
276 ates protein substrates involved in cellular oxidative metabolism to maintain mitochondrial energy pr
278 D8(+) TRM cells use exogenous FFAs and their oxidative metabolism to persist in tissue and to mediate
279 rt of a cell-adaptive response to high lipid oxidative metabolism to protect lipid droplet storage ag
280 ERMs are polyaromatic phenols susceptible to oxidative metabolism to quinoids, which are proposed to
281 t maturation into adult-like CMs with higher oxidative metabolism, transcriptional signatures closer
282 a key role for SIRT5 in maintaining cardiac oxidative metabolism under pressure overload to ensure s
284 ack of functional hyperemia, measurements of oxidative metabolism via flavoprotein fluorescence sugge
286 c defect at the level of both glycolysis and oxidative metabolism was apparent, which was restored af
287 The increase in DEE associated with BAT oxidative metabolism was highly variable in the high-BAT
291 ion is modulated by neuronal activity and/or oxidative metabolism, we compared BACE expression with c
292 scle contraction, and lipid and carbohydrate oxidative metabolism were also observed in cKO SOL.
294 olism, whereas DLST protein levels and hence oxidative metabolism were partially maintained in microR
295 d in wild-type mice, paralleling a decreased oxidative metabolism, whereas DLST protein levels and he
296 neurons, probably from DNA damage induced by oxidative metabolism, which kills nondividing cells in t
297 o inhibits the expression of genes linked to oxidative metabolism while stimulating the expression of
298 Disruption of complex I assembly reduces oxidative metabolism with concomitant increase in mitoch
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