ライフサイエンスコーパス: oxoacid

1 hiolate of C221 and the keto carbon of the 2-oxoacid.

2 teracts with the C4-methyl of 4(S)-hydroxy-2-oxoacids.

3 s the alpha-amino group of l-Lys to acceptor oxoacids.

4 fatty acid hydroperoxides into aldehydes and oxoacids.

5 Biotransformation of gamma-oxoacid 5, in the culture of Beauveria bassiana AM278 an

6 that is required for aerobic metabolism of 2-oxoacids and for C(1) metabolism.

7 ocess is almost exclusively driven by iodine oxoacids and iodine oxide vapours, with average oxygen-t

8 te and multiple independent innovations of 2-oxoacid-binding basic residues among these superfamilies

9 cted to enable the binding of 4(R)-hydroxy-2-oxoacids by relieving the steric hindrance between the 5

10 tivated receptor-alpha (decreased by 51%), 3-oxoacid CoA transferase (decreased by 67%), and acetyl-C

11 of the key ketolytic enzyme, succinyl-CoA:3-oxoacid CoA transferase (SCOT; encoded by Oxct1), as wel

12 drial enzyme CoA transferase (succinyl-CoA:3-oxoacid CoA transferase, SCOT, encoded by nuclear Oxct1)

13 fied with partial sequence as succinyl-CoA:3-oxoacid CoA-transferase (SCOT; EC ).

14 ses the catalytic activity of succinyl-CoA:3-oxoacid CoA-transferase, and induces aggregation of mito

15 pression of the gene encoding succinyl-CoA:3-oxoacid-CoA transferase, the rate-limiting enzyme for my

16 arate dehydrogenase (OGDH), branched-chain 2-oxoacid dehydrogenase (BCKDH), and pyruvate dehydrogenas

17 enase complex (PDC-E2), the branched chain 2-oxoacid dehydrogenase complex E (BCOADC-E2), and the 2-o

18 is mechanism could be a general feature of 2-oxoacid dehydrogenase complexes because such interfacial

19 her NAD(P)H/NAD(P)(+) ratios, although the 2-oxoacid dehydrogenase complexes produced superoxide/H2O2

20 ase activity data indicate that all of the 2-oxoacid dehydrogenase components are present.

21 catalyzed by the E1 and E2 enzymes of the 2-oxoacid dehydrogenase multienzyme complexes by a previou

22 e for anti-M2 antibodies reacting with the 2-oxoacid-dehydrogenase complex (ODC) also antibodies to t

23 substrates as well as lipoic acid from two 2-oxoacid dehydrogenases and an isolated lipoylated lipoyl

24 hed cofactor essential for the activity of 2-oxoacid dehydrogenases and the glycine cleavage system.

25 e lipoyl domains of the E2 subunits of the 2-oxoacid dehydrogenases of aerobic metabolism.

26 for octanoylation of the E2 components of 2-oxoacid dehydrogenases to provide the substrates of LipA

27 Lipoamidase-mediated inactivation of the 2-oxoacid dehydrogenases was observed both in vivo and in

28 poic acid in the reaction mechanism of the 2-oxoacid dehydrogenases, the identity of the lipoamidase

29 ate salvage, shows no interaction with the 2-oxoacid dehydrogenases.

30 ich are generally the E2 components of the 2-oxoacid dehydrogenases.

31 a-helix type structures of the Fe(II)- and 2-oxoacid-dependent dioxygenases, such as collagen prolyl

32 berate, completing three iterations of the 2-oxoacid elongation pathway.

33 aldococcus jannaschii uses three different 2-oxoacid elongation pathways, which extend the chain leng

34 Like other members of the 2-oxoacid:ferredoxin oxidoreductase family, OOR contains t

35 ly bonded dimers and trimers of the starting oxoacids, many of which are multi-tailed lipids.

36 y, based on microbial lactonization of gamma-oxoacids, naturally occurring opposite isomers of whisky

37 e, and several other amino acids to generate oxoacids or derived products in vitro.

38 t acetone; this simple procedure affords the oxoacid salt in 94% yield.

39 e now available to create chiral 4-hydroxy-2-oxoacid skeletons as synthons for organic reactions.

40 h rates only when oxidizing their specific 2-oxoacid substrates and not in the reverse reaction from

41 s demonstrating differential expression of 3-oxoacid transferase, the key enzyme for ketolytic energy

42 tate aminotransferase [Got2] and hydroxyacid-oxoacid transhydrogenase [Adhfe1]).

43 The alkyl oxoacids under study here can undergo a Norrish Type II

44 of HIF-1 hydroxylation by glucose-derived 2-oxoacids underlies the prominent basal HIF-1 activity co

45 variants are able to synthesize 4-hydroxy-2-oxoacids up to eight carbons in length, which were the o

46 carbon-carbon bond formation of 4-hydroxy-2-oxoacids up to eight carbons in length.

47 proteolysis and sequencing, but the bound 2-oxoacid was released during the protocol.

48 OOR also oxidizes a few other 2-oxoacids (which do not induce OOR) also without any requ