ライフサイエンスコーパス: p75 neurotrophin receptor

1 very similar gamma-secretase cleavage is the p75 neurotrophin receptor.

2 sociate with the intracellular domain of the p75 neurotrophin receptor.

3 he iota PKC.IRAK complex is recruited to the p75 neurotrophin receptor.

4 mechanism, supported by up-regulation of the p75 neurotrophin receptor.

5 the actions of BDNF are mediated through the p75 neurotrophin receptor.

6 so be induced by selective activation of the p75 neurotrophin receptor.

7 uce Schwann cell death via engagement of the p75 neurotrophin receptor.

8 ival or cell death decisions mediated by the p75 neurotrophin receptor.

9 ia a yet undefined mechanism mediated by the p75 neurotrophin receptor.

10 e extracellular neurotrophin binding site of p75 neurotrophin receptor.

11 ransducer for the effects of NGF through the p75 neurotrophin receptor.

12 ergic neurons and terminals that express the p75 neurotrophin receptor.

13 the Fas receptor, the p75 TNF receptor, and p75 neurotrophin receptor.

14 f NGF or by antibodies to either trkB or the p75 neurotrophin receptor.

15 dependent signalling mechanism involving the p75 neurotrophin receptor.

16 n of the kinase-active Trk receptors and the p75 neurotrophin receptor.

17 l-like receptor superfamilies, including the p75 neurotrophin receptor.

18 ng component of this receptor complex is the p75 neurotrophin receptor.

19 Trk receptor tyrosine kinases and the shared p75 neurotrophin receptor.

20 ARMS can physically associate with TrkA and p75 neurotrophin receptors.

21 GF binds to the TrkA tyrosine kinase and the p75 neurotrophin receptor, a member of the tumor necrosi

22 The p75 neurotrophin receptor, a member of the tumor necrosi

23 The p75 neurotrophin receptor, a member of the tumor necrosi

24 Mechanistically, blockade of the p75 neurotrophin receptor abolished BDNF-induced postsyn

25 e studies provide a new reagent for altering p75 neurotrophin receptor actions after injury and sugge

26 t regulated intramembrane proteolysis of the p75 neurotrophin receptor (also known as p75 cleavage).

27 ls via the tyrosine receptor kinase B (TrkB)/p75 neurotrophin receptor and Fyn kinase in transfected

28 First, SC-1 interacts with the p75 neurotrophin receptor and is redistributed from the

29 s were characterized using antibodies to the p75 neurotrophin receptor and trkB receptors.

30 an interact through its TRAF domain with the p75 neurotrophin receptor and weakly with the lymphotoxi

31 factor induced apoptosis in cells expressing p75 neurotrophin receptor, and enhances neurite outgrowt

32 In adulthood, p75 neurotrophin receptor becomes down-regulated and pro

33 educes binding of pro-nerve growth factor to p75 neurotrophin receptor, blocks pro-nerve growth facto

34 erve growth factor (NGF) in complex with the p75 neurotrophin receptor but is distinct from that of m

35 t dependence, these neurons express trkB and p75 neurotrophin receptor but not trkA or trkC mRNAs.

36 ng to mature oligodendrocytes expressing the p75 neurotrophin receptor, but not trkA, resulted in a s

37 ta, osteoprotegerin, FOXC2 and FOXF2, BMP-2, p75 neurotrophin receptor, caspase-11, guanylate-binding

38 are closely related to NRAGE, which mediates p75 neurotrophin receptor-dependent apoptosis, and necdi

39 This consolidates a potential role of the p75 neurotrophin receptor during stress and inflammatory

40 e-bolus propofol applications at the peak of p75 neurotrophin receptor expression after experimental

41 cause is the lack of NO, which up-regulated p75 neurotrophin receptor expression, a receptor require

42 ate developmental-like programs and increase p75 neurotrophin receptor expression, probably to foster

43 DNF-tyrosine-related kinase B (TrkB) p75NTR (p75 neurotrophin receptor) facilitates stabilization of

44 ed a cDNA for the LacZ reporter or the human p75 neurotrophin receptor, for which species-specific an

45 combines the 192 monoclonal antibody to the p75 neurotrophin receptor found on terminals and cell bo

46 The p75 neurotrophin receptor has been implicated in neurotr

47 n contrast, optical density for low-affinity p75 neurotrophin receptor immunoreactivity in the VLDB d

48 terferes with oligomerization of full-length p75 neurotrophin receptor in a dose-dependent manner.

49 1 receptor-associated kinase (IRAK) with the p75 neurotrophin receptor in PC12 cells.

50 rescence for either ChAT or the low-affinity p75 neurotrophin receptor in the nucleus basalis Meynert

51 arget-derived NGF promotes expression of the p75 neurotrophin receptor, in turn causing a reduction i

52 Schwann cell factor 1 (SC1), a p75 neurotrophin receptor-interacting protein, is a memb

53 p75 neurotrophin receptor is highly expressed during ear

54 The p75 neurotrophin receptor is important in multiple physi

55 a valine residue at position 264 in the rat p75 neurotrophin receptor is necessary for the ability o

56 Previously, we have shown that p75 neurotrophin receptor is required for glioma invasio

57 Activation of the p75 neurotrophin receptor leads to a variety of effects

58 itory signals through the same Nogo receptor/p75 neurotrophin receptor/LINGO-1 (NgR1/p75/LINGO-1) com

59 neurotrophic factor ratio, which aggravates p75 neurotrophin receptor-mediated cell death.

60 BMP9 induced the p75 neurotrophin receptor (NGFR), a marker of BFCN, and

61 enesis and recent evidence suggests that the p75 neurotrophin receptor (NTR) contributes significantl

62 sal forebrain neurons immunoreactive for the P75 neurotrophin receptor (NTR) in male and female Sprag

63 We show that the p75 neurotrophin receptor (NTR) serves this role in reti

64 tors while down-regulating the expression of p75 neurotrophin receptor (NTR), phospho-JNK, and Bcl-2-

65 -hybrid library with the death domain of the p75 neurotrophin receptor (NTR), we identified the Sall2

66 al neurons mediated to a great extent by the p75 neurotrophin receptor (NTR).

67 ) migration and promotes myelination via the p75 neurotrophin receptor (NTR).

68 BDNF acts via TrkB and p75 neurotrophin receptors (NTR), and restoring its sign

69 ived compound, EVT901, which interferes with p75 neurotrophin receptor oligomerization through direct

70 ProNGF activates p75 neurotrophin receptor (p75(NTR)) and sortilin recept

71 that TAp73 is a transcriptional activator of p75 neurotrophin receptor (p75(NTR)) and that p75(NTR) m

72 ctor (BDNF) activate two distinct receptors: p75 neurotrophin receptor (p75(NTR)) and TrkB.

73 The p75 neurotrophin receptor (p75(NTR)) belongs to the tumo

74 eurotrophic factor (BDNF)-activated TrkB and p75 neurotrophin receptor (p75(NTR)) by disrupting the e

75 al role in Alzheimer's disease (AD), and the p75 neurotrophin receptor (p75(NTR)) has been implicated

76 The role of the p75 neurotrophin receptor (p75(NTR)) in adult cholinergi

77 Expression of the p75 neurotrophin receptor (p75(NTR)) in primary melanoma

78 Here we report that the p75 neurotrophin receptor (p75(NTR)) is a co-receptor of

79 We show that cleaved p75 neurotrophin receptor (p75(NTR)) is a component of t

80 The p75 neurotrophin receptor (p75(NTR)) is a member of the

81 The p75 neurotrophin receptor (p75(NTR)) is a multifunctiona

82 Here we show that the p75 neurotrophin receptor (p75(NTR)) is a regulator of g

83 f nerve growth factor (NGF) signaling by the p75 neurotrophin receptor (p75(NTR)) is critical for neu

84 e of distinct structural determinants in the p75 neurotrophin receptor (p75(NTR)) is crucial for the

85 The p75 neurotrophin receptor (p75(NTR)) is expressed on man

86 The p75 neurotrophin receptor (p75(NTR)) is highly expressed

87 The p75 neurotrophin receptor (p75(NTR)) mediates neuronal d

88 The p75 neurotrophin receptor (p75(NTR)) mediates the death

89 can be initiated by activation of either the p75 neurotrophin receptor (p75(NTR)) or the more selecti

90 The p75 neurotrophin receptor (p75(NTR)) regulates a wide ra

91 Here, we show that p75 neurotrophin receptor (p75(NTR)) undergoes hypoxia-i

92 neuron loss, distal axonal degeneration and p75 neurotrophin receptor (p75(NTR)) upregulation in the

93 structures of complexes formed by the DD of p75 neurotrophin receptor (p75(NTR)) with RhoGDI, for ac

94 s the de novo expression of the low-affinity p75 neurotrophin receptor (p75(NTR)), a gene that plays

95 The p75 neurotrophin receptor (p75(NTR)), a member of the tu

96 Here, we report that the p75 neurotrophin receptor (p75(NTR)), a TNF receptor sup

97 examined the expression of the low affinity p75 neurotrophin receptor (p75(NTR)), an excellent marke

98 c efferents, identified by the low-affinity, p75 neurotrophin receptor (p75(NTR)), with interneurons

99 This produced a substantial loss of both p75 neurotrophin receptor (p75(NTR))-positive and cholin

100 proNGF, is a potent apoptotic ligand for the p75 neurotrophin receptor (p75(NTR))-sortilin complex.

101 erated synapse elimination via activation of p75 neurotrophin receptor (p75(NTR)).

102 ent prevented by blocking antibodies against p75 neurotrophin receptor (p75(NTR)).

103 engaging in a complex with sortilin and the p75 neurotrophin receptor (p75(NTR)).

104 oting signals are generated by activation of p75 neurotrophin receptors (p75(NTR)).

105 eled for choline acetyltransferase (ChAT) or p75-neurotrophin receptor (p75(NTR) ).

106 r (EMMPRIN), with the cognate apical marker, p75-neurotrophin receptor (p75-NTR).

107 Proneurotrophins bind with high affinity to p75 neurotrophin receptor (p75NTR) and lack the capacity

108 types and mediates its effects by binding to p75 neurotrophin receptor (p75NTR) and sortilin.

109 tment with antisense oligonucleotides to the p75 neurotrophin receptor (p75ntr) decreased basal survi

110 pment of the sympathetic nervous system, the p75 neurotrophin receptor (p75NTR) has a dual function:

111 tate gyrus, the distribution of low-affinity p75 neurotrophin receptor (p75NTR) immunoreactivity (IR)

112 septum, choline acetyltransferase (ChAT) and p75 neurotrophin receptor (p75NTR) immunoreactivity, and

113 Here, we investigate the involvement of p75 neurotrophin receptor (p75NTR) in Abeta-treated huma

114 We investigated the role of the p75 neurotrophin receptor (p75NTR) in mediating neurotro

115 To determine the role of the p75 neurotrophin receptor (p75NTR) in sympathetic neuron

116 Our goal was to determine the role of the p75 neurotrophin receptor (p75NTR) in the loss of islet

117 ad, myelin-associated glycoprotein recruited p75 neurotrophin receptor (p75NTR) into a complex with L

118 Previously, we have shown that p75 neurotrophin receptor (p75NTR) is a novel mediator o

119 The p75 neurotrophin receptor (p75NTR) is a proximate cell m

120 Emerging evidence suggests that the p75 neurotrophin receptor (p75NTR) mediates cell death;

121 Plasticity was rescued by inhibiting p75 neurotrophin receptor (p75NTR) signaling or its down

122 Here we show that the p75 neurotrophin receptor (p75NTR) undergoes presenilin-

123 nizes trkA, trkB, and trkC) and low-affinity p75 neurotrophin receptor (p75NTR) was examined in the h

124 They express the p75 neurotrophin receptor (p75NTR), which is known to si

125 ohol drinking produces a mobilization of DLS p75 neurotrophin receptor (p75NTR), whose activities opp

126 lls (SCs) and an increased expression of the p75 neurotrophin receptor (p75NTR).

127 ro-NGF increased LDLR expression through the p75 neurotrophin receptor (p75NTR).

128 mbers in G1H mice that re-express the common p75 neurotrophin receptor (p75NTR).

129 mice with and without the expression of the p75 neurotrophin receptor (p75NTR).

130 s, the TrkA tyrosine kinase receptor and the p75 neurotrophin receptor (p75NTR).

131 that was triggered by overexpression of the p75 neurotrophin receptor (p75NTR).

132 mesenchymal cells expressing both desmin and p75 neurotrophin receptor (p75NTR): HSCs in the liver pa

133 or the pro-brain-derived neurotrophic factor-p75 neurotrophin receptor pathway.

134 the same set of transcription factors from a p75 neurotrophin receptor peptide (p75NTRp)-tagged adeno

135 p75 neurotrophin receptor plays an important role in the

136 NF appear to be mediated by the low-affinity p75 neurotrophin receptor, rather than a trk receptor.

137 The p75 neurotrophin receptor regulates neuronal survival, p

138 Furthermore, the p75 neurotrophin receptor restricts PSD formation, sugge

139 that of NRAGE, a MAGE protein that mediates p75 neurotrophin receptor signaling and neuronal apoptos

140 e results revealed new functions for proBDNF-p75 neurotrophin receptor signaling pathway in the contr

141 by unbalancing neurotrophin homeostasis via p75 neurotrophin receptor signaling.

142 ermore, we demonstrate that EVT901 abrogates p75 neurotrophin receptor signalling by other ligands, s

143 rauma and other neurological disorders where p75 neurotrophin receptor signalling is affected.

144 and gp120 were blocked by inhibitors of the p75 neurotrophin receptor, suggesting that proBDNF and g

145 c inhibition of the cell death domain of the p75 neurotrophin receptor (TAT-Pep5) and in mice lacking

146 rve growth factor (NGF) and the low-affinity p75 neurotrophin receptor, their sensory nerve fibers ex

147 ecule, nicotinic acetylcholine receptor, and p75 neurotrophin receptor), thus demonstrating that pseu

148 t Par-3 directly associates and recruits the p75 neurotrophin receptor to the axon-glial junction, fo

149 s ability to redirect the apically localized P75 neurotrophin receptor to the basolateral membrane do

150 ding assays with cysteine-rich domains-fused p75 neurotrophin receptor, we confirmed that EVT901 inte

151 he p75 TNF receptor, the Fas antigen, or the p75 neurotrophin receptor, which are other members of th