ライフサイエンスコーパス: pack against

1 of helical hairpins in which three C helices pack against a central coiled coil.

2 domain III (DIII) and the juxtamembrane stem pack against a central core trimer.

3 At the other end, two Cand1 HEAT repeats pack against a conserved Cul1 surface cleft and bury a C

4 n III (DIII) and the stem region (DIII-stem) pack against a core trimer composed of E1 domains I and

5 n acidic helix joining the chromodomains can pack against a DNA-binding surface of the ATPase motor.

6 contains two antiparallel alpha-helices that pack against a four-stranded beta-sheet.

7 es is helical and uses the analogous face to pack against a groove formed by an N-terminal coiled-coi

8 damentally different from the way the chains pack against a large protein surface.

9 ing barriers as well as nucleosomes actively packed against a barrier.

10 haped form with a glutamine-rich alpha helix packed against a beta-sheet framework.

11 The chromodomain fold - three beta strands packed against a C-terminal alpha helix - mediates prote

12 -Ca(2+)-binding helix-loop-helix (HLH) motif packed against a canonical Ca(2+)-binding EF-hand motif.

13 ree-stranded antiparallel beta-sheet that is packed against a carboxy-terminal alpha helix.

14 so-called "hot dog" fold with a large helix packed against a five-stranded anti-parallel beta-sheet.

15 igonucleotide binding fold, with two helices packed against a five-stranded beta-barrel.

16 positioning, the localization of nucleosomes packed against a fixed barrier, is conjectured to explai

17 d, consisting of a three-stranded beta-sheet packed against a four-stranded beta-sheet.

18 roteins favor RPGs with three local residues packed against a non-local residue.

19 ring a strong driving force for right-handed packing against a neighboring helix.

20 zed both by interactions with the DNA and by packing against a region of the core DBD normally reserv

21 Pro(20) induces a bend in TMH-1, which then packs against a more straightened TMH-2.

22 he amino-terminal caspase recruitment domain packs against a three-layered alpha/beta fold, a short h

23 which three carboxyl-terminal outer helices pack against an inner trimeric coiled coil.

24 core folding with a four-stranded beta-sheet packed against an alpha-helix, seen in the well-studied

25 e antiparallel carboxyl-terminal helices are packed against an amino-terminal trimeric coiled coil.

26 This patch is tightly packed against an underlying sandwich of chloroplast mem

27 25 characterize a hydrophobic cluster, which packs against an irregular beta-sheet, whereas residues

28 Lys213 packs against an otherwise exposed aromatic residue and

29 are exposed to solvent while the first seven pack against and form part of the N-terminal domain, and

30 The N-loop (residues 9-16) is packed against both the sheet and the helix with the two

31 The coiled coil packs against both Fis1 and the second helix of the Mdv1

32 re reveals that the highly conserved Phe-216 packs against conserved Gln-226 residues present on the

33 al helix from Wza, the GfcC C-terminal helix packs against D3.

34 Subsequently, these pairs pack against each other and onto the alpha-helical regio

35 17 and Leu34 side chains of the same peptide pack against each other at the beta-sheet interface with

36 ), the H-loops of the two catalytic subunits pack against each other at the dimer interface, necessit

37 drophobic heptad repeats and are designed to pack against each other in a "knobs-into-holes" manner.

38 eets (five and four beta-strands each), that pack against each other in a parallel beta-sandwich.

39 ructures, the OB folds of the two components pack against each other through interactions between two

40 nformation wherein the linker and N3 domains pack against each other via a hydrophobic interface.

41 Rpn13's ubiquitin- and Uch37-binding domains pack against each other when it is not incorporated into

42 The two B-box domains pack against each other with the interface formed by res

43 atic changes in the way in which nucleosomes pack against each other within the crystal lattice.

44 -length hexameric forms, these two loops are packed against each other and are stabilized by intimate

45 that the conserved hydrophobic residues are packed against each other in the protein core and that H

46 ntiparallel beta-sheets with 7 main strands, packing against each other, forming a beta-sandwich.

47 twisted and tilted out of the base stack to pack against finger 1 and the tip of finger 2.

48 In the sequestered form, the U37 base packs against G36, and its 2'-hydroxyl group forms a wat

49 we show that in Abeta amyloid fibrils, Met35 packs against Gly33 in the C-terminus of Abeta40 and aga

50 hat the methyl groups of Val80 and Val84 are packed against Gly79 and Gly83, respectively.

51 ce, while the alpha1-alpha2 loop and helix 2 pack against helices 3 and 5 from the opposing monomer.

52 hort fifth helix (helix A') which is closely packed against helix D in an approximately parallel fash

53 Leu56 and Tyr57 of the loop pack against hydrophobic residues from two separate subu

54 ic Tyr describes an all-helix subdomain that packs against interfacial helices, eliminating the four-

55 points away from the beta-barrel instead of packing against it.

56 nd alpha-helix 3, which is partially formed, packs against it.

57 at the subunit interface where helix alpha6 packs against its symmetric partner, helix alpha6'.

58 ARTD15 features an alpha-helical domain that packs against its transferase domain without making dire

59 lated motif in which the alphaCT alpha-helix packs against L1 beta-strands 2 and 3.

60 (6) It is almost a rule that TM helices pack against neighbors in the sequence.

61 by complementarities among side chains that pack against one another at the helix-helix interface.

62 mer in which 2 five-stranded beta-sheets are packed against one another and flanked by alpha-helices

63 the active site loop and supporting loop are packed against one another and stabilized by monomer-mon

64 of five and three antiparallel beta-strands packed against one another.

65 parallel sheet with a two-alpha-helix bundle packed against one face of the sheet.

66 adopts a structure with three alpha-helices packed against one side of a three-stranded antiparallel

67 tiparallel beta-sheet with two alpha-helices packed against one side of this sheet.

68 As in other chemokines, the alpha-helix packs against one face of the beta-sheet.

69 The side chains of Lys331 and Pro417 pack against opposite faces of the guanine nucleotide ba

70 sts of buried residues with side-chains that pack against other CDR residues and apparently act as sc

71 ix (139-143) in the C-terminal domain of PI3 packs against residues 289-295 that form a loop in p. pe

72 nesis screen aimed at determining whether S4 packs against S5 of the pore domain.

73 th three parallel/antiparallel alpha-helices packed against six parallel/antiparallel beta-strands th

74 In our model, Gly residues in GXXXG motifs pack against small Ala or Val side chains to generate th

75 Bulky residues Ile 177 and Ile 181 pack against small residues of the opposite monomer, and

76 re limited to the outer beta-strand F, which packs against strand F' in the tetramer, while the B, C,

77 erminal half of alphaM1 is alpha-helical and packs against structural element(s) that contribute to t

78 arboxy-terminal beta-hairpin and alpha-helix pack against switch II.

79 n which the alpha-helices of the AP2 domains pack against the beta-sheets of the dimer mates.

80 pectedly, two mobile loops that rearrange to pack against the bound NO in NP4-NO, also rearrange in t

81 he N-terminal substructure of one monomer to pack against the C-terminal substructure of a second mon

82 n-like domain III (DIII) and the stem region pack against the central core of the trimer.

83 surrounded by three C-terminal regions that pack against the coiled coil in an oblique antiparallel

84 ions between the second two helices and also pack against the conserved alanines that interdigitate b

85 sites, respectively, on nucleosomal DNA and pack against the DNA-binding domain on DNA exiting the n

86 nal inhibitory regions have been proposed to pack against the ETS domain and form an autoinhibitory m

87 rd complementarity-determining region (CDR3) pack against the framework and stabilize the global V(H)

88 3 reside near the boundaries of the loop and pack against the framework to form a small hydrophobic c

89 erminus of the first helix and L237 and I241 pack against the helices, perhaps to stabilize alternati

90 The two tryptophan residues were found to pack against the lysine side chain forming an aromatic p

91 The side chains of Ile14 and Ile94, which pack against the nicotinamide and pterin rings of the co

92 e outer ring of transmembrane helices do not pack against the pore-forming helices, creating an appar

93 que combination of hydrophobic residues that pack against the protein core.

94 lt in this structure, and they were found to pack against the putative hinge region implicated in the

95 ophobic environment, but TM7 does not stably pack against the remaining helices.

96 core of the free protein but rotates out to pack against the sugar-phosphate backbone of the DNA in

97 , we propose that in the OT complex Stt3p is packed against the alpha 2-helix of Ost4p by using a "ri

98 with the predominant state comprising the OH packed against the BARAD, contrary to expectations based

99 clusive states: either as part of the CCD or packed against the C-terminal beta-alpha repeated, autop

100 domain, with the opposite end of the channel packed against the domain-swapped subunit.

101 F); N1 of Pex1 is mobile, but the others are packed against the double ring.

102 Also, a hydrophobic Met-16 side chain is packed against the edge of the ring of Tyr-9.

103 ged in a closed configuration with domain II packed against the G domain in the vicinity of the Switc

104 YS(1252) motif adopts a conformation tightly packed against the kinase C-lobe when Ser-1248 is in the

105 lated nanoparticles are isotachophoretically packed against the migrating depletion front.

106 Microcolumns of hydrophobic beads packed against the polymethacrylate plugs were utilized

107 n active conformation, with helices 1 and 12 packed against the predicted alpha-helical bundle, in th

108 ion, the unique double PXXP motif is tightly packed against the rest of the protein, rendering this p

109 hat this region is highly mobile and loosely packed against the rest of the protein.

110 y for clathrin binding, is transient and not packed against the rest of the structure.

111 e consists of two antiparallel alpha-helices packed against the same side of a five-stranded beta-she

112 andwich of two nearly parallel alpha helices packed against the same side of a four-stranded beta she

113 ing topology with two parallel alpha-helices packed against the same side of a four-stranded beta-she

114 helical conformation upon complex formation, packing against the 'ABED' sheet of TrkA-d5.

115 a 60 degrees angle above the haem plane and packing against the central I helix with the 3beta-OH in

116 ed binding to GlcNAc may result from Ile-313 packing against the N-acetyl group.

117 per surface of Siah1, with two extended legs packing against the sides of Siah1 by means of a consens

118 to the N-terminus forming an Omega-loop and packing against the structured core of the protein, not

119 tor that present hydrophobic side chains for packing against the surface of haemoglobin.

120 a unique N-terminal extension sequence that packs against the 3-box in a hydrophobic groove centrall

121 We found that one face of the nSH2 domain packs against the 581-593 region of the iSH2 domain.

122 unphosphorylated CheB, the N-terminal domain packs against the active site of the C-terminal domain a

123 Leucine (L) 124 of one subunit packs against the adenine ring of cAMP bound to the oppo

124 A8 packs against the amino-terminal knuckle and forms a hyd

125 to the major groove of the RNA stem and also packs against the amino-terminal zinc knuckle.

126 minal extensions form a small subdomain that packs against the beta-sandwich and mediates dimerizatio

127 unit; presently, the structural element that packs against the buried face of the helix remains unide

128 trimeric hairpin in which domain III (DIII) packs against the central trimer.

129 d within but not between Eph RTK subclasses, packs against the concave beta-sandwich surface near pos

130 rom the surface of insulin, whereas Phe(B24) packs against the core.

131 ch regulates ATP hydrolysis and degradation, packs against the D1 ring of Cdc48 in a coplanar fashion

132 Ftz-F1 domain folds into a novel helix that packs against the DBD but does not contact DNA.

133 ee pentamers, on a conserved loop (G2H) that packs against the dual interpentamer Ca(2+)-binding site

134 lix in the C-terminal inhibitory domain that packs against the ETS domain and perturbs the conformati

135 e tandem N-terminal helical solenoid tightly packs against the FAT and kinase domains.

136 esidue 65 did affect the way the polypeptide packs against the methionine-ligated side of the heme.

137 rting a model in which the S4 voltage sensor packs against the pore domain in the hyperpolarized, or

138 the N-terminal tail forms a 3(10) helix that packs against the proximal zinc knuckle and interacts wi

139 ing Ile303, a large hydrophobic residue that packs against the ring meta-C(H) group.

140 the ligand-occupied structure, the 4H domain packs against the SH2 domain and completes its phosphoty

141 The third dimer packs against the side of a face-face interface in a tig

142 a long C-terminal arm within the ectodomain packs against this coil in an antiparallel manner.

143 The ZipA domain is a six-stranded beta-sheet packed against three alpha-helices and contains the spli

144 sting of a three-stranded beta sheet that is packed against three alpha-helices.

145 3) ORG27569 packs against TMH6, sterically hindering movements of th

146 beta-sheet (residue 25-29, 39-44, and 48-52) packed against two C-terminal antiparallel alpha-helices

147 flat, six-stranded anti-parallel beta sheet packed against two helices.