ライフサイエンスコーパス: packaging

1 ation of the duplex into a procapsid (genome packaging).

2 ment compliance aids and original medication packaging).

3 not the Vpx-SAMHD1 interaction or Vpx virion packaging.

4 ablate putative PSs may not see an effect on packaging.

5 ng of influenza vRNA architecture and genome packaging.

6 ons resulting in a near-complete loss of RNA packaging.

7 te the gRNA condensation required for genome packaging.

8 segment population available in the cell for packaging.

9 ibility required for capsid assembly and DNA packaging.

10 ch matures the genome end in preparation for packaging.

11 be integrated with large-area adhesives for packaging.

12 ed to the surface of the compartment for DNA packaging.

13 ed for both nucleocapsid assembly and genome packaging.

14 ence likely plays an indirect role in genome packaging.

15 ce free DNA ends, such as DNA replication or packaging.

16 g it unable to tolerate the stress of genome packaging.

17 be a static channel at the late stage of DNA packaging.

18 uces DNA compression and rotation during DNA packaging.

19 d medication was identical in appearance and packaging.

20 d-to-end concatemers of the phage genome for packaging.

21 alue areas and in basic applications such as packaging.

22 ries following strict guidelines for complex packaging.

23 tromechanical systems, and electronic device packaging.

24 assembly although it is essential for pgRNA packaging.

25 teins were also identified as candidates for packaging.

26 ) from smoked sausages by migration into the packaging.

27 distribution, and/or RNA binding and virion packaging.

28 ystem compatible with adeno-associated viral packaging.

29 plex chemical composition while still in its packaging.

30 at both initiation and completion of genome packaging.

31 nce in the monitoring of modified atmosphere packaging.

32 were observed (1385 from original medication packaging, 1067 from multi-compartment compliance aids).

33 Packaging a dimeric genome allows the recovery of geneti

34 is accompanied by 22 ready to use BIDS Apps, packaging a diverse set of commonly used neuroimaging al

35 Packaging and capsid assembly in RNA viruses can involve

36 complex with diverse functions in chromatin packaging and chromosome condensation and segregation.

37 The current consensus in packaging and delivering CpGs in VLP-based vaccines is t

38 We describe here a one pot RNA production, packaging and delivery system based on bacteriophage Qbe

39 protein as well as DNA, suggesting that DNA packaging and expulsion of the scaffolding protein are c

40 re homes (five only used original medication packaging and five used both multi-compartment complianc

41 lications, such as the development of active packaging and functional foods.

42 essential for genome stabilization after DNA packaging and implicated in Gram-negative cell envelope

43 istration errors between original medication packaging and multi-compartment compliance aids in care

44 Compare the effect of original medication packaging and multi-compartment compliance aids on medic

45 ation error rate between original medication packaging and multi-compartment compliance aids supports

46 .9, p=0.03), and between original medication packaging and multi-compartment compliance aids within c

47 of predicted RNA structures in picornavirus packaging and offers a readily transferable methodology

48 genomic DNA into unit lengths during genome packaging and particle assembly.

49 ein assemblies can acquire virus-like genome packaging and protection.

50 acellular pathogen engages host pathways for packaging and release.

51 Because of its dense packaging and repetitive DNA sequence, heterochromatin i

52 fic) laboratory for core activities, such as packaging and shipping, direct microscopic examination,

53 are critically influenced by the nucleosome packaging and the chromatin architecture surrounding the

54 ntion were the storage duration, the type of packaging and the temperature.

55 EVs are essential for the packaging and transport of many cell-fate proteins durin

56 important for efforts to improve AAV genome packaging and will also inform the engineering of AAV ca

57 sorting process that regulates segregation, packaging, and budding of peroxisomal importomer subcomp

58 teins involved in gene silencing, chromosome packaging, and chromosome segregation.

59 RNA processing, splicing, export, stability, packaging, and degradation.

60 A simplified formulation, packaging, and delivery method to treat PSBI in low-reso

61 mation on archaeal virion structures, genome packaging, and determinants of temperature resistance.

62 material, some with a coating of REO (active packaging, AP), and some without REO (non active packagi

63 icles in which expulsion of scaffold and DNA packaging are incomplete.

64 ration was higher under air than in a vacuum packaging atmosphere.

65 rtal vertex' and consists of a portal, a DNA packaging ATPase and other components.

66 rotein IVa2 is presumed to function as a DNA packaging ATPase.

67 the complete atomic model of the headful DNA-packaging bacteriophage Sf6 at 2.9 A resolution determin

68 chlorotic mottle virus (CCMV) is capable of packaging both purified single-stranded RNA molecules of

69 from sausages into low density polyethylene packaging bulk and the measure of decrease can be predic

70 ls now include the impacts of processing and packaging but are far from comprehensive.

71 pressure that is generated during DNA genome packaging by locally reinforcing the mechanical sturdine

72 ive tools in gene therapy, but their limited packaging capacity can be restrictive.

73 rly useful for in vivo applications when the packaging capacity of recombinant adeno-associated virus

74 ny functional motifs as possible, within the packaging capacity of the viral vector.

75 Acidic clusters act as sorting signals for packaging cargo into clathrin-coated vesicles (CCVs), an

76 may be useful for generating recombinant AAV-packaging cell lines and the directed evolution of AAV c

77 By using PLA packaging combination it was possible to maintain an opt

78 sDNA bacteriophages have revealed that a DNA packaging complex assembles at a special vertex called t

79 ect of REO combined with modified atmosphere packaging conditions (MAP), in our case, aerobic, vacuum

80 colourimetric analyses showed that the best packaging conditions were high-O2 atmosphere in combinat

81 es, mycotoxins, process-induced toxicants or packaging contaminants, were carefully chosen for their

82 The efficiency of initiation of packaging correlates strongly with motor velocity.

83 scale viral channel at the late stage of DNA packaging could be a consequence of Brownian movement of

84 Packaging CpGs into nanoparticles, in particular into vi

85 s, we have developed a new formulation by co-packaging DAC and ATO into alendronate-conjugated bone-t

86 onformational parameters based on nucleosome packaging data are most similar to the experimental meas

87 s of the capsid contributed to producing the packaging defect and highlight a tight connection betwee

88 ifferences between wild-type (wt) AAV2 and a packaging deficient variant, AAV2-R432A, were examined u

89 Previous studies found that tRNA(Lys3) packaging depends on interactions between LysRS and HIV-

90 Therefore, the strategy of packaging dimeric RNA affects viral replication and vira

91 on of the viral genome for initiation of DNA packaging during virus assembly.

92 ism by which HIV-1 achieves efficient genome packaging during virus assembly.IMPORTANCE Retrovirus as

93 only resulted in a moderate decrease of RNA packaging efficiencies.

94 ity of mutations are neutral with respect to packaging efficiency with a small number of mutations re

95 ion between the entire capsid in maintaining packaging efficiency.

96 ined via a road-map involving selected "food-packaging-environment" system descriptors.

97 as tissue scaffold templates, drug delivery, packaging, etc., due to their inherent sustainability, b

98 present bio-elastomers can be used in active packaging for a variety of pharmaceutical, medical, and

99 pouches containing N2 are the most suitable packaging for preserving the key aroma compound 2-acetyl

100 nce aids (for most medications) and original packaging (for medications with stability issues) is sup

101 gard to thermoformed packaging (TF) and flow-packaging (FP).

102 tion error rates between original medication packaging (from original medication packaging-only care

103 t positions 5, 7, 10 and 11 are defective in packaging full-length STMV, but can package a truncated

104 ect of these nt-pairings on dimerization and packaging has been documented their effect on authentic

105 post-translational modifications to the DNA packaging histones on the normal genome and the PSR chro

106 Packaging in aluminum laminated polyethylene under ambie

107 NCP) is the basic structural unit for genome packaging in eukaryotic cells and consists of DNA wound

108 he release of LTB4 from cells occurs through packaging in exosomes.

109 protamines mediate the near crystalline DNA packaging in most vertebrate sperm cells.

110 ctions of disulfide linkages for in vivo DNA packaging in sperm chromatin.

111 e and highlighted the critical role of waste packaging in successful sterilization.

112 ains both enzymatic activities necessary for packaging in such viruses: the adenosine triphosphatase

113 radable packaging material to reduce plastic packaging in the food industry.

114 RNA secondary structures involved in genome packaging in the picornavirus foot-and-mouth disease vir

115 with those of HPIV1 F in an effort to direct packaging in the vector particles.

116 sine ((Cap)1G) are specifically selected for packaging in virions, consistent with a recent report.

117 ructural compaction which may facilitate DNA packaging in vivo.

118 of the mechanisms surrounding exosomal cargo packaging, including viral proteins.

119 DS-Cav1 stabilized pre-F, with or without packaging, induced higher titers of pre-F specific antib

120 Recently the attention in the packaging industry regarding the use of bioplastics has

121 onspecific DNA and duplexes that contain the packaging initiation sequence, cos.

122 to wrap viral genome around the ring during packaging initiation.

123 basic understanding of paramyxovirus genome packaging interactions and also have implications for th

124 d matrix, potentially explaining how Rubisco packaging into a pyrenoid could have evolved across a br

125 necessary and sufficient to allow RNA genome packaging into an HIV-1 particle has not been defined.

126 cargos by adaptor proteins, leading to cargo packaging into coated vesicles destined for the endolyso

127 To study the mechanisms of RNA packaging into exosomes, we devised a purification schem

128 ng is required for cytoplasmic localization, packaging into HIV-1 particles, and antiviral activity.

129 ed at multiple sites to facilitate viral RNA packaging into immature nucleocapsids (NCs) and the earl

130 ours an amino acid code that dictates genome packaging into infectious virions.

131 s and transported to the plasma membrane for packaging into progeny virions.

132 ugh the cytoplasm, progressive assembly, and packaging into progeny virus particles.

133 the HPIV1 F protein in an effort to enhance packaging into the vector particle and immunogenicity.

134 f codon usage, together with efficient pre-F packaging into vector virions, significantly increased F

135 uently, the TP domain is necessary for pgRNA packaging into viral nucleocapsids and the initiation of

136 HIV-1 RNA genomes dimerize before packaging into virions, and RNA interacts with the viral

137 Genome packaging is an essential step to generate infectious HI

138 ation of RNAi scaffold design with Qbeta VLP packaging is demonstrated to be target-specific and effi

139 ull-length viral RNA, indicating that genome packaging is efficient and tightly regulated.

140 Genome packaging is strongly conserved in the complex double-st

141 directed from the MSC to viral particles for packaging is unknown.

142 From a practical point of view, PLA packaging is very well suited for semi-dry foods, but is

143 opose the signal for termination of 'Headful Packaging' is a DNA-dependent symmetrization of portal p

144 The coding sequence of CDH3 fits within the packaging limit of recombinant adeno-associated virus ve

145 The packaging machine consists of three components: portal,

146 effects of freezing and modified atmosphere packaging (MAP) (100% N2 and 50% N2+50% CO2) on some qua

147 ying the effect of three modified atmosphere packaging (MAP) conditions, all with high CO2 and residu

148 U.S.) ports of entry as larvae in solid wood packaging material (SWPM).

149 film can serve as a bioactive biodegradable packaging material to reduce plastic packaging in the fo

150 An antioxidant food packaging material was developed and applied to fresh mi

151 ere wrapped in special three-layer sheets of packaging material, some with a coating of REO (active p

152 class of next-generation food preservatives/packaging material.

153 ife of industrial bread and allowing to save packaging material.

154 tential application as an antibacterial food packaging material.

155 HY/gamma-CD-IC-NF) were fabricated as a food packaging material.

156 ious types of food are now commercialized in packaging materials based on poly(lactic acid) (PLA) due

157 te and immediate determination of the CTE of packaging materials is gaining importance because the de

158 h as the development of antimicrobial active packaging materials.

159 Improved understanding of RNA packaging may lead to novel vaccine approaches or target

160 standing of their capsid assembly and genome packaging mechanism is needed for improved vector produc

161 storage temperatures, storage duration, and packaging methods affected the contents of some bioactiv

162 ding global food trade data, processing, and packaging models.

163 olution resulted in markedly improved genome packaging (more than 133-fold), stability in blood (from

164 uential action of the ATPase ring in the DNA packaging motor of bacteriophage varphi29 is regulated b

165 WJ) of the pRNA from bacteriophage phi29 DNA packaging motor were examined previously for ocular deli

166 portal) that has negligible affinity for the packaging motor.

167 While the packaging motors have been described in some detail, the

168 employs one of the fastest and most powerful packaging motors, a pentamer of gp17 that translocates D

169 All viral dsDNA-packaging motors, including those of dsDNA/dsRNA bacteri

170 ein, we review the structures of viral dsDNA-packaging motors, the stoichiometries of motor component

171 genome into the tiny nuclear space, and this packaging must be compatible with proper gene expression

172 In the Phi29 bacteriophage, the DNA packaging nanomotor packs its double-stranded DNA genome

173 aging, AP), and some without REO (non active packaging, NAP), and stored at 4 degrees C for 20days.

174 o form 28-nm-diameter (T = 3) particles when packaging normal-composition RNAs.

175 Contrary to the prevailing model for vRNA packaging, NP does not bind vRNA uniformly in the A/WSN/

176 ha inhibits CAF-1- and ASF1A-H3-H4-dependent packaging of a DNA mismatch into a tetrasome.

177 c analysis of purified virions suggests that packaging of antirestriction components into P1 virions

178 We propose that IN-RNA interactions allow packaging of both the viral RNA genome and IN within the

179 propose that IN-RNA interactions ensure the packaging of both vRNPs and IN within the protective cap

180 spatially organized at multiple scales, from packaging of DNA around individual nucleosomes to segreg

181 Packaging of DNA into the nucleosome core particle (NCP)

182 rimary importance of membrane association in packaging of extracellular nanovesicle factors and indic

183 The packaging of genomic DNA into nucleosomes creates a barr

184 anti-viral targets.The mechanism underlying packaging of genomic RNA into viral particles is not wel

185 Selective packaging of HIV-1 genomic RNA (gRNA) requires the prese

186 eficient cell-free extracts, CAF-1-dependent packaging of irreparable O(6)-mG-T mispair-containing DN

187 the importance of CD63 presence for exosomal packaging of LMP1.

188 e 5' gag sequence are required for efficient packaging of non-viral RNA into HIV-1 particles, althoug

189 The packaging of proteins into discrete compartments is an e

190 TMCT modification greatly increased packaging of RSV F into the vector particles but also in

191 Chromatin remodelers catalyze dynamic packaging of the genome by carrying out nucleosome assem

192 Packaging of the genome into a protein capsid and its su

193 he mechanism by which Psi promotes selective packaging of the gRNA is not well understood.

194 The specific packaging of the hepatitis C virus (HCV) genome is hypot

195 identified RNA sequences involved in genome packaging of the picornavirus foot-and-mouth disease vir

196 randa et al. (2017) show that production and packaging of the single-copy genome into gametes during

197 This process involves packaging of the viral genome into chromatin, which is o

198 t role in viral transcription initiation and packaging of the viral genome into viral nucleocapsids.

199 porter RNAs is not sufficient to mediate the packaging of these RNA into HIV-1 particles.

200 gene to the 5' UTR strongly facilitates the packaging of two reporter RNAs; such RNAs can be package

201 functions including alternative splicing and packaging of unspliced genomic RNA into virions.

202 g optimized combination of pretreatment with packaging on shelf life of minimally processed cilantro

203 dication packaging (from original medication packaging-only care homes) and multi-compartment complia

204 ns, which is independent of either viral RNA packaging or DNA synthesis, multiple substitutions in th

205 , and the TMCT modification did not increase packaging or immunogenicity but rather reduced the stabi

206 counterfeiters often 'recycle' used genuine packaging, or employ good quality simulants.

207 f a function of this protein relevant to DNA packaging other than its interaction with other terminas

208 humidity within storage facilities, type of packaging (oxygen-permeable or not), and premix composit

209 We also mapped phage 9 g DNA packaging (pac) site containing two 21-bp direct repeats

210 TerS is essential for packaging, particularly for genome recognition, but its

211 l measurements of liposomal changes in lipid packaging, permeability, and fluidity are appropriate to

212 HBoV1 mRNAs transcribed from the pHBoV1NSCap packaging plasmid and its derivatives in HEK 293 cells.

213 s vector production system, we used an HBoV1 packaging plasmid, pHBoV1NSCap, that harbors HBoV1 nonst

214 We find that CCMV CP is also capable of packaging polyU RNAs, which-unlike normal-composition RN

215 50 atmospheres as a result of the phage DNA-packaging process.

216 teins play an important role in these unique packaging properties of the repressed chromatin.

217 high affinity binding to the large terminase packaging protein, and a symmetric ring in the mature vi

218 e the presence and modification of these DNA-packaging proteins provide a scaffold for docking of mul

219 -immunoprecipitates and colocalizes with AdV packaging proteins.

220 the mechanism used by HIV-1 to ensure genome packaging provides significant insights into viral assem

221 ors were embedded in a specifically designed packaging providing enough stiffness to penetrate into s

222 but its precise role in the DNA cleavage and packaging reaction is unclear.

223 kaging, we found that its ability to mediate packaging relies heavily on the context of the downstrea

224 ped RNA viruses, the requirements for genome packaging remain poorly understood.

225 arding the mechanism of tRNA(Lys3) and LysRS packaging remain unknown.

226 PE is largely utilized in packaging, representing approximately 40% of total deman

227 ily transferable methodology for identifying packaging requirements in many other viruses.IMPORTANCE

228 ready present in the genome fulfilling their packaging role.

229 on the application of barrier materials for packaging, sealing, or encapsulation of the active subst

230 The intrinsic amphipathic lipid packaging sensor (ALPS) motif within HOPS Vps41, a targe

231 can occur during manufacturing, processing, packaging, shipment and storage.

232 he high affinity interaction of a single RNA packaging signal (PS) with capsid protein(s) (most +ssRN

233 o cis-acting RNA regulatory elements: the 5' packaging signal (Psi) bound by Gag during genome encaps

234 sought to determine the extent to which IAV packaging signal divergence impacts reassortment between

235 Our study aimed to quantify the impact of packaging signal mismatch on IAV reassortment using the

236 1N1 lineages is unlikely to be restricted by packaging signal mismatch, while movement of the HA segm

237 coded identical proteins but differed in the packaging signal regions on a single segment.

238 ence of a cis-acting RNA element called the 'packaging signal' (Psi).

239 termine if evolutionary conserved cis-acting packaging signal(s) were preserved after recoding.

240 IV3 in three forms: (i) pre-F without vector-packaging signal, (ii) pre-F with vector-packaging signa

241 tor-packaging signal, (ii) pre-F with vector-packaging signal, and (iii) secreted pre-F ectodomain tr

242 oteins and genomic RNA that would occur in a packaging signal-mediated assembly process.

243 ides 1-127 is predicted to contain five such packaging signals (PSs).

244 These packaging signals are segment and strain specific, and a

245 Our results indicate that the importance of packaging signals in IAV reassortment is segment depende

246 el, simple, and transferable to the study of packaging signals in other RNA viruses.

247 "cryptic, sequence-degenerate, dispersed RNA packaging signals mapping along the entire viral genome"

248 Thus, the packaging signals of the HA segment could be an importan

249 We found that the packaging signals on the HA segment, but not the NA or N

250 The data are consistent with RNA packaging signals playing essential roles in virion asse

251 How the packaging signals regulate the specific incorporation of

252 reference for the segment containing matched packaging signals relative to the background of the viru

253 Influenza A virus (IAV) RNA packaging signals serve to direct the incorporation of I

254 ents carrying homologous versus heterologous packaging signals were incorporated into reassortant pro

255 ctural elements from within the RNA, termed "packaging signals" (PS), contact coat proteins and facil

256 nt 6 (NA) or segment 8 (NS) carried modified packaging signals, there was no significant preference f

257 was no significant preference for homologous packaging signals.

258 and N-P) and investigated the use of vector packaging signals.

259 codon usage, reduced CpG content, and vector packaging significantly improved vector immunogenicity a

260 effectiveness of polylactic acid (PLA) based packaging solution to store red fresh meat during its re

261 ctures that might play a role in determining packaging specificity do not survive codon pair recoding

262 y for +ssRNA viruses: step I, acquisition of packaging specificity, either (a) by specific recognitio

263 genome" play the critical role in poliovirus packaging specificity.

264 ack chemicals during production, processing, packaging, storage, and transport.

265 Processing, packaging, storage, and transportation also impart diffe

266 The combination of the formulation and packaging strategies gave the best result (83% shelf lif

267 Nonetheless, TMCT-directed packaging substantially increased the titers of high-qua

268 The packaging substrate is typically a concatemer composed o

269 dy provides a foundation to develop a better packaging system for rAAV2/HBoV1 vector production.

270 This study compared the effect of different packaging systems on industrial durum wheat bread shelf-

271 With the growth of 3D packaging technology and the development of flexible, tr

272 read shelf-life, with regard to thermoformed packaging (TF) and flow-packaging (FP).

273 error rate was seen for original medication packaging than multi-compartment compliance aids (9.3% a

274 These new methods for packaging the AAV2 genome may be useful for generating r

275 CENP-A is required for packaging the centromere and for the proper separation o

276 upled nucleosome assembly is a major step in packaging the newly synthesized DNA into chromatin, but

277 uence is evolved de novo that is optimal for packaging the RNA into capsids, while also containing ca

278 At the late stage of DNA packaging, the negatively charged genome is increasingly

279 eloped viruses must protect their genomes by packaging them into an outer shell or capsid of virus-en

280 onenveloped viruses protect their genomes by packaging them into an outer shell or capsid of virus-en

281 ns between a smoked meat product and plastic packaging to find a possibility of elimination of polycy

282 ctically every stage, ranging from chromatin packaging to mRNA translation.

283 Genome packaging triggers rearrangement of the coat protein and

284 The packaging under modified atmosphere MAP was carried out

285 rough the addition of a rosemary extract and packaging under nitrogen.

286 L release from the capsid upon completion of packaging unlocks the nuclease domains to cleave DNA.

287 f ATP hydrolysis, 2.5- to 4.5-fold lower DNA packaging velocity, and required an activator protein, g

288 In addition to packaging viral pregenomic RNA (pgRNA) and DNA polymeras

289 have revealed important insights into genome packaging, virion assembly, cell entry, and other stages

290 Furthermore, LMP1 packaging was severely impaired in CD63 knockout cells,

291 Enhanced packaging was substantially attenuating in hamsters (10-

292 requirements for exosome biogenesis and RNA packaging, we devised a cell-free reaction that recapitu

293 e HIV-1 RNA is known to be important for RNA packaging, we found that its ability to mediate packagin

294 examine the role of the gag sequence in RNA packaging, we replaced the 5' gag sequence in the HIV-1

295 -1 to achieve such high efficiency of genome packaging when a packageable viral RNA is not required f

296 ng an ultrathin, flexible, and imperceptible packaging with conformal epidermal contact.

297 e intended contact of materials used in food packaging with simulants.

298 ves all types of foods, feed, beverages, and packaging, with the potential for serious health, as wel

299 GTP binding of K-Ras was dispensable for its packaging within extracellular nanovesicles and for the

300 farnesylation of K-Ras was required for its packaging within extracellular nanovesicles, yet express