ライフサイエンスコーパス: palmitate

1 ha expression in IRPTCs by high glucose plus palmitate.

2 monoesterification and diesterification with palmitate.

3 ived macrophages to the saturated fatty acid palmitate.

4 l laurate (ML), methyl myristate, and methyl palmitate.

5 cultures elongated laurate to myristate and palmitate.

6 starch-palmitate, sucrose-oleate and sucrose-palmitate.

7 starch-palmitate < sucrose-oleate < sucrose-palmitate.

8 ed an autophagic response to oleate, but not palmitate.

9 n the liver is more hepatotoxic than dietary palmitate.

10 abundant evidence that its lipid A contains palmitate.

11 ored on p-NP-butyrate, p-NP-laurate and p-NP-palmitate.

12 than those of cells not exposed to elevated palmitate.

13 equired for the modification of lipid A with palmitate.

14 rotene, lycopene, phylloquinone, and retinyl palmitate.

15 omoting sugars and unusually large stores of palmitate.

16 is responsible for the de novo synthesis of palmitate.

17 FA levels (R(2) = 0.99, P < 0.0001), whereas palmitate (16:0) was negatively correlated (R(2) = 0.83,

18 Finally, LPS (0.5-2 ng.ml(-1) ) and palmitate (20 and 30 mum) acted synergistically to induc

19 ridol decanoate 25 to 200 mg or paliperidone palmitate 39 to 234 mg every month for as long as 24 mon

20 se (HG, 27.5 mmol/L) medium and treated with palmitate (50 mumol/L) or bovine serum albumin (BSA) for

21 oneogenesis from fructose), blood VLDL-(13)C palmitate (a marker of hepatic de novo lipogenesis), and

22 Palmitate (a) induced the accumulation of sphingomyelin

23 Short-term treatments of myotubes with palmitate, a ceramide precursor, or directly with cerami

24 microscopy, we discovered that metabolism of palmitate, a prevalent saturated fatty acid (SFA), could

25 Importantly, mice fed MCD starch-palmitate accumulated as much hepatic palmitate as mice

26 Palmitate activated the Toll-like receptor 4 (TLR4)/nucl

27 d in macrophages by the saturated fatty acid palmitate, acts via its receptor Unc5b to block their mi

28 Our results suggest that palmitate acutely activates mRNA translation and that th

29 We found that palmitate acutely increases polyribosome occupancy of to

30 The addition of two palmitate acyl chains is unique to B. parapertussis.

31 atalytic effect on lipid oxidation: ascorbyl palmitate addition and co-spray-drying of heme iron with

32 s quantification of retinyl acetate, retinyl palmitate, alpha-tocopherol and gamma-tocopherol, revers

33 re isolated and extracted, and alpha-retinyl palmitate (alphaRP) and retinyl palmitate were measured

34 (14)C-palmitate and (14)C-oleate oxidation rates and incorpora

35 ry islets with glucolipotoxicity (0.5 mmol/L palmitate and 25 mmol/L glucose) increases LC3 II, a mar

36 esence of its naturally occurring acyl donor palmitate and a nonhydrolyzable palmitoyl-CoA analog.

37 uced by lysosomal stress inducers, including palmitate and chloroquine, or Torin1, an inhibitor of ma

38 we found an increase in the uptake of (14)C-palmitate and fatty acid transporter CD36 that was furth

39 e treated with physiologic concentrations of palmitate and glucose and assessed for alterations in mi

40 e found differential bioenergetic effects of palmitate and glucose on resting and energetically chall

41 hydrogen peroxide) or metabolic stress (high palmitate and high glucose) inactivated SirT1 by reversi

42 on in primary hepatocytes using radiolabeled palmitate and in mice using indirect calorimetry.

43 o increase the water solubility of Vitamin A Palmitate and its stability against different external f

44 c neurodegeneration requires the presence of palmitate and may be a result of enhanced NO production.

45 l, diacylglycerol, and monoacylglycerol with palmitate and myristate acyl chains.

46 aturated and unsaturated fatty acids such as palmitate and oleate, respectively, triggered autophagy,

47 rived "danger signals" such as ceramides and palmitate and promote the adipose tissue inflammation in

48 Using a dual pulse-chase strategy comparing palmitate and protein half-lives, we found knockdown or

49 entified two approved drugs, ascorbic acid 6-palmitate and salmon sperm protamine, that effectively i

50 Palmitate and stearate induced cholangiocyte lipoapoptos

51 ed that it was modified with the fatty acids palmitate and stearate.

52 3)C label incorporation into the fatty acids palmitate and stearate.

53 could be rapidly restored by the addition of palmitate and substantially reduced production of oxidiz

54 e incubated mouse beta-cells and islets with palmitate and then studied mRNA translation by polyribos

55 ingested a high-fat meal containing retinyl palmitate and were given either GLP-2 or placebo 7 hours

56 lpxL2 mutant lacked the 2-hydroxymyristate, palmitate, and 4-aminoarabinose decorations found in the

57 0% of newly stored hepatic triglyceride (TG)-palmitate, and after 5 days (study B), approximately 60%

58 Kupffer cells were stimulated with oleate or palmitate, and levels of M1/M2 polarization markers and

59 version into blood (13)C glucose, VLDL-(13)C palmitate, and postprandial plasma lactate concentration

60 measurement of TRL triglyceride, TRL retinyl palmitate, and TRL apoB-48 levels.

61 alis L.) (ROSM) (200-1500mg/kg) and ascorbyl palmitate (AP) (100-300mg/kg) were tested for 18hopen pa

62 Ascorbyl palmitate (AP) and ascorbyl stearate (AS) are examples o

63 Electrooxidation of ascorbyl palmitate (AP) over gold screen-printed electrode (AuSPE

64 All of these effects of palmitate are fatty acid specific because oleate (C18:1,

65 bjects fasting levels of the free fatty acid palmitate are raised.

66 de production in HEK293 cells incubated with palmitate as a direct substrate for SPT reaction.

67 on of ETFbeta in mouse C2C12 cells oxidizing palmitate as an energy source reduced the consumption of

68 starch-palmitate accumulated as much hepatic palmitate as mice fed MCD sucrose-oleate, yet their degr

69 ng alpha-tocopherol, beta-carotene, ascorbyl palmitate, ascorbic acid, citric acid, and their combina

70 The most effective antioxidant was ascorbyl palmitate at 0.005%, and a synergistic antioxidant effec

71 to the triacylglycerol class and containing palmitate at the first position) were significantly gene

72 methyl laurate, methyl myristate, and methyl palmitate, attracting healthy flies, which in turn becom

73 Dietary palmitate becomes toxic when combined with dietary sugar

74 ardiac triglyceride accumulation and ex vivo palmitate beta-oxidation.

75 These lipids likely bind in the palmitate binding cavity as observed in tablysin-15, sin

76 of binding affinity as tablysin-15, a known palmitate-binding protein.

77 diated dimerization of the TLR4-MD2 complex, palmitate binds a monomeric TLR4-MD2 complex that trigge

78 nsulin resistance induced by high glucose or palmitate but not H2O2.

79 Conversely, autophagy triggered by palmitate, but not oleate, required AMPK, PKR and JNK1 a

80 Media from L6 myotubes treated with palmitate-but not palmitoleate-induced THP1 monocyte mig

81 ic nalmefene derivatives were evaluated: the palmitate (C16), the octadecyl glutarate diester (C18-C5

82 nversion in anaerobic bioreactors results in palmitate (C16:0) accumulation.

83 Palmitate (C16:0) induces apoptosis of insulin-secreting

84 We report that palmitate (C16:0, 200 muM) significantly modulates the m

85 The fatty acid palmitate can activate death receptor 5 (DR5) on hepatoc

86 Palmitate caused apoptosis of enteric neuronal cells ass

87 from RAW 264.7 or Kupffer cells loaded with palmitate (CM-P), phosphorylation of stress kinases and

88 for the Pro90Ser CD36 mutation, whereas when palmitate concentration was slightly increased, uptake i

89 Plasma palmitate concentrations and flux were suppressed to 23

90 Therefore, pathologic palmitate concentrations promote the acquisition of a sp

91 of v-ATPase in cardiomyocytes exposed to low palmitate concentrations reduced insulin sensitivity and

92 ditions of suppressed and slightly increased palmitate concentrations.

93 e the expression of CCL19 and TRIB3 Besides, palmitate conditions macrophages for exacerbated proinfl

94 During suppressed palmitate conditions, muscle and adipose palmitate uptak

95 rtially share genetic basis of T2D; and c) 1-palmitate containing TAGs may provide additional insight

96 ECs glucose stimulates PFKFB3 expression and palmitate contributes to increased proinflammatory respo

97 As a percentage of triacylglycerol palmitate, de novo lipogenesis was 2-fold higher in subj

98 Interestingly, palmitate decreased PFKFB3 expression and increased proi

99 ction of oleate, but not of the saturated FA palmitate, decreased food intake and increased locomotor

100 mice and chronic exposure of human islets to palmitate decreases endogenous sorcin expression while l

101 onstrate that Sonic Hedgehog signals via the palmitate-dependent arm of a two-pronged contact with Pa

102 The palmitate-dependent interaction is also abolished in con

103 The palmitate-dependent interaction with Patched1 is specifi

104 ate Patched1 inhibition is caused by direct, palmitate-dependent interaction with the Sonic Hedgehog

105 Investigation of palmitate-dependent respiration in mutant fibroblasts sh

106 By contrast, mice fed MCD sucrose-palmitate developed severe liver injury, worse than that

107 with the SCD1 substrate (and FASN product), palmitate, did not rescue cells.

108 cific deletion of Sptlc2 is not required for palmitate-driven Nlrp3 inflammasome activation.

109 to knock out the Sms2 gene recapitulated the palmitate effects by inducing the accumulation of SM pre

110 intermediates accounting for the deleterious palmitate effects.

111 In general, ascorbyl palmitate, either alone or in combination with the co-sp

112 In conclusion, oleate and palmitate elicit an opposite cross-talk between macropha

113 in macrophages/Kupffer cells stimulated with palmitate, enhanced arginase 1 and lower leukotriene B4

114 We have demonstrated that palmitate enhances glucose-stimulated insulin secretion

115 ssion apparently affects the partitioning of palmitate-enriched diacylglycerol between the phosphatid

116 s hypothesis, C57BL/6 mice were either fed a palmitate-enriched high fat diet or administered with ch

117 e might be explained by the observation that palmitate esterification influenced the cis-trans equili

118 this study was to determine whether dietary palmitate exerts the same toxicity as carbohydrate-deriv

119 Unlike LPS, palmitate exposure does not activate STAT1, and its tran

120 omethoxyphenylhydrazone (FCCP), we show that palmitate exposure induced comparable peak OCR and highe

121 Palmitate exposure to neonatal rat ventricular cardiomyo

122 here were no significant changes in the IC50(palmitate)f (19 +/- 2 compared with 24 +/- 3 muIU/mL), a

123 eded to suppress palmitate flux by 50% (IC50(palmitate)f).In the omega-3 group, the EPA and DHA contr

124 Under these conditions, palmitate failed to alter levels of SMs, which are the m

125 the insulin concentration needed to suppress palmitate flux by 50% (IC50(palmitate)f).In the omega-3

126 conditioned medium from myotubes exposed to palmitate for 4 h significantly reduced apoptosis of mur

127 Treatment of myotubes with 0.5 mmol/L palmitate for 4 h, but not with oleate, promoted an incr

128 itrophenyl butyrate) or solid (p-nitrophenyl palmitate) form can be mixed or solubilized, respectivel

129 copherols in salad vegetables and 2) retinyl palmitate formed from the provitamin A carotenoids.Women

130 The enzyme then transfers palmitate from itself onto substrate proteins.

131 zyme PagP is responsible for the transfer of palmitate from outer membrane phospholipids to lipid A.

132 he response to membrane aberrancy induced by palmitate from unfolded protein stress, our analysis sho

133 ith an oral dose of either VA (6 mug retinyl palmitate/g body weight) or canola oil (control), both c

134 y failure was 49 (33.8%) in the paliperidone palmitate group and 47 (32.4%) in the haloperidol decano

135 However, long-term exposure to palmitate (>8 hours) enhances ROS generation, which is a

136 Ascorbyl palmitate had less inhibitory effect than erythorbic aci

137 According to the literature, retinyl palmitate has been found to be the most abundant vitamin

138 Mice fed a low-palmitate HFD did not develop a similar phenotype.

139 s PNPLA3 as a lipase responsible for retinyl-palmitate hydrolysis in HSCs in humans.

140 which the enzyme first modifies itself with palmitate in a process termed autoacylation.

141 B), approximately 60% of newly deposited TG-palmitate in adipose tissues originated from this pathwa

142 The stability of Vitamin A Palmitate in the complexes towards temperature, oxygen a

143 del of steatohepatitis, carbohydrate-derived palmitate in the liver is more hepatotoxic than dietary

144 lso correlated positively with the amount of palmitate in the liver, but the relationship was weak.

145 ts the same toxicity as carbohydrate-derived palmitate in the MCD model of fatty liver disease.

146 ative stress in cultured myotubes exposed to palmitate in the presence of a beta-oxidation inhibitor.

147 HUVECs were treated with and without palmitate in the presence or absence of EMPs.

148 tes, namely glutamine, pyruvate, glucose, or palmitate, in mitochondria.

149 Treatment with 1 mm palmitate increases de novo ceramide synthesis in both c

150 Treatment with the fatty acid palmitate induced oxidative stress and cell death in AML

151 L from healthy humans and lean mice inhibits palmitate-induced adipocyte inflammation; however, the e

152 ignaling and that induction of MAM prevented palmitate-induced alterations of insulin signaling in Hu

153 vealed significantly reduced NEFA uptake and palmitate-induced apoptosis in microperfused Slc27a2(-/-

154 riptome study identified novel mechanisms of palmitate-induced beta-cell dysfunction and death.

155 Although palmitate-induced endoplasmic reticulum stress and nucle

156 BBR treatment also caused a decrease in palmitate-induced fat deposition in primary mouse hepato

157 yme expression and glucose output and blunts palmitate-induced hepatocyte fat deposition in an Akt-de

158 ditioned medium led to a 20-fold increase in palmitate-induced IL-8 expression by hepatocytes.

159 sed JNK and NF-kappaB activation and blocked palmitate-induced IL-8 expression in hepatocytes.

160 ced JNK and NF-kappaB activity and increased palmitate-induced IL-8 secretion.

161 3, thereby releasing the brake and enhancing palmitate-induced IL-8 synthesis and secretion.

162 the ability of SAA-containing HDL to inhibit palmitate-induced inflammation and cholesterol efflux.

163 om mice injected with AgNO3 fails to inhibit palmitate-induced inflammation and reduces cholesterol e

164 Mildronate reversed palmitate-induced insulin resistance concomitant with an

165 In contrast, palmitate-induced lipid droplet formation is significant

166 in a PGC1alpha-dependent manner and reduced palmitate-induced lipotoxicity.

167 th normoxia, hypoxia significantly increased palmitate-induced mRNA expression and protein secretion

168 Additional studies showed increased palmitate-induced oxidative stress, mitochondrial and ly

169 function in a model of free fatty acid (FFA) palmitate-induced oxidative stress.

170 Adiponectin also attenuated palmitate-induced reactive oxygen species production in

171 Palmitate-induced ROS generation in human CD68(low)CD14(

172 Here, we demonstrate that palmitate-induced sorcin downregulation and subsequent i

173 ospholipids was studied in HepG2 cells under palmitate-induced steatosis.

174 m torpid squirrel brain show a high level of palmitate-induced uncoupling.

175 The mechanism of palmitate-induced v-ATPase inhibition involved its disso

176 downregulation of BECN1 and PIK3C3 abolished palmitate-induced, but not oleate-induced, autophagy in

177 Together, these results suggest that palmitate induces DRG neuron mitochondrial depolarizatio

178 ring 1 h of exercise at 50% VO2max ([U-(13)C]palmitate infusion combined with electron microscopy of

179 a 2-step pancreatic clamping with a [U-(13)C]palmitate infusion to determine the insulin concentratio

180 mitate storage was assessed using a [U-(13)C]palmitate infusion to measure palmitate kinetics and an

181 Palmitate inhibited IGFBP-3 secretion by THP-1 macrophag

182 Palmitate inhibited transcription factors controlling be

183 Under lipotoxic conditions, palmitate inhibits hepatic macrophage secretion of IGFBP

184 over under different conditions (glucose +/- palmitate +/- insulin +/- dichloroacetate).

185 purified wild-type PNPLA3 hydrolyzes retinyl palmitate into retinol and palmitic acid.

186 espectively, clearly shows that the perfused palmitate is chain-elongated.

187 In the case of palmitate, its accelerated uptake ultimately precipitate

188 patocytes and Huh7 cells were incubated with palmitate, its metabolite lysophosphatidylcholine, or di

189 ing a [U-(13)C]palmitate infusion to measure palmitate kinetics and an intravenous palmitate radiotra

190 cells, lipid stress by exposure to elevated palmitate leaves unchanged the rate by which MC4R and tr

191 ed from the LENK ester prodrug - tyrosinyl(1)palmitate-leucine(5)-enkephalin (TPLENK) were coated wit

192 wer FASN activity in PINK1 mutants decreases palmitate levels and increases the levels of cardiolipin

193 The ability of chronically elevated palmitate levels to simultaneously increase basal secret

194 n the WD-fed BMPR2-mutant RV showed impaired palmitate-linked oxygen consumption, and metabolomics an

195 patitis, in the order starch-oleate < starch-palmitate < sucrose-oleate < sucrose-palmitate.

196 erexpressing SNRK have decreased glucose and palmitate metabolism and oxygen consumption, but maintai

197 Palmitate modified expression of 17 splicing factors and

198 sis of transcription factor binding sites in palmitate-modified transcripts revealed a role for PAX4,

199 The hydrophobic palmitate moiety is covalently attached to a cysteine re

200 fference between these two, the less complex palmitate monoester was chosen to demonstrate that dog p

201 Agonist-induced turnover of palmitate occurs predominantly on Cys-265.

202 te, and monitoring (13) C incorporation into palmitate of circulating very low-density lipoprotein tr

203 d, catechin, alpha tocopherol, ascorbic acid palmitate) on the physical and chemical stability of lut

204 the enzyme responsible for the attachment of palmitate onto Shh, is a novel target for inhibition of

205 ia containing carbohydrate with either (13)C-palmitate or (13)C-oleate for dynamic (13)C nuclear magn

206 12 or human muscle cells were incubated with palmitate or directly with ceramide for short or long pe

207 loss and increased ER stress in response to palmitate or lipopolysaccharide (LPS).

208 ytes (PMHs) and Huh7 cells were treated with palmitate or lysophosphatidylcholine (LPC).

209 n of primary hepatocytes and Huh7 cells with palmitate or lysophosphatidylcholine increased their rel

210 40 agonist TAK-875 being more effective than palmitate or oleate in recruiting beta-arrestins 1 and 2

211 this study, we have evaluated the impact of palmitate or oleate overload of macrophage/Kupffer cells

212 ern diet (WD) (35% kcal from fat enriched in palmitate) or a purified regular diet (16.9% kcal from f

213 thweight neonates to NVAS (50 000 IU retinyl palmitate) or placebo together with their Bacillus Calme

214 tyl-CoA (e.g. [(13)C6]glucose or [1,2-(13)C2]palmitate) or/and M1 acetyl-CoA (e.g. [1-(13)C]octanoate

215 otubes to either high glucose concentration, palmitate, or H2O2 decreases insulin-induced Akt phospho

216 and in rodent and human cardiomyocytes upon palmitate overexposure, and appeared as an early lipid-i

217 gnificantly reduced mitochondrial incomplete palmitate oxidation and increased indices of pyruvate de

218 human myotubes, ACSL6 overexpression reduced palmitate oxidation and PGC-1alpha mRNA.

219 kout mouse hearts have increased glucose and palmitate oxidation and UCP3.

220 These reductions were not retained for palmitate oxidation in primary myotubes (P = 0.38); howe

221 rfusions demonstrated a profound increase in palmitate oxidation relative to wild-type hearts (3.6 ti

222 Furthermore, palmitate oxidation was elevated in the white adipose ti

223 ered by small interfering RNA against DAPK3, palmitate oxidation was increased.

224 ncreased glucose oxidation at the expense of palmitate oxidation, preventing the increase in anaplero

225 content, mitochondrial respiratory rates and palmitate oxidation.

226 2.16s(-1), respectively, when p-nitrophenyl palmitate (p-NPP) was used as the substrate.

227 BMDM from low fat-fed mice exposed to palmitate (PA) for 18 h ex vivo also showed elevated exp

228 Palmitate (PA)-induced changes in intracellular hydrogen

229 ability is confirmed by lipase p-nitrophenyl palmitate (PNP) assay.

230 These actions were recapitulated in vitro in palmitate-primed hepatocytes and adipocytes incubated wi

231 Suppression of IGF binding protein-3 by palmitate promotes hepatic inflammatory responses.

232 The addition of ascorbyl palmitate provided protection against oxidation and loss

233 Maternal insulin value at 50% palmitate Ra suppression (IC50) for palmitate suppressio

234 easure palmitate kinetics and an intravenous palmitate radiotracer bolus/timed biopsy.

235 erases APT1 and APT2 - are known to catalyze palmitate removal from cytosolic cysteine residues.

236 a-acylated structures containing one and two palmitates, respectively.

237 A palmitate-rich diet, which increases serum 27OHC, or APP

238 -secreting alpha-cells, we hypothesized that palmitate simultaneously stimulates secretion of glucago

239 Oleate, but not palmitate, stimulated an autophagic response that requir

240 Here, we show that palmitate-stimulated CD11b(+)F4/80(low) hepatic infiltra

241 phate (S1P) levels are not only increased in palmitate-stimulated pancreatic beta-cells but also regu

242 nsulin, niacin, and saline groups, abdominal palmitate storage rates were 0.25 +/- 0.05 vs. 0.25 +/-

243 Direct palmitate storage was assessed using a [U-(13)C]palmitat

244 rate-fat combinations: starch-oleate, starch-palmitate, sucrose-oleate and sucrose-palmitate.

245 However, lipid deprivation or palmitate supplementation has no effect on NF-kappaB exp

246 1 expression, which is able to be rescued by palmitate supplementation.

247 e at 50% palmitate Ra suppression (IC50) for palmitate suppression with insulinemia was higher in OB+

248 ion of fatty acid synthase (FASN), the major palmitate-synthesizing enzyme.

249 TG turnover in TAC was greatly reduced with palmitate (TAC, 46.7+/-12.2 nmol/g dry weight per min; S

250 With palmitate, TAC hearts contained 48% less TG versus SHAM

251 Supplementation of palmitate, the end product of FASN catalysis, rescued ca

252 the reversible posttranslational addition of palmitate to cysteines and promotes membrane binding and

253 ultured C2C12 myotubes, using BSA-conjugated palmitate to increase synthesis of endogenous sphingolip

254 cystic fibrosis patients constitutively add palmitate to lipid A, the membrane anchor of lipopolysac

255 his hypothesis in rats by infusing [U-(13)C] palmitate to measure rates of fatty acid esterification

256 Purified PagP transferred palmitate to PG consistent with PagP acylation of both l

257 ases catalyze the addition of the fatty acid palmitate to proteins on the cytoplasmic leaflet of cell

258 rotein S-palmitoylation which adds 16-carbon palmitate to specific cysteines and contributes to vario

259 PA PagP transfers palmitate to the 3' position of lipid A, in contrast to

260 alent attachment of the 16-carbon fatty acid palmitate to the N-terminal cysteine of Sonic Hedgehog (

261 [(14)C]Choline and [(3)H]palmitate tracking shows that SMS1 overexpression appare

262 In palmitate-treated C2C12 skeletal myotubes, GLP-1(32-36)a

263 itogen-activated protein kinase signaling in palmitate-treated cells.

264 Palmitate-treated DRG neurons also exhibited a reduction

265 related with mitochondrial depolarization in palmitate-treated DRG neurons.

266 vels of p62 were elevated in comparison with palmitate-treated hLrp1(+/+) hepatocytes, suggesting tha

267 Palmitate-treated hLrp1(-/-) hepatocytes displayed simil

268 uencing to map transcripts expressed in five palmitate-treated human islet preparations, observing 1,

269 modestly reduced IL-1beta gene expression in palmitate-treated hypoxic macrophages.

270 The secretome of hypoxic palmitate-treated macrophages promoted IL-6 and macropha

271 beta and reduced the hypoxic potentiation in palmitate-treated macrophages.

272 elevated ROS generation are also observed in palmitate-treated neonatal rat ventricular cardiomyocyte

273 Exposure of palmitate-treated THP-1 macrophages to IGFBP-3-deficient

274 ion from human islets, to be enhanced during palmitate treatment at normoglycemia.

275 s of endoplasmic reticulum (ER) stress after palmitate treatment compared with similarly treated hLrp

276 Palmitate treatment significantly reduced the number of

277 itoylation of Huntingtin, but did not affect palmitate turnover on postsynaptic density protein 95 (P

278 characterized ABHD17 proteins can accelerate palmitate turnover on PSD95 and N-Ras.

279 Indeed, palmitate turnover regulates Ras trafficking and signali

280 Palmitate turnover therefore is required for localizing

281 eceptor signaling in neuronal cells requires palmitate turnover.

282 sed palmitate conditions, muscle and adipose palmitate uptake were markedly reduced in homozygotes bu

283 DHHC proteins transfer palmitate via a two-step catalytic mechanism in which th

284 chizoaffective disorder, use of paliperidone palmitate vs haloperidol decanoate did not result in a s

285 ed a high-fat diet or hepatocytes exposed to palmitate was accompanied by reduced PPARbeta/delta and

286 The spontaneous curvature of palmitate was calculated by molecular dynamic simulation

287 Tissue retinyl palmitate was inversely and significantly correlated wit

288 lutamine, whereas the capacity for oxidizing palmitate was limited to human hepatocarcinoma Huh7 cell

289 Exogenous palmitate was partitioned to different pools from endoge

290 sults showed a notably increase of Vitamin A Palmitate water solubility and stability in front of tho

291 oxia-potentiated inflammation induced by SFA palmitate, we found that the AMP-mimetic AMPK activator

292 lpha-retinyl palmitate (alphaRP) and retinyl palmitate were measured over 12 h postprandially via hig

293 sters, beta-carotene, and beta-cryptoxanthin palmitate were the most abundant in peels and pulp of al

294 es suggest that BTA121 binds lipids, notably palmitate with a similar order of binding affinity as ta

295 ter-soluble inclusion complexes of Vitamin A Palmitate with beta-cyclodextrins, without the use of or

296 observed in tablysin-15, since MpPR-1i binds palmitate with comparable affinity as tablysin-15.

297 was a weak downward trend of tissue retinyl palmitate with increasing fibrosis stage.

298 acylcarnitines (C4:0, C14:0, C16:0) or with palmitate with or without carnitine acyltransferase inhi

299 in T2D (P = 0.03 for oleate and P = 0.11 for palmitate), with a strong correlation of TAG incorporati

300 ason why oleate is continuously converted to palmitate without further degradation via beta-oxidation