ライフサイエンスコーパス: palmitic acid

1 mice and stimulated with TLR2 ligand and/or palmitic acid.

2 (MUFA), Polyunsatured Fatty Acids (PUFA) and Palmitic Acid.

3 r a breakfast meal that contained deuterated palmitic acid.

4 , or C20-sphing-4-enin derivative coupled to palmitic acid.

5 of toxicity palmitoleic acid > oleic acid > palmitic acid.

6 kdown McA cells incubated in MCD medium with palmitic acid.

7 by the enzymatic product of FA2H, 2-hydroxy palmitic acid.

8 rtially reversed by treatment with 2-hydroxy palmitic acid.

9 cells on conjugated linoleic acid but not on palmitic acid.

10 d with a monolayer of free base porphyrin or palmitic acid.

11 with dipalmitoylphosphatidylcholine and with palmitic acid.

12 ae) showed that NgDelta0-ELO1 could elongate palmitic acid.

13 by labeling of the protein with [3H]-labeled palmitic acid.

14 oA serve as substrates for FAS to synthesize palmitic acid.

15 recombinant OMP G1a contain covalently bound palmitic acid.

16 re each modified by the covalent addition of palmitic acid.

17 xtures of dipalmitoylphosphatidylcholine and palmitic acid.

18 eric multifunctional enzyme that synthesizes palmitic acid.

19 cilitated by linoleic acid and diminished by palmitic acid.

20 oUD344A expressed in yeast failed to release palmitic acid.

21 etween bilayers because of ionization of the palmitic acid.

22 binding to TL was reduced in the presence of palmitic acid.

23 Instead, dSREBP processing is blocked by palmitic acid.

24 glycoprotein is modified by the addition of palmitic acid.

25 tion of miR-30b and 378 but not by oleate or palmitic acid.

26 regulation) but could be induced in vitro by palmitic acid.

27 obtained through the extent of diffusion of palmitic acid.

28 s may be mediated by lower triglycerides and palmitic acid.

29 er triglyceride levels and lower circulating palmitic acid.

30 rived from beta-oxidation of [1,2,3,4-(13)C4]palmitic acid.

31 ydrolyzes retinyl palmitate into retinol and palmitic acid.

32 evidence for beta-oxidation of perfused M+4 palmitic acid.

33 se macrophages treated with high glucose and palmitic acid.

34 hospholipid fraction were oleic equally with palmitic acids.

35 ined three types of fatty acids, 0.48 microg palmitic acid, 0.61 microg stearic acid and 0.83 microg

36 ence: myristic acid 1.15 [95% CI 1.09-1.22], palmitic acid 1.26 [1.15-1.37], and stearic acid 1.06 [1

37 Changes from baseline with an LFD for palmitic acid (16:0) (3-11% increase), behenic (22:0) an

38 ha-synuclein gene-ablated mice with [1-(14)C]palmitic acid (16:0) and assessed fatty acid uptake and

39 ated associations of major circulating SFAs [palmitic acid (16:0) and stearic acid (18:0)] and MUFA [

40 epidemiologic studies, circulating levels of palmitic acid (16:0) are associated with diabetes; howev

41 .10433-10434AA >GC was associated with lower palmitic acid (16:0) concentration but higher oleic (18:

42 d the hypothesis that high-fat meals rich in palmitic acid (16:0) in the sn-2 position decrease lipem

43 ic acid, oleic acid, and palmitoleic acid to palmitic acid (16:0) ratio were significantly increased

44 elations of 4 fatty acids in the DNL pathway-palmitic acid (16:0), palmitoleic acid (16:1n-7), 7-hexa

45 Palmitic acid (16:0), stearic acid (18:0), palmitoleic a

46 the principal fatty acid produced by FAS is palmitic acid (16:0).

47 6:1omega-3)] and the ratio of palmitoleic to palmitic acid (16:1n-7/16:0), as an estimation of the ac

48 orated more of the radioiodinated version of palmitic acid, 16-[(125)I]iodohexadecanoic acid.

49 5, the ligand affinity for 16-(9-anthroyloxy)palmitic acid (16AP) and 8-anilino-1-naphthalenesulfonic

50 ains biologically important fatty acids like palmitic acid (2.06%), linolenic acid (2.56%), and oleic

51 cid) PC > di18:2n-6(linoleic acid) PC > 16:0(palmitic acid),22:6n-3(DHA) PC > di18:3n-3(alpha-linolen

52 he principal fatty acids in the species were palmitic acid (23.38-30.49%) and linoleic acid (20.19-29

53 C analysis for MAE cottonseed oil determined palmitic acid (23.6%), stearic acid (2.3%), oleic acid (

54 rimarily of oleic acid (33.35%), followed by palmitic acid (26.16%), stearic acid (10.07%), palmitela

55 the fluorescent fatty acid 2-(9-anthroyloxy)palmitic acid (2AP) similarly, but there were clear diff

56 of cellular phospholipids labeled with [(3)H]palmitic acid, [(3)H]oleic acid, or [(3)H]choline chlori

57 Major fatty acids were palmitic acid (44%) and oleic acid (46%) in ghee, while

58 6%), while the main saturated fatty acid was palmitic acid (5-29%).

59 Supplementing the HCT-8 cells with palmitic acid (80 mum), the end product of fatty acid sy

60 id (66.73%) followed by oleic acid (14.78%), palmitic acid (9.74%), and stearic acid (7.37%).

61 er position on the hydroxy fatty acid (e.g., palmitic-acid-9-hydroxy-stearic-acid, 9-PAHSA).

62 tous bound ligands, which were identified as palmitic acid (a fatty acid) and isopropyl laurate (a fa

63 results reveal mechanistic insight about how palmitic acid activates TLR2, upregulates NALP3 expressi

64 In vitro, palmitic acid alone did not increase TLR2 signaling-targ

65 Chop(+/+) and Chop(-/-) were challenged with palmitic acid, an abundant saturated free fatty acid in

66 Palmitic acid, an efficacious stimulator of human PGHS-2

67 we report the metabolic incorporation of the palmitic acid analog 17-octadecynoic acid (17-ODYA) in c

68 e residues or pretreatment of cells with the palmitic acid analog 2-bromopalmitate, reduced the [3H]p

69 ition allowed the conjugation of fatty acid (palmitic acid analog) to Uox with the HSA binding capaci

70 eld likely due to the enhanced solubility of palmitic acid analog.

71 African palm oil) with only 10-15% of total palmitic acid and 6-20% of stearic acid acylated in the

72 then given a mixed meal containing [ 1-(13)C]palmitic acid and [1-(13)C]oleic acid.

73 was found in the largest amount, followed by palmitic acid and behenic acid.

74 y are modified by the addition of N-terminal palmitic acid and C-terminal cholesterol moieties, both

75 mide (PEA), the naturally occurring amide of palmitic acid and ethanolamine, reduces pain and inflamm

76 o the Western diet fat composition) to a low-palmitic acid and high-oleic acid diet (HOA; similar to

77 recipitating PLM from ARVM loaded with [(3)H]palmitic acid and immunoblotting following streptavidin

78 It is responsible for the elongation of palmitic acid and is involved in PUFA biosynthesis.

79 In summary, both palmitic acid and linoleic acid exert inhibitory effect

80 s (FAs), including oleic acid, stearic acid, palmitic acid and myristic acid, were the primary chemic

81 ss than 8 nM and turnover numbers similar to palmitic acid and N-palmitoylglycine.

82 dothelial cells (HCAECs) incubated with both palmitic acid and oleic acid.

83 ride as the major component and were rich in palmitic acid and oleic acid.

84 f the primary product was observed with both palmitic acid and palmitoleic acid as substrates.

85 hanistic level, PLA2denat -MB containing 20% palmitic acid and PEG induced PLA2-specific IgA and incr

86 Further, competition between palmitic acid and retinol reveals only palmitate bound t

87 We found a positive association between palmitic acid and risk of total, localized, and low-grad

88 (11R)-HLA we have prepared the corresponding palmitic acid and stearic acid esters, mayolene-16 (1) a

89 n this large prospective cohort, circulating palmitic acid and stearic acid were associated with high

90 At baseline, circulating palmitic acid and stearic acid were positively associate

91 y myristic acid; instead, it was acylated by palmitic acid and stearic acid.

92 fatty acids, and caveolin-1 was acylated by palmitic acid and stearic acid.

93 ants were used to determine the influence of palmitic acid and synthetic peptides based on the surfac

94 sphocholine resulted in the rapid release of palmitic acid and the selective accumulation of 2-arachi

95 Compared with fresh fish samples, palmitic acid and tocopherol content decreased in a 20%

96 od for the analysis of lauric, myristic, and palmitic acids and their omega and omega(-1) hydroxylate

97 Here, we confirm that saturated (e.g. palmitic acid) and unsaturated (e.g. docosahexaenoic aci

98 dia supplemented with 28 mM glucose, 200 muM palmitic acid, and 200 muM oleic acid as a cellular mode

99 ncreased incorporation of leucine, uptake of palmitic acid, and abundance of fatty acid transport pro

100 ly by Oil Red O staining in cells exposed to palmitic acid, and it was accompanied by an increase in

101 low concentrations of gamma-linolenic acid, palmitic acid, and long-chain monounsaturated fatty acid

102 e damage than other free fatty acids such as palmitic acid, and mediates selective loss of intrahepat

103 toleic acid, myristoleic acid, stearic acid, palmitic acid, and myristic acid had little effect.

104 acids, gamma-linolenic acid, linoleic acid, palmitic acid, and oleic acid.

105 Metabolic studies with radiolabeled serine, palmitic acid, and phosphorylcholine revealed that the u

106 114 solubilization, radiolabeling with [(3)H]palmitic acid, and sucrose density gradient membrane par

107 t were measured (14:0 [myristic acid], 16:0 [palmitic acid], and 18:0 [stearic acid]) were positively

108 inhibited Akt-mediated eNOS phosphorylation, palmitic acid appeared to affect the upstream signaling.

109 Here we show that both TLR2 and palmitic acid are required for activation of the inflamm

110 -fat diets, specifically those enriched with palmitic acid, are CNS mediated via PKC-theta activation

111 y lutein esters esterified with myristic and palmitic acid as monoesters or diesters, were found.

112 Using sphingosine and palmitic acid as substrates, the enzyme exhibited Michae

113 hases within both leaflets was obtained with palmitic acid as the anchoring group.

114 majority of alpha-retinol was esterified to palmitic acid (as compared with other fatty acids).alpha

115 This finding was specific for palmitic acid, as the monounsaturated fatty acid, oleic

116 ference for choline phospholipids containing palmitic acid at the sn-1 position that could be exploit

117 Adjustment for triglycerides and palmitic acid attenuated the associations toward the nul

118 content of linoleic acid and high content of palmitic acid behaved exceptionally well.

119 Non-substrate FAs like palmitic acid bind Eallo of PGHSs stimulating human (hu)

120 The [(3)H]palmitic acid binds to the coated phospholipid through h

121 ids present in Liposyn II, linoleic acid and palmitic acid, both reduced proliferation.

122 nd reacts with a higher turnover number than palmitic acid but with unaltered regiospecificity along

123 Further, MCD medium with palmitic acid, but not oleic or linoleic acids, maximall

124 process initiated at the elongation step of palmitic acid by Delta0-ELO1, thus acting as a committin

125 omega(-1) oxidation of lauric, myristic, and palmitic acids by CYP4A enzymes were measured and compar

126 s a mixture of saturated and monounsaturated palmitic acid (C(16)).

127 rns of (R)-tuberculostearic acid (C19:0) and palmitic acid (C16:0) and their mass spectral characteri

128 ified enzymes was carried out for long chain palmitic acid (C16:0) and very long chain lignoceric aci

129 f the enzyme was carried out for long chain (palmitic acid, C16:0) and very long chain (lignoceric ac

130 with 4-HPR for 2 h, in the presence of [(3)H]palmitic acid, caused sequential formation of [(3)H]sphi

131 These results demonstrate that a palmitic acid-ceramide pathway accounts for impaired int

132 the (2)H NMR order parameter profile of the palmitic acid chain in POPC.

133 in yeast resulted in an accumulation of free palmitic acid, changes in the phospholipid profiles and

134 suspensions containing 2:1:1 skin ceramides:palmitic acid:cholesterol, similar to the lipid composit

135 Palmitic acid, chosen as the case study of single fatty

136 of L. interrogans in medium containing [14C]palmitic acid, confirming that it is a lipoprotein.

137 As a proof-of-concept, we show that single palmitic acid conjugated to superfolder green fluorescen

138 TLR2 and palmitic acid cooperatively activate the inflammasome in

139 Incubation in palmitic acid decreased apoE secretion from these cells.

140 iquitinated tyrosinase whereas, in contrast, palmitic acid decreased it.

141 itination of many cellular proteins, whereas palmitic acid decreased such ubiquitination, as compared

142 TO901317 also shifted palmitic acid-derived FFAs into biologically inactive tr

143 In the presence of TLR2 ligand, palmitic acid did induce caspase-1 activation and releas

144 , crossover trials that compared a 3-wk high-palmitic acid diet (HPA; similar to the Western diet fat

145 sent multiple lines of evidence showing that palmitic acid directly activates TLR2, a major TLR expre

146 Here, we synthesized the R- and S- palmitic acid ester of 9-hydroxystearic acid (R-9-PAHSA,

147 Specifically, CHO-containing OxPCs with palmitic acid esterified to the sn-1 position of the gly

148 y novel class of endogenous lipids, branched palmitic acid esters of hydroxy stearic acids (PAHSAs),

149 6 different FAHFA families, such as branched palmitic acid esters of hydroxy stearic acids (PAHSAs);

150 Palmitic acid esters of hydroxy-stearic acids (PAHSAs) a

151 This solvent has an efficiency of palmitic acid extraction of 34.14%, and the amount of an

152 h adjustment for demographics and lifestyle, palmitic acid (extreme-quintile HR: 1.89; 95% CI: 1.27,

153 , the enzyme that catalyzes the formation of palmitic acid from malonyl-CoA, drove NF2-deficient cell

154 unt of 2-DCB formed from the model compounds palmitic acid, glyceryl tripalmitate and 1,3-dipalmitoyl

155 ffect decreased in the sequence oleic acid > palmitic acid > myristic acid > linoleic acid > linoleni

156 nd that coating the particles with insoluble palmitic acid had little effect on the deliquescence, ef

157 ative domain but only a very small amount of palmitic acid hydroxylase activity.

158 ified by a fatty acid anchor on Cys-9 with a palmitic acid in about 60% and, surprisingly, an oleic a

159 al cognitive decline increased with elevated palmitic acid in both fractions and with high arachidoni

160 significantly reduced ROS levels induced by palmitic acid in human aortic endothelial cells.

161 mpletely inhibited the induction of MCP-1 by palmitic acid in mesangial cells.

162 are similar, except for a small increase in palmitic acid in plastoglobuli, suggesting a common orig

163 nous upregulation of C(16:0)-Cer mediated by palmitic acid in RAW 264.7 macrophages led to a signific

164 pattern and preferred arachidonic acid over palmitic acid in substrates, also indicating the presenc

165 acids with glycine and the high abundance of palmitic acid in the brain, we hypothesized the endogeno

166 ort chain acyl-CoAs, palmitoylcarnitine, and palmitic acid in the presence of CoASH were without effe

167 Fats with a higher proportion of palmitic acid in the sn-2 position decrease postprandial

168 LSFAs), with 20 or more carbons, differ from palmitic acid in their biological activities, and little

169 cid analog 2-bromopalmitate, reduced the [3H]palmitic acid incorporation into CD44 and prevented CD44

170 Palmitic acid incorporation kinetics indicated that, at

171 ation of exogenously administered [9,10-(3)H]palmitic acid increased 4-fold during differentiation.

172 Culture of AML12 hepatocytes with palmitic acid increased cytotoxicity through apoptosis a

173 ncreased in aggressive HCCs; monounsaturated palmitic acid increased migration and invasion of cultur

174 vity led to decreased PTEN expression, while palmitic acid increased PTEN in myotubes in a p38-depend

175 on of autophagy by chloroquine (CQ) enhanced palmitic acid-induced apoptosis accompanied by increased

176 ed generation of ROS was associated with the palmitic acid-induced autophagy in podocytes.

177 expression in cultured podocytes and reduced palmitic acid-induced cell death.

178 imilarly, overexpression of Scd-1 attenuated palmitic acid-induced cell death.

179 ll interfering RNA knockdown of RIP3 reduced palmitic acid-induced cytotoxicity.

180 This study characterizes palmitic acid-induced lipotoxicity (PA-LTx) in Schwann c

181 yoblasts, silencing of cathepsin K inhibited palmitic acid-induced release of cytochrome c from mitoc

182 agy by rapamycin (Rap) remarkably suppressed palmitic acid-induced ROS generation and apoptosis.

183 Moreover, lipopolysaccharide or palmitic acid-induced TLR4 activation and high glucose f

184 Palmitic acid inhibits insulin signaling by promoting PT

185 abolic incorporation of an alkynyl analog of palmitic acid into cellular proteins coupled with click

186 -translational protein modification in which palmitic acid is added to cysteine residues, allowing as

187 In these experiments, the palmitic acid is delivered as a complex with delipidated

188 lation and is well tolerated, whereas excess palmitic acid is poorly incorporated into triglyceride a

189 In this study, we demonstrate using [(3)H]palmitic acid labeling and acyl-biotinyl exchange that n

190 of palmitoylation with tunicamycin and [(3)H]palmitic acid labeling demonstrated an estrogen-induced,

191 [(3)H]palmitic acid labeling demonstrated that both native and

192 The synthesis of glucose esters with palmitic acid, lauric acid and hexanoic acid using lipas

193 Activation of TLR2 by palmitic acid leads to expression of pro-IL-1beta that i

194 at hearts were perfused with [1,2,3,4-(13)C4]palmitic acid (M+4), and the isotopic patterns of myocar

195 Palmitic acid makes the monolayer rigid at low surface t

196 This study also suggests that SFA palmitic acid may play an important role in MetS-associa

197 chromosome 10) activity and transcription by palmitic acid mediated the inhibitory effects on insulin

198 trometry identified 2 saturated fatty acids, palmitic acid methyl ester (PAME) and stearic acid methy

199 hiphilic drug formulation additives based on palmitic acid-modified poly(ethylene glycol) (Pal-PEG) a

200 d from HSV-1 gD, were covalently linked to a palmitic acid moiety (lipopeptides) and delivered subcut

201 an untilted condensed phase of the the pure palmitic acid monolayer.

202 lator of human PGHS-2, binds only E(allo) in palmitic acid/murine PGHS-2 co-crystals.

203 t, respectively), and for few individual FA (palmitic acid, oleic acid), having R(CV)(2) higher than

204 fore characterized S-acylation event linking palmitic acid, oleic acid, and stearic acid at C78 of th

205 ficient values indicated higher measures for palmitic acid, oleic acid, unsaturated and monounsaturat

206 Total hepatic FA profiling revealed a higher palmitic acid/oleic acid (PA/OA) ratio in WT mice, compa

207 The reversible thioester linkage of palmitic acid on cysteines, known as protein S-palmitoyl

208 analogue partially reproduces the effects of palmitic acid on insulin signaling.

209 s effects of diets high in fat, specifically palmitic acid, on hypothalamic insulin activity in rats

210 We show that palmitic acid or palm oil increases ceramide production

211 Fluorescent analogs of either palmitic acid or phosphatidylcholine were applied to the

212 acid, whereas it is decreased in response to palmitic acid or triglycerides.

213 Incubation of lauric acid, palmitic acid, or oleic acid (OA) with human sebocytes d

214 immune cells stimulated with the fatty acid, palmitic acid, or with lipopolysaccharide.

215 HB) plasma levels as well as BHB release and palmitic acid oxidation by isolated hepatocytes.

216 d by octanoate injection; BHB production and palmitic acid oxidation were normal in liver homogenates

217 e activity of ACC and suppressed the rate of palmitic acid oxidation.

218 data show that the saturated fatty acid (FA) palmitic acid (PA) activates the inflammasome and induce

219 on a model system composed of a monolayer of palmitic acid (PA) and a surfactant protein B peptide, S

220 n this study we sought to examine effects of palmitic acid (PA) and oleic acid, two of the common die

221 r these studies, both saturated fatty acids (palmitic acid (PA) and stearic acid (SA)) and unsaturate

222 The levels of saturated palmitic acid (PA) from most of the tested seed oils wer

223 Accumulation of palmitic acid (PA) in cells from nonadipose tissues is k

224 carboxylic acid of atmospherically relevant palmitic acid (PA) is accompanied by binding of the Mg(2

225 of the lung-surfactant peptide SP-B1-25 in a palmitic acid (PA) monolayer.

226 t-specific protein SP-B, on the structure of palmitic acid (PA) monolayers.

227 In the present study, we demonstrated that palmitic acid (PA) promoted autophagy in podocytes.

228 as suggested that diets with a high ratio of palmitic acid (PA) to oleic acid (OA) increase risk of c

229 h PKR after induction of metabolic stress by palmitic acid (PA) treatment.

230 omplex of bovine beta-lactoglobulin (Lg) and palmitic acid (PA), (Lg + PA)(n-) --> Lg(n-) + PA, at th

231 AP-1 pathways in response to treatment with palmitic acid (PA), a FFA.

232 ma nonesterified fatty acids discovered that palmitic acid (PA), a natural peroxisome proliferator-ac

233 Relative to diets enriched in palmitic acid (PA), diets rich in oleic acid (OA) are as

234 ated effects of a saturated free fatty acid, palmitic acid (PA), on endothelial cell responses to VEG

235 (DHA), relative to the saturated fatty acid palmitic acid (PA), on the hepatic expression of apo A-I

236 phagosomes), with abundant engulfed cargo in palmitic acid (PA)- or glucose-treated cells, indicating

237 andomly divided in groups and subjected to a palmitic acid (PA)- or oleic acid (OA)-enriched high-fat

238 We have shown that palmitic acid (PA)-induced lipotoxicity (PA-LTx) in nerv

239 c acid (OA) is oxidized more rapidly than is palmitic acid (PA).

240 were provided by the investigators, and the palmitic acid (PA):oleic acid (OA) ratio was manipulated

241 c)-keyhole limpet hemocyanin (KLH) and Tn(c)-palmitic acid (PAM) with the saponin immunologic adjuvan

242 leation on internally mixed ammonium sulfate/palmitic acid particles, namely optical microscopy coupl

243 rthermore, characteristic fatty acids (e.g., palmitic acid), quinolone signal, and riboflavin fragmen

244 Serum stearic acid/palmitic acid ratio as a potential predictor of diabetes

245 Treatment of KO hepatocytes with palmitic acid reduced cell viability and increased apopt

246 Binding of palmitic acid renders these regulators incapable of inte

247 t of the mutant lipid A may contain an added palmitic acid residue.

248 Among them, palmitic acid resulted the most abundant, followed by om

249 that treatment with the saturated fatty acid palmitic acid results in sustained JNK activation and in

250 Numerous proteins undergo modification by palmitic acid (S-acylation) for their biological functio

251 RYGB, we found higher baseline stearic acid/palmitic acid (S/P) ratio.

252 id (OA/SA), and lower levels of stearic acid/palmitic acid (SA/PA) and arachidonic acid/dihomo-gamma-

253 ontaneous degradation of tyrosinase, whereas palmitic acid (saturated fatty acid, C16:0) retarded the

254 An endogenous ligand, possibly palmitic acid, serves to illuminate the mode and mechani

255 Palmitic acid showed the lower concentration in all expe

256 rocarbon chains, and with replacement of the palmitic acid sn-1 chains by oleic acid.

257 Moreover, in isolated macrophages, palmitic acid stimulated cyclooxygenase-2 induction and

258 , only myristic acid, and to a lesser extent palmitic acid, stimulated eNOS.

259 Similar to that in the kFABP-palmitic acid structure, the acid moiety in 1 is proxima

260 1-stearoylglycerol, 1-palmitoylglycerol, and palmitic acid, suggesting that the high serum alpha-feto

261 alkanes and aromatic acid derivatives, being palmitic acid, tetracosanol and octacosanol the most abu

262 The equation x = 0.02t(0.5) was obtained for palmitic acid that could be used to find its position in

263 is used in the ACC/FAS coupled system, [(3)H]palmitic acid, the final product, is readily detected by

264 were treated with the saturated fatty acid, palmitic acid, the insulin-signaling pathway was impaire

265 However, evidence that palmitic acid, the major dietary saturated fatty acid, c

266 Levels of monounsaturated palmitic acid, the product of SCD activity, were increas

267 flammation, our in vitro studies showed that palmitic acid-the most abundant saturated fatty acid (SF

268 d by introducing MC fatty acids with reduced palmitic acid through lipase acidolysis.

269 e-like molecule from purified BioI indicates palmitic acid to be bound.

270 re given an intravenous infusion of [(2)H(2)]palmitic acid to investigate systemic nonesterified fatt

271 re also fed a mixed meal containing [U-(13)C]palmitic acid to investigate the contribution of dietary

272 hophysiologically relevant concentrations of palmitic acid to simulate the excessive influx of fatty

273 Thus, the covalent attachment of palmitic acid to the Cys residues of CPD has a functiona

274 ceramide synthesis improves the response of palmitic acid-treated Caco-2/TC7 enterocytes to insulin.

275 Where palmitic acid treatment activated Chop(+/+) and Chop(-/-

276 In the latter, palmitic acid treatment inhibits glucose-induced insulin

277 ressed by high-fat diet feeding and in vitro palmitic acid treatment.

278 to the PTEN promoter, which was increased by palmitic acid treatment.

279 duction, whereas the formulation bearing 80% palmitic acid triggered the production of IFN-gamma, IgG

280 that the fabH mutant retained low levels of palmitic acid upon fatty acid starvation.

281 CNS exposure to palmitic acid via direct infusion or by oral gavage incr

282 uintile compared with the lowest quintile of palmitic acid was 1.47 (95% CI: 0.97, 2.23; P for trend

283 Importantly, palmitic acid was found to induce significantly elevated

284 The highest palmitic acid was observed in the oil obtained from untr

285 Palmitic acid was predominant in 79% of biscuits and rep

286 Palmitic acid was prevalent among the saturated fatty ac

287 the same TAG molecule together with C18 FAs, palmitic acid was typically in the sn-2 position.

288 Interestingly, when [(3)H]palmitic acid was used as the substrate for incorporatio

289 iosynthetic labeling experiments using [(3)H]palmitic acid, we found that the CD8-myr(-)eNOS chimera

290 The saturated FFA stearic acid and palmitic acid were less efficacious than unsaturated FFA

291 efects in macrophage phagocytosis induced by palmitic acid were mimicked by PGE2 and PGD2 and were re

292 s turnover rates of docosahexaenoic acid and palmitic acid were unaffected.

293 Higher amount of oleic, linoleic and palmitic acids were observed in olive oils.

294 ereas the saturated fatty acids, stearic and palmitic acids, were totally ineffective.

295 NL of 254, 2 u less than the nominal mass of palmitic acid, whereas the analogous terminal COOH-conta

296 ulting in release of arachidonic, oleic, and palmitic acids, whereas overexpression of cPLA(2)alpha r

297 nd introduced close to the carboxyl group of palmitic acid, which is specifically esterified to the s

298 xis was found to be particularly enriched in palmitic acid, while the seed coat/aleurone layer accumu

299 metabolic and molecular effects of replacing palmitic acid with oleic acid; evidence for a dose-respo

300 ydomonas cells with per-deuterated D31-16:0 (palmitic) acid yielded D31-18:0 (stearic) acid, D29-18:1