ライフサイエンスコーパス: palmitoleate

1 ention studies that target circulating trans-palmitoleate.

2 rinsically greater production and release of palmitoleate.

3 ning systemic concentrations of the lipokine palmitoleate.

4 alterations characterized by an increase in palmitoleate.

5 d in beta-cells exposed to palmitate but not palmitoleate.

6 esence of a buried 16-carbon fatty acid, cis-palmitoleate.

7 nduced M1-like polarization by administering palmitoleate.

8 a large hydrophobic pocket that accommodates palmitoleate.

9 e oleate (18:1Delta9) were nontoxic, whereas palmitoleate (16:1Delta9) was a potent growth inhibitor.

10 release of the insulin-sensitizing lipokine palmitoleate (16:1n-7).

11 ied 167 yeast mutants as sensitive to 0.5 mm palmitoleate, 45% of which define pathways that were con

12 ction of active Wnt depends on attachment of palmitoleate, a monounsaturated fatty acid, to a conserv

13 synthesis of the monounsaturated fatty acids palmitoleate and oleate.

14 ependent determinants of plasma phospholipid palmitoleate and relations of palmitoleate with metaboli

15 c hypertrophy involving the lipokine C16:1n7 palmitoleate as a molecular co-mediator.

16 filing also led to identification of C16:1n7-palmitoleate as an adipose tissue-derived lipid hormone

17 The appearance of palmitoleate at 12 degrees C is accompanied by a decline

18 50BM3 (residues 73-84) which participates in palmitoleate binding was subjected to scanning chimerage

19 esize the monounsaturated fatty acids (MUFA) palmitoleate (C(16:1)) and oleate (C(18:1)), both of whi

20 The equivalent value for palmitoleate (C16:1 cis) was 3.1.

21 Post-translational attachment of palmitoleate (C16:1) to a conserved Ser in Wnt proteins

22 rated fatty acids, mainly oleate (C18:1) and palmitoleate (C16:1), which are components of membrane p

23 uced uniformly labeled palmitate (C16:0) and palmitoleate (C16:1).

24 statistically significant declines in muscle palmitoleate CoA (16:1), oleate CoA (18:1), or total LCA

25 trans-Palmitoleate concentrations correlated positively with s

26 After multivariable adjustment, trans-palmitoleate concentrations were associated with higher

27 tors and other potential confounders, higher palmitoleate concentrations were independently associate

28 anges-are associated with higher circulating palmitoleate concentrations.

29 h independent lifestyle correlates of higher palmitoleate concentrations.

30 d palmitoylated proteins to their respective palmitoleated derivatives.

31 Interestingly, cells treated with palmitoleate exerted a sustainable level of cIAP1, where

32 ndently related to plasma phospholipid trans-palmitoleate; how trans-palmitoleate related to major me

33 the independent determinants of circulating palmitoleate in free-living humans and whether palmitole

34 lipid profiles also displayed an increase in palmitoleate in HFD-Tg mice compared with controls.

35 The replacement of laurate with palmitoleate in lipid A may reflect the desirability of

36 type E. coli grown at 12 degrees C contained palmitoleate in place of laurate, whereas the lipid A of

37 While both palmitate and palmitoleate induced an overt ER stress response, lipoto

38 m L6 myotubes treated with palmitate-but not palmitoleate-induced THP1 monocyte migration across tran

39 Strains lacking lpxP fail to incorporate palmitoleate into their lipid A at 12 degrees C but make

40 Circulating trans-palmitoleate is associated with higher LDL cholesterol b

41 Circulating trans-palmitoleate is associated with lower insulin resistance

42 Palmitoleate is not present in lipid A isolated from Esc

43 lmitoleate in free-living humans and whether palmitoleate is related to lower metabolic risk and the

44 Circulating palmitoleate is robustly associated with multiple metabo

45 In consonance, the serum C16:1n7 palmitoleate level exhibited a significantly positive co

46 Higher trans-palmitoleate levels were associated with slightly lower

47 s most strongly associated with higher trans-palmitoleate levels.

48 a carboxylesterase that removes an essential palmitoleate moiety from Wnt proteins and thus constitut

49 tricts Wg signaling by cleaving an essential palmitoleate moiety.

50 Transfer of palmitate, palmitoleate, or R-3-hydroxymyristate was very slow.

51 Notably, 6-h incubation with palmitoleate (PO) reversed the proinflammatory gene expr

52 a phospholipid trans-palmitoleate; how trans-palmitoleate related to major metabolic risk factors; an

53 major metabolic risk factors; and how trans-palmitoleate related to new-onset diabetes (304 incident

54 ) is a membrane-bound O-acyltransferase that palmitoleates the Wnts and hence is essential for their

55 Palmitoleate, the other main unsaturated fatty acid of S

56 dipose tissue uses lipokines such as C16:1n7-palmitoleate to communicate with distant organs and regu

57 Emerging evidence suggests that trans-palmitoleate (trans 16:1n-7), a fatty acid in dairy and

58 (15:0), heptadecanoic acid (17:0), and trans palmitoleate (trans 16:1n-7), were associated with lower

59 Trans-palmitoleate (trans-16:1n-7) represents a distinctly exo

60 d cells to death in response to the nontoxic palmitoleate treatment.

61 The mean (+/- SD) palmitoleate value was 0.49 +/- 0.20% (range: 0.11-2.55%

62 Trans-palmitoleate was also associated with a substantially lo

63 However, palmitoleate was also associated with higher triglycerid

64 In prospective analyses, trans-palmitoleate was independently associated with lower inc

65 Palmitoleate was not significantly associated with incid

66 required for the biosynthesis of oleate and palmitoleate, which are the major monounsaturated fatty

67 We investigated the association of trans-palmitoleate with metabolic risk and incident diabetes i

68 a phospholipid palmitoleate and relations of palmitoleate with metabolic risk factors were investigat