ライフサイエンスコーパス: palmoplantar

1 psoriasis," "pustular," "skin," "rash," and "palmoplantar." All relevant articles in English were rev

2 he protein expression levels of DKK1 between palmoplantar and non-palmoplantar areas and the effects

3 Human and mouse WNT10A mutant palmoplantar and tongue epithelia also display specific

4 pression differences between volar (ventral; palmoplantar) and nonvolar (dorsal) human skin.

5 ffering types of psoriasis (plaque, guttate, palmoplantar, and late-onset), which excluded the possib

6 xplain why melanocytes stop migrating in the palmoplantar area during human embryogenesis.

7 levels of DKK1 between palmoplantar and non-palmoplantar areas and the effects of DKK1 on melanocyte

8 apping skin disorders: multiple self-healing palmoplantar carcinoma (MSPC) and familial keratosis lic

9 In addition to the palmoplantar distribution seen in other epidermolysis bu

10 idermolytic palmoplantar keratoderma (PPK or palmoplantar ectodermal dysplasia type III) is associate

11 We demonstrate here a role for AQP5 in the palmoplantar epidermis and propose that the altered AQP5

12 hanisms underlying hyperproliferation of the palmoplantar epidermis in both physiological and disease

13 protein which is predominantly expressed in palmoplantar epidermis is implicated in AD may shed new

14 ferentiation, and help explain why DKK1-rich palmoplantar epidermis is paler than non-palmoplantar ep

15 ich palmoplantar epidermis is paler than non-palmoplantar epidermis via mesenchymal-epithelial intera

16 clusively in the suprabasal keratinocytes of palmoplantar epidermis, have previously been demonstrate

17 focal epidermolysis in the spinous layer of palmoplantar epidermis, in comparison with cases of bull

18 riate keratoderma particularly affecting the palmoplantar epidermis, woolly hair and a dilated left v

19 is confined to the suprabasal layers of the palmoplantar epidermis.

20 lele is sufficient for the developing normal palmoplantar epidermis.

21 and maintaining the mechanical integrity of palmoplantar epidermis.

22 order characterized by recurrent episodes of palmoplantar erythema and epidermal peeling.

23 iting, diarrhea, skin rashes, mucositis, and palmoplantar erythrodysesthesias.

24 Palmoplantar fibroblasts significantly suppressed the gr

25 The melanocyte density in palmoplantar human skin (i.e., skin on the palms and the

26 ual facies, dental anomalies, hypotrichosis, palmoplantar hyperkeratosis and onychodysplasia, syndact

27 f life, affected individuals later developed palmoplantar hyperkeratosis with patchy erythema and sca

28 odermal dysplasia characterized by alopecia, palmoplantar hyperkeratosis, and nail dystrophy.

29 y the triad of nail dystrophy, alopecia, and palmoplantar hyperkeratosis.

30 alopecia, severe dystrophy of the nails, and palmoplantar hyperkeratosis.

31 m periods the skin may be normal, except for palmoplantar hyperkeratosis.

32 in a patient with autosomal dominant striate palmoplantar kerato-derma.

33 Epidermolytic palmoplantar keratoderma (EPPK) is an autosomal dominant

34 Epidermolytic palmoplantar keratoderma (EPPK) is one of >30 autosomal-

35 Epidermolytic palmoplantar keratoderma (EPPK, MIM #144200) is an autos

36 a congenita (PC) and focal non-epidermolytic palmoplantar keratoderma (FNEPPK).

37 ified KRT6C mutations in patients with focal palmoplantar keratoderma (FPPK), but debate concerning o

38 Focal non-epidermolytic palmoplantar keratoderma (PPK or palmoplantar ectodermal

39 mutations, Cx26-H73R and Cx26-S183F, causing palmoplantar keratoderma (PPK) and deafness.

40 Palmoplantar keratoderma (PPK) are debilitating lesions

41 Mutations in SLURP1 cause a palmoplantar keratoderma (PPK) known as mal de Meleda.

42 delG in the V2 domain of keratin 5), striate palmoplantar keratoderma (PPK), and ichthyosis hystrix C

43 ations in SLURP1 cause mal de Meleda, a rare palmoplantar keratoderma (PPK).

44 hic nail dystrophy, oral leukokeratosis, and palmoplantar keratoderma (PPK).

45 a dominantly inherited skin disease, striate palmoplantar keratoderma (SPPK), mapping to chromosome 1

46 MAPK/ERK signaling and is linked to striate palmoplantar keratoderma (SPPK).

47 The locus for a syndrome of focal palmoplantar keratoderma (Tylosis) associated with squam

48 autosomal recessive pattern, manifests with palmoplantar keratoderma and early, destructive periodon

49 olidify a link between Slurp2 deficiency and palmoplantar keratoderma and to be confident that the di

50 eratitis-ichthyosis-deafness (KID) syndrome, palmoplantar keratoderma associated with hearing loss, a

51 paper, we report three patients with severe palmoplantar keratoderma associated with ichthyosis and

52 Genetic heterogeneity of striate palmoplantar keratoderma has been demonstrated with path

53 d, scaly skin at birth, experience worsening palmoplantar keratoderma in childhood, and develop hundr

54 of keratin 1 (G4134A) that segregates with a palmoplantar keratoderma in three kindreds.

55 Palmoplantar keratoderma is a hallmark of pachyonychia c

56 The striate form of palmoplantar keratoderma is a rare autosomal dominant di

57 Autosomal-dominant diffuse nonepidermolytic palmoplantar keratoderma is characterized by the adoptio

58 smoplakin mutation in a proband with striate palmoplantar keratoderma that also results in a null all

59 ion, the patient's dermatologist treated his palmoplantar keratoderma with systemic retinoids.

60 Tylosis (focal non-epidermolytic palmoplantar keratoderma) is an autosomal dominant skin

61 osis on the volar surface of the paws (i.e., palmoplantar keratoderma), increased keratinocyte prolif

62 the K9 gene are known to cause epidermolytic palmoplantar keratoderma, a rare dominant-negative skin

63 ypes: nonsyndromic SNHL, syndromic SNHL with palmoplantar keratoderma, and KID.

64 Mal de Meleda is a rare form of palmoplantar keratoderma, and recently mutations in the

65 inant skin disease, diffuse nonepidermolytic palmoplantar keratoderma, and was investigated as a poss

66 s for the triad of autosomal recessive ARVC, palmoplantar keratoderma, and woolly hair (Naxos disease

67 gene that results in skin fragility, diffuse palmoplantar keratoderma, and woolly hair with no sympto

68 the triad of ARVC, diffuse nonepidermolytic palmoplantar keratoderma, and woolly hair.

69 s leading to keratinopathies such as striate palmoplantar keratoderma, as reported in this study.

70 of the autosomal dominant disorder, striate palmoplantar keratoderma, as well as an autosomal recess

71 ermatosis characterized by focal and diffuse palmoplantar keratoderma, hyperkeratotic plaques on the

72 prised nail dystrophy or nail loss, marginal palmoplantar keratoderma, hypodontia, enamel hypoplasia,

73 epidermolysis bullosa simplex, epidermolytic palmoplantar keratoderma, junctional epidermolysis bullo

74 characterized by sensorineural hearing loss, palmoplantar keratoderma, knuckle pads, and leukonychia,

75 Palmoplantar keratoderma, nail dystrophy, and enamel def

76 ensive mucocutaneous blisters, epidermolytic palmoplantar keratoderma, nail dystrophy, enamel dysplas

77 Focal nonepidermolytic palmoplantar keratoderma, natal teeth, and pili torti ma

78 autosomal-dominant syndrome characterized by palmoplantar keratoderma, oral precursor lesions, and a

79 calized or generalized scaling, and frequent palmoplantar keratoderma.

80 ic cardiomyopathy and the cutaneous disorder palmoplantar keratoderma.

81 for understanding the pathogenesis of human palmoplantar keratoderma.

82 predominantly by nail dystrophy and painful palmoplantar keratoderma.

83 eleda is a rare, autosomal recessive form of palmoplantar keratoderma.

84 ation family of British descent with striate palmoplantar keratoderma.

85 dominantly inherited skin disorder, striate palmoplantar keratoderma.

86 recapitulated the clinical features of human palmoplantar keratoderma: overcornification and thickeni

87 Palmoplantar keratodermas (PPKs) are a group of disorder

88 The palmoplantar keratodermas (PPKs) are a large group of cl

89 roup of disorders, known collectively as the palmoplantar keratodermas, are unified by the phenotypic

90 Nagashima-type palmoplantar keratosis (NPPK) is an autosomal recessive

91 The mice exhibited palmoplantar keratosis and progressive alopecia, leading

92 Some patients have only palmoplantar keratosis or periodontitis, and in rare ind

93 nce of cardiac dysfunction or fibroadiposis, palmoplantar keratosis, and alopecia, resembling the hum

94 Palmoplantar keratosis, varying from mild psoriasiform s

95 ersalis hereditaria in addition to punctuate palmoplantar keratosis.

96 mechanisms responsible for the formation of palmoplantar lesions in PC and FNEPPK patients.

97 e generated a mouse model to replicate these palmoplantar lesions.

98 er, this was not the case when patients with palmoplantar pustular psoriasis were not included in the

99 ns including generalized pustular psoriasis, palmoplantar pustular psoriasis, acrodermatitis continua

100 mutations were identified in both localized (palmoplantar pustular psoriasis, acrodermatitis continua

101 rders: generalized pustular psoriasis (GPP), palmoplantar pustulosis (PPP), and acute generalized exa

102 30.6%; eczema, 23.5%; xerosis cutis, 10.6%; palmoplantar pustulosis, 5.3%; psoriasis, 3.8%; other, 2

103 atopic dermatitis, Mal de Meleda, vitiligo, palmoplantar pustulosis, and pemphigus may be mediated,

104 skin from hair bearing, nonhair bearing, and palmoplantar regions.

105 ermis elicits the hypopigmented phenotype of palmoplantar skin due to suppression of melanocyte funct

106 icroarray analysis, fibroblasts derived from palmoplantar skin expressed high levels of dickkopf 1 (D

107 pression patterns of those proteins in human palmoplantar skin.

108 n patterns of those key proteins observed in palmoplantar skin.

109 h oesophageal cancer (TOC), characterized by palmoplantar thickening, upregulate K16 with robust down