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1 to characterize GATA6 function during human pancreas development.
2 sked if PAK4 might have a functional role in pancreas development.
3 nes involved in islet beta cell function and pancreas development.
4 of Hedgehog activity is critical for proper pancreas development.
5 lleviated the effect of knocking out UCP2 on pancreas development.
6 and maturation of islet progenitor cells in pancreas development.
7 aturation of islet progenitor cells in mouse pancreas development.
8 are common for initiating dorsal and ventral pancreas development.
9 ial role in eye, central nervous system, and pancreas development.
10 has to be regulated tightly to ensure proper pancreas development.
11 described during mammalian liver and ventral pancreas development.
12 signaling pathways that are also used during pancreas development.
13 a requirement for hedgehog signaling during pancreas development.
14 xpression patterns provide new insights into pancreas development.
15 he specificity of expression required during pancreas development.
16 upstream regulators of the BETA2 gene during pancreas development.
17 amily of signaling molecules that antagonize pancreas development.
18 identify genes expressed at early stages of pancreas development.
19 indicate that some of the genes could govern pancreas development.
20 been investigated in vivo in the context of pancreas development.
21 and provides a means for expanding embryonic pancreas development.
22 scription factor involved in eye, brain, and pancreas development.
23 ther NEUROG3 is required for human endocrine pancreas development.
24 suggests that PAK4 is dispensable for mouse pancreas development.
25 strate an essential role for p120 catenin in pancreas development.
26 man embryonic stem cells in a model of human pancreas development.
27 iation and morphogenetic events during human pancreas development.
28 SPR/Cas9 targeting PDX1, a critical gene for pancreas development.
29 cription factor for lens, lacrimal gland and pancreas development.
30 ity produces distinct cellular states during pancreas development.
31 sis is a human disorder caused by defects in pancreas development.
32 for ribosomal biogenesis genes in zebrafish pancreas development.
33 important role for Cdk4 in regulating early pancreas development.
34 d acinar cell neogenesis required for normal pancreas development.
35 ry transcription factor network during early pancreas development.
36 eration, cell survival, and cell size during pancreas development.
37 have investigated the role of Jarid2 during pancreas development.
38 inositol-3-OH kinase (PI3K) pathway controls pancreas development.
39 n the canonical Wnt pathway is essential for pancreas development.
40 f the mammalian pygopus ortholog, mPygo2, in pancreas development.
41 rther reveal specific functions for Hdac1 in pancreas development.
42 thways that regulate vhnf1 expression during pancreas development.
43 act genetically upstream of RA in directing pancreas development.
44 ignals have been implicated as regulators of pancreas development.
45 regut markers and is essential for liver and pancreas development.
46 tain foregut identity and to allow liver and pancreas development.
47 ate the gene expression cascades involved in pancreas development.
48 the miRNA processing enzyme Dicer1 early in pancreas development.
49 a transcription factor complex essential for pancreas development.
50 acinar and endocrine progenitor cells during pancreas development.
51 ial role in endoderm patterning and promotes pancreas development.
52 tors (FGFRs) are key signaling molecules for pancreas development.
58 omic-scale genetic and epigenetic studies of pancreas development and diseases such as diabetes and p
60 xpressed in the pancreas and is required for pancreas development and endocrine cell differentiation.
61 in that is a critical requirement for normal pancreas development and for proper differentiation of t
62 to the pancreas and foregut, is required for pancreas development and for the expression of genes con
63 n transcription factor IDX-1 is critical for pancreas development and for the regulation of islet cel
67 identify multiple sequential roles for Hh in pancreas development and highlight an unexpected antagon
68 iption factor IDX-1, a critical regulator of pancreas development and insulin gene transcription, con
69 ineate the role of Hh in zebrafish endocrine pancreas development and investigate its relationship wi
70 gene is expressed in endocrine cells during pancreas development and is essential for proper islet m
72 unique profile of miRNAs is required during pancreas development and is necessary for beta-cell form
73 es for transcription factors associated with pancreas development and islet cell function, we analyze
74 Expression of PDX, a critical regulator of pancreas development and islet differentiation, is resto
75 ssion of multiple genes related to endocrine pancreas development and islet function in these liver c
76 Pdx1 is a transcription factor required for pancreas development and lineage specification; however,
78 s and colonies, should also advance study of pancreas development and pancreatic progenitor cells.
79 Nkx6.1 paralog, Nkx6.2, is expressed during pancreas development and partially compensates for NKX6.
80 mbined requirements for Hhip and Ptch during pancreas development and point to a dose-dependent respo
81 duct, while Sox17 overexpression suppresses pancreas development and promotes ectopic biliary-like t
82 s underlying GATA4 and GATA6 function during pancreas development and provide a new mouse model to ch
83 that Hippo signaling plays a crucial role in pancreas development and provide novel routes to a bette
84 accurately recapitulates key steps of human pancreas development and provides a fast and reproducibl
85 that CTGF acts in an autocrine manner during pancreas development and suggest that CTGF has the poten
86 omeobox 1 (PDX-1) is absolutely required for pancreas development and the maintenance of islet beta-c
87 nscription factor IDX-1 that is critical for pancreas development and the transcriptional regulation
88 o some ambiguity as to the role of Hh during pancreas development and whether its function has comple
89 histone deacetylases (HDACs), HDACs mediate pancreas development, and aspects of pancreas developmen
90 mplicate new signaling pathways in endocrine pancreas development, and identified sets of known and n
91 ic hedgehog also affects zebrafish liver and pancreas development, and these effects occur in a recip
93 mediate pancreas development, and aspects of pancreas development are recapitulated during recovery o
94 in maturing hormone-expressing cells during pancreas development as well as in adult islet cells.
97 ing is not restricted to patterning in early pancreas development but also continues to signal in dif
99 have identified factors required for dorsal pancreas development, but factors that initiate the vent
100 has been shown to regulate early aspects of pancreas development, but its role in endocrine, and esp
101 in, a TGF(beta+) signaling molecule, permits pancreas development by repressing expression of Sonic h
102 orm of beta-catenin at a later time point in pancreas development causes enhanced proliferation that
103 nitor-specific ablation of Sox9 during early pancreas development causes pancreas-to-liver cell fate
105 biologically significant stages of endocrine pancreas development: endoderm before pancreas specifica
106 , we have compiled reference GRNs underlying pancreas development from data mining that integrates mu
108 vation of Hedgehog signaling at the onset of pancreas development has been shown to inhibit organ mor
109 larify the function of Hedgehog signaling in pancreas development, identify an unexpected cellular so
111 lude that NEUROG3 is essential for endocrine pancreas development in humans and that as little as 10%
113 h of data and comprehensive reviews exist on pancreas development in mammals, primarily mice, and oth
118 Here, we characterize zebrafish exocrine pancreas development in wild type and mutant larvae usin
120 1), a transcription factor indispensable for pancreas development, in the progression from normal exo
122 Here we describe systems for reconstructing pancreas development, including islet beta-cell and alph
123 in transcription factor Pdx1 is required for pancreas development, including the differentiation and
124 othelial growth factor (VEGF) is crucial for pancreas development, insulin gene expression/secretion,
126 elucidation of the key regulatory factors in pancreas development is critical for understanding the p
129 main transcription factor PDX1, required for pancreas development, is expressed broadly in the poster
130 al homeobox factor-1, PDX-1, is required for pancreas development, islet cell differentiation, and th
132 in contact with the posterior bud throughout pancreas development, its absence in cloche mutant embry
133 d receptor (GPCR) S1pr2, plays a key role in pancreas development linking lineage allocation and spec
135 pressed broadly in the posterior foregut but pancreas development normally initiates only in a restri
137 eam transcription factor E2f1 regulate mouse pancreas development prior to and during the secondary t
139 ent for native genetic regulators of in vivo pancreas development, such as Ngn3, Arx, and Pax4, revea
141 tify Cdk4 as an important regulator of early pancreas development that modulates the proliferation po
142 r, these data demonstrate that UCP2 controls pancreas development through the ROS-AKT signaling pathw
145 question, we first evaluated FoxO1's role in pancreas development using gain- and loss-of-function al
146 we examine the specific role of Hnf1b during pancreas development, using constitutive and inducible c
147 activate the Hedgehog pathway midway through pancreas development via expression of either Sonic (Shh
148 to understand the biology of p120 catenin in pancreas development, we ablated p120 catenin in mouse p
149 lished data from mouse embryos, during human pancreas development, we detected only a single-phase of
150 sequences of epithelial Hh activation during pancreas development, we employed a transgenic mouse mod
151 gate the influence of surrounding tissues on pancreas development, we examined the role of the vascul
152 pathway is functionally required for normal pancreas development, we have specifically deleted the b
154 derstanding of transcriptional regulation in pancreas development, we know relatively little about th
157 Discovering the function of genes regulating pancreas development with our system should enrich strat
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