ライフサイエンスコーパス: pancreatic ribonuclease

1 han to either murine angiogenin or to murine pancreatic ribonuclease.

2 a class of chemotherapeutic agents based on pancreatic ribonucleases.

3 ages of the oxidative folding of both bovine pancreatic ribonuclease A (RNase A) and a 58-72 fragment

4 The interactions between bovine pancreatic ribonuclease A (RNase A) and its RNA substrat

5 The interaction between bovine pancreatic ribonuclease A (RNase A) and its RNA substrat

6 is method to the oxidative folding of bovine pancreatic ribonuclease A (RNase A) and show that des[40

7 Bovine pancreatic ribonuclease A (RNase A) cleaves this substra

8 The dimer of bovine pancreatic ribonuclease A (RNase A) discovered by Crestf

9 It belongs to the bovine pancreatic ribonuclease A (RNase A) family and exhibits

10 athway of a three-disulfide mutant of bovine pancreatic ribonuclease A (RNase A) from the fully reduc

11 The regeneration of bovine pancreatic ribonuclease A (RNase A) from the reduced to

12 During the regeneration of bovine pancreatic ribonuclease A (RNase A) from the reduced to

13 Bovine pancreatic ribonuclease A (RNase A) has a conserved His

14 he major oxidative folding pathway of bovine pancreatic ribonuclease A (RNase A) has been examined at

15 0A, C95A] and [C65S, C72S] mutants of bovine pancreatic ribonuclease A (RNase A) have been studied.

16 nts (P42A, P93A, P114A, and P117A) of bovine pancreatic ribonuclease A (RNase A) in which each mutant

17 Bovine pancreatic ribonuclease A (RNase A) is a 124-residue enz

18 Bovine pancreatic ribonuclease A (RNase A) is a distributive en

19 The active-site cleft of bovine pancreatic ribonuclease A (RNase A) is lined with cation

20 ays of two three-disulfide mutants of bovine pancreatic ribonuclease A (RNase A) missing the 65-72 di

21 step in the oxidative regeneration of bovine pancreatic ribonuclease A (RNase A) proceeds through des

22 Select members of the bovine pancreatic ribonuclease A (RNase A) superfamily are pote

23 ase (ONC), an amphibian member of the bovine pancreatic ribonuclease A (RNase A) superfamily, is in p

24 c regions of the polypeptide chain of bovine pancreatic ribonuclease A (RNase A) that are critical fo

25 Mutants of bovine pancreatic ribonuclease A (RNase A) that contain four of

26 ent molecular dynamics simulations of bovine pancreatic ribonuclease A (RNase A) up to its melting te

27 adenosine 3'-phosphate (pTppAp) with bovine pancreatic ribonuclease A (RNase A) was characterized by

28 ous crystals (space group P3(2)21) of bovine pancreatic ribonuclease A (RNase A) were prepared at a p

29 Onconasetrade mark, a homolog of bovine pancreatic ribonuclease A (RNase A) with high conformati

30 nfolding of its structural homologue, bovine pancreatic ribonuclease A (RNase A), has been isolated a

31 uman angiogenin (Ang), a homologue of bovine pancreatic ribonuclease A (RNase A), is a potent inducer

32 Angiogenin (ANG), a homologue of bovine pancreatic ribonuclease A (RNase A), promotes the growth

33 In bovine pancreatic ribonuclease A (RNase A), the His...Asp dyad

34 sed to study the backbone dynamics of bovine pancreatic ribonuclease A (RNase A).

35 ency" present in reduced and unfolded bovine pancreatic ribonuclease A (RNase A).

36 ity are reviewed and illustrated with bovine pancreatic ribonuclease A (RNase A).

37 age/hydrolysis reactions catalyzed by bovine pancreatic ribonuclease A (RNase A).

38 he oxidative regeneration pathways of bovine pancreatic ribonuclease A (RNase A).

39 n peroxidase (LiP) was examined using bovine pancreatic ribonuclease A (RNase) as a polymeric lignin

40 ement during the refolding of reduced bovine pancreatic ribonuclease A (RNase).

41 asured for the nonspecific binding of bovine pancreatic ribonuclease A and Escherichia coli lac repre

42 e major oxidative folding pathways of bovine pancreatic ribonuclease A at pH 8.0 and 25 degrees C inv

43 efolding kinetics of disulfide-intact bovine pancreatic ribonuclease A by fluorescence-detected stopp

44 ediates in the oxidative refolding of bovine pancreatic ribonuclease A has been characterized.

45 ded species (Uvf) of disulfide-intact bovine pancreatic ribonuclease A has been monitored by circular

46 A variant of bovine pancreatic ribonuclease A has been prepared with seven a

47 ental, variable-pressure NMR data for bovine pancreatic ribonuclease A in 2H2O at pH 2.0 and 295 K yi

48 um unfolded state of disulfide-intact bovine pancreatic ribonuclease A is a heterogeneous mixture of

49 he unfolded state of disulfide-intact bovine pancreatic ribonuclease A is a heterogeneous mixture of

50 slow fluorescence unfolding phase of bovine pancreatic ribonuclease A is studied by stopped-flow kin

51 ing and unfolding of disulfide-intact bovine pancreatic ribonuclease A is used as an example to illus

52 Refolding intermediates of bovine pancreatic ribonuclease A, a model system for this study

53 2 to G, A, or L in the model protein, bovine pancreatic ribonuclease A, and through analysis of tempe

54 cturally well-characterized proteins (bovine pancreatic ribonuclease A, bovine pancreatic trypsin inh

55 inct, member of the angiogenin sub-family of pancreatic ribonucleases, and is referred to as angiogen

56 Bovine pancreatic ribonuclease B (RNase B) differs from RNase A

57 d zinc ions inhibit the oxidation of reduced pancreatic ribonuclease by the enzyme.

58 ity between two structural homologues of the pancreatic ribonuclease family: RNase A and eosinophil c

59 to address these questions in a study of the pancreatic ribonuclease gene (RNASE1) and its duplicate

60 d in an assay of a mutated form of the human pancreatic ribonuclease gene inserted into the plasmid p

61 onclude that the His...Asp catalytic dyad in pancreatic ribonucleases has two significant roles: (1)

62 Human pancreatic ribonuclease (hRNase) has high enzyme activit

63 , a highly conserved residue among mammalian pancreatic ribonucleases, lies atop the (40-95) disulfid

64 is...Asp dyad is conserved in all homologous pancreatic ribonucleases of known sequence.

65 Human pancreatic ribonuclease (RNase 1) is homologous to Oncon

66 Mounting evidence suggests that human pancreatic ribonuclease (RNase 1) plays important roles

67 To do so, we create variants of human pancreatic ribonuclease (RNase 1) that differ in net mol

68 interaction between human RI (hRI) and human pancreatic ribonuclease (RNase 1).

69 rate random mutations in the genes of bovine pancreatic ribonuclease (RNase A) and human angiogenin,

70 Onconase (ONC) is a homolog of bovine pancreatic ribonuclease (RNase A) from the frog Rana pip

71 protein (RI) binds to members of the bovine pancreatic ribonuclease (RNase A) superfamily with an af

72 an angiogenin (ANG) is a homologue of bovine pancreatic ribonuclease (RNase A) that induces neovascul

73 of fluorescein-labeled model protein, bovine pancreatic ribonuclease (RNase A), decreases upon bindin

74 nuclease (BS-RNase) is a homologue of bovine pancreatic ribonuclease (RNase A).

75 lic protein and a potent inhibitor of bovine pancreatic ribonuclease (RNase A).

76 st this notion, glycosylated forms of bovine pancreatic ribonuclease (RNase) were translated in the p

77 s of native and glycosylated forms of bovine pancreatic ribonuclease (RNase).

78 Pancreatic ribonuclease (RNASE1) is a digestive enzyme t

79 bonucleases into five distinct lineages--the pancreatic ribonucleases (RNases 1), the eosinophil-asso

80 fer dramatically among homologues within the pancreatic ribonuclease superfamily.

81 I report that the gene encoding pancreatic ribonuclease was duplicated independently in