ライフサイエンスコーパス: pannus

1 ion tissue with early fibrous encapsulation (pannus).

2 ents with 39 MDCT masses (22 thrombus and 17 pannus).

3 ected as tissue overgrowth was classified as pannus.

4 le patient showed a subepithelial, avascular pannus.

5 ns the aggressive phenotype of the advancing pannus.

6 he rheumatoid arthritis (RA) synovial tissue pannus.

7 l blood and accumulated in inflamed synovial pannus.

8 e suppression of the angiogenic component of pannus.

9 ght play a role in neovascularization of the pannus.

10 while FLIP remained highly expressed in the pannus.

11 ue and to the growth and proliferation of RA pannus.

12 ation found in the rheumatoid arthritic (RA) pannus.

13 r the chondrocytic cells found in rheumatoid pannus.

14 res of vascularity, villous hypertrophy, and pannus.

15 expanding inflammatory tissue referred to as pannus.

16 sses was significantly lower than that in 17 pannus (87+/-59 versus 322+/-122; P<0.001).

17 tified on cells at the invasive front of the pannus and at sites of cartilage erosion.

18 tis, especially at the interface of synovial pannus and eroding bone.

19 Although immune cells, which infiltrate the pannus and promote inflammation, play a prominent role i

20 l and subclinical inflammation, formation of pannus and synovial hyperplasia, and the erosion of cart

21 synovitis characterized by the formation of pannus and the destruction of cartilage and bone in the

22 Distinguishing pannus and thrombus in patients with prosthetic valve dy

23 tomography (MDCT) in distinguishing between pannus and thrombus, the latter amenable to thrombolysis

24 y, resulting in a dense vascularized corneal pannus, and eventually leading to visual impairment.

25 ich contributes to the formation of invasive pannus, and in neutrophil survival, which affects inflam

26 ation; failed: recurrent epithelial defects, pannus, and inflammation), phenotype of cells covering t

27 gnificant reduction in synovial hyperplasia, pannus, angiogenesis, inflammatory infiltration, bone an

28 Histology scores for inflammation, pannus, bone damage, and cartilage damage decreased in p

29 larization, which supports the growth of the pannus by supplying it with nutrients and oxygen.

30 nts showed that C3 deposition, inflammation, pannus, cartilage, and bone damage scores were all signi

31 MT1-MMP was highly expressed at the pannus-cartilage junction in RA joints.

32 number of apoptotic cells was present at the pannus-cartilage junction.

33 splanted on the patient's affected eye after pannus excision.

34 g cells and fibroblast-like cells within the pannus expressed both PTHrP and the PTH/PTHrP receptor,

35 nts in TSG-6-treated animals revealed little pannus formation and cartilage erosion, features which w

36 nts showed that DMH-11C treatment attenuated pannus formation and joint tissue injury.

37 parameters that differentiate thrombus from pannus formation as the etiology of obstructed mechanica

38 In the CLAU group, a localized pannus formation at the donor site of the limbal graft w

39 in the rampant fibroblast proliferation and pannus formation characteristic of rheumatoid arthritis.

40 ical prosthetic valve can help differentiate pannus formation from thrombus and may therefore be of v

41 its receptor in fibroblast proliferation and pannus formation in RA.

42 Pannus formation was more common in the aortic position

43 rophy and hyperplasia, and highly aggressive pannus formation with erosion of the articular cartilage

44 The changes included synovial invasion (pannus formation) of the enthesis.

45 reduced the inflammatory cell infiltration, pannus formation, and bone and cartilage degradation.

46 lammatory cell infiltrate, cartilage damage, pannus formation, and bone damage.

47 arthritis, characterized by tissue swelling, pannus formation, and bone deformities.

48 e, inflammatory cell infiltration, fibrosis, pannus formation, and bone erosion in joints of BLT1/BLT

49 enesis and reduced synovial cell infiltrate, pannus formation, and cartilage erosions.

50 and bone erosions, synovial hyperplasia, and pannus formation, and reduced numbers of vessels (angiog

51 ptosis, proinflammatory cytokine expression, pannus formation, bone erosion, joint swelling, and pain

52 eases in the inflammatory cell infiltration, pannus formation, cartilage and bone destruction, and th

53 This leads to pannus formation, cartilage breakdown, and eventual bone

54 Scores for inflammation, pannus formation, cartilage damage, and bone resorption

55 -induced arthritis (CIA) is characterized by pannus formation, cell infiltration, and cartilage erosi

56 eficient mice revealed synovial hyperplasia, pannus formation, mononuclear cell infiltration, bone er

57 edema, fibrosis, epithelial downgrowths, and pannus formation.

58 Fourteen valves had thrombus and 10 had pannus formation.

59 peration of <1 month separated thrombus from pannus formation.

60 re performed on a corneal button and corneal pannus from 2 EEC patients.

61 %) and specificity (95.5%) in discriminating pannus from thrombus.

62 Features of vascularity, villous formation, pannus, granularity, and capillary hyperemia were record

63 on the valve in 92% of cases, whereas 29% of pannuses had a soft echo density (p= 0.007).

64 Cia5d) rats preserved a normal joint without pannus, hyperplasia, or erosions.

65 thrombosis in 3 (7%), mismatch in 2 (5%) and pannus in 1 (2%).

66 The cause of mechanical AVR obstruction was pannus in 26 cases (53%), mismatch (P-PM) in 19 (39%) an

67 ve cellular infiltration and fully developed pannus in arthritic joints of non-GTP-fed mice.

68 Tissue sections from the bone-pannus interface at sites of bone erosion were examined

69 Focal resorption of bone at the bone-pannus interface is common in rheumatoid arthritis (RA)

70 d arthritis (RA) is invasion of the synovial pannus into cartilage, and this process requires degrada

71 gressive growth and invasion of the synovial pannus into the surrounding cartilage and bone.

72 invasion and its associated joint damage and pannus invasion and destruction in RA.

73 ike synoviocyte (FLS), has a central role in pannus invasion and destruction of cartilage and bone in

74 tilage may be one of the factors that impede pannus invasion following an inflammatory insult to the

75 sential collagen-degrading proteinase during pannus invasion in human RA.

76 d in bone marrow in and adjacent to areas of pannus invasion in RA erosions.

77 ified in bone resorption lacunae in areas of pannus invasion into bone in RA patients.

78 t precursor cells are identified in areas of pannus invasion into bone in RA.

79 damage at sites adjacent to and distal from pannus invasion, and tartrate-resistant acid phosphatase

80 rophils, destruction of articular cartilage, pannus invasion, bone resorption, extra-articular fibrop

81 , membrane type 1 MMP (MT1-MMP), in synovial pannus invasiveness.

82 The expansion of pannus is supported by extensive formation of new blood

83 A major cellular component of the pannus is the fibroblast-like synoviocyte (FLS), whose m

84 undantly expressed in cells at the cartilage-pannus junction in rheumatoid synovitis.

85 ive to new blood vessel formation, and hence pannus mass, adding to other therapeutic effects of anti

86 ll-thickness expression of K19 in the entire pannus of all eight specimens.

87 ogic verification of LSCD, the fibrovascular pannus of each cornea was removed.

88 n the pathogenic processes that arise in the pannus of rheumatoid arthritis and also interfere with c

89 ntation, pump surfaces become covered with a pannus of smooth muscle-like cells (myofibroblasts).

90 Distinction of thrombus from pannus on obstructed prosthetic valves is essential beca

91 ical AVR obstruction, TEE differentiation of pannus or thrombus from mismatch is challenging.

92 iography in detecting the obstruction cause (pannus or thrombus), bioprosthesis calcifications, and e

93 rosion, bone erosion, and fibroproliferative pannus) or frozen, cryosectioned, and assayed for enzyme

94 A high (HU>/=145) attenuation suggests pannus overgrowth, whereas a lower value is associated w

95 ases with thrombus formation but in 60% with pannus (p=0.0198).

96 MP activity over TIMP action in the invading pannus, periarticular tissue, or SF.

97 age of origin of the entire conjunctivalized pannus removed from eight corneas with a diagnosis of to

98 er of neutrophils in the synovial lining and pannus significantly decreased from day 28 to day 35, su

99 In culture, all five pannus specimens generated a compact, small epithelial c

100 thelial outgrowth from segments of five such pannus specimens were analyzed by Western blot and rever

101 mbal epithelial explant, but not in all five pannus specimens.

102 ssed in the control specimen and in all five pannus specimens.

103 at sites of erosion and was localized to the pannus starting on day 21.

104 f extracellular matrix (ECM) proteins in the pannus suggest that intracellular signals generated thro

105 f an aggressive, tumor-like structure called pannus that erodes the joint.

106 ce studies showed that, aside from the joint pannus, the subchondral bone tissue constitutes an essen

107 The mechanism (pannus/thrombus vs. mismatch) was identified in 10% by T

108 s in vitro and also promote joint erosion by pannus tissue in vivo.

109 The resultant epithelial phenotype of the pannus tissue was not corneal, as evidenced by the negat

110 mity to MNCs, and in occasional cells within pannus tissue, but not in the MNCs in bone resorption la

111 Thrombi were larger than pannuses (total length 2.8+/-2.47 cm vs. 1.17+/-0.43 cm;

112 e 6 historical controls that developed LSCD, pannus was noted in 1 (13%) and pseudopterygium extendin

113 sion and localization of MT1-MMP in human RA pannus were investigated by Western blot analysis of pri

114 is characterized by an inflammatory synovial pannus which mediates tissue destruction.

115 ke expansion of inflamed synovial tissue, or pannus, which causes much of the joint damage in this di

116 for example, underlies the formation of the pannus, while proliferation of endothelial cells results

117 ignificant findings included the presence of pannus without inflammatory changes in the regions in wh