ライフサイエンスコーパス: paraben

1 , lotion (BP-3 and parabens), and cosmetics (parabens).

2 08 (2005-2008 for analyses of phthalates and parabens).

3 us 24 hr had higher concentrations of propyl paraben.

4 enol A to a high of > 180,000 ppm for methyl paraben.

5 elatively low for BPA to moderate for propyl paraben.

6 ng and added a preservative containing ethyl paraben.

7 , antioxidants, UV filters, musks, PBDEs and parabens.

8 cal significance for some LMW phthalates and parabens.

9 ctrophoresis (CE) for the extraction of four parabens.

10 e sum of parabens (methyl, ethyl, and propyl parabens), 2,5-dichlorophenol, and triclosan.

11 ary concentrations of five phenols and three parabens: 2,4-dichlorophenol (24-DCP), 2,5-dichloropheno

12 mong the four countries studied, the EDIs of parabens (5.4 ng/kg-bw/day) and BADGEs (6.5 ng/kg-bw/day

13 The removal efficiencies for parabens (89.6-99.9%) were higher than those for their m

14 The effects of HER ligands on paraben activation of c-Myc expression and cell prolifer

15 was observed in patch-clamp experiments with parabens added from either the cytoplasmic or periplasmi

16 Parabens (alkyl esters of p-hydroxybenzoic acid) are wid

17 Concentrations of parabens also were determined in sewage sludge collected

18 th lower concentrations of propyl and methyl parabens among men.

19 tions were found among the concentrations of paraben analogues in sediment and sludge, which suggeste

20 In this study, six paraben analogues, methyl- (MeP), ethyl- (EtP), propyl-

21 with altered respiratory health, with ethyl-paraben and bisphenol A exhibiting some consistency acro

22 In this study, six parabens and four common metabolites of parabens were me

23 Parabens and human epidermal growth factor receptor liga

24 Human exposure to parabens and other antimicrobial chemicals is continual

25 entrations of 11 target chemicals, viz., six parabens and their common hydrolysis product, 4-hydroxyb

26 le is known about the occurrence and fate of parabens and their metabolites in wastewater treatment p

27 The environmental emission of parabens and their metabolites through WWTP discharges w

28 The respective mass loadings of parabens and their metabolites were 46.3 and 6210 mg/d/1

29 ls, including phthalates and phenols such as parabens and triclosan, is ubiquitous within the U.S. ge

30 p-Hydroxybenzoic acid esters (parabens) and bisphenol A diglycidyl ether (BADGE) are w

31 ap (TCS), sunscreen (BP-3), lotion (BP-3 and parabens), and cosmetics (parabens).

32 emical combination (2-phenoxyethanol, methyl paraben, and ethyl paraben) appears in 1,059 products.

33 ed total and free BPA, butyl paraben, propyl paraben, and methyl paraben in 100% of samples, total be

34 Reducing phthalate, paraben, and phenol exposure from personal care products

35 Triclosan, methyl paraben, and propyl paraben concentrations were quantifi

36 s of biomarkers of diethyl phthalate, methyl paraben, and triclosan in rats.

37 e is documented widespread human exposure to parabens, and some experimental data suggest that they a

38 mples contained measurable concentrations of parabens, and the total concentrations (Sigmaparabens; s

39 ophenone-3; propyl, methyl, butyl, and ethyl parabens; and specific IgE levels were available for 860

40 (2-phenoxyethanol, methyl paraben, and ethyl paraben) appears in 1,059 products.

41 Despite evidence of estrogenicity, parabens are among the most widely used xenoestrogens in

42 Parabens are broad-spectrum antimicrobial preservatives

43 Parabens are common preservatives and environmental horm

44 Parabens are esters of p-hydroxybenzoic acid and are wid

45 The parabens are extracted from the samples using SPME, and

46 Parabens are preservatives commonly used in personal car

47 Parabens are suspected endocrine disruptors and ubiquito

48 p-Hydroxybenzoic acid esters (parabens) are amphipathic compounds widely used as food

49 ysis of the samples by SPME-IMS using benzyl paraben as an internal standard yields good comparison t

50 ), bisphenol A (BPA), triclosan (TCS), butyl paraben (B-PB), methyl paraben (M-PB), and propyl parabe

51 henol, butyl paraben, methyl paraben, propyl paraben, benzophenone-3, bisphenol A, and triclosan in u

52 phthalate metabolites and nine phenols (four parabens, benzophenone-3, BPA, two dichlorophenols, tric

53 We sought to measure phenol and paraben biomarker concentrations for the Norwegian Mothe

54 Ethyl-paraben, bisphenol A, 2,5-dichlorophenol, and DIDP tende

55 The compounds that contain a phenolic ring (parabens, bisphenol A, and triclosan) were completely tr

56 Other exposures (total parabens, bisphenol A, triclosan, benzophenone-3, total

57 hat cytoplasmically presented ethyl or butyl parabens both hasten the process of desensitization of M

58 tions of methyl (MP), propyl (PP), and butyl paraben (BP) among couples from a fertility center.

59 MeP), ethyl- (EtP), propyl- (PrP), and butyl parabens (BuP) were on the order of 1000 mug per gram of

60 ruits, and vegetables, and analyzed for five parabens by high-performance liquid chromatography-tande

61 The EDI values of total parabens (calculated from the mean concentrations measur

62 estigated the hypothesis that the potency of parabens can be increased with HER ligands, such as here

63 24 h had significantly higher geometric mean paraben concentrations (80-110%) in their urine than wom

64 n models to estimate associations of urinary paraben concentrations (in tertiles) with ovarian reserv

65 Paraben concentrations [methylparaben (MP), propylparabe

66 There were no significant differences in paraben concentrations among the eight food categories,

67 between prenatal and early-life triclosan or paraben concentrations and childhood asthma, recurrent w

68 ere fit to examine demographic predictors of paraben concentrations and to calculate intraclass corre

69 Methyl and propyl paraben concentrations decreased by 43.9% (95% CI: -61.3

70 tal sensitization associated with increasing paraben concentrations in male compared with female subj

71 xpectedly, concentrations of ethyl and butyl paraben concentrations increased, although concentration

72 Among 129 pregnant women, urinary paraben concentrations were 25-45% lower during pregnanc

73 Urinary paraben concentrations were more variable in women compa

74 Triclosan, methyl paraben, and propyl paraben concentrations were quantified in maternal plasm

75 maternal plasma or child urine triclosan or paraben concentrations with asthma or recurrent wheeze o

76 We examined the association of urinary paraben concentrations with markers of ovarian reserve i

77 luated predictors and variability of urinary paraben concentrations.

78 d predicted a 254-1,333% increase in MEP and parabens concentrations.

79 allowed us to identify likely BPA and butyl paraben contamination of archived MoBa urine specimens.

80 investigate any possible external phenol or paraben contamination of specimens.

81 However, previous cell-based studies with parabens do not take into account the signaling cross-ta

82 lar associations were observed between ethyl paraben (EP) and couple fecundity for both partner and c

83 The regression equations of these parabens exhibited good linearity (r(2)=0.998, 0.1-10mug

84 an inverse association between triclosan and paraben exposure and allergic sensitization was observed

85 etween prenatal and early-life triclosan and paraben exposure and childhood allergic disease in a pro

86 odestly increased internal LMW phthalate and paraben exposure in 4-9 year old children.

87 The differential effects of triclosan or paraben exposure on allergic sensitization by sex observ

88 e reproductive health effects in relation to paraben exposure.

89 reclude possible adverse effects of paternal paraben exposures on such outcomes, given the modest sam

90 assisted cloud point extraction (SA-CPE) for paraben extraction.

91 iciencies, and environmental emission of six parabens, four of their metabolites (4-hydroxy benzoate,

92 Back-extraction of parabens from chloroform into a 50mM sodium hydroxide so

93 nique was better suited to the extraction of parabens from complex matrices.

94 In contrast, dermal intake of parabens from PCPs by infants and toddlers was higher th

95 Widespread exposure of humans to parabens has raised significant public health concerns.

96 PrP), butyl- (BuP), benzyl-(BzP), and heptyl parabens (HepP), were determined in surface sediment and

97 PCPs) are exposure sources to phthalates and parabens; however, their contribution to men's exposure

98 A, butyl paraben, propyl paraben, and methyl paraben in 100% of samples, total benzophenone-3 in 95%

99 were modified successfully to determine four parabens in 19 commercial products.

100 nd within-person variability for phenols and parabens in a MoBa sample (n = 45), including a subgroup

101 chlorophenol, 2,5- dichlorophenol, and three parabens in at least 60% of the pools suggesting childre

102 ot consistently associated with TCS or total parabens in children or adolescents of either sex.

103 concentrations of phthalate metabolites and parabens in Danish children.

104 Concentrations of sum of six parabens in dust were on the order of several hundred to

105 Information on the occurrence of parabens in foodstuffs and dietary exposure of humans to

106 the first study to report the occurrence of parabens in foodstuffs.

107 le and rapid method for the determination of parabens in human milk and food with relative recoveries

108 ducts (BADGEs) in indoor dust samples and of parabens in indoor dust from Asian countries.

109 and quartiles of urinary BPA, BP-3, TCS, and parabens in male and female children (ages 6-11 years) a

110 s, little is known about the accumulation of parabens in marine organisms.

111 concentrations of phthalate metabolites and parabens in men.

112 spite the widespread usage of phthalates and parabens in personal care products (PCPs), little is kno

113 Vertical profiles of parabens in sediment cores from the U.S. showed a gradua

114 Thus, the determination of parabens in such products is of particular importance.

115 ern, little is known about the occurrence of parabens in the environment.

116 es but may not be the primary target for the parabens in their antimicrobial activity.

117 No studies have assessed the variability of parabens in women, including during pregnancy.

118 of parabens (methyl, ethyl, propyl and butyl paraben) in different samples (food, cosmetics and water

119 chemicals (i.e., benzophenone-3, triclosan, parabens) in human urine, milk, and serum to identify po

120 phenol A, benzophenone-3, and triclosan) and parabens is widespread in the population.

121 posure to phenols, including bisphenol A and parabens, is widespread.

122 nt of the sum of six parent parabens (Sigma6 Parabens) leached from teethers ranged from 2.0 to 1990

123 bisphenol A, benzophenone-3, triclosan, and paraben levels in male and female children and adolescen

124 Phthalate metabolite and paraben levels were generally higher in children with fr

125 In this group are common parabens, lower molecular weight phthalates, o-phenylphe

126 riclosan (TCS), butyl paraben (B-PB), methyl paraben (M-PB), and propyl paraben (P-PB).

127 Parabens may be added to cosmetic and personal care prod

128 Exposures to environmental phenols and parabens may be harmful, especially in utero.

129 All parabens measured in maternal urine had moderate to high

130 Methyl paraben (MeP) was the predominant compound found in the

131 Methyl paraben (MeP), propyl paraben (PrP), BADGE.2H(2)O, and B

132 droxybenzoic acid (4-HB) was the predominant paraben metabolite found in all tissue samples.

133 ens (Sigmaparabens = 6 parent compounds) and paraben-metabolites (Sigmametabolites = 4 metabolites) w

134 ein, benzophenone-3, bisphenol A, the sum of parabens (methyl, ethyl, and propyl parabens), 2,5-dichl

135 oposed for the quantitative determination of parabens (methyl, ethyl, propyl and butyl paraben) in di

136 ,4-dichlorophenol, 2,5-dichlorophenol, butyl paraben, methyl paraben, propyl paraben, benzophenone-3,

137 ration in vitro via ERalpha, suggesting that parabens might be active at exposure levels not previous

138 ommon allergens were fragrance mix (n = 87), paraben mix (n = 75), and tocopherol (n = 74).

139 he highest quartile of female urinary methyl paraben (MP) concentrations relative to the lowest refle

140 ingredients [diethyl phthalate (DEP), methyl paraben (MPB), and triclosan] and urine and serum concen

141 Increasing concentrations of parabens on the cytoplasmic side of excised patches shif

142 describe effects of ethyl, propyl, and butyl parabens on the gating of the bacterial mechanosensitive

143 en (B-PB), methyl paraben (M-PB), and propyl paraben (P-PB).

144 icrobial EDCs triclosan and propyl and butyl parabens (P </= .04).

145 Parabens (p-hydroxybenzoic acid esters), bisphenols, ben

146 eriments suggested that the more hydrophobic parabens partition more strongly into the lipid and exer

147 compared with the lowest quartile of methyl paraben, paternal concentrations in the second quartile

148 thalate esters (PEs), bisphenol A (BPA), and parabens (PBs), which are used in numerous consumer prod

149 Analytes included parabens, phthalates, bisphenol A (BPA), triclosan, etha

150 Laboratory animal studies have shown that parabens possess weak estrogenic activity.

151 pressure of 35 mN/m, ethyl, propyl, or butyl paraben present in the subphase at 1 mM increased the su

152 The widespread exposure of humans to parabens present in personal care products is well-known

153 We detected total and free BPA, butyl paraben, propyl paraben, and methyl paraben in 100% of s

154 l, 2,5-dichlorophenol, butyl paraben, methyl paraben, propyl paraben, benzophenone-3, bisphenol A, an

155 Methyl paraben (MeP), propyl paraben (PrP), BADGE.2H(2)O, and BADGE.HCl.H(2)O were th

156 f their four transformation products (Sigma4 Parabens) ranged from 0.47 to 839 ng.

157 l concentrations (Sigmaparabens; sum of five parabens) ranged from below the limit of quantitation to

158 37 and 31.0 mug/kg-bw/day for phthalates and parabens, respectively, for adult females.

159 urinary levels of one LMW phthalate and two parabens, respectively, when compared to children withou

160 The total amount of the sum of six parent parabens (Sigma6 Parabens) leached from teethers ranged

161 e median respective concentrations of sum of parabens (Sigmaparabens = 6 parent compounds) and parabe

162 We present evidence that paraben/sorbate induction of EPA6 expression involves bo

163 Neither of the parabens strongly affects the rate of recovery and does

164 To achieve this, the paraben substituted cyclotetraphosphazene compounds have

165 The sum concentrations of six parabens ( summation operatorPBs) in sludge (geometric m

166 are an important source of human exposure to parabens; the contribution of PCPs to phthalate exposure

167 ake (EDI; ng/kg of body weight (bw)/day)) of parabens through food ingestion.

168 onception urinary chemical concentrations of parabens, triclosan and triclorcarban in relation to TTP

169 ine-disrupting chemicals such as phthalates, parabens, triclosan, and benzophenone-3 (BP-3) for adole

170 les were analyzed for phthalate metabolites, parabens, triclosan, and BP-3 using high-performance liq

171 s that are labeled to be free of phthalates, parabens, triclosan, and BP-3, can reduce personal expos

172 In cross-sectional studies triclosan and parabens, ubiquitous ingredients in personal care and ot

173 des under ion-exchange conditions and propyl paraben under reversed-phase conditions.

174 urine collection strongly predicted MEP and paraben urinary concentrations.

175 The EDIs of parabens via dust ingestion were 5-10 times higher in ch

176 Ethyl-paraben was associated with increased asthma rate [hazar

177 n contrast, the largest percent increase for parabens was associated with the use of suntan/sunblock

178 , theoretical plates, and drift times of the parabens were also evaluated based on the direct interfa

179 These parabens were also measured in breast milk samples colle

180 In this study, nine phthalates and six parabens were determined in 170 PCPs (41 rinse-off and 1

181 concentrations of phthalate metabolites and parabens were determined, and children were genotyped fo

182 Parabens were found in approximately 40% of rinse-off pr

183 Increases in MEP and parabens were generally greater with PCP use within 6 h

184 Butyl- and benzyl-parabens were less frequently detected.

185 six parabens and four common metabolites of parabens were measured in 121 tissue samples from eight

186 vels of the antimicrobial EDCs triclosan and parabens were significantly associated with allergic sen

187 on, while concentrations of BPA, 24-DCP, and parabens were similar.

188 Methyl-, ethyl-, and propyl-parabens were the predominant compounds, accounting for

189 ermal intake doses (sum of all phthalates or parabens) were calculated to be 0.37 and 31.0 mug/kg-bw/

190 benzophenone-3 (BP-3), triclosan (TCS), and parabens with serum total testosterone (TT) levels in ch