ライフサイエンスコーパス: paracetamol

1 sumed a 200-mL liquid meal (400 kcal + 1.5 g paracetamol).

2 gested an increased risk with acetaminophen (paracetamol).

3 rkers to stratify patients who overdose with paracetamol.

4 on the voltammetric response of caffeine and paracetamol.

5 3) were 0.79muM for caffeine and 0.45muM for paracetamol.

6 chemically generated reactive metabolites of paracetamol.

7 ompaction behavior of the monoclinic form of paracetamol.

8 ds, nonsteroidal anti-inflammatory drugs and paracetamol.

9 g from drug-induced liver injury, often from paracetamol.

10 ent; and N-acetyl-para-aminophenol (APAP, or paracetamol), a hepatotoxic analgesic drug.

11 ter-sized crystals of the monoclinic form of paracetamol-a widely used analgesic known for its partic

12 nd environmental influences, with a study of paracetamol (acetaminophen) administered to rats.

13 n the identification of batches of analgesic paracetamol (acetaminophen) tablets using nitrogen-14 nu

14 ntly associated with being female and taking paracetamol (acetaminophen).

15 o xenobiotic-derived substructures including paracetamol/acetaminophen mercapturate and dimethylpyrog

16 d the extent of liver damage sustained after paracetamol administration.

17 recovery area, all patients received 1000 mg paracetamol and 50 mg diclofenac, orally, to be continue

18 disruptor as reported for fellow analgesics paracetamol and aspirin.

19 uterine and ovarian atrophy at high doses of paracetamol and decreased ovarian-cyst formation at lowe

20 were performed with ascorbic acid, dopamine, paracetamol and epinephrine.

21 Tablets of paracetamol and hyproxypropyl methylcellulose (HPMC) and

22 ommonly interfering compounds such as urate, paracetamol and l-ascorbate.

23 All patients had access to paracetamol and metoclopramide.

24 nti-inflammatory drugs such as acetaminophen/paracetamol and nonsteroidal anti-inflammatory drugs (NS

25 f-reported prescribing of both acetaminophen/paracetamol and opiates in 97% of patients and gabapenti

26 Paracetamol (APAP) has been known to induce hepatotoxici

27 mol/kg), diethyl maleate (DEM; 4.2 mmol/kg), paracetamol (APAP; 3.5 and 1.0 mmol/kg), or carbon tetra

28 nd systemic administration of acetaminophen (paracetamol) are lost in Trpa1(-/-) mice.

29 racetamol or Co-dydramol (dihydrocodeine and paracetamol) as required; they completed linear analogue

30 replacement therapy, statins, acetaminophen/paracetamol, aspirin, tea drinking, history of general a

31 Certain fragments (including paracetamol) bind in a consistent mode to different brom

32 , sugar, acetylsalicylic acid (aspirin), and paracetamol-caffeine-based analgesic drugs.

33 nt (n = 53), stratified according to whether paracetamol caused ALF.

34 ing of several other analgesics (co-codamol, paracetamol, codeine, co-dydramol, tramadol, oxycodone,

35 ostoperative use of intermittent intravenous paracetamol compared with continuous morphine resulted i

36 The analgesic co-proxamol (paracetamol/dextropropoxyphene combination) has been wid

37 e status of 170 women with self-administered paracetamol-diclofenac with or without TAP blocks.

38 nents to allow the probe to melt through the paracetamol down to the underlying HPMC.

39 (interquartile range, 99-264) mug/kg in the paracetamol group (n = 33) and 357 (interquartile range,

40 that was 66% (95% CI, 34%-109%) lower in the paracetamol group.

41 ntial hepatotoxicity of therapeutic doses of paracetamol have been highlighted in the last 18 months.

42 rmaceutical ingredients, including caffeine, paracetamol, ibuprofen, tamoxifen, BAY 11-7082 and fluor

43 0-125muM were obtained for both caffeine and paracetamol in acetate buffer solution of pH 4.5 with a

44 has prompted a reassessment of the safety of paracetamol in certain groups of patients.

45 e quantitative determination of caffeine and paracetamol in Coca-Cola, Pepsi-Cola and tea samples.

46 rognostic model of outcome for patients with paracetamol induced acute liver injury based on admissio

47 patients suffering from acetaminophen (APAP, paracetamol)-induced acute liver failure (ALF) showed si

48 Acetaminophen (APAP, paracetamol)-induced hepatotoxicity, although treatable

49 njury in the context of acetaminophen (APAP; paracetamol)-induced liver injury is an important predic

50 spective initial sample of 103 patients with paracetamol-induced acute liver failure and applied to a

51 teria for emergency liver transplantation in paracetamol-induced acute liver failure are widely used,

52 Patients with paracetamol-induced acute liver failure managed at inten

53 tions for emergency liver transplantation in paracetamol-induced acute liver failure require re-evalu

54 al is central to management of patients with paracetamol-induced acute liver failure to identify thos

55 to support decision making in patients with paracetamol-induced acute liver failure.

56 rately identifies patients who will die from paracetamol-induced acute liver failure.

57 ong paracetamol-induced ALF; 79.4% among non-paracetamol-induced ALF) (P < 0.001).

58 02 patients had transplantation (41.0% among paracetamol-induced ALF; 79.4% among non-paracetamol-ind

59 New Zealand ICUs suggest that acetaminophen/paracetamol is the most common first-line analgesic (49.

60 Acetaminophen (paracetamol) is a widely used analgesic and antipyretic

61 Acetaminophen (paracetamol) is the most commonly used medication for pa

62 Acetaminophen (paracetamol) is the most frequently used analgesic and a

63 Importance: Acetaminophen (paracetamol) is used by a large proportion of pregnant w

64 combination of ibuprofen and acetaminophen (paracetamol) may represent a viable nonopioid alternativ

65 the thermodynamic stability among competing paracetamol molecular crystal polymorphs.

66 A typical anti-pain/fever drug paracetamol often causes hepatotoxicity due to peroxynit

67 receptor antagonist (ranitidine), analgesic (paracetamol), opiate (codeine), and aromatase inhibitor

68 Patients took paracetamol or Co-dydramol (dihydrocodeine and paracetam

69 Acetaminophen (APAP; ie, Paracetamol or Tylenol) is generally self-medicated to t

70 cytotoxic model compounds (sodium azide and paracetamol) or subjected to freeze-thaw cycles to induc

71 el is able to identify patients who die from paracetamol overdose fulminant hepatic failure as accura

72 ded intravenous acetylcysteine treatment for paracetamol overdose had circulating biomarkers measured

73 Paracetamol overdose is common but patient stratificatio

74 We randomly allocated patients with acute paracetamol overdose to either the standard intravenous

75 ts who required acetylcysteine treatment for paracetamol overdose were recruited (985 in the MAPP coh

76 nts transplanted for other causes of FHF (11 paracetamol overdose, 2 idiosyncratic drug reaction, 3 W

77 /=16 years in Scotland), were diagnosed with paracetamol overdose, and gave written informed consent.

78 phate (COD) determination in the presence of paracetamol (PAR) and caffeine (CAF).

79 Paracetamol poisoning is common worldwide.

80 In patients with paracetamol poisoning, a 12 h modified acetylcysteine re

81 Acetaminophen (APAP, paracetamol) poisoning is a leading cause of acute liver

82 t molecular ion for each drug (theophylline, paracetamol, prednisolone) showed their distribution ran

83 In patients with paracetamol-related ALF, the 6-month survival rate was 6

84 rkedly differing thermal responses, with the paracetamol showing a sharp melting accompanied by a pro

85 hylline, caffeine, ibuprofen, acetaminophen (paracetamol), sulindac and indomethacin, was also achiev

86 crimination between the different batches of paracetamol tablets.

87 n (as trihydrate) and the analgesic medicine Paracetamol, that the latter design gives NQR signal int

88 tinuous morphine or intermittent intravenous paracetamol up to 48 hours postsurgery.

89 ally significant inverse association between paracetamol use and ovarian cancer risk.

90 r simultaneous determination of caffeine and paracetamol using square-wave voltammetry.

91 ibuprofen was 1.03 (0.64-1.64), and that for paracetamol was 0.52 (0.31-0.86), after adjusting for ag

92 Acute liver failure not caused by paracetamol was associated with greater 6-month patient

93 chemically generated reactive metabolites of paracetamol was mimicked by their adduct formation with

94 lower risk of ovarian cancer associated with paracetamol was more apparent for use on a daily basis,

95 stances in the determination of caffeine and paracetamol were also studied and their interferences we

96 Glucose, sulfathiazole, and paracetamol were impregnated with bis-nitroxide biradica