ライフサイエンスコーパス: paradoxically

1 Paradoxically, 19S proteasome regulator knockdown induce

2 gated indefinitely in vitro, pluripotency is paradoxically a transient state in vivo, lasting 2-3 day

3 Paradoxically, a concurrent activation of spontaneous tu

4 Paradoxically, a significant number of patients with suc

5 Paradoxically, a specially engineered interaction with t

6 Paradoxically, abuse-associated cues seem to acquire pow

7 in response to alcohol, increased claudin-5 paradoxically accompanies an increase in paracellular le

8 se that dyslexics' shorter neural adaptation paradoxically accounts for their longer reading times, s

9 etitive RAF inhibitors can either inhibit or paradoxically activate the MAPK pathway, depending wheth

10 e turnover; however, chemical RAF inhibitors paradoxically activate the pathway, promoting epidermal

11 We propose that paradoxically activated MAFs provide a "safe haven" for

12 In contrast, unliganded PRA paradoxically activates Cx43 transcription by interactin

13 In tumors with wild-type B-Raf, vemurafenib paradoxically activates downstream signaling and cell pr

14 aling in cancers harboring mutant B-Raf, but paradoxically activates MEK/ERK in Ras-mutated cancers.

15 IPA also inhibits PERK but, paradoxically, activates it at low concentrations, resul

16 already show large interfacial stresses and, paradoxically, adding surfactants yields barely measurab

17 Paradoxically, AE3 enhances intracellular re-alkalizatio

18 Paradoxically, agonists at ERalpha such as estradiol (E2

19 Paradoxically, alcohol acts as both a stimulant and a se

20 However, paradoxically, alloreactivity can proceed with high pept

21 der antithrombin-dependent FXa inactivation, paradoxically allowing uninhibited FXa to persist in pla

22 Paradoxically, alpha-tocopherol remained in circulation

23 IFN regulatory factor (IRF)4 and Blimp1, and paradoxically also activation-induced deaminase (AID) in

24 2 competes with ANG1 to inhibit Tie2, it can paradoxically also promote Tie2 phosphorylation (p-Tie2)

25 omotes body weight reduction in humans while paradoxically also promoting insulin resistance (IR) and

26 Paradoxically, although D145E C-domain was unable to bin

27 Even more paradoxically, an extra copy of the genome is better tol

28 generated by a rarefied atmosphere, they are paradoxically analogous to ripples emerging on granular

29 Paradoxically, analysis of cells resistant to DNA damagi

30 Paradoxically, antiretroviral therapy (ART) worsens bone

31 Paradoxically, aPKC also phosphorylates Par3/Baz, provok

32 freeze-avoiding insects in winter, and yet, paradoxically are found in some freeze-tolerant insects.

33 High body mass index (BMI) is paradoxically associated with better outcome in hemodial

34 culosis that was FDA microscopy negative was paradoxically associated with greater infectiousness.

35 r disease and progression to fibrosis but is paradoxically associated with lower levels of hepaticall

36 tration rate (eGFR), such that higher CI was paradoxically associated with worse eGFR (r = -0.12; p =

37 Paradoxically, at the originally proposed cell-type leve

38 ed to monitoring and improving behavior can, paradoxically, at times be the source of performance fai

39 Paradoxically, ATR inhibits CDKs during checkpoint respo

40 r between groups, and glucagon secretion was paradoxically augmented after RYGB.

41 ual similarity), hippocampal representations paradoxically became relatively more similar.

42 Paradoxically, because of their potential to cause death

43 nto how to analyze and treat these data may, paradoxically, become more important.

44 % confidence interval):1.04 (1.03-1.06)] and paradoxically better outcomes among Hispanic adults [0.8

45 mpair glucose-induced insulin secretion and, paradoxically but characteristically, are associated wit

46 Paradoxically, by increasing chemoresistance and cancer

47 few and recurrent molecular aberrations but, paradoxically, can have variable natural histories.

48 cally thought to permit low firing rates can paradoxically cause a jump to a high minimum firing rate

49 I, but nonmuscle myosin-IIA (MIIA) mutations paradoxically cause MYH9-related diseases (MYH9-RD) that

50 ate transitions, while adaptation in E cells paradoxically caused a marginal decay of E-rate but a ma

51 utations promote tumour formation while also paradoxically causing cell lethality.

52 Paradoxically, CD26(high) T cells persist in and regress

53 Paradoxically, CENH3 is also adaptively evolving.

54 Paradoxically, centromeres are known both for their char

55 Age-dependent epigenetic divergence, paradoxically, changes to convergence in the later stage

56 HIV-1 disease progression is paradoxically characterized by systemic chronic immune a

57 Paradoxically, CLL cells in patients are highly activate

58 hus, a percept that is partially inferred is paradoxically considered more reliable than a percept ba

59 replicative capacity of subtypes A and C may paradoxically contribute to their more efficient spread

60 Paradoxically, control of this virus in rhesus macaques

61 Paradoxically, damage to specific parietal regions that

62 as removed by a single somatic mutation that paradoxically decreased binding to the foreign immunogen

63 ore, we also found that epicardial lidocaine paradoxically decreased left ventricular end-diastolic p

64 thermore, we found that epicardial lidocaine paradoxically decreased LV end-diastolic volume (preload

65 Paradoxically, despite the trauma experienced within thi

66 This may result in lower survival, perhaps paradoxically discouraging transplant centers from these

67 thway, but cells from Down syndrome patients paradoxically display reduced Hh signalling activity.

68 But surprisingly and paradoxically, DKO mice develop cardiac hypertrophy driv

69 (Arg(995)) contacts with beta3(Asp(723)) but paradoxically do not diminish the contribution of alphaI

70 Paradoxically, double mutants, but not TC0237(Q117E) sin

71 Paradoxically, during early tumor development in many ca

72 se strategies at the appropriate moments can paradoxically enable both population persistence and lon

73 f CD40 or Toll-like receptors (TLR), despite paradoxically enhanced plasma cell differentiation.

74 However, L1198F paradoxically enhances binding to crizotinib, negating t

75 f the substrate-binding pocket by bepristats paradoxically enhances catalytic activity of a and a' by

76 g is suboptimal for a perfect integrator, it paradoxically enhances performance in the presence of "l

77 by NMDA receptor blockade, a treatment that paradoxically enhances seizures in stg/stg mice.

78 sis showed that DHTS treatment of HeLa cells paradoxically enriched HuR binding to mRNAs with longer

79 Paradoxically, eosinophils also express an armory of gra

80 tome changes in drug-sensitive cancer cells, paradoxically establishing a tumour microenvironment tha

81 metabolic editing of luminal breast cancers, paradoxically establishing HT-driven self-renewal of dor

82 Paradoxically, even in infected, IFN-treated cells in wh

83 of Rac1 with Nf2 blocks tumor initiation but paradoxically exacerbates hepatomegaly induced by Nf2 lo

84 Paradoxically, excess heme is toxic to bacteria and path

85 Paradoxically, excitability in kisspeptin knock-out mice

86 rn neurons fire at a higher rate in vivo but paradoxically exhibit less spatial tuning than their mat

87 Paradoxically, existing studies based on aneuploid yeast

88 However, Hispanics paradoxically experience lower all-cause mortality rates

89 of parvalbumin-expressing interneurons that paradoxically express low levels of synaptic NMDA recept

90 As a result, paradoxically, fan-in triangles dominate the statistics

91 ad more centrosome-derived microtubules but, paradoxically, fewer steady-state microtubules.

92 key regulator of alpha4beta7 expression, was paradoxically found at higher levels in the plasma of SM

93 Paradoxically, free iron also has the potential to becom

94 nal responses in blood mononuclear cells but paradoxically further increases EPO.

95 Paradoxically, gain-of-function GLRA1 mutations also cau

96 and with known anti-inflammatory properties, paradoxically generates pro-inflammatory macrophages.

97 the entorhinal cortex in mouse brain slices paradoxically generates spiking of mature neurons in the

98 Paradoxically, GIP levels were also induced in these mic

99 nd suprachiasmatic nuclei (SCN) by light was paradoxically greatly reduced, while the downstream acti

100 Older patients with more limited disease paradoxically had better survival than would be expected

101 This success, perhaps paradoxically, has posed challenges for therapeutic deve

102 Paradoxically, here we demonstrate how HCV exploits the

103 Paradoxically, HFD further increases oxygen consumption

104 to a glucose challenge, higher height, and, paradoxically, higher BMI.

105 otor pathways had faster reaction times and, paradoxically, higher concentrations of GABA.

106 d to faster decisions, reduced accuracy and, paradoxically, higher confidence.

107 igher total size than if non-diffusing, and, paradoxically, higher size than in a corresponding homog

108 Paradoxically, homozygous genetic deficiency of PAI-1 is

109 Paradoxically, however, in mammals, it can also contribu

110 Paradoxically, however, increased virus replication dram

111 Paradoxically, however, MeCP2 protein levels were signif

112 Paradoxically, however, potent broadly neutralizing anti

113 Paradoxically, however, repeats are often strongly conse

114 Paradoxically, however, they turn out to be incorrect st

115 In the MRD, hurricanes have been paradoxically identified as both substantial agents of w

116 Paradoxically, IgGs are used to treat inflammatory disea

117 Paradoxically, IL-17A and IL-17-regulated proinflammator

118 Paradoxically, IL-32, a proinflammatory cytokine, was lo

119 Paradoxically, imaging studies have not detected DAT tar

120 ransmission and LTP, learning and memory are paradoxically impaired, providing a possible explanation

121 However, paradoxically, import of protein bacteriocins, the mecha

122 e (and thus economically irrational) choices paradoxically improve accuracy (and subsequent economic

123 Paradoxically, in a FeCl3 injury model, occlusion, but n

124 Thus, paradoxically, in amino acid-poor conditions the pro-ana

125 ted in a rise in [Ca(2+) ]m at baseline and, paradoxically, in an acceleration of Ca(2+) release.

126 -requires the transcription factor Rorgamma, paradoxically, in that Rorgamma is thought to antagonize

127 Paradoxically, in the NOD model, reduced thymic deletion

128 y, regulating for utilitarian algorithms may paradoxically increase casualties by postponing the adop

129 nesis can retard tumour growth, but may also paradoxically increase metastasis.

130 overexpression of miR-1 in the fly wing can paradoxically increase Notch activity independently of i

131 s greatly reduce retinol binding to RBP, yet paradoxically increase the affinity of RBP for its cell

132 nt can damage the intestinal microbiota and, paradoxically, increase susceptibility to infections.

133 inflammation (GM-CSF, TNFAIP2, IL-1beta) are paradoxically increased in TH1 cells expressing SUMOylat

134 ssed MYD88(L265P) B-cell growth in vitro but paradoxically increased in vivo accumulation of MYD88(L2

135 ule acidification upon ATP6ap2 knockdown but paradoxically increased proinsulin secretion.

136 BK inhibition also increased spike width but paradoxically increased the afterhyperpolarization.

137 nhibitory neurons in the cat's visual cortex paradoxically increased their firing rates and so could

138 ce) have markedly elevated HDL-C levels but, paradoxically, increased atherosclerosis.

139 activates and anchors ERK in the nucleus, it paradoxically increases and prolongs cytoplasmic ERK act

140 ontrast, pharmacological heart rate lowering paradoxically increases cardiovascular events in hyperte

141 ode of the voltage-dependent sodium current, paradoxically increases Rin and taum when activated.

142 ablation, while reducing seizure frequency, paradoxically increases seizure duration.

143 ugh the drug slows down cell growth, it also paradoxically increases the cell's concentration of ribo

144 ally rescues cells from SHMT inhibition, but paradoxically increases the inhibitor's cytotoxicity in

145 ism attenuates the risk of lung disease, yet paradoxically increases the risk of cardiovascular disea

146 Genetic deletion of the IL-33 receptor paradoxically increases TSLP production, which stimulate

147 Paradoxically, increases in the physical activity index

148 ion of Aspm reduces cerebellar growth, while paradoxically increasing the mitotic rate of CGNPs.

149 First-generation RAF inhibitors paradoxically induce ERK signaling in normal and tumor c

150 cancer, high-magnitude MEK/ERK activity can paradoxically induce growth inhibition.

151 e inhibiting protein synthesis, Shiga toxins paradoxically induce the expression of proinflammatory c

152 stimulate PDGFRbeta; instead, apoptosis was paradoxically induced.

153 asm for splicing function, dephosphorylation paradoxically induces similar movement, raising the ques

154 it required for channel function, EMRE could paradoxically inhibit uniporter complex formation if exp

155 Paradoxically, innate immune responses mediated by natur

156 anism by identifying that auto-inhibition is paradoxically instigated by incipient auto-phosphorylati

157 ncreasing popularity of TSPO PET imaging has paradoxically introduced substantial uncertainty regardi

158 cesses require specific enzymatic reactions, paradoxically involving short recognition sequences.

159 n immunodeficiency virus (HIV) infection but paradoxically is intensified by HIV-associated antiretro

160 ing endothelial adhesion and transmigration; paradoxically, it also promoted plaque instability by ca

161 (CBZ) has a known anti-epileptic mechanism, paradoxically, it has also been reported to increase epi

162 However, paradoxically, it preserves heart function after ischemi

163 lower-density pattern, as expected [4], but paradoxically, it reduces the apparent separation of dot

164 METHODS AND Paradoxically, Ldlr(-/-) (low-density lipoprotein recept

165 sms that limit vertical transmission but may paradoxically lead to virus-related pregnancy complicati

166 Despite its usefulness, this analogy has paradoxically led to neglecting real biogeographical pro

167 fic molecular pathway, these therapies have, paradoxically, led to a number of effects off their inte

168 the peak half-widths after suppression were paradoxically less than those without suppression; this

169 one marrow transplantation, had smaller but, paradoxically, less stable lesions with reduced macropha

170 These data indicate that CCL5 paradoxically limits macrophage accumulation in the inju

171 However, paradoxically loss of LKB1 in mouse embryonic fibroblast

172 Here, we show that, paradoxically, loss of both alleles of Rpl22 restricts l

173 Paradoxically, loss of Ccar2 in the mouse results in an

174 Paradoxically, loss of IRF8 in T cells has no effect on

175 from predators that prey on individuals, but paradoxically make schooling species energetically viabl

176 versities have not yet been able to satisfy--paradoxically, many are actually closing "niche" bioinfo

177 Paradoxically, MGMT-deficient GBM patients survive longe

178 Paradoxically, MoDC pulsed with H4B4*KLH, but not the ot

179 They were paradoxically more frequent for patients receiving compl

180 Paradoxically, most infants breastfed by HIV-positive wo

181 Paradoxically, mother and daughter centrioles overcome t

182 Paradoxically, mutagenic action of mismatch repair has b

183 Paradoxically, mutations of Trp-68 or Lys-170 markedly s

184 Paradoxically, necro-inflammatory diseases create the ne

185 Paradoxically, neither structural element performs its i

186 curs when TH levels are mildly reduced, but, paradoxically, not when they are severely reduced.

187 Paradoxically, NusA stimulates the function of the N and

188 At least one study paradoxically observed increased A(H3N2) infection among

189 antiretroviral therapy in HIV infection, and paradoxically occurs as HIV viremia is suppressed and CD

190 Paradoxically, only the ClfB(-) strain was significantly

191 Paradoxically, our closest living ancestors, nonhuman pr

192 Paradoxically, outcome information induced loss-causing

193 Paradoxically, patients who already had high preexisting

194 Paradoxically, PGC1beta represses the ubiquitin-proteoly

195 Paradoxically, plants overexpressing phyB also show earl

196 Paradoxically, pos-1 mutants exhibit striking defects in

197 Some anti-amyloid agents paradoxically prolong cytotoxicity by prolonging the lif

198 Paradoxically, prolonged deficiency of MEF2D in neonatal

199 ing pathways to drive transformation, it can paradoxically promote an irreversible cell cycle arrest

200 retory phenotype (SASP), senescent cells can paradoxically promote carcinogenesis.

201 suppresses deleterious inflammation, but may paradoxically promote fibrogenesis.

202 firing patterns; FSIs inhibit most SPNs but paradoxically promote the activity of a subset displayin

203 but not the soluble TNF receptor etanercept, paradoxically promoted the interaction between monocytes

204 , associated prostaglandin E2 (PGE2) release paradoxically promotes neighbouring CSC repopulation.

205 n mammals reactive oxygen species production paradoxically promotes virus pathogenicity by mechanisms

206 Paradoxically, protein levels of some Nrf2 antioxidant t

207 Paradoxically, proteins that promote closure of cytokine

208 rug previously linked with retinal toxicity, paradoxically provided potent neuroprotective effects.

209 Paradoxically, raising irradiance across the photopic ra

210 ponsive to further antiandrogen therapy, and paradoxically, rapid cycling between high and low serum

211 expression, yet inhibiting their recruitment paradoxically reactivates latent HIV-1 transcription.

212 Paradoxically, recent characterization of the proteome o

213 ay stimulation upstream of BRAF(V600E) could paradoxically reduce signaling downstream of BRAF(V600E)

214 A transcripts in circulating blood cells are paradoxically reduced in early stage, untreated and dopa

215 Paradoxically, reduced ER stress or Xbp1 splicing promot

216 Paradoxically, repeated switching between these same env

217 Paradoxically, reperfusion results in nitroxidative stre

218 ces inhibition of individual Rho GTPases may paradoxically result in pro-neoplastic effects.

219 tors that target proximal signaling pathways paradoxically results in hyporesponsive rather than hype

220 Paradoxically, RNA sequencing revealed a marked antagoni

221 at these inhibitory molecules, together with paradoxically robust, rapid, cell-autonomous IL-2 and IF

222 Paradoxically, S. aureus is a common inhabitant of the s

223 Paradoxically, SCML2 also prevents RNF2-dependent ubiqui

224 Paradoxically, senescence is also accompanied by increas

225 own cost management approaches that can both paradoxically shift effort from low-cost workers to much

226 Paradoxically, signals and factors involved in xenophagy

227 Paradoxically, signals known to promote T reg cell funct

228 Paradoxically, significant increased levels of TRF2 are

229 low-voltage fast electroencephalogram (EEG) paradoxically similar to that of wake, accompanied by ra

230 Paradoxically, simply increasing the "strength" of ERK1/

231 Paradoxically, some activated Treg cells express the afo

232 that therapy-induced cancer cell death can, paradoxically, stimulate and accelerate the growth of su

233 ration) and inhibitors (CaCl2 omission being paradoxically stimulatory).

234 Paradoxically, structural models for collision suggest t

235 Paradoxically, substoichiometric, ATM-independent, phosp

236 Paradoxically, such local compressive buckling should no

237 ta reveal how a widely consumed nutrient can paradoxically sustain brain starvation signals, and iden

238 Paradoxically, sustained inflammation in sepsis may lead

239 Paradoxically, TAF carried no mutations in MED12, sugges

240 old higher in cells with reduced Cdc48, yet, paradoxically, telomeres are shorter.

241 Paradoxically, TGF-beta hyperactivity has been postulate

242 n of the GYxxO trafficking motif and reveal, paradoxically, that viral control is enhanced in a macaq

243 nduced pluripotent stem cells, we show that, paradoxically, the cardiogenic fate of CNC(kit) is regul

244 lly or by treating the cells with Gefitinib, paradoxically, the cells demonstrated increased cell mig

245 Paradoxically, the DKO mice were able to survive gradual

246 Paradoxically, the effects of genotypic context in indiv

247 Paradoxically, the evolution of rhizomyines was accelera

248 Paradoxically, the interface is also required for select

249 Paradoxically, the introduction into Min L of one mutati

250 Paradoxically, the MMR-nicking complex Pms2/Mlh1 is appa

251 Paradoxically, the nonselective CB1/CB2 receptor agonist

252 Paradoxically, the pneumococcal capsule sensitizes the b

253 lting in regioselective C-H bond activation; paradoxically, the strongest C-H bond reacts preferentia

254 Paradoxically, the thymidine kinase (TK) encoded by Kapo

255 Paradoxically, the tumor harbored an activating MAPK1 E3

256 Paradoxically, there are currently no approved therapies

257 Paradoxically, there is a vast excess of Mcm2-7 relative

258 Here we show that, paradoxically, these artefacts can be eliminated by deli

259 self-photographs ("selfies"), we show that, paradoxically, these challenges can be exacerbated by te

260 Paradoxically, these highly variable receptive fields go

261 Paradoxically, these results suggest that biodiverse sys

262 Paradoxically, these sequences are also replete with coi

263 Paradoxically, this also markedly attenuates IDOL-mediat

264 mined associated with active ribosomes, but, paradoxically, this correlated with a global reduction i

265 ouble-strand breaks in eukaryotic cells, but paradoxically, this gene cluster is found in the probiot

266 Paradoxically, this inhibition renders stem cells hypers

267 nce of intracellular pathogens in bat hosts; paradoxically, this may leave them more susceptible to i

268 Paradoxically, this resulting processive motion relies o

269 Paradoxically, this sustained MEK1/2 and ERK1/2 activati

270 Paradoxically, this treatment led to feedback-mediated s

271 Paradoxically, those patients with the most severe coron

272 deletion of autophagy in myeloid cells leads paradoxically to better control of viral infection in vi

273 ates nucleotide exchange on RabE(RAB11) and, paradoxically, to a lesser yet substantial extent, on Ra

274 , including DNA replication and repair, and, paradoxically, transcription.

275 Paradoxically, tumors overexpressing CAIX showed lower e

276 on induces chromosome segregation errors and paradoxically undermines genomic integrity.

277 but in some patients with epsilon3/epsilon4, paradoxically up-regulated the M1 type.

278 ription factors, normally tumor-suppressing, paradoxically upregulate c-Myc epigenetically in concert

279 ll survival of patients with stage I disease paradoxically was significantly better (P < 0.001).

280 been suggested to underlie this inhibition, paradoxically we found that gamma-2, and thus AMPAR gati

281 Paradoxically, we also found that the substrate receptor

282 Paradoxically, we find that Gal1p, an enzyme needed for

283 Paradoxically, we found that Rb knockdown prior to infec

284 Paradoxically, we observed an overall increase in intrac

285 Paradoxically, we observed that subjects with cat allerg

286 Paradoxically, we observed that the incorporation of GLA

287 Hsp70 is stress-inducible, but paradoxically, we report here that JB12 was degraded by

288 Paradoxically, we use broadband-absorbing organic semico

289 , spatially targeted antennal scanning that, paradoxically, weakened individual neural responses.

290 indicating that the most preventable strokes paradoxically were more likely to receive acute treatmen

291 s that the proportion of single units firing paradoxically when filling pressure increases is augment

292 that M. oryzae virulence is enhanced, quite paradoxically, when a public good mutant is present in a

293 Paradoxically, while loss of BRCA2 promotes tumor format

294 Paradoxically, while NPR1 is essential for defense gene

295 Paradoxically, while typical ILD-sensitive neurons of th

296 Paradoxically, with ageing and falls, initiation slowing

297 chondrial abnormalities, but was associated, paradoxically, with increases in PIP3 concentrations.

298 th larger size for age 1 and older fish but, paradoxically, with smaller size of age 0 fish.

299 ing fat accumulation are enhanced in HI but, paradoxically, without any significant effect on liver f

300 as to the mechanisms by which opioids might paradoxically worsen pain, and implementation of an opio