コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 able databases) and 49% are gene duplicates (paralogues).
2 protein gene RPL22A, but not its unenriched paralogue.
3 ponds with a key, conserved eukaryotic Rad51 paralogue.
4 nBank and the large number of highly similar paralogues.
5 s, but in S. maritima is encoded by over 100 paralogues.
6 Most teleost fish possess two MSTN paralogues.
7 tic conservation with respect to their human paralogues.
8 n function between the closely related SEC23 paralogues.
9 ects in OXS2 and three of the four OXS2-like paralogues.
10 ncluding RAD51-related proteins termed Rad51 paralogues.
11 on of these non-redundant, tandemly arranged paralogues.
12 rk of vertebrate calpains, including teleost paralogues.
13 PA1 gene but Arabidopsis possesses five RPA1 paralogues.
14 RIM5alpha orthologues and in closely related paralogues.
15 gene duplication and creation of families of paralogues.
16 tional diversity among the 3 Arabidopsis CRT paralogues.
17 ing members of the miR-17-92 cluster and its paralogues.
18 al divergence relative to their SLO1 channel paralogues.
19 B. napus with the participation of ABI1-like paralogues.
20 nce and functional divergence of the BnaABI1 paralogues.
25 S domain-containing protein ENL, but not its paralogue AF9, is required for disease maintenance in ac
26 rst reported comprehensive analysis of Hsp90 paralogue affinity and selectivity in the clinical Hsp90
27 degree of similarity between the S. gordonii paralogues, analysis of SecA-SecA2 chimeras indicates th
28 s that specifically antagonize each receptor paralogue and yet cross-react with the human and mouse s
29 d the zebrafish genome to identify potential paralogues and confirmed their homology, bringing the to
30 n IPTL, as shown by the accumulation of LC3B paralogues and diminishment of lysosome associated membr
32 s, which are the most diverged region of the paralogues and probably evolved independently after a ge
33 monstrate correlation between Notch and Mef2 paralogues and support the notion that Notch-MEF2 synerg
35 SM/type III-A and CMR/type III-B), five Cas6 paralogues and two different CRISPR-repeat families (AB
38 residues in evolutionarily related proteins (paralogues) and, where appropriate, transfers annotation
39 agonists that selectively target each Jagged paralogue, and determine a crystal structure that explai
41 ed sequence heterogeneity in mammalian Notch paralogues, and should allow the development of paralogu
42 lt of the expression of multiple Kir2 family paralogues, and the inwardly rectifying conductance cont
44 r because of the observation that various PC paralogues are activated at different organellar pH valu
46 at is found in budding yeast where the RAD51 paralogues are fully dependent on the SRS2 anti-recombin
51 an contains approximately the same number of paralogues as found in the two soybean homeologues combi
53 itration calorimetry studies show that these paralogues bind the product of the methylation reaction,
54 only the major binding modes that relay pan-paralogue binding or, conversely, paralogue selectivity,
55 cking the endogenous bak1 and its functional paralogue, bkk1, produced plants that were viable but ex
56 ession pattern of two evolutionarily distant paralogues, BnaA01.ABI1.a and BnaC07.ABI1.b in B. napus
57 were not compensated by the closely related paralogue Bright-derived protein (Bdp)/Arid3b, suffered
58 ling tight co-expression between the IGF-IRa paralogues, but expression divergence comparing IGF-IRa
59 ared the physical binding properties of each paralogue by surface plasmon resonance and determined th
63 ome duplication, which suggests that ancient paralogues can remain in the same regulatory networks fo
65 is a key effector in abscission, whereas its paralogue, CHMP4C, is a component in the abscission chec
66 that in zebrafish two subfunctionalized cmas paralogues co-exist, we introduce a novel and unique mod
67 that HELQ interacts directly with the RAD51 paralogue complex BCDX2 and functions in parallel to the
68 us proteins, evolved from a more ancient two-paralogue complex because of a gene duplication that was
73 and HrpS functionalities suggest how partial paralogue degeneration has potentially led to a novel co
75 Here we show in mice that different NAIP paralogues determine the specificity of the NLRC4 inflam
78 acking Dcx and/or its structurally conserved paralogue, doublecortin-like kinase 1 (Dclk1), show impa
79 ABI1 gene orthologue and Brassica napus gene paralogues encoding protein phosphatase 2C (PP2C, group
85 indicated that expression of two fibronectin paralogues, fn1 and fn1b, are induced by injury in epica
90 ally completely conserved in orthologues and paralogues from invertebrates to humans, and clinical fo
93 Individual AdoMetDC-SpdSyn fusion protein paralogues from Tetrahymena exhibit undetectable AdoMetD
94 proteins in Paramecium cells, we found that paralogues from the two most recent whole-genome duplica
96 and I304N mutant FMRP isoforms and the FMRP paralogues FXR1P and FXR2P (also known as FXR1 and FXR2)
97 et al. investigate the role of Gata6 and its paralogue Gata4 in mouse embryonic pancreas and show tha
99 ry microRNAs and temporal divergence of gene paralogues generated in the teleost genome duplication.
106 ic clones showed that the effects that these paralogues have on proliferation serve to promote cell c
107 ound that it includes a cohesive outgroup of paralogues (herein coined LoaP), which are often positio
108 Using zebrafish, we found that the HNF1beta paralogues hnf1ba and hnf1bb, which encode homeodomain t
109 expression assays reveal that Hoxb4 and its paralogue Hoxd4 are necessary and sufficient for cell se
111 uctures of tau55-HPD and its closely related paralogue Huf and used in silico docking methods to iden
114 function of gp96 (HSP90b1, grp94), an HSP90 paralogue in the endoplasmic reticulum (ER), is believed
118 or understanding the role of the human RAD51 paralogues in Fanconi anaemia and cancer predisposition.
119 The exclusive presence of highly conserved paralogues in higher organisms led us to assess whether
121 ous to heteromeric complex formation by BRE1 paralogues in other organisms, yBre1 forms a homo-multim
123 nt a comprehensive analysis of MtrA and MtrC paralogues in S. oneidensis to define the roles of these
124 demonstrate an unexpected role of the Rad51 paralogues in stabilizing the Rad51 filament against a b
125 ay in dicots may have functionally redundant paralogues in switchgrass and therefore require further
126 trand invasion, however, the function of the paralogues in the process of homologous recombination is
127 that the differential use of duplicated MRF paralogues in this novel two-component myogenic system f
128 tentially broad role for RNase G, an RNase E paralogue, in the trimming of 5'-monophosphorylated ends
132 dies suggest that silencing of either clag 3 paralogue is associated with the enrichment of specific
133 sociated ClpX must recruit ClpP, for which a paralogue is not duplicated within any of the nitrogen f
135 esults show that the presence of these three paralogues is associated with different activities, both
139 vated protein kinase Slt2p, its pseudokinase paralogue, Kdx1p, and an associating transcription facto
140 lso report that a high dose of either of two paralogue kinases, Kin1 and Kin2, overcomes the defectiv
141 esults in an increased reliance on the FabHb paralogue leading to a greater proportion of straight ch
142 ucing a single historical mutation from each paralogue lineage into the resurrected ancestral protein
144 eine-rich transcriptional regulator, and its paralogues (LMO2, LMO3 and LMO4) have each been previous
146 d the possibility that additional JAM family paralogues may also function in muscle development.
149 circle accumulation, suggesting that the two paralogues mediate overlapping and nonredundant function
150 on assays show that CheR2, but not the other paralogues, methylates the McpS and McpT chemotaxis rece
152 nnotation errors, nomenclature variation and paralogues; moreover, GenBank's structure and tools are
155 transcription factor FOUR LIPS (FLP) and its paralogue MYB88 regulate terminal divisions during stoma
161 TBC1D1), a Rab GTPase-activating protein and paralogue of Akt substrate of 160 kDa (AS160), has been
163 Gene expression studies identified MtLAX2, a paralogue of Arabidopsis (Arabidopsis thaliana) AUX1, as
165 protease 50 (TSP50) and the testis-specific paralogue of CCCTC-binding factor, BORIS (brother of the
166 to suggest that a nitrogen fixation-specific paralogue of ClpX is used to control the accumulation of
168 efect, is to modulate utrophin, a functional paralogue of dystrophin, able to compensate for the prim
169 nants of PC activation, we analyzed PC1/3, a paralogue of furin that is activated at a pH of approxim
170 However, POLRMT also interacts with the paralogue of h-mtTFB2, h-mtTFB1, which is a 12S ribosoma
176 nt evidence indicating that SlrA, which is a paralogue of SinI, is like SinI, an antirepressor that b
177 protein (TBP)-associated factor 7l (Taf7l; a paralogue of Taf7) and TBP-related factor 2 (Trf2) are c
179 ong the regulated genes was Rv0190/MT0200, a paralogue of the copper metalloregulatory repressor CsoR
184 The SAS6-like (SAS6L) protein, a truncated paralogue of the ubiquitous basal body/centriole protein
185 hiamin pyrimidine synthase (thiC) revealed a paralogue of thiC (bzaF) clustered with anaerobic vitami
187 4(yeast)/Pelota(mammals) and Hbs1, which are paralogues of eRF1 and eRF3, are implicated in these pro
188 iRNA precursors, and previously unrecognized paralogues of functionally important miRNA families (e.g
190 share 4 unique microRNA families, 15 unique paralogues of more primitive microRNA families, and 22 u
193 oteins of streptococci and staphylococci are paralogues of SecA and are presumed to have an analogous
194 l other adaptin complex subunits, as well as paralogues of the syntaxins and Rabs specific for the ot
198 coactivator CREB binding protein (CBP), its paralogue p300, and the retinoblastoma protein (pRb; als
200 roteins interact directly with ATML1 and its paralogue PDF2 and that silencing of both HD-ZIP transcr
201 lino oligonucleotides we show that both Tbx6 paralogues perform essential functions in the developmen
202 B forms homodimers and heterodimers with its paralogue PHOX2A in vitro, we tested the hypothesis that
204 istoyl sequence in SCCRO3, one of four SCCRO paralogues present in humans that localizes to the membr
207 product of RAD51B interacts with that of its paralogue RAD51, which is associated with congenital mir
210 e methods of copy number typing based on the paralogue ratio test (PRT) to assess beta-defensin copy
212 urpose of this study was to evaluate whether paralogue ratio tests (PRT) using real-time PCR can accu
216 RNA-binding motif protein 15 (RBM15) and its paralogue RBM15B, which bind the m(6)A-methylation compl
218 ge of protists, demonstrating that the Rad51 paralogue repertoire in T. brucei is unusually large amo
219 g mutants in both ecotypes lacking the DELLA paralogues REPRESSOR OF ga1-3 (RGA) and GA INSENSITIVE (
222 erized the interaction between NUPR1 and the paralogue RING1B in vitro, in silico, and in cellulo.
224 hough the function of RNF114 is unknown, its paralogue RNF125 has been shown to regulate the RIG-I/MD
225 ffects are specific to rhomboid, because its paralogue roughoid is neither required nor sufficient fo
226 thin the genome in a strain lacking the Rpl8 paralogue RPL8A, demonstrating that the gene targeted fo
229 analysis that allows for rationalization of paralogue selectivity and defines not only the major bin
230 relay pan-paralogue binding or, conversely, paralogue selectivity, but also identifies molecular cha
232 tion patterns, and that less closely related paralogues showed evidence of both conservation and dive
233 Identical experiments with purified SUMO paralogues showed that SUMO-1 was well digested by our p
234 lear positioning in guard cells, whereas its paralogue SINE2 contributes to innate immunity against a
237 udied the poorly characterized SNX20 and its paralogue SNX21, which contain an N-terminal PX domain a
239 3% identical in amino acid sequence but have paralogue-specific effects on cell proliferation, metast
242 and the L. monocytogenes genome contains two paralogues, spxA1 and spxA2 Here, we demonstrate that sp
244 The nucleoid-associated protein H-NS and its paralogue StpA are global regulators of gene expression
245 erminal region (RQC) found in the other RecQ paralogues; such a region consists of a zinc domain and
247 other protists possess highly divergent XPB paralogues suggesting that XPBs specialized in transcrip
248 together with studies on Fur homologues and paralogues, suggests that in fact the Zn2 site is the re
249 Structure-guided mutagenesis of the close paralogue SWEET1 from Arabidopsis identified key residue
252 -43, we knocked out zebrafish Tardbp and its paralogue Tardbp (TAR DNA binding protein-like), which l
254 f the xenophagy cargo receptor Ndp52 and its paralogue Tax1bp1, which we demonstrate here to be a bon
255 e show that downregulation of TCF7L1 and its paralogue TCF7L2 reduces tumor growth in a xenograft mod
256 CUL3(KBTBD8) monoubiquitylates NOLC1 and its paralogue TCOF1, the mutation of which underlies the neu
258 that a knockout of the gene for the smaller paralogue, termed XPB-R (R for repair) resulted in viabl
262 2 and RING 1A, which are partially redundant paralogues that together account for the E3 ubiquitin li
263 istent with the Shu complex containing Rad51 paralogues, the methyl methanesulphonate sensitivity of
264 mited use for environmental barcoding due to paralogues, the potential for unidentifiable chimaeras a
265 that Csm2 interacts with Rad51 and the Rad51 paralogues, the Rad55-Rad57 heterodimer and that the Shu
266 show that the Saccharomyces cerevisiae Rad51 paralogues, the Rad55-Rad57 heterodimer, counteract the
267 cellular roles for these P. aeruginosa SPase paralogues; the role of PA1303 is integrated with the qu
268 ate cell-specific expression of the teashirt paralogue tiptop, which is not normally expressed in lar
269 intercalating between principal cells, and a paralogue, tiptop, is expressed in forming tubules.
271 olic enzyme non-quiescent mutant 1 (NQM1), a paralogue to the pentose phosphate pathway enzyme transa
273 ignaling pathways recruit distinct myosin II paralogues to generate the contractile apparatus at apic
274 rsing out the contribution of the four Hsp90 paralogues to the perceived biological activity with the
277 The regional expression of the Y-linked paralogue Uty (ubiquitously transcribed tetratricopeptid
278 We identified wake-up-call (wuc), a lin-52 paralogue, via a physical interaction with the tMAC lin-
279 ma-carboxylation in osteoblasts, whereas its paralogue, VKORC1L1, is dispensable for this function an
281 -2/simian immunodeficiency virus (SIV) SIVsm paralogue Vpx, hijack the CRL4(DCAF1) E3 ubiquitin ligas
284 The functional divergence between kindlin paralogues was assessed using the sequence swap (chimera
285 s transcriptional divergence between the two paralogues was associated with high levels of histone H3
286 hat led to the functional diversification of paralogues, we tracked duplicate retention patterns, exp
288 omains are extremely similar, WelLFY and its paralogue WelNDLY exhibit distinct DNA-binding specifici
289 the miR-17 approximately 92 cluster and its paralogues were also highly expressed in ALK(+) ALCL and
292 inding to histone tails of the human class A paralogue, which has a histidine at this position, is se
293 or the potential function of the human RAD51 paralogues, which are known to be involved in cancer pre
295 Several ribosomal protein families contain paralogues whose roles may be equivalent or specialized
297 s, however, possess two highly divergent XPB paralogues with only the larger being identified as a TF
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。