ライフサイエンスコーパス: paraquat

1 rent oxidizing agents (hydrogen peroxide and paraquat).

2 ic insult (i.e., injections of the herbicide paraquat).

3 iotics such as berberine, rhodamine 123, and paraquat.

4 cold and reactive oxygen species-generating paraquat.

5 )O(2) production by the redox cycling agent, paraquat.

6 e susceptible to oxidative stress induced by paraquat.

7 ced tolerance to oxidative stress induced by paraquat.

8 sed resistance to the free-radical generator paraquat.

9 ion has been reported between a cryptand and paraquat.

10 e and Delta sodA1 cells after treatment with paraquat.

11 etected at lower levels after treatment with paraquat.

12 in brain regions of normal mice treated with paraquat.

13 ction exhibit variation in susceptibility to paraquat.

14 factors, we treated DJ-1-deficient mice with paraquat.

15 eroxide generated by the redox-cycling agent paraquat.

16 ent with the superoxide-generating compound, paraquat.

17 ecrotic lesions, and increased resistance to paraquat.

18 of nickel, copper, alkaline pH, menadione or paraquat.

19 he knockdown of TcSOD2 by exposing larvae to paraquat.

20 in; however, the mutant was less tolerant to paraquat.

21 der aerobic conditions or in the presence of paraquat.

22 roxides, and the superoxide-generating agent paraquat.

23 Y) were protected from damage to cadmium and paraquat.

24 /- and Prdx6+/+ mice and those injected with paraquat.

25 onse to nitrite and 37 genes specifically to paraquat.

26 was studied in mice exposed to the herbicide paraquat.

27 ath following exposure to subtoxic levels of paraquat.

28 but not by tert-butylhydroquinone (tBHQ) or paraquat.

29 enhanced by the superoxide-producing agent, paraquat.

30 of c-FLIP(L) protein induced by menadione or paraquat.

31 HeLa cancer cells treated with menadione or paraquat.

32 ts and mitochondria following treatment with paraquat.

33 the superoxide-generating redox-cycling drug paraquat.

34 one of the most powerful hosts reported for paraquats.

35 tri(1,4,7,10,13-pentaoxatridecyl) (3b), with paraquat (1) have 2:1 stoichiometry.

36 3a forms a strong 1:1 complex with paraquat (1) in acetone solution with a high apparent as

37 Paraquat (10-100 microm) was found to cause a 2-4-fold i

38 f a tetracationic molecular square, cyclobis(paraquat-4,4'-biphenylene), as the pi-electron deficient

39 ger, square-shaped diradical host, [cyclobis(paraquat-4,4'-biphenylene)](2(+*)) (MS(2(+*))).

40 ant K(a) = 5.0 x 10(6) M(-1) in acetone with paraquat, 9000 times greater than the crown ether system

41 epletion in the presence of methyl viologen (paraquat), a known agent of oxidative stress and source

42 to dopamine cells, suspicion has focused on paraquat, a common herbicide with chemical structure sim

43 atenin signaling manipulation in vitro using paraquat, a known oxidative stress inducer.

44 S1 gene render sos1 mutants more tolerant to paraquat, a non-selective herbicide causing oxidative st

45 Paraquat, a prooxidant widely used in stress tests, had

46 Paraquat, a reactive oxygen species generator, alone was

47 a producer of reactive oxygen species (ROS), paraquat, all rescued wild-type worms from hemiasterlin

48 higher risk when exposed to either maneb or paraquat alone (odds ratio = 2.27, 95% CI: 0.91, 5.70) o

49 the most severe consequences of exposure to paraquat, an herbicide that causes rapid alveolar inflam

50 Exposure to paraquat, an herbicide with structure similar to the dop

51 ed by low levels of the superoxide-generator paraquat and by a mutation that inhibits respiration.

52 utant are killed to a greater extent only by paraquat and diamide, whereas they are less susceptible

53 etermination of two bipyridylium herbicides, paraquat and diquat, in cowpeas by UPLC-MS/MS in a total

54 dietary supplementation with two compounds, paraquat and ethanol, on food ingestion and preference.

55 hypersensitivity of SelH shRNA HeLa cells to paraquat and H2O2, but not to hydroxyurea, neocarzinosta

56 tenuated neuronal death mediated by combined paraquat and iron treatment.

57 opathology, were treated with the pesticides paraquat and maneb (either singly or together), and thei

58 ergic neurotoxicity produced by the combined paraquat and maneb model of the Parkinson disease phenot

59 Environmental paraquat and neonatal iron exposure have both been separ

60 HL knockout animals with the potent oxidizer paraquat and observed a robust induction of cellular sen

61 ity to those environmental agents, including paraquat and rotenone, linked to PD in humans.

62 nsitivity to the superoxide-generating agent paraquat and to organic hydroperoxides.

63 nd 4, possessed diminished binding with both paraquats and diquat relative to the 30-crown-based anal

64 pyocyanin (and the closely related molecule paraquat) and the acyl-homoserine lactone 3-OC12-HSL sig

65 as hypersensitive to the redox-cycling agent paraquat, and a plasmid expressing YggX complemented the

66 ed by their respective inducers: salicylate, paraquat, and decanoate.

67 to killing by hydrogen peroxide, menadione, paraquat, and diamide.

68 stimuli such as staurosporine, thapsigargin, paraquat, and H(2)O(2) showed significantly enhanced sur

69 rodegeneration, including hyperoxia, dietary paraquat, and heat stress.

70 ve stresses induced by hydrogen peroxide and paraquat, and it reduced transformation efficiency about

71 P1 to P28 and was also sensitive to hypoxia, paraquat, and myocardial infarction.

72 Environmental toxins, such as the herbicide paraquat, appear to be risk factors, and it has been pro

73 sponse to oxidative stress (i.e. H(2)O(2) or paraquat application), heat shock, or wounding.

74 , Zat7, or WRKY25 in response to H(2)O(2) or paraquat application.

75 l tested compounds, not even of the cationic paraquat at pH 7, 9, and 11.

76 or that can situate alongside a pi-accepting paraquat-based macrocycle by folding of a flexible linke

77 be an aromatic edge-to-face interaction of a paraquat beta-proton with the hydroquinone moiety; this

78 The complex based on dibenzo-24-crown-8 and paraquat bis(hexafluorophosphate) is not ion paired in s

79 e; the value of the dissociation constant of paraquat bis(hexafluorophosphate) was determined to be 4

80 However, exposure to 38 degrees C, paraquat, cadmium, or deletion of SOD1 enhanced two- to

81 We find that paraquat can replicate a broad spectrum of parkinsonian

82 Ingestion of paraquat causes multi-organ failure.

83 nds the KPF6 and allows the colored cryptand-paraquat complex to reform.

84 red in the presence of paraquat, there was a paraquat concentration-dependent increase in the formati

85 best estimated through measurement of blood paraquat concentrations but this facility is not availab

86 0 nm was linearly proportional to thiram and paraquat concentrations in the ranges from 0.5 to 1000 m

87 We also find that exposure of adults to paraquat converts cytosolic aconitase to IRP1 but has no

88 2 expression is also induced by glutathione, paraquat, copper, and naphthalene acetic acid (NAA) via

89 Formation of the paraquat/cryptand-based pseudorotaxanes can be switched

90 ement of ROS from NADPH oxidase in mediating paraquat cytotoxicity in BV-2 microglial cells and this

91 Isotopically labeled internal standards, Paraquat-D6 and Diquat-D4, were used and added to the te

92 We found four independent factors for paraquat death prediction: amylase, PaCO2, leukocyte num

93 new cryptands form pseudorotaxanes with the paraquat derivative N,N'-bis(beta-hydroxyethyl)-4,4'-bip

94 atives and bis(p-phenylene)-34-crown-10 with paraquat derivatives are all ion paired in solution and

95 It was found that these cryptands bind paraquat derivatives very strongly.

96 The first cylindrical host for paraquat derivatives was prepared and characterized by X

97 Their complexes with paraquat derivatives were studied by proton NMR spectros

98 s a luminescent crown ether based host 1 and paraquat derivatives, 2(PF(6))(2) and 3(PF(6))(2), as gu

99 MOF-1001 is capable of docking paraquat dication (PQT2+) guests within the macrocycles

100 e included as controls (simazine, maneb, and paraquat dichloride).

101 The same dose of paraquat did not interfere with implantation in WT mice.

102 K+ displaces paraquat diol from the cryptands, converting yellow-oran

103 been synthesized and their interaction with paraquat diol has been investigated.

104 4,4'-bipyridinium bis(hexafluorophosphate) ("paraquat diol", 6): Ka=1.0x10(4) and 1.4x10(4) M-1, resp

105 ctures are reported for both cryptands, both paraquat diol-based pseudorotaxanes, both NH4PF6 complex

106 aminergic neuron death, and morbidity during paraquat exposure but confer sensitivity to hydrogen per

107 test the hypothesis that chronic, low-level paraquat exposure causes restrictive lung function with

108 es not readily support the causative role of paraquat exposure in idiopathic Parkinson's disease.

109 ence interval = 0.9-3.0) with the cumulative paraquat exposure index in models adjusted for age, weig

110 In linear regression models, cumulative paraquat exposure was not an independent predictor of VA

111 The association of paraquat exposure with ventilatory equivalent and oxygen

112 gnificantly higher with increased cumulative paraquat exposure.

113 They generated estimates for maneb and paraquat exposures incurred between 1974 and 1999.

114 on mitochondrial aconitase, indicating that paraquat generates superoxide in the cytosol but not in

115 ding to the beta-pyridinium hydrogens of the paraquat guests.

116 Most (66.6%) were paraquat handlers; 24.8% of handlers and 27.3% of nonhan

117 Its complex with paraquat has 1:2 stoichiometry.

118 Exposure of mice to the herbicide paraquat has been demonstrated to result in the selectiv

119 exposure to the oxidant-producing herbicide paraquat has been implicated as a risk factor in Parkins

120 such as neurotoxicity induced by rotenone or paraquat--have emphasised that environmental agents may

121 fection, or treatment with salicylate or the paraquat herbicide that generates activated oxygen speci

122 ohistochemistry, and compared the effects of paraquat, hydrogen peroxide, and t-butyl hydroperoxide o

123 Nrf2 activity, increases their resistance to paraquat, hydrogen peroxide, cadmium, and UV light, rend

124 s study assessed the brain uptake of [(11)C]-paraquat in adult male rhesus macaques using quantitativ

125 poptotic gene BAX, and superoxide-generating paraquat in Arabidopsis or Nicotiana benthamiana.

126 Results showed minimal uptake of [(11)C]-paraquat in the macaque brain.

127 be for the sensitive detection of thiram and paraquat in water and food samples.

128 models of Parkinson's disease (PD), MPTP and paraquat, in young animals, its prolonged elevation resu

129 that exposure to a combination of maneb and paraquat increases PD risk, particularly in younger subj

130 Examples include enhanced methyl viologen (Paraquat)-induced oxidative stress tolerance in Mn-super

131 The protocol was set up using Paraquat-induced carbonylation, a model that induces pro

132 ROS and the underlying signaling pathway for paraquat-induced cytotoxicity to BV-2 microglial cells.

133 (EUK-134 and EUK-189) in protecting against paraquat-induced dopaminergic cell death in both the rat

134 thway inhibitor CEP-11004 effectively blocks paraquat-induced dopaminergic neuronal death in vivo.

135 rray analyses were conducted to evaluate the paraquat-induced global transcriptional response of Baci

136 pherol and N-acetylcysteine (NAC) attenuated paraquat-induced implantation failure in P(4)-treated Fk

137 from this enzyme are likely to contribute to paraquat-induced lung toxicity.

138 In the paraquat-induced model of Parkinsonism, this nigro-vagal

139 dings support a role for oxidative stress in paraquat-induced neurotoxicity and suggest novel therape

140 EUK-134 or EUK-189 significantly attenuates paraquat-induced neurotoxicity in vitro in a concentrati

141 amine synthesis, can alter susceptibility to paraquat-induced oxidative damage.

142 uced uterine PRDX6 levels are susceptible to paraquat-induced oxidative stress (OS), leading to impla

143 2-treated UOK262 renal carcinoma cells and a paraquat-induced oxidative stress cell model, demonstrat

144 FOXO transcription factor and protected from paraquat-induced oxidative stress.

145 a53Thr mutant form of the protein, displayed paraquat-induced protein aggregates but were completely

146 Paraquat-induced ROS production (including superoxide an

147 d kinases (ERK1/2) could partially attenuate paraquat-induced ROS production and cell death.

148 Paraquat-induced ROS production was inhibited by NADPH o

149 f superoxide dismutase (SOD) enzymes against paraquat-induced toxicity, as well as the therapeutic po

150 Apocynin and DPI also rescued cells from paraquat-induced toxicity.

151 selective PKCdelta inhibitor, also inhibited paraquat-induced translocation of p67phox.

152 Our data show that paraquat induces the sequential phosphorylation of c-Jun

153 Although intraperitoneal paraquat injections in mice cause a selective loss of do

154 s is sufficient to confer protection against paraquat insult.

155 gly, protection against the neurotoxicity of paraquat is conferred by mutations that elevate dopamine

156 in vivo effects have been ambiguous because paraquat is di-cationic in plasma, which raises question

157 This acute exposure study found that paraquat is excluded from the brain by the blood brain b

158 duced by treatment with rotenone, MPP(+), or paraquat is independent of complex I inhibition.

159 Paraquat is known to induce toxicity in cells by stimula

160 Paraquat is thus frequently used in the fruit fly Drosop

161 -1)) and very high association constants for paraquats (Ka > 10(5) M(-1)) in acetone at 22 degrees C.

162 rotenone or induction of oxidative stress by paraquat led to an increase in the phosphorylation of v-

163 Non-transgenic mice chronically exposed to paraquat + maneb exhibited significant reductions in loc

164 Even a single injection of paraquat + maneb in the non-transgenic treated group mod

165 To begin to determine critical pathways of paraquat + maneb neurotoxicity, the functions of cell de

166 d to saline, paraquat, or the combination of paraquat + maneb twice a week for 9 weeks.

167 assertion that protective mechanisms against paraquat + maneb-induced neurodegeneration could involve

168 droperoxides in the midbrain and striatum of paraquat + maneb-treated non-transgenic mice was not det

169 l toxins, including environmental pesticides paraquat, maneb, and rotenone.

170 sociated with the disorder and that iron and paraquat may act via common oxidative stress-mediated me

171 valent and oxygen desaturation suggests that paraquat may be associated with subclinical gas exchange

172 gnaling cascade is a direct activator of the paraquat-mediated nigral dopaminergic neuronal apoptotic

173 antimycin A prevented mitochondrial- but not paraquat-mediated oxygen flux into cells.

174 systemic administration of EUK-189 decreases paraquat-mediated SNpc dopaminergic neuronal cell death

175 the CL mutants do not display sensitivity to paraquat, menadione or hydrogen peroxide (H2O2).

176 hibit excessive elevations of ROS induced by paraquat, menadione, and light stress and prevent cell d

177 ance was observed for fibroblasts exposed to paraquat, methyl methanesulfonate, and rotenone (P<0.05

178 Although in vitro evidence for paraquat neurotoxicity to dopamine cells is well establi

179 Paraquat neurotoxicity was compared in control animals v

180 ing microsensors, we measured the effects of paraquat on oxygen flux into murine lung epithelial cell

181 and wild-type (Prdx6+/+) macrophages, and of paraquat on Prdx6-/- and Prdx6+/+ mice.

182 Rats were given injections of paraquat once weekly for 3 weeks to induce features of P

183 osure to reactive oxygen species generators (paraquat or cadmium), or lack of superoxide dismutases.

184 stance of MCF7 breast cancer cells to either paraquat or doxorubicin.

185 ative stress induced by agents such as H2O2, paraquat or oxygen.

186 und its axis and lies with its smaller side (paraquat or phenyl ring) parallel to the surface to acco

187 eir tolerance to oxidative stress imposed by paraquat or t-butyl hydroperoxide, or were subjected to

188 of fast-exchange host-guest systems based on paraquats or viologens (G(2+)2X(-)) and crown ethers (H)

189 = 2.2 (95% CI: 1.5, 3.3), and the herbicide paraquat (OR(adj) = 1.8 (95% CI: 1.1, 2.8) was significa

190 y (i.e. treatment of mice with the herbicide paraquat) or transgenic protein overexpression, the intr

191 ound that exposure of RPE cells to H(2)O(2), paraquat, or A2E-mediated photooxidation resulted in inc

192 ls with the superoxide generators menadione, paraquat, or buthionine sulfoximine down-regulates c-FLI

193 non-transgenic mice were exposed to saline, paraquat, or the combination of paraquat + maneb twice a

194 RGC5 cells against TNFalpha cytotoxicity and paraquat oxidative stress.

195 lasmic diphenyleneiodonium-sensitive NAD(P)H:paraquat oxidoreductase.

196 ution of the well-known cyclophane, cyclobis(paraquat-p-phenylene) (BB(4+) ), and two cucurbit[7]uril

197 ability of the diradical dicationic cyclobis(paraquat-p-phenylene) (CBPQT(2(*+))) ring to form inclus

198 rings of the bipyridinium units in cyclobis(paraquat-p-phenylene) (CBPQT(4+) or "blue box") and desc

199 otion of the ring-shaped component, cyclobis(paraquat-p-phenylene) (CBPQT(4+)) (denoted as the ring),

200 g interactions taking place between cyclobis(paraquat-p-phenylene) (CBPQT(4+)) and five different mon

201 )) generated by the complexation of cyclobis(paraquat-p-phenylene) (CBPQT(4+)) and the guest molecule

202 dox-active rotaxanes, which drove a cyclobis(paraquat-p-phenylene) (CBPQT(4+)) mobile ring between a

203 pyridinium (P-BIPY(2+)) unit and a cyclobis (paraquat-p-phenylene) (CBPQT(4+)) ring component.

204 istable [2]rotaxane consisting of a cyclobis(paraquat-p-phenylene) (CBPQT(4+)) ring encircling a dumb

205 s mechanically interlocked with the cyclobis(paraquat-p-phenylene) (CBPQT(4+)) ring has also been pre

206 The location of the two cyclobis(paraquat-p-phenylene) (CBPQT(4+)) rings can be controlle

207 nes formed between these stalks and cyclobis(paraquat-p-phenylene) (CBPQT(4+)) rings, and (c) bistabl

208 us series of [2]rotaxanes, in which cyclobis(paraquat-p-phenylene) (CBPQT(4+)) serves as the ring com

209 aphthalene (DNP) units encircled by cyclobis(paraquat-p-phenylene) (CBPQT(4+)), a pi electron-accepti

210 on a tetracationic cyclophane host, cyclobis(paraquat-p-phenylene) (CBPQT(4+)), and a 1,5-dioxynaphth

211 otion of the ring-shaped component, cyclobis(paraquat-p-phenylene) (CBPQT(4+)), between a monopyrrolo

212 ous hosts-cucurbit[7]uril (CB7) and cyclobis(paraquat-p-phenylene) (CBPQT(4+)), respectively-using th

213 with the tetracationic cyclophane, cyclobis(paraquat-p-phenylene) (CBPQT(4+)), was synthesized by do

214 y with the tetracationic cyclophane cyclobis(paraquat-p-phenylene) (CBPQT(4+)), were obtained by dono

215 We find that the orientation of the cyclobis(paraquat-p-phenylene) (CBPQT) ring depends dramatically

216 ur donor-acceptor [2]catenanes with cyclobis(paraquat-p-phenylene) (CBPQT4+) as the pi-electron-accep

217 station, and (iii) a tetracationic cyclobis(paraquat-p-phenylene) (CBPQT4+) pi-electron-acceptor cyc

218 cled by a tetracationic cyclophane, cyclobis(paraquat-p-phenylene) (CBPQT4+), contrary to what is obs

219 e unit, interlocked mechanically by cyclobis(paraquat-p-phenylene) as its tetrachloride, exists as a

220 onor-acceptor [2]catenanes based on cyclobis(paraquat-p-phenylene) as the pi-acceptor ring have been

221 ely strong inclusion complexes with cyclobis(paraquat-p-phenylene) in its diradical dicationic redox

222 The 'blue box' (cyclobis(paraquat-p-phenylene) or CBPQT(4+)), developed by Stodda

223 tristable [2]rotaxane composed of a cyclobis(paraquat-p-phenylene) ring and a dumbbell with tetrathia

224 d bistable [2]rotaxane containing a cyclobis(paraquat-p-phenylene) ring and tetrathiafulvalene/1,5-di

225 rown ether occupies the cavity of a cyclobis(paraquat-p-phenylene) ring and the other in which a 1,5-

226 The cyclobis(paraquat-p-phenylene) ring in the [2]rotaxane can be swi

227 Altering the redox state of a cyclobis(paraquat-p-phenylene) ring simultaneously (i) inverts th

228 sed of two mechanically interlocked cyclobis(paraquat-p-phenylene) rings has been obtained from the o

229 eptor [3]catenane incorporating two cyclobis(paraquat-p-phenylene) rings linked together by a dinapht

230 sed of two mechanically interlocked cyclobis(paraquat-p-phenylene) rings-with "zero", one, and two mo

231 ane composed of two rigid and fixed cyclobis(paraquat-p-phenylene) rings.

232 is [2]rotaxane, which consists of a cyclobis(paraquat-p-phenylene) shuttle (CBPQT(4+))(PF(6)(-))(4) (

233 on of the tetracationic cyclophane, cyclobis(paraquat-p-phenylene), and the radical cation generated

234 xtensively studied macrocyclic host cyclobis(paraquat-p-phenylene)--the so-called "blue-box"--it is s

235 ' (BB(4+)) tetracationic cyclophane cyclobis(paraquat-p-phenylene).

236 with the discovery that MV(+*) and [cyclobis(paraquat-p-phenylene)](2(+*)) (CBPQT(2(+*))) form a stro

237 Patients with acute paraquat poisoning were recruited.

238 seful prognostic marker of death after acute paraquat poisoning.

239 Paraquat (PQ(2+)) is a prototypic toxin known to exert i

240 Paraquat (PQ) causes selective degeneration of dopaminer

241 The herbicide paraquat (PQ) has increasingly been reported in epidemio

242 ttent (biweekly) exposure to intraperitoneal Paraquat (PQ) plus Maneb (MB).

243 function sigma(M) protein, was sensitive to paraquat (PQ), a superoxide-generating reagent, but not

244 ree different isolates of P. aeruginosa with paraquat (PQ), a superoxide-producing agent.

245 ntal oxidative stressors, like the herbicide paraquat (PQ), has been linked to the development of Par

246 Exposure to paraquat (PQ), hydrogen peroxide, or organic peroxides s

247 Here, using paraquat (PQ)-based in vitro and in vivo PD models, we s

248 as a model organism, we report the effect of paraquat (PQ)-induced OS on wild type worms on the funct

249 H2O2 induced intramitochondrial O2-, whereas paraquat produced O2- outside of the mitochondria, and t

250 or NADPH, and readily generates the reduced paraquat radical.

251 in reductase or recombinant enzyme possessed paraquat reductase activity.

252 Purified paraquat reductase from the cells contained thioredoxin

253 ated overexpression of Sod2 neither enhances paraquat resistance in Sod1+ flies nor compensates for l

254 complemented the SNO-dependent phenotypes of paraquat resistant 2-1 (par2-1) plants but not the NO-re

255 od LOQ was 10 and 20mugkg(-1) for diquat and paraquat, respectively.

256 The administration of paraquat resulted in significantly higher 24-h mortality

257 rythroid progenitor cells by the pro-oxidant Paraquat reversed the effect of UCP2 deficiency on cell

258 confers tolerance against stress induced by Paraquat, Rose Bengal, heavy metal, and the synthetic au

259 with the oxidative stress-producing reagent paraquat showed a breakdown of sleep:wake cycles similar

260 On the other hand, paraquat showed average recoveries between 68 and 103% w

261 DJ-1-deficient mice treated with paraquat showed decreased proteasome activities and incr

262 elta sodA1) had transcriptional responses to paraquat similar to, but notably larger than, those of t

263 anipulations did not increase sensitivity to paraquat, sodium azide, divalent metal ions (Fe(II) or C

264 onionic pollutants were highly linear, while paraquat sorption was strongly concentration dependent.

265 Binding of two different 4,4'-bipyridinium (paraquat) species (3) and 2,2'-bipyridinium (diquat) 4 b

266 al of dopaminergic neurons and resistance to paraquat stress, but showed acute sensitivity to hydroge

267 he ROS-generating herbicide methyl viologen (paraquat), suggesting a common protective role for proli

268 reated cultures, but not in those exposed to paraquat, suggesting that this response involves a speci

269 ss adaptation and produces the male-specific paraquat (superoxide) stress adaptation.

270 ress, whereas males but not females adapt to paraquat (superoxide) stress.

271 's disease in males, male Drosophila exhibit paraquat symptoms earlier than females.

272 nding constant (Ka = 2.4 x 10(5) M(-1)) with paraquats than the analogous dibenzo-30-crown-10-based c

273 owth traits under heat stress, arsenite, and paraquat, the majority of which were best explained by a

274 Under exposure to paraquat, the yggX deletion strain showed a deficiency i

275 ase protein were cultured in the presence of paraquat, there was a paraquat concentration-dependent i

276 n to the redox-cycling agents, menadione and paraquat; this reduced survival was accompanied by an ac

277 e.g. H(2)O(2), peroxynitrite, menadione, and paraquat) through transient alterations in gene expressi

278 ne, and 2-naphthol), and of the organocation paraquat to unreduced and electrochemically reduced Leon

279 subsequent pro-apoptotic insults and reduces paraquat toxicity in Drosophila.

280 ne protein that has been shown to counteract paraquat toxicity in other experimental models and could

281 dopaminergic neurons protects flies against paraquat toxicity in vivo, ameliorating defects in dopam

282 uclein within nigral dopaminergic neurons of paraquat-treated and alpha-synuclein-overexpressing anim

283 ting against the oxidative damage induced by paraquat treatment, our data demonstrated that in Drosop

284 levels was examined by using heat stress and paraquat treatment.

285 yperresponsive to oxidative damage caused by paraquat treatment.

286 are sensitive to oxidative stress induced by paraquat treatment.

287 o cell death induced by rotenone, MPP(+), or paraquat treatments, the absence of complex I activity d

288 in wild-type worms using ethidium bromide or paraquat triggered statin resistance, and similar observ

289 pts a folded conformation, where each of two paraquat units remain sandwiched between the two aromati

290 Detailed (1)H NMR studies revealed that two paraquat units were bound cooperatively by the two crown

291 exposure of M17 cells to the oxidizing agent paraquat was manifested as a shift in pI of endogenous D

292 Tolerance to Cu, Zn and paraquat was unaffected by MT deficiency but these plant

293 The highest concentrations of paraquat were seen in the pineal gland and the lateral v

294 asts are more sensitive to streptonigrin and paraquat when deleted for Ku80 as compared with Ku70.

295 nematode survival in response to rotenone or paraquat, which are agents that cause mitochondrial dysf

296 Rearing mutants on paraquat, which generates toxic free radicals in vivo, c

297 nitrogen species (RNS) generator, and 0.5 mM paraquat, which produces reactive oxygen species (ROS),

298 ence links chronic exposure to the pesticide paraquat with the incidence of the disease, most probabl

299 d the heart from oxidative stress induced by paraquat, with increased expression of antioxidants, suc

300 PH oxidase inhibitor, blocked the effects of paraquat without altering mitochondrial respiration.