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3 DNA sequencing analysis) with those from the parasitologic approach (in vitro culture followed by iso
6 sistant P. falciparum did not exacerbate any parasitologic, histologic, or clinical measures of PAM m
8 ion), and was not associated with an adverse parasitologic outcome in any of the gene-targeted mouse
11 r the primary outcome: adequate clinical and parasitologic response in the per-protocol population on
12 ain reaction-corrected adequate clinical and parasitologic response on day 28, parasite clearance tim
14 dence interval [CI], 0.47-0.93; P=.02) or in parasitologic treatment failure on day 7 (RR, 0.51; 95%
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