ライフサイエンスコーパス: parent-of-origin effect

1 loci for asthma and AR while accounting for parent-of-origin effect.

2 logarithm of odds (LOD) 2), with a prominent parent-of-origin effect.

3 rted association in the region, again with a parent-of-origin effect.

4 es this pathway through a previously unknown parent-of-origin effect.

5 on of any tSNP to affected offspring or of a parent-of-origin effect.

6 phytic genes, some of which are subject to a parent-of-origin effect.

7 nner explicable by genome dosage rather than parent of origin effects.

8 /control studies and allows the detection of parent-of-origin effects.

9 igator may wish to look further for possible parent-of-origin effects.

10 at reside at nonimprinted loci but that show parent-of-origin effects.

11 portance, it is crucial to account for these parent-of-origin effects.

12 alignment of pulmonary veins (ACD/MPV), with parent-of-origin effects.

13 requent mosaicism, inconsistent activity and parent-of-origin effects.

14 imary insulin resistance and HCC with strong parent-of-origin effects.

15 disease (AD) pathology and whether there are parent-of-origin effects.

16 ed lethality and directly test for loci with parent-of-origin effects.

17 ence for any susceptibility locus subject to parent-of-origin effects.

18 provide insight into maternally mediated and parent-of-origin effects.

19 5, 62% transmission, P = 7 x 10(-5)) with no parent-of-origin effects.

20 an genome, providing insights into potential parent-of-origin effects.

21 of genetic and environmental mechanisms for parent-of-origin effects.

22 ility risk, on the basis of such evidence as parent-of-origin effects.

23 The likelihood formulations model parent-of-origin effect and allow for incorporation of a

24 susceptibility is characterized by maternal parent-of-origin effects and increased female penetrance

25 shown to influence disease severity, display parent-of-origin effects and interact with a major envir

26 t-offspring "trio" design was used to assess parent-of-origin effects and population stratification.

27 action of IDDM2 is complicated, however, by parent-of-origin effects and possible allelic heterogene

28 maternal versus paternal transmission rates (parent-of-origin effects) and nontransmission rates (non

29 suggest an important role for methylation in parent-of-origin effects, and by inference parental impr

30 Maternal-offspring HLA compatibility, parent-of-origin effects, and NIMA effects at DRB1 are u

31 igated maternal-offspring HLA compatibility, parent-of-origin effects, and NIMA effects at DRB1 in SL

32 candidate genes for complex conditions where parent-of-origin effects are involved, including Alzheim

33 Parent-of-origin effects are prominent at some of the lo

34 ct4 on CHR X, was demonstrated with a strong parent-of-origin effect associated with the paternal gen

35 However, the molecular basis for the parent-of-origin effect associated with trinucleotide re

36 2 microdeletion region, suggesting potential parent-of-origin effects associated with this genomic di

37 19q12 loci as RET-dependent modifiers, and a parent-of-origin effect at RET.

38 We found suggestive evidence of a parent-of-origin effect at the ABO locus by analyzing th

39 e a further characterization of the possible parent-of-origin effects at the 17q11 locus that were pr

40 multinomial modeling approach for estimating parent-of-origin effects at the test SNP.

41 consequent interest in seeking evidence for parent-of-origin effects at these loci.

42 Several phenomena can cause parent-of-origin effects, but the best characterized is

43 vidence that nonimprinted genes can generate parent-of-origin effects by interaction with imprinted l

44 ased when analyzed with a model allowing for parent-of-origin effects, compared with analyses that as

45 r offspring point to quantitative epigenomic parent-of-origin effects confounding classical Mendelian

46 Parent-of-origin effects create differences in gene expr

47 The imprinted gene and parent-of-origin effect database (www.otago.ac.nz/IGC) c

48 a catalogue of de novo mutations that show a parent-of-origin effect expands the scope of the databas

49 These data strongly refute a parent-of-origin effect for 1p deletions in NB and exclu

50 backcross scheme that exploited a paternal, parent-of-origin effect for a X-linked gene (Gct4) that

51 linear models can be used to estimate these parent-of-origin effects for a broad class of phenotypes

52 We analyzed parent-of-origin effects for these variants, along with

53 hybrids that showed differential phenotypes (parent-of-origin effect) for CG or DT were selected for

54 Parent-of-origin effects have been difficult to screen f

55 Parent-of-origin effects have been reported for type 2 d

56 hould provide a powerful diagnostic tool for parent of origin effects in the study of aneuploidy, imp

57 No parent-of-origin effect in allelic expression was found

58 We sought to investigate the parent-of-origin effect in childhood allergic diseases.

59 ed a likelihood-based method for testing for parent-of-origin effect in complex diseases.

60 dering ascertainment models when testing for parent-of-origin effect in complex diseases.

61 of genetic analyses, taking into account the parent-of-origin effect in families ascertained through

62 Furthermore, the lack of parent-of-origin effect in LQT syndrome appears to be du

63 The difference in risk suggests a maternal parent-of-origin effect in multiple sclerosis susceptibi

64 0 other entries describe a range of reported parent-of-origin effects in animals.

65 to the sexual dimorphism in EAE and paternal parent-of-origin effects in female mice, raising the pos

66 Thus, our study reveals parent-of-origin effects in heritable insulin resistance

67 urther research on familial transmission and parent-of-origin effects in LOAD.

68 500 genes exhibit statistically significant parent-of-origin effects in maize endosperm tissue, but

69 This study confirms parent-of-origin effects in the association with type 2

70 testing for maternally mediated effects and parent-of-origin effects in the same framework.

71 fie and mea mutations also cause parent-of-origin effects, in which the wild-type materna

72 We also observe two types of parent-of-origin effects, including classical imprinting

73 In this study, we questioned whether parent-of-origin effects influence EAE, using reciprocal

74 For example, both allelic variation and parent-of-origin effects influence the thymic expression

75 Methods are presented for incorporation of parent-of-origin effects into linkage analysis of quanti

76 This parent-of-origin effect is due to Gsalpha imprinting in

77 The parent-of-origin effect is important in understanding th

78 However, the basis for the parent-of-origin effect is unknown.

79 icentromeric region of chromosome 18, with a parent-of-origin effect (linkage was present in pedigree

80 Parent-of-origin effects occur when the phenotypic effec

81 JL Gct4 allele (Gct4(J)) also shows a strong parent-of-origin effect, occurring only when the Gct4(J)

82 nd maternal effects as the cause of apparent parent-of-origin effects of alleles.

83 the molecular mechanism responsible for the parent-of-origin effects of mea mutations on seed develo

84 Thus, parent of origin effects on sharing and linkage to impri

85 some multicopy genes influences the paternal parent-of-origin effect on EAE susceptibility in female

86 e plants show that DNA hypomethylation has a parent-of-origin effect on seed size.

87 No evidence was found for parent-of-origin effects on allelic transmission.

88 s (PO) and Peromyscus maniculatus (BW) yield parent-of-origin effects on both embryonic and placental

89 45,XO) has suggested that there are X-linked parent-of-origin effects on brain development and cognit

90 s usually result in viable seed that exhibit parent-of-origin effects on endosperm development and fi

91 n, DECREASE IN DNA METHYLATION1, also causes parent-of-origin effects on F(1) seed size.

92 l3 to be paternally imprinted, with profound parent-of-origin effects on gene expression.

93 culatus (BW) and P. polionotus (PO), produce parent-of-origin effects on growth and development.

94 rinting represents a mechanism through which parent-of-origin effects on offspring development may be

95 n, indicate that fie and mea mutations cause parent-of-origin effects on seed development by distinct

96 t although Brassica oleracea displays strong parent-of-origin effects on seed development, triploid b

97 ing variability could contribute to observed parent-of-origin effects on seed development.

98 ion, we demonstrate that previously reported parent-of-origin effects on standing mRNA levels in Dros

99 and CF28, were found to trigger significant parent-of-origin effects on the age of femoral capital o

100 cies where imprinting is observed, there are parent-of-origin effects on the expression of imprinted

101 epigenetic modification that can result in 'parent-of-origin' effects on phenotypic traits.

102 Most existing methods for investigating parent-of-origin effects operate on a SNP-by-SNP basis a

103 No parent-of-origin effect or somatic instability was obser

104 hole, nor was there evidence for significant parent-of-origin effect (pedigrees with paternal transmi

105 The results suggest that parent-of-origin effects, perhaps including genomic impr

106 ca homologues of Arabidopsis genes linked to parent-of-origin effects revealed conservation of some m

107 rt reviews existing methods for detection of parent-of-origin effects, showing that each can be inval

108 ability, including expansions, deletions and parent-of-origin effects, somatic and early embryonic in

109 s also primarily caused by genetic loci with parent-of-origin effects, suggesting a possible role for

110 just one) are 'neutralized' with respect to parent-of-origin effects supports the hypothesis that pa

111 n outbred mice, that most phenotypes display parent-of-origin effects that are partially confounded w

112 Parent-of-origin effects thus provide new avenues for in

113 f nearly all genes analyzed, suggesting that parent-of-origin effect was minimal.

114 A parent-of-origin effect was observed, but it was not con

115 Additionally, evidence for parent-of-origin effects was observed.

116 ariance, the expected LOD score was 4.5 when parent-of-origin effects were incorporated into the anal

117 Significant parent-of-origin effects were observed in affected femal

118 Parent-of-origin effects were observed in an Icelandic p

119 Statistically significant (P < 0.05) parent-of-origin effects were seen for association with

120 Thus, parent-of-origin effects were specified within the autos

121 A polymorphism in Fc epsilon RI-beta shows parent-of-origin effects when associated with severe inf

122 indings suggest that divergence in loci with parent-of-origin effects, which is probably driven by ge

123 We found both deletions showed a parent-of-origin effect with 100% embryonic lethality wh

124 The ability to include parent-of-origin effects within linkage analysis of quan