ライフサイエンスコーパス: partial

1 such an account of their occurrence is only partial.

2 assified as grade 0 (none), 1 (marginal), 2 (partial), 3 (segmental), or 4 (necrotic) as previously d

3 ponse rate for arm B was 60% (complete, 10%; partial, 50%), which is higher than the 43.3% for arm C.

4 Partial ablation of the nail created pores that extended

5 s for alphaIIbbeta3 have been shown to cause partial agonism, leading to the opposite pharmacological

6 The dopamine partial agonist aripiprazole is increasingly used to tre

7 2 is associated with surface AMPARs, CNQX, a partial agonist at AMPARs associated with Type I TARPs,

8 /2A (100% response compared with glycine), a partial agonist at GluN1/2B and GluN1/2D (10% and 27%, r

9 from an antagonist for cell migration and a partial agonist in other assays to a full agonist in all

10 Unlike Rosi, VSP-51 is a partial agonist of PPARgamma with improved insulin sensi

11 aspartate (NMDA) modulator with glycine-like partial agonist properties; like the NMDA receptor antag

12 The TAAR1 partial agonist RO5263397 also promoted wakefulness and

13 nt, mice were given three doses of the TAAR1 partial agonist RO5263397, caffeine, or vehicle p.o.

14 We engineered a mechanism-based SCF partial agonist that impaired c-Kit dimerization, trunca

15 4-phenylthiomorpholin-1-ium triflate, a weak partial agonist with a sulfonium isostere of the ammoniu

16 and UCB35625 that act either as antagonist, partial agonist, or full agonist according to the recept

17 Partial agonists of PPARgamma, such as INT131 (1), have

18 Weak partial agonists that promote a desensitized state of th

19 uM, while others were weaker antagonists (or partial agonists) on these receptors.

20 t KOP receptor selectivity acting as full or partial agonists, and one as an antagonist.

21 e undesirable side effects, and provide only partial amelioration of negative and cognitive symptoms.

22 time window in early postnatal life wherein partial amputation culminates in a localized regeneratio

23 e, we examined genomewide DNA methylation in partial and complete loss-of-function met1 mutants.

24 mary outcome); serious or nonserious events; partial and complete remission of the nephrotic syndrome

25 tients with NRAS and HRAS mutations showed a partial and complete response to cetuximab, respectively

26 neurons and compare its performance against partial and cross-correlations for different correlation

27 Our results also suggest parallels between partial and/or biased agonism in RTKs and G-protein-coup

28 ference ligands, spanning the range of full, partial, and inverse agonists.

29 Testing requirements can be a partial answer to these challenges.

30 the developing Drosophila eye, we found that partial APC/C inactivation severely inhibits retinal dif

31 eversibility of this process renders diploid partial apomicts evolutionarily short-lived, and results

32 There were no severe adverse events, and partial ARB decolonization was observed in 20/25 (80%) o

33 nnual volume alone likely contributes only a partial assessment of the volume-outcome relationship.

34 of approximately 67% of total whey protein, partial association of denatured whey protein with the c

35 use model of acute cholestatic liver injury, partial bile duct ligation (pBDL), with a novel longitud

36 linergic neurotransmission, persisted during partial blockade of gap junctions and were mediated, in

37 eratoma, one patient had a cystadenofibroma (partial borderline tumor), one patient had an androgenic

38 Recommendations Partial-brain fractionated radiotherapy with concurrent

39 y whole-breast radiotherapy and 40 Gy to the partial breast (reduced-dose group), or 40 Gy to the par

40 breast (reduced-dose group), or 40 Gy to the partial breast only (partial-breast group) in 15 daily t

41 Accelerated partial breast radiation treatment was completed in Febr

42 In December 2013, 9 years after accelerated partial breast radiation treatment, she experienced prog

43 group), or 40 Gy to the partial breast only (partial-breast group) in 15 daily treatment fractions.

44 r the reduced-dose group and p=0.016 for the partial-breast group, compared with the whole-breast rad

45 ity can be claimed for both reduced-dose and partial-breast radiotherapy, and was confirmed by the te

46 imilar adverse effects after reduced-dose or partial-breast radiotherapy, including two patient domai

47 ts (change in breast appearance [p=0.007 for partial-breast] and breast harder or firmer [p=0.002 for

48 r [p=0.002 for reduced-dose and p<0.0001 for partial-breast]) compared with whole-breast radiotherapy

49 tio, 1.02; 95% CI, 1.01-1.04; p = 0.004) and partial bundle compliance (incident rate ratio, 1.15; 95

50 Likewise, for every 10% increase in partial bundle compliance, patients had a 15% higher hos

51 , as we show, swordtail fish carrying only a partial but conserved ortholog share recombination prope

52 s ranging from premature leaf senescence and partial canopy dieback to whole-tree mortality reduce ca

53 Here, we present a method that allows partial cation exchange in colloidal CsPbBr3 NCs, whereb

54 Here, we demonstrate a versatile partial cation exchange method to fabricate lamellar Ag-

55 ogy of the nanoheterostructures, formed upon partial cation exchange reactions, is intimately connect

56 ignancy; however to date there has only been partial characterization of MYC co-operative mutations l

57 Judging from partial charge analysis, we find that the hydrogen bond

58 We propose a novel second-order partial-charge interaction network which enables the cor

59 atomic overlap distance complements computed partial charges by measuring the size of orbital lobes t

60 Their partial co-localization with canonical endosomal markers

61 d using steady-state visual evoked potential partial coherence before and 90 minutes after the admini

62 1 using Scheimpflug technology combined with partial coherence interferometry (Pentacam AXL) and 1 us

63 ith facets of addictive behavior, supporting partial coincident neurological underpinnings for compul

64 patients according to the need for elective partial colectomy.

65 ally are detected within 100 mus before the partial collapse of the high pressure gradient boundary

66 has been growing interest in identifying the partial contributions of each of these stressors to prog

67 er associated gene dependencies and identify partial copy-loss of wild-type SF3B1 as a novel, non-dri

68 nal data, we developed a new Debiased Sparse Partial Correlation algorithm (DSPC) for estimating part

69 erior parietal cortex, as well as a positive partial correlation between treatment success (indexed b

70 Correlation algorithm (DSPC) for estimating partial correlation networks and implemented it as a Jav

71 ead, we find that the method based on robust partial correlations is generally more robust across a r

72 No partial correlations with treatment success have been fo

73 uding CIBERSORT and a method based on robust partial correlations.

74 y detailed analysis, we demonstrate that the partial CT in this weakly interacting mixture does not h

75 Despite the partial defect in both GEF and GAP regulation, KRAS K104

76 extractability is believed to be linked with partial degradation and opening-up of cell wall networks

77 mice Env(+)B cell clones develop anergy and partial deletion at the transitional to mature B cell st

78 ntified only in PN262000N21, while genes for partial denitrification occurred in both genomes.

79 ants (SDIs) (4.0 to 4.5 mm) supporting fixed partial dentures (FPDs) in posterior mandibular and maxi

80 content of SSA particles ranged from full to partial depletion, with 24% of SSA particles containing

81 en for the most remote attachment, costs for partial desolvation of the polar group next to the prote

82 , and in vitro differentiation promotes only partial development of this mechanism.

83 We formulated a minimal one-dimensional partial differential equation model that reproduced the

84 that captures intracellular dynamics through partial differential equation models.

85 uous spatiotemporal dynamical evolution from partial differential equations.

86 We demonstrate that partial direct reprogramming of mesoderm-derived cardiom

87 layer, and proceeded with the emission of a partial dislocation in between these two stacking faults

88 es subsequently interact and evolve with the partial dislocations, which migrate from domain to domai

89 for upregulation of p21 and EMT indicating a partial divergence between TGFbeta and MEK/ERK in early

90 ially complete (including 'Mnola') and three partial draft genomes (including Trichomonas vaginalis).

91 RA signaling in the dorsal domain results in partial duplication of the mandible.

92 ial fibrillation or flutter and six cases of partial electrical reset.

93 Using a rat model of PD, partial elimination of the functional interaction betwee

94 uid phase separation, leading to complete or partial engulfing of a hygroscopic particle core by a hy

95 for direct construction on muskeg, a mix of partial excavation and gradual compaction with the strat

96 reduction of the gain of feature tuning for partial face stimuli compared to whole face stimuli.

97 that the averaged N rate, grain yield and N partial factor productivity (PFPN) of the farmers were 3

98 of rotator cuff tears and in differentiating partial from complete tears.

99 s dual concept, we developed agents exerting partial FXR agonism and sEH inhibitory activity.

100 ts are needed to impart full efficacy to the partial GABA agonists.

101 ated HX-associated PIEZO1 variants exhibit a partial gain-of-function phenotype with generation of me

102 Site-directed mutagenesis was performed by partial gene synthesis, and enzymes were overproduced fr

103 on an unbiased genetic screen, we found that partial genetic and pharmacological inhibition of fatty

104 A), the combination of genomic imbalance and partial genome loss disrupts the normal pattern of embry

105 Autosomal recessive, partial GINS1 deficiency impairs DNA replication and und

106 synthesis of conjugated linoleic acid (CLA) partial glycerides, which presented nutraceutical proper

107 Selected mutations also lead to partial glycosylation of N582, suggesting that rapid fol

108 d insulin independence, 6 patients (56%) had partial graft function, and 1 patient (9%) had primary g

109 In childhood, partial hearing loss can produce prolonged deficits in s

110 point was complete remission (CR) or CR with partial hematologic recovery (CRh) during the first two

111 were transplanted via splenic injection into partial hepatectomized DPPIV- rats that had been pretrea

112 models of liver regeneration after extended partial hepatectomy and portal vein ligation for multipl

113 lectively augmented liver regeneration after partial hepatectomy and portal vein ligation, and increa

114 hydatidiform moles and diandric triploid in partial hydatidiform moles) is a fundamental genetic eve

115 Much slower dynamics, up to partial immobilization of the organic cation, are observ

116 needs full implementation and their combined partial implementation delivers a more sustainable food

117 hain gas stations (1.31 cent/oz, p = 0.004), partial in pharmacies (+0.45 cent/oz, p = 0.03), and neg

118 r adequate forces to drive the process, that partial inhibition of branching and polymerization lead

119 hythmia in human ventricles, and establishes partial inhibition of IKs as a potential anti-arrhythmic

120 isticated approaches that allow also for the partial integration of land management changes.

121 the small-molecule CD11b agonist LA1 led to partial integrin activation, reduced IFN-I responses in

122 Using orthogonal partial last-squares discriminant analysis (OPLS-DA), mu

123 Partial least square (PLS) regression models confirmed r

124 n detection algorithms were combined using a partial least square classifier to determine the presenc

125 upled with different classification methods (Partial Least Square Discrimination Analysis "PLS-DA" an

126 f EVOOs was satisfactory predicted through a partial least square model based on DeltaK, hydroxytyros

127 k include Martens Uncertainty test, interval Partial Least Square Regression (iPLS) and Genetic Algor

128 erence materials (i-HRM) using two different Partial Least Square-Regression (PLS-R) multivariate qua

129 ies and specific chemometrics tools, such as partial least squares (PLS), interval-PLS, synergy inter

130 A multilevel, within-group, sparse partial least squares analysis of covariation of microbi

131 ween each two groups were obtained using the partial least squares discriminate analysis of 9 lipid m

132 For all fibroblast strains combined, the partial least squares-linear discriminant analysis (PLS-

133 Partial least-squared discriminant analysis (PLS-DA) wit

134 The partial least-squares discriminant analysis (PLS-DA) mod

135 uding principal-component analysis (PCA) and partial least-squares discriminant analysis (PLSDA), wer

136 riable importance measurements obtained from partial least-squares discriminant analysis models.

137 onance (NMR) profiles were analyzed by using partial least-squares discriminant analysis, and the res

138 he PARAFAC components were used to develop a partial least-squares regression-based model (r(2) = 0.5

139 Notably, using partial least-squares-path modeling we found that WM ins

140 maintains compartment size at the expense of partial loss in stemness and incomplete differentiation

141 with hyperactivated Wnt signaling caused by partial loss of axin, a key component of the Wnt cascade

142 We demonstrate that partial loss of p85alpha increases the amount of p110alp

143 spread, which is evident even in cells with partial loss of SPCA1.

144 Recently, a novel partial loss-of-function AKT2 coding variant (p.Pro50Thr

145 Multiple doses of ivermectin have a partial macrofilaricidal and a modest permanent steriliz

146 Partial Mantel tests supported our hypothesis of incipie

147 e cavity shave margins (CSM) versus standard partial mastectomy (PM) in patients with breast cancer.

148 iorite rocks (TTGs) that were formed through partial melting of hydrated low-magnesium basaltic rocks

149 related benefits of migration, we studied a partial migratory population of European blackbirds (Tur

150 plex neurocognitive mechanisms which lead to partial mimicry but are also likely to be influenced by

151 We present partial mitochondrial genomes from one S. populator samp

152 weathering in a warm climate and subsequent partial mobilization of the saprolitic mantle into the o

153 Therefore, standard partial molar volumes at infinite dilution have been cal

154 e 2 complete molecular responses (CMR) and 1 partial molecular response in CALR-positive ruxolitinib-

155 It is not clear how using partial-mouth periodontal examination (PMPE) protocols a

156 mouth and is classified as either a full or partial muscarinic agonist.

157 stage 4 or higher after radical (n=9759) or partial nephrectomy (n=4370) was 7.9% overall.

158 Partial nephrectomy (PN) for SRMs is the standard treatm

159 Finally, patients treated with a partial nephrectomy had reduced risk of mortality (hazar

160 The comparative effectiveness of partial nephrectomy versus radical nephrectomy to preser

161 Partial neuromuscular blockade facilitates lung-protecti

162 Partial nitritation and Anammox processes are increasing

163 Partial nitritation/anammox can provide energy-efficient

164 ectral location of the affected amide peaks, partial NMR assignments, and JM mutants (ST(296)AA or T(

165 of full mitochondrial genomes from four and partial nuclear genomes from two P. antiquus fossils.

166 Moreover, ACOT1 exhibited partial nuclear localization during fasting and cAMP/cAM

167 sequences, including canonical, diverse and partial ones, were delineated from all 19 accessions.

168 ublingual buprenorphine-naloxone (BUP-NX), a partial opioid agonist, are pharmacologically and concep

169 nic transdifferentiation program that allows partial or complete transition from an epithelial to a m

170 participants who received at least one dose (partial or complete) of study drug.

171 ith respect to complete remission with full, partial, or incomplete hematologic recovery (44% vs. 25%

172 g factor (0 </= alpha </= 1) as an apparent, partial order with respect to the probe to measure the "

173 Even though auxiliary partial orthotopic liver transplantation (APOLT) as a te

174 the relevant reptiles, our results suggested partial overlap of their temporal niches during crepuscu

175 the Ag nanoparticles typically undergo only partial oxidation prior to diffusing away from the Au el

176 ed high-rate, high-yield N2O production with partial P removal.

177 Two calibration stages were explored, partial (P1), where experimental dry matter data were no

178 effectively blocks transformation driven by partial p85alpha loss both in vitro and in vivo.

179 Here we used long-term partial pancreatic duct ligation (PDL) as a model to stu

180 s were randomly assigned to DPPHR (n=125) or partial pancreatoduodenectomy (n=125), of whom 226 patie

181 ients (115 in the DPPHR group and 111 in the partial pancreatoduodenectomy group) were analysed.

182 treatment were randomly assigned to DPPHR or partial pancreatoduodenectomy with a central web-based r

183 pancreatic head resection (DPPHR) than after partial pancreatoduodenectomy.

184 The partial Pb(2+) for M(2+) exchange leads to a blue-shift

185 We calculated partial Pearson correlations between 617 metabolites and

186 bellar foliation defects, motor impairments, partial pontine nucleus migration defects, cochlear hair

187 s indicate that increased stabilization of a partial positive charge on the nitro-substituted carbon

188 AS mutant melanomas, an effect driven by the partial preservation of negative feedback loops.

189 We measured arterial oxygen partial pressure continuously with a fast intra-vascular

190 Limitation of plant productivity by the low partial pressure of atmospheric CO2 (Ca ) experienced du

191 ) after hyperoxia was converted to change in partial pressure of oxygen (DeltaPo2).

192 rements of intracortical (depth) EEG (dEEG), partial pressure of oxygen in interstitial brain tissue

193 stomatal conductance so as to allow the CO2 partial pressure within stomatal cavities and their intr

194 At 0.15 bar CO2 partial pressure, the CO2/N2 selectivity was 49 (corresp

195 ed temperatures (27, 30.3 degrees C) and CO2 partial pressures (pCO2 ) (400, 900, 1300 muatm).

196 The logarithm of BA partial pressures correlated significantly to reciprocal

197 lorophyll a (Chl-a) under present and higher partial pressures of atmospheric CO2 (pCO2 = 400 and 100

198 d the effect of hydrogen and carbon monoxide partial pressures on selectivity were measured.

199 egeneration), and reached 97 at ultralow CO2 partial pressures.

200 perimental apparatus based on changes of CO2 partial pressures.

201 n model of change in QoL at 3 months using a partial proportional odds model for no change, small, mo

202 ll protection provided stronger effects than partial protection.

203 e, we report the heterologous expression and partial purification of His-tagged CesA5 from Physcomitr

204 syndrome as young adults, and about 50% show partial, rather than complete, remission.

205 Our results show partial re-assimilation of CO2 and H2 by n-butanol-produ

206 some cancer types have been shown to exhibit partial recapitulation of bivalent chromatin modificatio

207 These findings allow for a partial reconstruction of the polychromy.

208 cale texture and isotopic analyses provide a partial record of the chemical reactions that occurred i

209 sensitivity was attenuated, accompanied by a partial recovery of Kv4.3, KChIP1, and DPP10 surface lev

210 Partial recurrence was observed during follow-up in a pa

211 We show a partial rediploidization represented by a complex mosaic

212 Postcolumn partial reduction by ISR provided fast and easy identifi

213 logy to use as an online and fully automated partial reduction procedure.

214 henotypic severity over males (MKOs), due to partial redundancy with UTY, a Y-chromosome demethylase-

215 of glutenins up to 80 degrees C, followed by partial refolding and aggregation at even higher tempera

216 mplete haematological recovery, and 25 (10%) partial remission INTERPRETATION: Gilteritinib had a fav

217 Complete remission or partial remission was achieved in 247 patients (76%).

218 Although the cumulative incidence of partial remission was lower in the Rtx group, rates of c

219 with IIS resistance, complete remission, and partial remission, respectively; 27% in children with a

220 d sensory impact of sodium reduction and its partial replacement by potassium chloride in pizza dough

221 l within a Monte Carlo simulation framework, partial replacement of the LSL was predicted to result i

222 clerosis and Parkinson's disease, and show a partial rescue of the Parkinson's phenotype through drug

223 ups and adsorbed water in locations and with partial residence times consistent with experimentally d

224 pairs CD8(+) T-cell infiltration and confers partial resistance to immunotherapies.

225 (5m)C or (N6m)A into 9 g DNA as confirmed by partial resistance to restriction and by liquid chromato

226 mptoms attributed to ECD), partial response (partial resolution of symptoms attributed to ECD), stabl

227 the surrounding area for responders than in partial responders or nonresponders (mean +/- standard d

228 ), very good partial response (9 [19%]), and partial response (16 [33%]); median duration of response

229 red eleven of 126 patients had a complete or partial response (88%; 95% CI, 81% to 93%), of whom 88 h

230 sponse/complete response (4 [8%]), very good partial response (9 [19%]), and partial response (16 [33

231 e resolution of symptoms attributed to ECD), partial response (partial resolution of symptoms attribu

232 BCL who achieved a complete response (CR) or partial response (PR) to R-CHOP induction.

233 The rate of better than very good partial response (VGPR) was higher in more recent period

234 d clinical benefit rate (complete response + partial response + stable disease >/= 4 months), 43%.

235 roup analyses, participants who demonstrated partial response also experienced clinically meaningful

236 One patient achieved a partial response and experienced significant improvement

237 o relapsed was retreated and has remained in partial response for more than 23 months.

238 patients (9 adults and 7 children), 1 had a partial response for more than 9 months, 7 had stable di

239 .5%), major response in three (23.1%), and a partial response in three (23.1%) patients, whereas two

240 was 21% (14/66), and 15% achieved very good partial response or better (>/=VGPR).

241 The rates of overall response (partial response or better) were 82% (176/216) in the VR

242 of identified CAPS patients who show only a partial response to IL-1 blockade.

243 motherapy regimens, had achieved complete or partial response to their last platinum-based regimen, h

244 esponse for the four patients who achieved a partial response was 5.4 months (4.1 to 7.5 months).

245 1 of 17] complete response and 46% [8 of 17] partial response), with 18% (3 of 17) stable disease and

246 umors (grade 3 or 4) (complete response, 0%; partial response, 33%; SD or DP, 67%) (P < .001).

247 in 87% of patients (complete response, 49%; partial response, 38%; stable disease [SD] or local dise

248 Complete response, partial response, and stable disease as best response we

249 sponse will be defined as complete response, partial response, minor response, stable disease, or pro

250 Complete and partial response, stable disease, and progressive diseas

251 A relapse was defined as loss of partial response.

252 eported confirmed or unconfirmed complete or partial response.

253 one patient (6%; 95% CI 0.0-16.1) achieved a partial response.

254 econd course 1 month later for patients with partial response.

255 patients achieving an objective (complete or partial) response by central review after six cycles of

256 Antitumor activity (seven partial responses [six confirmed]) was demonstrated with

257 54 Gy radiation, and 20 (45%) with less than partial responses received 60 Gy.

258 There were 7 complete responses and 8 partial responses to combination carmustine and O6-benzy

259 24 (55%) patients with complete or partial responses to induction chemotherapy received 54

260 treated at the highest dose level, objective partial responses were observed in a patient with esopha

261 se rate was 77% (15 complete responses and 8 partial responses) in 30 evaluable patients.

262 onse, including one complete response and 21 partial responses.

263 There were two complete responses and seven partial responses.

264 equencing of nasopharyngeal samples produced partial sequences for 4 genome segments in one of these

265 disruption of nuclear envelope architecture, partial sequestration of factors essential for nucleocyt

266 ting of cascaded PV-converter modules, under partial shading conditions (PSCs).

267 A or anti-ActRIIB antibodies achieves only a partial signaling blockade upon myostatin or activin A s

268 c Regulation Of Metabolism (PROM) provides a partial solution, but it does not incorporate network in

269 physical model of the image formation under partial spatial coherence.

270 xchange mode), and more recently, discovered partial substrates.

271 Despite partial success, communication has remained impossible f

272 antial lowering of surface tension, even for partial surface coverage.

273 Many patients gained complete/partial symptom relief and substantially improved qualit

274 compared to smaller females, resulting in a partial temporal segregation between sexes.

275 d as an auxiliary method in the diagnosis of partial testicular torsion.

276 MRI detected 28 complete- and 12 partial-thickness tears of the rotator cuff.

277 Finally, the activated partial thromboplastin time (aPTT) coagulation assay was

278 th short prothrombin time (PT) and activated partial thromboplastin time (APTT) of 14.2 and 35.5s res

279 Longer activated partial thromboplastin time (hazards ratio, 0.98; p = 0.

280 with impaired liver function, and activated partial thromboplastin time confounding may interfere wi

281 ed tuberculosis and a clinically unsuspected partial thrombus in the splenic vein on imaging.

282 rential trabeculotomy (IMCT) vs conventional partial trabeculotomy (CPT) for primary congenital glauc

283 Here, we report that LTM can be induced by partial training after disruption of original consolidat

284 tion and H3K36 acetylation, and mutants show partial transcriptional overlap with set2 deletions.

285 Partial transformation of schwertmannite to goethite occ

286 Conclusion Conventional and partial UFE may be safe and effective outpatient procedu

287 In partial UFE, only the small arterial vessels to the fibr

288 Accordingly, partial 'un-scoring' of the problematic phylogenetic cha

289 from a preexisting salt bridge, initiating a partial unfolding event and promoting new protein intera

290 f chaperonin-mediated protein folding, where partial unfolding of misfolded intermediates plays a key

291 A partial vaccine series provided considerable protection,

292 cilitates lung-protective ventilation during partial ventilatory support, while maintaining diaphragm

293 Comparing the measured Fe partial vibrational density of states with density funct

294 e peripheral blood as an indirect measure of partial viral reservoir (Rho = 0.4580; P = 0.0030).

295 evaluate the impact of a joint-entropy based partial volume correction (PVC) technique on brain netwo

296 , they are susceptible to contamination from partial-volume blurring of tracer uptake in the cortex.

297 ost likely because of scanner resolution and partial-volume effects.

298 en type of gastric resection (ie, anatomic v partial/wedge) and EFS ( P = .67).

299 Knockdown of fidgetin is partial with this approach, but sufficient to increase t

300 ress this issue by generating 54 complete or partial ZIKV genomes, mostly from Brazil, and reporting