ライフサイエンスコーパス: partially

1 Sucrose was partially (50%) replaced by stevioside in formulations o

2 ition assays with human kinesin-5 (Eg5) only partially abrogated this behavior, indicating that Cin8

3 al esotropia, fully accommodative esotropia, partially accommodative esotropia, and all exotropia rev

4 hat differences in hospital quality may only partially account for readmission.

5 activates the alternate NO pathway which may partially account for the nitrite-mediated cardioprotect

6 se in the nucleation activity, which is only partially accounted for by the lack of the WH2 domain.

7 prediction and empirical observations can be partially accounted for using "compression heuristics",

8 ects in the STING DNA-sensing pathway, which partially accounts for the rescue of the DeltaICP0 virus

9 a modified GY94-type substitution model that partially accounts for this context dependency while pre

10 cally unstable tumors exhibit evidence for a partially activated DDR during mitosis, which leads to o

11 by the (R)-enantiomers, that are features of partially activated receptor conformations.

12 ge and amyloid on Abeta42 amplitude at least partially affect each other.

13 Furthermore, degradation could be partially affected by the ascorbate recycling pathway, a

14 t failure in mice, more robustly in DCM, and partially after transverse aorta constriction, by stabil

15 n of the nucleotide exchange factor Sse1 can partially alleviate this toxicity.

16 nd passive immunizations targeting alpha-syn partially ameliorate behavioral deficits and alpha-syn a

17 Succinate addition partially ameliorated these metabolic deficits.

18 g reward processes, with cocaine consumption partially ameliorating dependence-related insensitivity

19 ion and maturation stage of reprogramming in partially and fully reprogrammed cells respectively.

20 Then we analyzed partially and fully-refined oils from Italy, Tunisia and

21 ertheless, their etiology is understood only partially and the methods of causative treatment are lim

22 e carboxylate esters (SiPcs, 1-7) with non-, partially- and per-fluorinated aliphatic (linear or bran

23 21, and proposed that DS could be understood partially as an interferonopathy.

24 The evidence is now overwhelming that partially assembled nucleosome states (PANS) are as impo

25 ocytes exposed to HCV, and knockdown of TLR7 partially attenuated this expression, suggesting roles f

26 tures or in mouse lungs, and the disease was partially attenuated.

27 vascular risk observed in psoriasis would be partially attributable to an elevated subclinical corona

28 schizophrenia and substance use disorder is partially attributable to shared polygenic liability.

29 there are no effective treatments for HFpEF, partially attributable to the lack of well-established H

30 lmonary resuscitation performance, which can partially be explained by fewer unsolicited cardiopulmon

31 he male preponderant prevalence of ASD might partially be explained by sex differences in clinical sy

32 crease in matrix metalloproteinase (MMP) 13, partially because of enhanced LEF1 transcriptional activ

33 MSM not attending GUM clinics will partially benefit from herd protection.

34 ent structure, but in the complex it is only partially bent, with large-scale conformational changes

35 In conclusion, yerba mate polyphenols are partially bioavailable and extensively metabolized, main

36 This randomized clinical and partially blinded single-center trial was conducted in a

37 Patients and Methods This was a randomized, partially blinded, noninferiority trial that involved su

38 tober 2014, a prospective, replicate dosing, partially blinded, randomized, 3-treatment, 6-period cro

39 mance and related neurochemical changes were partially blocked by the PKG inhibitor KT 5823.

40 of redox-active species to the electrode is partially blocked by the substrate.

41 Strong evidence indicates that this partially burnt remnant was ejected following a sublumin

42 bens (NAc) and regulates motivated behaviors partially by activating NAc medium spiny neurons (MSNs).

43 ess in these two lines is patterned at least partially by distinct mechanisms.

44 semiconductive metals in dust particles and partially by hygroscopic properties.

45 susceptibility to subsequent refibrillation, partially by mitigating dysregulation of intracellular C

46 selectors mediate this restriction at least partially by organizing chromatin.

47 This bias can only be explained partially by the presence of fewer GR recognition sequen

48 genetic variation identified by trait GWASs partially captures environmental risk factors or protect

49 late that skepticism about climate change is partially caused by the spatial heterogeneity of climate

50 We now report that cytoplasmic DPPA3 is partially cleaved by the ubiquitin-proteasome system and

51 eviously revealed a dynamic exchange between partially closed and open conformations of the SAM-II ri

52 nins, namely, the roburins A, B and C, still partially coeluted, and their quantification was assiste

53 e largely present in individual clusters and partially colocalize at the presumptive fusion site.

54 ts and debris, although image processing can partially compensate for background signal.

55 omoting effect of E2F7/8 inactivation can be partially compensated via E2F1-dependent apoptosis.

56 As suspected, MoGlo3 partially complements the function of yeast Glo3p.

57 Patients with implants partially comply with scheduled SPT, regardless of perio

58 1 insertions originate from individuals with partially compromised piRNA defense.

59 e DNA polymerase function or MMR activity is partially compromised.

60 ncordant with the PMG in only 8 (16%) cases, partially concordant in 74%, and discordant in 10%.

61 g systems need to meet two complementary and partially conflicting goals: detecting regularities in t

62 These properties are partially conserved in primates, in which the relative a

63 (hiPSCs) contained functional gap junctions partially contributed by Connexin 45 (CX45).

64 and the secreted BPE005 protein, which were partially corroborated using the pharmacological inhibit

65 Partially customised birth weight centiles did not impro

66 Prediction of mortality between non- and partially customised birth weight centiles was compared

67 ds that predicted outcomes for both non- and partially customised birth weight centiles were calculat

68 The main exposures were noncustomised and partially customised birth weight centiles.

69 associations were observed for both non- and partially customised birth weight centiles.

70 oth phase-separate on cellulose surfaces and partially deconstruct Avicel (cellulose) in the absence

71 The DNA glycosylase ROS1 was only partially decreased in activity and xanthine dehydrogena

72 vealing clues as to how adult beta cells can partially dedifferentiate or become reprogrammed into ot

73 lves the mixed adsorption of O2 and H2O on a partially defected surface.

74 d hot spots on the plasma membrane, at least partially defined by the cytoskeleton and clathrin-coate

75 herapeutic indications and mechanisms remain partially defined.

76 Grafting molecular precursors on partially dehydroxylated silica followed by a thermal tr

77 appreciably alter protein synthesis and only partially delayed protein degradation as measured by a s

78 h and Li-poor phases are broadly observed on partially delithiated crystals, providing direct evidenc

79 d an electronic structure with an unexpected partially delocalized spin, as evidenced by electron par

80 The profibrotic phenotype of SFBLs partially depended on expression of CD26, but was indepe

81 Finally, we show that their biogenesis is partially dependent on a trans-acting factor FPA.

82 The endocytosis was clathrin dependent and partially dependent on beta-arrestin in HEK293 cells, an

83 ynamic VF movement and interactions at least partially dependent on intact microtubules.

84 This phenomenon was partially dependent on NF erythroid 2-related factor 2 (

85 was standing on its hindlimbs and which was partially dependent on the endogenous opioid system.

86 islets and the influx of CD11c(+) cells was partially dependent on their receptor Ccr5.

87 ts of ATB2 cells on glucose homeostasis were partially dependent upon T cells and macrophages.

88 those from different clusters play at least partially different roles.

89 Malabsorption of partially digested food causes bloating, overfilled inte

90 idase genes, resulted in the accumulation of partially digested xyloglucan subunits, such as GXXG, GX

91 as intrinsically disorder proteins (IDPs) or partially disordered segments known as intrinsically dis

92 several of the cancer-associated mutations, partially disrupt the POT1-TPP1 complex, which affects i

93 AV1-P158 functions as a dominant negative by partially disrupting WT CAV1 trafficking.

94 quantitatively explained by a model in which partially dissociated bound proteins are susceptible to

95 nal changes to compression and rotation of a partially dissociated gD dimer.

96 bril solution, highly viscous and stable, by partially dissolving silk fibers into microfibrils.

97 Correspondingly, partially distinct distributions of autoradiographic lab

98 ly, mechanisms regulating sickness sleep are partially distinct from those regulating healthy sleep.

99 R)50 and (GR)50 exert their toxicity through partially distinct mechanism(s).

100 Growth trends are - at least partially - driven by underlying recruitment or age dist

101 s and (ii) downregulation of beta-catenin is partially driving effects of Indomethacin in cisplatin-r

102 lity suggests the inhibition may be at least partially due to drag forces from weakly attached myosin

103 ce but remains challenging which is at least partially due to the lack of persistent and homogeneous

104 These findings at least partially explain how Ct infection could result in adver

105 x and bHLH transcription factors PIFs, would partially explain phytochrome-cryptochrome coactions.

106 ced early-stage sound level processing could partially explain the auditory processing deficits in FX

107 arly all aspects of immunity, which at least partially explain the increased susceptibility to infect

108 Lipid metabolites may partially explain the inverse association between the Me

109 eting by miR-6883-5p and miR-149* could only partially explain the observed antiproliferative effects

110 raphic heterogeneity in survival that can be partially explained by differences in distribution of he

111 rential methylation between ethnic groups is partially explained by the shared genetic ancestry but t

112 ial heterotrophic and nitrifying communities partially explained the variability in many biogeochemic

113 This association is currently only partially explained.

114 lowest among vertebrates analyzed to date - partially explains the discrepancy between the rather lo

115 and wild vervet monkeys respond strongly to partially exposed snake models and scale patterns on the

116 In task 2, we employed pictures of partially exposed snakes, lizards, and birds.

117 Mitochondrial flux from ASMCs to T cells was partially FGF2b and FGFR1 dependent.

118 Catalytic C-H bond silylation is facile with partially fluorinated aromatic substrates containing two

119 ted rhesus macaques from developing AIDS and partially from vaginal SIV acquisition.

120 ier to "indeterminate" samples (samples that partially fulfilled Banff criteria for AMR; n = 65) yiel

121 s essential for Pck1 function, Pck2 remained partially functional independent of its catalytic activi

122 ally defective in PulM interaction, remained partially functional.

123 based LOHC system composed of hydrogen-lean, partially hydrogenated, and fully hydrogenated forms.

124 of eight CM formulas, one nonhydrolyzed, two partially hydrolyzed (PH), four extensively hydrolyzed (

125 l trial investigating the effectiveness of a partially hydrolyzed protein formula supplemented with n

126 We showed that a partially hydrolyzed protein infant formula with specifi

127 nd pharmacologic inhibition of NADPH-oxidase partially impairs NET production.

128 colysis in all resistant cell lines but only partially improve the susceptibility of resistant PDACs

129 t weight problems in adulthood may be rooted partially in early childhood exposure to unpredictable e

130 ough their activation from a quiescent state partially in response to profibrotic growth factors.

131 We show that FANCI and FANCD2 are partially independent regarding their protein stability,

132 In particular, we found that partially independent variation in stomatal and mesophyl

133 at U. botrytis MAT genes have the ability to partially induce sexual reproduction in C. heterostrophu

134 stitution at position 405 (D405N) mutant was partially inhibited by a proton concentration of 10(-5.5

135 While BIN1 colocalized with and partially inhibited DNM2 activity during muscle maturati

136 w endocytosis and rapid endocytosis but only partially inhibited excess endocytosis following intense

137 Atpenin A5 partially inhibits oxygen consumption, and neither hypox

138 The strategy is based on a three-fold, partially intermolecular [2+2+n] (n = 1 or 2) cycloaddit

139 ere thrombocytopenia) or that were addressed partially (invasive procedures), the ASCO search extende

140 s, we extend the LCT to a new structure, the partially labeled coalescent tree (PLCT) and demonstrate

141 incorporating, for example, the influence of partially linked deleterious mutations and the maintenan

142 d anti-inflammatory signature in astrocytes, partially linked to the STAT3 network.

143 an acidic pH-activated lysosomal transporter partially localized to mitochondria.

144 pigenetic remodeling and are transiently and partially localized to the nucleus.

145 n levels and hence oxidative metabolism were partially maintained in microRNA-146a knockout mice.

146 ated by a positively charged surface that is partially masked by its intramolecular interaction with

147 eir photospheres are obscured by dust, which partially masks the convective patterns.

148 ortical and subcortical regions was found to partially mediate the relation between adverse life even

149 tion is orchestrated by active-site sterics, partially mediated by an unusual heme-polypeptide ester

150 These effects were partially mediated by CD44-expressing EVs.

151 rsion status were found to do so in a manner partially mediated by rate of cortical thinning (point e

152 ion against asthma by farm-milk exposure was partially mediated by regulatory T cells (Tregs).

153 on, also reduced dwell time on threat, which partially mediated clinical effects.

154 Patient expectations postrandomization partially mediated group effects on week 8 HAM-D.

155 on analysis, lower cow milk consumption only partially mediated the association between noncow milk c

156 urden and anxiety during HCT hospitalization partially mediated the effect of the intervention on dep

157 whereas grey matter (GM) in auditory cortex partially mediates auditory delay, suggesting less effic

158 r (WM) microstructure in the optic radiation partially mediates visual delay, suggesting increased tr

159 conformation and the preceding alpha6 helix partially melted.

160 nt and migrant males, females and pairs in a partially migratory bird.

161 This effect can be partially mimicked by stimulation of Hmox1(+/+) SCs with

162 -BNI injections, and BNST U50,488 injections partially mimicked the drug's systemic effect on reinsta

163 related to an increase in moisture which is partially mitigated by weakening circulation.

164 ROS levels, rescues HSC cycling defects, and partially mitigates HSPC DNA damage.

165 reducing environment in the intestine and to partially modulate glucose metabolism.

166 The associations were only partially modulated by the unhealthy lifestyle habits of

167 s of active Rac1 at epithelial junctions are partially modulated via interaction with Ajuba, an actin

168 However, B cell activation was only partially normalized post-ART, with the frequency of act

169 Characterization of novel transcripts into partially novel transcripts (PNTs) and completely novel

170 f-reported HIV status into analyses based on partially observed HIV serological values.

171 The Partially-Observed Boolean Dynamical System (POBDS) sign

172 We introduce the R package BoolFilter for Partially-Observed Boolean Dynamical Systems (POBDS).

173 in which the C-terminal cysteine-rich domain partially occludes the enzyme active site, preventing un

174 The structure revealed that ciA-C2 partially occupies the SV2-binding site on HCA1, causing

175 rly robust over California, where it is only partially offset by projected decreases in low-medium in

176 nd does not covary with levels of income-can partially offset the effects of low income on myopic dec

177 neurotransmission can be segregated at least partially on a molecular level.SIGNIFICANCE STATEMENT Ac

178 tinct pattern of oral shedding which depends partially on the age and immune status of the host.

179 simple method to characterize both fully and partially ordered regions in the bound state of IDPs.

180 We show that the NTD is partially ordered when it is natively attached to the Tu

181 Importantly, ABS1 and ABS3 partially overlap on the surface of actin and, therefore

182 t binds to GPCRs with interactions that only partially overlap with previously described CTS, indicat

183 NS9283, indicating that their binding sites partially overlap.

184 nel guides RNA to either Rrp6 or Rrp44 using partially overlapping and mutually exclusive paths, seve

185 e pit, papilla, and knob type are labeled by partially overlapping but different subsets of GAL4 driv

186 ulations we further show that K-Ras uses two partially overlapping interfaces to form compositionally

187 d sample consists of a large amount of BNNSs partially overlapping one another with random orientatio

188 ating a limited expression consistency among partially overlapping stresses.

189 r find that effects of Tel1 are distinct but partially overlapping with previously described contribu

190 egion and, when a mRNA structure overlaps or partially overlaps with the ribosomal footprint, the fre

191 0) in the active catalyst core together with partially oxidized Cu species was unraveled.

192 advantage of the NR selectivity, we treated partially oxidized graphene sheets (po-Gr) with NR to ob

193 omatics, resins, and asphaltenes (SARA), was partially oxidized, resulting in a decline in saturates

194 Genetic deficiency in mice resulted in a partially penetrant embryonic or perinatal lethal phenot

195 Thus, MYXV is fully or partially permissive for the majority of human cancer ce

196 Here we find that YTHDF2 deficiency is partially permissive in mice and results in female-speci

197 Thus LPS stimulated monocytes are partially permissive lytic gene expression but did not h

198 ng Cntn5 from either ooDSGCs or interneurons partially phenocopies Satb1 mutants, demonstrating that

199 ng as a result of internal elasticity of the partially polymerized semisolid drops.

200 While ATP binding was sufficient to partially populate the OF state, nucleotide trapping in

201 thionine, which coordinates F(-) through its partially positive gamma-methylene in mimicry of phenyla

202 ropospheric temperatures, the ice surface is partially premelted.

203 nn model (DBM) for premixed, nonpremixed, or partially premixed nonequilibrium reactive flows.

204 Cu@Gr was found to partially prevent the formation of WC after sintering, a

205 onoyl-fluorophosphate and palmostatin B, and partially prevented by JZL184 and WWL113.

206 iated killing of human beta-cells, a process partially prevented by MCL-1 overexpression.

207 in compaction in preimplantation embryos can partially proceed in the absence of zygotic transcriptio

208 ysis is readily available for HGT and may be partially protected from the environment, describe the e

209 ith the small molecule TNFR inhibitor R-7050 partially protected hyperoxaluric mice from nephrocalcin

210 pletion of inflammatory monocyte macrophages partially protected these mice from lethal SARS.

211 RV144 induced antibodies to HIV that were partially protective against infection, as well as antib

212 Explaining why DLK inhibition is only partially protective, we identify leucine zipper kinase

213 losum and internal capsule on day 3 and then partially recovered over time.

214 s are available which completely or at least partially reduce the number or duration of attacks.

215 osiglitazone or hypertension with lisinopril partially reduced ACR, consistent with independent contr

216 rs of endothelial cell activation, which was partially reduced by genetic complement inhibition.

217 e propose that OsbHLH068 and AtbHLH112 share partially redundant functions in the regulation of abiot

218 phic chondrocytes and perform essential, but partially redundant roles in growth plate maturation.

219 ction, Il10 expression in CD4(+) T cells was partially regulated by both IL-27 and type I IFN signali

220 Some gene expression changes were partially relieved in Ki-67-depleted hTERT-RPE1 cells by

221 of non-MSC-associated LysRS is observed and partially relocalized to the nucleus.

222 The ions of a solution can be partially removed under the application of an electric f

223 in the anode catalytic layer of the DMFC is partially replaced by an ionomer with molecular recognit

224 Transcriptional responses partially reproduced in vivo signatures, but these micro

225 n of differentiation markers and presence of partially reprogrammed cells which retained a typical ge

226 survival in phosphate starvation and is only partially required for inducing PHO genes.

227 tion of Runx2 in chondrocytes could at least partially rescue DMM-induced OA-like defects in adult mi

228 cells retrieved from the mated female uterus partially rescue in vitro fertilization (IVF) that faile

229 ects in actin filament organization that are partially rescued by concurrent overexpression of Nedd4.

230 contraction of the fecal microbiome and were partially rescued by fecal microbiota transfer.

231 in synaptic transmission in aged mice can be partially rescued by improving calcium buffering, or dec

232 mTORC1 and IFN-gamma production defects were partially rescued by supplementation with glutamine, whi

233 as in FABP4/aP2 inhibitor-treated cells, but partially rescued in FABP4/aP2-null macrophages when UCP

234 The SA-induced promoter responses could be partially rescued in sdhaf2, but not in dsr1, by supplem

235 ro, and the cAMP analogue 8-bromo-cyclic AMP partially rescued the circadian phenotype in vivo We the

236 a lentivirus encoding the wild-type protein partially rescued the deficiency of GPI-anchored protein

237 Exogenous application of ABA partially rescued these phenotypes, confirming that they

238 miR-277 mimic injection partially rescued these phenotypic manifestations.

239 Importantly, Dkk1 overexpression partially rescues miR31-induced mammary defects.

240 OsMTP11 partially rescues the Mn-hypersensitivity of the pmr1 ye

241 ion-based DNA-repair mechanisms are at least partially responsible for the different evolutionary out

242 We speculate that estrogen replacement might partially restore neurogenesis in human premature infant

243 contrast, GLUT4 protein expression was only partially restored by increased NAD/P levels.

244 ertility of heterochromatin mutants could be partially restored by inhibiting cep-1/p53, endogenous m

245 Moreover, the ICB approach partially restored expression of several derepressed miR

246 pression of E3 ligase-inactive TRAF6 mutants partially restored IL-1 signaling in TRAF6 KO cells, but

247 -/- mice compared with wild types, which was partially restored in Scn2a+/-; Kcna1-/- mice.

248 rbitol application during flower development partially restored MdMYB39L expression, stamen developme

249 erforin expression in CD56(dim) NK cells and partially restored NK cell cytotoxic function.

250 n of sorbitol to the germination medium also partially restored pollen germination and tube growth of

251 Neutralization of HLA-G, TGF-beta, and IL-10 partially restored T cell alloproliferation, arguing for

252 Additionally, calorie restriction partially restored the impaired BAT glucose uptake.

253 ion of human macrophage cells in culture and partially restored the number of kidney MPCs when admini

254 CS disaccharides partially restored total fecal short-chain fatty acids f

255 op objects not seen with the implant OFF was partially restored with the implant ON in all but 1 part

256 infection, blockade of type I IFN signaling partially restores antiviral responses.

257 tenin signaling in CNS vessels during EAE/MS partially restores functional BBB integrity and limits i

258 he proteasome because a proteasome inhibitor partially restores the alpha1 protein level.

259 Importantly, BRCA2 overexpression partially restores the USP21-associated survival defect.

260 suppresses the effects of EGFR inhibition by partially restoring the EGFR-promoted gene expression pr

261 l and functional hotspot of this interaction partially restructured the helical IL-23p19 subunit of I

262 ation, whereby the ancestral F6H activity is partially retained in the derived SbCYP82D2.

263 ue and interesting features, which have been partially revealed through spectroscopic, kinetic, and d

264 Knockdown of phb2 partially reversed beneficial effects of SPL overexpress

265 and inhibition of the IFN-alpha response was partially reversed by a deficiency in the T. gondii-deri

266 These downstream effects were partially reversed by antibodies against the RvD1 recept

267 toward a TH1-like cell phenotype, which was partially reversed by CTLA4-Ig therapy.

268 This phenotype was partially reversed by ER-beta-selective ligand.

269 ro-apoptotic genes in tumor cells, which was partially reversed by overexpression of PcG member BMI-1

270 primary human eSCs can be prevented and even partially reversed ex vivo by peroxisome proliferator-ac

271 ux in response to hyperammonemia, which were partially reversed following 24-hour and 48-hour withdra

272 PD-1 inhibitory receptor blockade partially reversed T cell unresponsiveness.

273 growth and tumor formation, and ectopic MYCN partially reversed the effects of MDM2 depletion, indica

274 ver, progesterone receptor antagonist RU-486 partially reversed the effects of P4 on NF-kappaB pathwa

275 y reversible, (ii) fully irreversible, (iii) partially reversible transitions, and (iv) general three

276 ckdown phenotype, which are thus shown to be partially secondary to pathogen-induced inflammation.

277 biochemically and structurally, and the one partially sharing some of the GSS PrP(Sc) molecular feat

278 e leg primordia are absent, the DP are still partially specified.

279 Lumacaftor partially stabilized purified full-length F508del-CFTR a

280 ch converts diacylglycerol to phosphatidate, partially suppressed the pah1Delta-mediated induction of

281 earing the sonar emissions of the nearby bat partially suppressed this response.

282 tm sp double mutants, and late flowering was partially suppressed, suggesting that LTM functions to s

283 The cluster is surprisingly only partially surrounded by the endoplasmic reticulum, a key

284 Partially switched domains, which enable the formation o

285 The topological structure determines partially the hierarchical arrangement of roads, but sin

286 riptional target of BCL6 in GBM and mediates partially the regulatory effects of BCL6 on both MEK-ERK

287 lation of U2AF65 could account for, at least partially, their co-regulated alternative splicing event

288 as structures of uncleaved, unthreaded, and partially threaded 5' flaps.

289 revealed that EIN2-C associates with histone partially through an interaction with EIN2 nuclear-assoc

290 This was mediated at least partially through upregulation of the cell cycle inhibit

291 th to nanobeams in which the LOS ranges from partially to entirely blocked by introducing slits, s =

292 load (GL) value determinations has remained partially unaddressed.The study aimed to determine the e

293 ature and extent of such cross talk are only partially understood at present.

294 dynamics of the replication fork remain only partially understood, preventing a molecular understandi

295 nditions and in disease states, remains only partially understood.

296 med death 1 (PD-1) and its ligand (PD-L1) is partially understood.

297 Populating transient and partially unfolded species is a crucial step in the form

298 The partially unfolded species possess an unstructured beta-

299 ting the equilibrium away from the extended, partially unfolded state towards a compact, pre-organize

300 anti-TcdB antibody bezlotoxumab, which binds partially within the first three short repeats, prevents