ライフサイエンスコーパス: parvovirus

1 erminal domain, the first for any autonomous parvovirus.

2 irus B19 (B19V) is the only human pathogenic parvovirus.

3 n profile that was similar to that of bovine parvovirus.

4 extensive similarities with those of bovine parvovirus.

5 e evolution and the biology of this emerging parvovirus.

6 s annotations within NCBI databases, such as parvovirus.

7 ggests implications for replication of other parvoviruses.

8 ine tumor cell tropism for oncotropic rodent parvoviruses.

9 elded BLASTx E scores of 7e-05-0.008 against parvoviruses.

10 <31% identities to those of previously known parvoviruses.

11 oted after other infections, for example, by parvoviruses.

12 plant, and animal viruses, as well as other parvoviruses.

13 (GmDNV) but in stark contrast to vertebrate parvoviruses.

14 in many icosahedral viruses, including other parvoviruses.

15 n the fivefold channel as observed for other parvoviruses.

16 ng strategy of the B19 virus is unique among parvoviruses.

17 nd splicing was different from that of other parvoviruses.

18 first noncoding RNA identified in autonomous parvoviruses.

19 (HBoV) and PARV4 are newly discovered human parvoviruses.

20 ace topologies different from those of other parvoviruses.

21 d divergence of AAVR engagement within these parvoviruses.

22 Muscovy duck- or other duck species-related parvoviruses.

23 wo dominant epitopes reported for autonomous parvoviruses.

24 stic dog TfR that dictates susceptibility to parvoviruses.

25 vovirus (CPV), porcine parvovirus (PPV), rat parvovirus 1A (RPV1A), and H-3 were relatively ineffecti

26 ated virus, bovine influenza D virus, bovine parvovirus 2, bovine herpesvirus 6, bovine rhinitis A vi

27 Parvovirus 4 (PARV4) is a DNA virus frequently associate

28 on X-ray crystal structure of mature cricket parvovirus (Acheta domesticus densovirus [AdDNV]) has be

29 The parvovirus adeno-associated virus (AAV) contains a small

30 The life cycle of the human parvovirus adeno-associated virus (AAV) is orchestrated

31 embers, potently inhibits replication of the parvovirus adeno-associated virus (AAV).

32 The use of vectors based on the small parvovirus adeno-associated virus has gained significant

33 anscription profile of Aleutian mink disease parvovirus (AMDV)-infected CRFK cells at either 32 degre

34 APOBEC3 proteins restrict herpesviruses and parvoviruses, among others, but whether they also work i

35 ty that strongly suggests that, in the genus Parvovirus, an active inboard OriL is lethal.

36 ly suggests that bidnaviruses evolved from a parvovirus ancestor from which they inherit a jelly-roll

37 on the basis of genomic similarity to bovine parvovirus and canine minute virus.

38 it is a surprising hybrid of features of the Parvovirus and Dependovirus genera of the Parvovirinae s

39 o human and animal parvoviruses (PVs) in the Parvovirus and Dependovirus genera within genomes of sev

40 isons at the strain (HBoV) and genus (bovine parvovirus and HBoV) levels identified differences in su

41 -1PV nucleotides to those observed in canine parvovirus and minute virus of mice, two members of the

42 EnPVs, one genetically more similar to genus Parvovirus and the other genetically more similar to the

43 ndescribed DNA viruses were also detected, a parvovirus and two viruses related to TT virus (TTV).

44 d two genera in the family Parvoviridae, the parvoviruses and dependoviruses, were found and were bro

45 sm, pathogenicity, and antigenicity in other parvoviruses and likely play similar roles in these viru

46 ve been characterized that bind to different parvoviruses and mediate their entry into cells.

47 vovirus distinct from known human and animal parvoviruses and of two related TTV-like viruses highly

48 Here, we examine the properties of parvoviruses and their interactions with their hosts tha

49 herpes simplex virus, norovirus, rotavirus, parvovirus, and Epstein-Barr virus.

50 Enterovirus, kobuvirus, parechovirus, parvovirus, and rotavirus sequences were frequently dete

51 d perhaps of other A3s against retroviruses, parvoviruses, and hepatitis B virus.

52 ere used as a model system to detect porcine parvovirus antibody in swine sera via flow cytometry, an

53 acid sequence alone, the antigenic sites of parvoviruses appear to be dictated by structural feature

54 Members of the genus Parvovirus are small, nonenveloped single-stranded DNA v

55 Although parvoviruses are commonly described in domestic carnivor

56 Parvoviruses are commonly found in both vertebrate and i

57 om animals has shown just how widespread the parvoviruses are in nature, but most of the newly discov

58 Parvoviruses are single-stranded DNA viruses that use th

59 Parvoviruses are small, rugged, nonenveloped protein par

60 Then, using porcine parvovirus as an example, we use these parameters to inv

61 nuclear replication compartments (autonomous parvovirus-associated replication [APAR] bodies) during

62 against human glioblastomas, we screened 12 parvoviruses at a high multiplicity of infection (MOI).

63 We analyzed the response to parvovirus B19 (B19), a ubiquitous and clinically signif

64 ive Finnish casualties from World War II for parvovirus B19 (B19V) DNA, and found a remarkable preval

65 The pathogenic parvovirus B19 (B19V) has an extreme tropism for human e

66 Intrauterine parvovirus B19 (B19V) infection can be asymptomatic or m

67 Human parvovirus B19 (B19V) infection has a unique tropism to

68 Parvovirus B19 (B19V) infection is highly restricted to

69 Human parvovirus B19 (B19V) infection is restricted to erythro

70 Accurate diagnosis of parvovirus B19 (B19V) infection requires the differentia

71 Human parvovirus B19 (B19V) infection shows a strong erythroid

72 Human parvovirus B19 (B19V) is a common pathogen in microvascu

73 Parvovirus B19 (B19V) is a member of the family Parvovir

74 Human parvovirus B19 (B19V) is a member of the genus Erythrovi

75 Parvovirus B19 (B19V) is pathogenic for humans and has a

76 Human parvovirus B19 (B19V) is the only human pathogenic parvo

77 ng of the precursor mRNA (pre-mRNA) of human parvovirus B19 (B19V) plays a key role in posttranscript

78 Alternative processing of parvovirus B19 (B19V) pre-mRNA is critical to generating

79 knowledge of the crystal structure of human parvovirus B19 (genus Erythrovirus).

80 ure red cell aplasia (PRCA) related to human parvovirus B19 (HPV-B19) infection.

81 The structures of infectious human parvovirus B19 and empty wild-type particles were determ

82 recent studies investigating the presence of parvovirus B19 and herpesviruses in temporal arteries wi

83 regnant Ghanaian women were tested for human parvovirus B19 DNA and B19-specific antibodies.

84 Parvovirus B19 has been implicated in some cases of acut

85 Parvovirus B19 immunoglobulin M positivity was associate

86 irst-trimester serum samples were tested for parvovirus B19 immunoglobulin M positivity.

87 her examine the role of the host response to parvovirus B19 in the development of symptoms and conseq

88 Because parvovirus B19 infection during pregnancy has been assoc

89 In conclusion, acute parvovirus B19 infection during the first trimester of p

90 Parvovirus B19 infection in adults is often associated w

91 n HLA-A*2402-positive individuals with acute parvovirus B19 infections made vigorous CD8-positive cyt

92 ly 0.1% of fetal losses were attributable to parvovirus B19 positivity, a proportion which could incr

93 capsids, or virus-like particles (VLPs), of parvovirus B19 that carry dengue 2-specific epitopes wer

94 ns (such as syphillis, varicella-zoster, and parvovirus B19), cytomegalovirus, and herpes simplex vir

95 ere detected in EMBs from 37 (39%) patients; parvovirus B19, adenovirus, and Epstein-Barr virus (EBV)

96 hat of Aleutian mink disease virus and human parvovirus B19, autonomous members of the genus, despite

97 oinfection with HBV, and 1 case each of HBV, parvovirus B19, cytomegalovirus, and human herpesvirus 7

98 gene polymorphisms have been associated with parvovirus B19, hepatitis C virus, HIV-1/AIDS infection,

99 Like human parvovirus B19, this virus has a predilection for erythr

100 Infections with human parvoviruses B19 and recently discovered human bocavirus

101 Parvovirus B19V infection can be a serious infection for

102 diversity between the different genera, most parvoviruses bind to negatively charged glycans, such as

103 Bovine parvovirus (BPV), identified in the 1960s in diarrheic c

104 Bovine parvovirus (BPV), the causative agent of respiratory and

105 of mice (MVM), a single-stranded DNA (ssDNA) parvovirus, but not hepatitis B virus.

106 n receptor, the cellular receptor for canine parvovirus, can bind to only one or a few of the 60 icos

107 The nonenveloped parvovirus capsid carries determinants of host and tissu

108 During cellular entry and infection, the parvovirus capsid follows a complex path from the cell s

109 tion 300 is the most variable residue in the parvovirus capsid in nature, suggesting that it is a cri

110 ere are common structural features among all parvovirus capsid proteins.

111 little structural resemblance to other known parvovirus capsid proteins.

112 psids, highlighting the importance of common parvovirus capsid regions in the control of virus-host i

113 Based on the comparison to other existing parvovirus capsid structures, this study suggests capsid

114 e examined the protein composition of canine parvovirus capsids and evaluated their structural variat

115 Parvovirus capsids are assembled from multiple forms of

116 ification that some heterologously expressed parvovirus capsids are indistinguishable from wt capsids

117 Parvovirus capsids are small but complex molecular machi

118 ity determinants mapped for other autonomous parvovirus capsids, highlighting the importance of commo

119 ils that explain cell infection processes of parvovirus capsids.

120 Parvoviruses cause a variety of mild to severe symptoms

121 Human bocavirus 1 (HBoV1), a human parvovirus, causes lower respiratory tract infections in

122 CPV, but not the related feline parvovirus, could use receptors containing a canine TfR-

123 Canine parvovirus (CPV) and feline panleukopenia virus (FPV) ar

124 nfection processes and host ranges of canine parvovirus (CPV) and feline panleukopenia virus (FPV) ar

125 The structures of canine parvovirus (CPV) and feline parvovirus (FPV) complexed w

126 Canine parvovirus (CPV) and its relative feline panleukopenia v

127 the emergence and pandemic spread of canine parvovirus (CPV) are well documented, the carnivore host

128 y visualize the association of single canine parvovirus (CPV) capsids with cellular transferrin recep

129 Canine parvovirus (CPV) emerged in the late 1970s as a host-ran

130 e capsid substitutions that eliminate canine parvovirus (CPV) infectivity and identify how those muta

131 Canine parvovirus (CPV) is a highly contagious pathogen that ca

132 ng natural infections of animals with canine parvovirus (CPV) or its ancestor, feline panleukopenia v

133 Canine parvovirus (CPV) outbreaks can have a devastating effect

134 We studied the binding kinetics of canine parvovirus (CPV) variants isolated from raccoons-a newly

135 s important hosts in the evolution of canine parvovirus (CPV), a pandemic pathogen of domestic dogs.

136 , MVMc, MVM-G17, tumor virus X (TVX), canine parvovirus (CPV), porcine parvovirus (PPV), rat parvovir

137 e panleukopenia virus ("FPV-like") or canine parvovirus ("CPV-like").

138 e first study to report the highly conserved parvovirus DE loop at the 5-fold axis as a determinant o

139 However, unlike other parvoviruses, densities extending the 5-fold channel int

140 FN-beta in glia; in contrast, LuIII and MVMp parvoviruses did not evoke a detectable IFN-beta or inte

141 tic analysis confirmed the presence of a new parvovirus distinct from known human and animal parvovir

142 ides the first evidence of the DDR-dependent parvovirus DNA replication that occurs in dividing cells

143 ggesting novel characteristics of autonomous parvovirus DNA replication.

144 Surprisingly, we found that these parvoviruses do not evoke an interferon response in norm

145 ntact was associated with exposure to canine parvovirus, Ehrlichia canis, Neospora caninum and perhap

146 Parvoviruses encode a large nonstructural protein 1 (NS1

147 r, phylogenetic analysis of these endogenous parvovirus (EnPV) sequences demonstrated substantial gen

148 The single-stranded DNA (ssDNA) parvoviruses enter host cells through receptor-mediated

149 To identify the parvovirus(es) with the optimal oncolytic effect against

150 irpins are highly conserved within the genus Parvovirus, exemplified by the 121-nucleotide left-end s

151 one using all known representative exogenous parvovirus (ExPV) and EnPV sequences showed two major ge

152 ndogenous viral elements (EVEs) derived from parvoviruses (family Parvoviridae) in the genomes of the

153 The BPV capsid displays common parvovirus features: a channel at and depressions surrou

154 ctures of canine parvovirus (CPV) and feline parvovirus (FPV) complexed with antibody fragments from

155 ison of the HBoV capsid structure to that of parvoviruses from five separate genera demonstrates stro

156 ofold-related neighbor similar to the insect parvovirus Galleria mellonella densovirus (GmDNV) but in

157 The Bocavirus bovine parvovirus generated a single pre-mRNA from a promoter a

158 ly triggered by integration of the ancestral parvovirus genome into a large virus-derived DNA transpo

159 inute virus of mice and other members of the Parvovirus genus, a significant portion of pre-mRNAs gen

160 Also similar to members of the Parvovirus genus, detectable activity of the GPV P42 pro

161 ts characterization reveals another way that parvoviruses govern access to their capsid protein genes

162 arvovirus with a greater similarity to goose parvovirus (GPV) (97% protein homology) than to Muscovy

163 The goose parvovirus (GPV) Rep 1 and Rep 2 proteins are encoded by

164 The RNA transcription profile of the goose parvovirus (GPV) was determined, and it is a surprising

165 losely clustered with two known goose-origin parvoviruses (GPVa2006 and GPV1995), together forming a

166 The parvoviruses H-1, LuIII, and MVM target cancer cells; ho

167 of single-stranded DNA (ssDNA) packaging H-1 parvovirus (H-1PV), which is being developed as an antit

168 on the virion, indicating that either canine parvovirus has inherent asymmetry or binding of receptor

169 Because the innate immune response to parvoviruses has received relatively little attention, w

170 Parvoviruses have a roughly cylindrically shaped pore th

171 However, variants of some parvoviruses have altered their host ranges to create ne

172 risons show that vertebrate and invertebrate parvoviruses have evolved independently, although there

173 Although parvoviruses have only subtle early-to-late expression s

174 MPORTANCE We first report that an autonomous parvovirus, HBoV1, helps the replication of a dependopar

175 Unlike infections with other parvoviruses, HBoV1 infection did not activate the apopt

176 tructural protein (Rep78/68 or NS1) of other parvoviruses, HBoV1 NS1 did not specifically bind OriR i

177 ted in the control of other viruses, such as parvoviruses, herpesviruses, papillomaviruses, hepatitis

178 Listeria monocytogenes, Treponema pallidium, parvovirus, HIV, varicella zoster virus, Rubella, Cytome

179 The parvovirus human bocavirus 1 (HBoV1) is an emerging resp

180 s, Salmonella spp., E. coli O157 and porcine parvovirus in bioreduction vessels containing sheep carc

181 andemic human influenza A viruses and canine parvovirus in dogs.

182 inute virus of canine (MVC) is an autonomous parvovirus in the genus Bocaparvovirus It has a single p

183 nute virus of canines (MVC) is an autonomous parvovirus in the genus Bocaparvovirus.

184 cells plays a role in the oncoselectivity of parvoviruses in human cells.

185 first evidence for widespread circulation of parvoviruses in primates and enables future investigatio

186 The VP structure differs from those of other parvoviruses in surface loop regions that control recept

187 fecal samples were PCR positive for this new parvovirus, including a related bufavirus species showin

188 of these related genomes from those of other parvoviruses indicates the presence of a proposed new Pa

189 Infection with vaccinia virus or H-1 parvovirus induced less stimulation of the innate immune

190 Parvoviruses infect a wide variety of hosts, and their a

191 us of the capsid viral protein VP1 (VP1u) in parvovirus infection has been reported.

192 The details of parvovirus infection of cells are still not fully unders

193 patients due to hypereosinophilic syndrome, parvovirus infection, aspiration pneumonia, and severe d

194 been discovered about ATM activation during parvovirus infection, involvement of the ATR pathway has

195 emes that have been shown to be important in parvovirus infections.

196 ike most other types of virus, we found that parvovirus infectivity is unaffected by interferon treat

197 by NS1 acting in concert with a host factor, parvovirus initiation factor (PIF).

198 The canine adaptation of the parvoviruses involved capsid protein changes altering th

199 rst to support the notion that an autonomous parvovirus is able to hijack the host DNA damage machine

200 The asymmetry of receptor binding to canine parvovirus is reminiscent of the special portal in taile

201 Parvovirus is the most common viral cause of diarrhea in

202 e left-end promoter of Aleutian mink disease parvovirus is tricistronic; it not only expresses the ca

203 leads to the replication of the DNA of other parvoviruses is facilitated by the cell cycle, the DDR t

204 The diversity of parvoviruses is therefore extensive, and although they a

205 ocalize with PML, PML's functional effect on parvoviruses is unknown.

206 o-associated virus (AAV) serotype 9, a human parvovirus isolate.

207 proximately 25% of animals infected with the parvovirus Kilham rat virus (KRV) develop autoimmune dia

208 The virus, provisionally named parvovirus-like hybrid virus (PHV), is nearly identical

209 s, like those of B19, self-assembled to form parvovirus-like particles, and these capsids, like B19 c

210 V in human disease, our data indicate that a parvovirus-like virus is highly prevalent in a cohort of

211 ts and representatives of a clearly distinct parvovirus lineage that also has endogenous representati

212 The interferon-resistant phenotype of parvoviruses may give them an advantage over interferon-

213 s enhanced by oncogenic transformation, some parvoviruses may have potential utility in killing cance

214 (97% protein homology) than to Muscovy duck parvovirus (MDPV) (90% protein homology).

215 antigenic hotspots on AAVs and other related parvoviruses might be evolutionarily conserved.

216 MVM infection.IMPORTANCE Replication of the parvovirus minute virus of mice (MVM) induces a sustaine

217 The parvovirus minute virus of mice (MVM) packages a single

218 The parvovirus minute virus of mice (MVM) packages predomina

219 Two strains of the parvovirus minute virus of mice (MVM), the immunosuppres

220 s) during replication of the single-stranded parvovirus minute virus of mice (MVM).

221 ectious cell surface receptor recognition by parvovirus minute virus of mice (MVM).

222 ex virus 1 and murine herpesvirus 68 and the parvovirus minute virus of mice (MVM).

223 a structural rearrangement that can occur in parvovirus minute virus of mice (MVMp) virions following

224 Human influenza viruses and Parvovirus Minute Viruses of Mice also specifically reco

225 Although dependovirus (AAV) and autonomous parvovirus (minute virus of mice) replication centers ca

226 Upon infection, the parvovirus MVM activates a cellular DNA damage response

227 estingly, we found that IFN did not decrease parvovirus (MVMp, LuIII, and H-1) infectivity in normal

228 Concurrent infections with either parvovirus (n = 1), attaching-effacing Escherichia coli

229 Substitution of the canine parvovirus NLS rescued the BR3 mutant to wild-type (wt)

230 and sequence the full VP2 gene of 150 canine parvoviruses obtained from a large cross-sectional sampl

231 In contrast with other parvoviruses, only expression of the MVC proteins by tra

232 Incubation of mammalian cells with porcine parvovirus PLA(2) led to the release of arachidonic acid

233 us X (TVX), canine parvovirus (CPV), porcine parvovirus (PPV), rat parvovirus 1A (RPV1A), and H-3 wer

234 NP1 is the first parvovirus protein implicated in RNA processing.

235 en fully elucidated, it represents the first parvovirus protein to be implicated directly in viral RN

236 We show here that MVC NP1, the first parvovirus protein to be implicated in RNA processing, g

237 Sequences from a highly divergent parvovirus, provisionally called bufavirus, were also de

238 In contrast to other parvoviruses, PstDNV probably has only one type of capsi

239 everal sequences related to human and animal parvoviruses (PVs) in the Parvovirus and Dependovirus ge

240 ing that GPV-QH15 evolved from goose lineage parvoviruses, rather than from Muscovy duck- or other du

241 investigate the exposure and circulation of parvoviruses related to B19 virus, PARV4, and HBoV in no

242 The mechanism of parvovirus replication has been studied mostly in the de

243 Because productive infection by parvoviruses requires cell division and is enhanced by o

244 circovirus and the capsid protein of porcine parvovirus, respectively.

245 nonstructural and capsid proteins of canine parvovirus, respectively.

246 2.1% with that of human bocavirus and bovine parvovirus, respectively.

247 -associated virus (AAV) is a single-stranded parvovirus retaining the unique capacity for site-specif

248 hese pipelines were implemented and detected parvovirus sequence in the sample that the ECBC iterativ

249 nute virus of mice, two members of the genus Parvovirus, showed both similarity in structure and anal

250 sed to identify a previously uncharacterized parvovirus species, "HBoV2," whose closest phylogenetic

251 Simian parvovirus (SPV) causes severe anemia in immunocompromis

252 Simian parvovirus (SPV) was first isolated from cynomolgus monk

253 d the alphaA helix, which are present in all parvovirus structures.

254 lements, which also exist in all other known parvovirus structures.

255 tropisms, have features in common with other parvoviruses, such as depressions at the icosahedral 2-f

256 Autonomous parvoviruses, such as minute virus of mice and B19, whil

257 , similar to findings for other invertebrate parvoviruses, suggesting domain swapping is an evolution

258 ation, which are processes necessary for all parvoviruses, suggests implications for replication of o

259 repare the nuclear environment for effective parvovirus takeover.

260 A new species of parvovirus, tentatively named human bocavirus 4 (HBoV4),

261 Human bocavirus 1 (HBoV1) is a human parvovirus that causes acute respiratory tract infection

262 bocavirus 1 (HBoV1) is a single-stranded DNA parvovirus that causes lower respiratory tract infection

263 H15 represents a new variant of goose-origin parvovirus that currently circulates in ducklings and ca

264 sociated virus serotype 5 (AAV-5) is a human parvovirus that infects a high percentage of the populat

265 Human bocavirus 1 (HBoV1) is an autonomous parvovirus that infects well-differentiated primary huma

266 s is a newly identified, globally prevalent, parvovirus that is associated with respiratory infection

267 iated virus (AAV) is a replication-deficient parvovirus that is extensively used as a gene therapy ve

268 Adeno-associated virus (AAV) is a human parvovirus that normally requires a helper virus such as

269 nute virus of canines (MVC) is an autonomous parvovirus that replicates efficiently without helper vi

270 no-associated virus (AAV) is a nonpathogenic parvovirus that requires adenovirus (Ad) or another help

271 bocavirus (HBoV) is a newly identified human parvovirus that was originally identified in the respira

272 anleukopenia virus (FPV) are closely related parvoviruses that differ in their host ranges for cats a

273 The full extent of the genetic diversity of parvoviruses that have undergone endogenization during e

274 In contrast to vertebrate parvoviruses, the N-terminal beta-strand of BmDNV-1 VP3

275 Similar to studies with autonomous parvoviruses, this study describes the first example of

276 ocyte leukemia; infections, particularly B19 parvovirus; thymoma and other solid tumors; or a variety

277 ited the unique life cycle of the autonomous parvoviruses to develop a nonproliferating vaccine platf

278 ittle attention, we compared the response to parvoviruses to that of several other types of viruses i

279 Canine parvovirus type 2 (CPV-2) emerged as a variant of a feli

280 Canine parvovirus type 2 (CPV-2) emerged in 1978 and spread wor

281 Canine parvovirus type 2 (CPV-2) is a severe enteric pathogen o

282 a partial VP2 sequence of 54 samples, canine parvovirus type 2c (CPV-2c) (n = 26), CPV-2b (n = 25), a

283 Parvoviruses use a variety of means to control the expre

284 's effect on adeno-associated virus (AAV), a parvovirus used for gene delivery.

285 fection associated with enteritis as well as parvovirus viremia in animals with advanced AIDS, indica

286 Progeny production of parvoviruses was also unimpaired by IFN in both glioma a

287 The radiation of bidnaviruses from parvoviruses was probably triggered by integration of th

288 Human bocavirus (HBoV), a parvovirus, was discovered in 2005 with the use of nonsp

289 ive amino acid variation among the carnivore parvoviruses, we further investigated its role in determ

290 nversely, higher read numbers from different parvoviruses were associated with healthy animals.

291 Two human parvoviruses were recently discovered by metagenomics in

292 e 2 (CPV-2) emerged as a variant of a feline parvovirus when it acquired mutations that allowed bindi

293 AV) is a nonpathogenic single-stranded human parvovirus which usually requires the presence of a "hel

294 de up 1 to 3% of the viral reads, except for parvoviruses, which made up 23% of the viral reads in th

295 HBoV1 is the first parvovirus whose NS1 has been shown to be able to activa

296 the tropism and pathogenicity of these novel parvoviruses will be facilitated by the availability of

297 and virological studies, which identified a parvovirus with a greater similarity to goose parvovirus

298 Adeno-associated virus (AAV) is a parvovirus with a small single-stranded DNA genome that

299 sm of LuIII's phenotype, we used recombinant parvoviruses with the LuIII capsid replacing the MVMp ca

300 most closely related to members of the genus Parvovirus, with >70% and 65% amino acid identities to n