ライフサイエンスコーパス: pathogen

1 les virus (MeV) has regained importance as a pathogen.

2 closin, is crucial for the viability of this pathogen.

3 zobacteria that can also act as a mild phyto-pathogen.

4 be applied to the conjugates of this lethal pathogen.

5 s pneumoniae (pneumococcus) is a major human pathogen.

6 her than the direct activity of any specific pathogen.

7 in a generalist but not a specialist fungal pathogen.

8 uding coinfections by recognized respiratory pathogens.

9 in the homolog of other Helicobacter gastric pathogens.

10 al first line of defense against respiratory pathogens.

11 of vaccine strategies against fast mutating pathogens.

12 itment as each phagocyte eliminated numerous pathogens.

13 he modulation of host defences against viral pathogens.

14 intracellular survival of multiple bacterial pathogens.

15 ergy by several bacteria including important pathogens.

16 of interferon-inducible GTPases to vacuolar pathogens.

17 f rapidly clearing causative and coinfecting pathogens.

18 lso promote infection with macrophage-tropic pathogens.

19 dissemination of highly antibiotic-resistant pathogens.

20 y that restrict replication of intracellular pathogens.

21 susceptible to infection with oral bacterial pathogens.

22 d susceptibility to ubiquitous opportunistic pathogens.

23 nt strategy for innate immune recognition of pathogens.

24 ectious Disease-assigned category A priority pathogens.

25 lthough it is key in the clearance of fungal pathogens.

26 d by this most intractable of drug resistant pathogens.

27 roles in innate immune responses to invading pathogens.

28 ular particles including apoptotic cells and pathogens.

29 nimals and plants as natural defense against pathogens.

30 ins secreted by many Gram-positive bacterial pathogens.

31 articipates in defense against intracellular pathogens.

32 l design to macrolide-binding TetRs found in pathogens.

33 nd facilitates colonization by opportunistic pathogens.

34 tion and suppress the emergence of resistant pathogens.

35 facing high minimal inhibitory concentration pathogens.

36 t bay and defending against invading enteric pathogens.

37 live-cell imaging probe for different fungal pathogens.

38 lly hazardous constituents and opportunistic pathogens.

39 capable of protecting natural aquafers from pathogens.

40 nd control the spread of hospital-associated pathogens.

41 od, raw flour can be a vehicle for foodborne pathogens.

42 tem and define first-line of defence against pathogens.

43 s (SNFs), and at various risks for resistant pathogens.

44 susceptibility to infection by opportunistic pathogens.

45 Pathogen-activated Toll-like receptors (TLRs), such as T

46 Notably, phagocytosis of the pathogen activates the host autophagy initiation complex

47 disease, but to be certain that a candidate pathogen actually causes disease, it is necessary to pro

48 of pathogen-borne diseases and to know which pathogens actually cause fever.

49 nd symbiotic fungi (mutualists and potential pathogens) affect plant survival, physiological traits,

50 her genus containing potential opportunistic pathogens, also occurred ubiquitously.

51 ing equations (GEE) for the global (ie, any) pathogen analyses, with adjustments made for the presenc

52 of informal trade on both the spread of the pathogen and its control using clean-seed systems, deter

53 sed to mount an effective response against a pathogen and yet maintain tolerance toward commensal bac

54 Phi) recognize the molecular constituents of pathogens and activate the host's innate immune response

55 ates CD8(+) T cell-mediated immunity against pathogens and cancers.

56 adaptive T-cell immunity against infectious pathogens and cancers.

57 e tract is the first line of defense against pathogens and damage.

58 important in urban environments for removing pathogens and improving water quality.

59 mary physical airway defense against inhaled pathogens and irritants.

60 ter plays a role in defense against numerous pathogens and is recruited to sites of pathogen detectio

61 garding induced systemic resistance (ISR) to pathogens and pests in whitebark pine.

62 s is believed to undermine immunity to other pathogens and to accelerate immunosenescence.

63 used to protect individuals against several pathogens and toxins.

64 (NEL) domain that is unique to Gram-negative pathogens and whose activity is repressed by a flanking

65 cell-signaling pathways and defense against pathogens and whose imbalance leads to pathological cond

66 rpret BCID results, identify the most likely pathogen, and then choose therapy based on the results.

67 olved in stress response against herbivores, pathogens, and abiotic stress.

68 tion resistance against many orally acquired pathogens, and antibiotic-mediated depletion of the micr

69 ecting against colonization and infection of pathogens, and guiding the host immune system in respons

70 es and metagenomic datasets, including human pathogens, and is considered to be widely distributed in

71 s) mediate optimal protection to respiratory pathogens, and we hypothesized that reduced protection i

72 on, occupation, or immunosuppression; fungal pathogens appearing in geographical areas in which they

73 Microbial pathogens are exposed to damaging reactive oxygen specie

74 Bacterial pathogens are increasingly antibiotic resistant, and dev

75 Bcc pathogens are intrinsically resistant to multiple antibi

76 iple specimens improve sensitivity, multiple pathogens are often detected and this adds complexity to

77 his ubiquitin coating of Shigella favors the pathogen as it liberates bacteria from GBP encapsulation

78 eal flora and higher prevalence of potential pathogens as markers of higher quality, <10 SECs per LPF

79 niche exploited by several highly prevalent pathogens as well as by primary and metastatic tumors.

80 ar neutrophils (PMN) to bacterial and fungal pathogens as well as to model inflammatory stimuli, and

81 These methods revealed that dsRNA, a pathogen-associated molecular pattern (PAMP), comprised

82 the role of post-translational responses to pathogen-associated molecular pattern and damage-associa

83 tiple receptors including insulin receptors, pathogen-associated molecular pattern receptors, cytokin

84 Recognition of pathogen-associated molecular patterns and danger-associ

85 tracellular receptors that recognize various pathogen-associated molecular patterns and play crucial

86 4 (NLRC4)/Ipaf is involved in recognition of pathogen-associated molecular patterns leading to caspas

87 well-orchestrated defense strategies against pathogen attack.

88 s, BB0238 and BB0323, play distinct roles in pathogen biology and infectivity although a significance

89 whooping cough, caused by the obligate human pathogen Bordetella pertussis is undergoing a worldwide

90 eeded to better describe the distribution of pathogen-borne diseases and to know which pathogens actu

91 athogenic E. coli (EPEC), an important human pathogen, both in virulence activating and non-activatin

92 immune and physical barriers protect against pathogens but also impede the establishment of essential

93 orate effector functions upon re-exposure to pathogens, but also have many properties in common with

94 in Zanzibar, are heavily exposed to enteric pathogens, but capable of rapidly clearing causative and

95 Diarrhea is a host response to enteric pathogens, but its impact on pathogenesis remains poorly

96 at beside a role in sugar deprivation of the pathogen by competing for sugar availability in the apop

97 lay an important role in immune responses to pathogens by transducing signals in innate immune cells

98 The foodborne microaerophilic pathogen, Campylobacter jejuni, possesses a periplasmic

99 In such a surface network, pathogen can be transmitted great distances quickly-as f

100 Leukocytes and pathogens can pass directly through the endothelium by o

101 New emerging pathogens can quickly become a global health threat in t

102 ed that protein effectors secreted by fungal pathogens can spread between host cells via PD.

103 Zika virus (ZIKV) is an emerging pathogen causally associated with serious sequelae in fe

104 .IMPORTANCE Influenza A virus is an airborne pathogen causing seasonal epidemics and occasional pande

105 discovery of much-needed drugs against these pathogens challenging.

106 e its veterinary relatives, the oculogenital pathogen Chlamydia trachomatis evolved as a commensal or

107 colonization of mice by the EPEC-like mouse pathogen Citrobacter rodentium.

108 d claudin-2 upregulation drives diarrhea and pathogen clearance.

109 ia and Europe is a canonical example of host-pathogen coevolution.

110 nder- or overestimation of disease risks and pathogen concentrations, depending on the context.

111 For many gram-positive pathogens, conjugative plasmid transfer is an important

112 asmodium falciparum and related apicomplexan pathogens contain an essential plastid organelle, the ap

113 Many invasive bacteria establish pathogen-containing vacuoles (PVs) as intracellular nich

114 site for many immunological functions, from pathogen containment to the differentiation of helper T

115 The prevalence of potential pathogens cultured from induced sputum specimens and qua

116 ic metabolites, with important functions for pathogen defence responses.

117 We show that the processes underlying pathogen defence senescence differ between males and fem

118 ral genes involved in disease resistance and pathogen defense.

119 Pathogens deliver effectors into plant cells to suppress

120 In vertebrates, pathogen-derived DNA is sensed in the cytosol by cGAS, w

121 While many pathogen-derived phospholipases also manipulate the immu

122 be caused by none, one, some, or all of the pathogens detected).

123 Here we assess their effects on bacterial pathogen detection by both culture and polymerase chain

124 erous pathogens and is recruited to sites of pathogen detection where it accumulates within papillae.

125 t is clear that the use of CIDTs for enteric pathogen detection, including both antigen detection and

126 he high prevalence of MRSA and MDR bacterial pathogens dictate the need for effective prevention as i

127 immunotherapeutics for additional infectious pathogens.DNA-delivered monoclonal antibodies (DMAbs) ca

128 transmission, case observation, within-host pathogen dynamics and mutation.

129 i, we show that failure to consider biphasic pathogen dynamics can lead to substantial under- or over

130 accommodation of beneficial microbes and in pathogen elimination.

131 stic and frequently drug-resistant pulmonary pathogen especially in cystic fibrosis sufferers.

132 Many intracellular pathogens exploit host secretory trafficking to support

133 It is well established that viral pathogens exploit PD to spread between cells, but it has

134 yer provides a critical host defense against pathogen exposure and epithelial injury, yet little is k

135 after queen loss and immune activation after pathogen exposure).

136 human cytomegalovirus (HCMV), a significant pathogen for immunocompromised individuals.

137 l using Porphyromonas gingivalis, a keystone pathogen for periodontitis, revealed reduced neutrophils

138 terium tuberculosis has succeeded as a human pathogen for tens of thousands of years thanks to its ab

139 ;Il10(-/-) mice and exposed them to specific-pathogen-free (SPF) or colorectal cancer-associated bact

140 en made, over 30 years, to eradicate a human pathogen from the world for the second time ever.

141 fampicin and clarithromycin against the same pathogens from 16 to 32 mug/mL to nanomolar levels.

142 Whole-genome sequencing of pathogens from host samples becomes more and more routin

143 ith the environment, particularly to protect pathogens from immune surveillance and host defenses.

144 Humans can be exposed to pathogens from poorly managed animal feces, particularly

145 ty by collecting antigens, particulates, and pathogens from the peritoneal cavity and, depending on t

146 ng chronic infections caused by a variety of pathogens, from persistent viruses to parasites.

147 trol agent Trichoderma atroviride, the plant pathogens Fusarium graminearum and Colletotrichum gramin

148 Growing availability of data on pathogen genetics and human ecology, coupled with comput

149 Fast, affordable sequencing of pathogen genomes - now a staple of the public health mic

150 so enables genomic analysis of heterogeneous pathogen genomes from patient samples and accurate detec

151 The Eukaryotic Pathogen Genomics Database Resource is a collection of d

152 lasminogen (hPg) to the surface of the human pathogen group A Streptococcus pyogenes (GAS) and subseq

153 of the PFOR-containing anaerobic periodontal pathogens, grown in both monospecies as well as multispe

154 Postinvasive immunity was shown to limit pathogen growth in the epithem and is actively suppresse

155 entral necrosis and cavitation, facilitating pathogen growth.

156 -stranded RNA (+RNA) viruses including human pathogens hepatitis C virus (HCV), Severe acute respirat

157 The fungal pathogen Histoplasma capsulatum minimizes detection of b

158 iving and non-pathogenic species, and select pathogen hosts.

159 en shown to suppress the growth of bacterial pathogens; however, the identification and mode of actio

160 ot hybridization have also been proposed for pathogen identification and detection.

161 on the cusp of unprecedented improvements in pathogen identification, antibiotic resistance detection

162 h an increased rate of infection by the same pathogen in both transplant procedures.

163 ned and commercialized for detection of this pathogen in food and water.

164 yromonas gingivalis is considered a keystone pathogen in the disease and is capable of elevating the

165 f 14 patients with CPr had at least one oral pathogen in their prostatic secretions.

166 vel, potent tool to study infection with the pathogen in vitro and in vivo and the immune response to

167 in plant defense machinery against microbial pathogens in Arabidopsis thaliana.

168 lication in the detection of low-copy-number pathogens in complex samples.

169 f cold plasma for inactivation of food-borne pathogens in foods is established.

170 loped icosahedral viruses that are important pathogens in many animal species, including humans.

171 defense responses against insects and fungal pathogens in Pinus species, increasing current knowledge

172 to have evolved from human interactions with pathogens in the microbial world.

173 umonia) and/or specificity (eg, detection of pathogens in upper respiratory tract specimens, which ma

174 age-associated bacteria, including potential pathogens, in the tropics this study compared the abunda

175 ly protects cells against various toxins and pathogens including viruses, intracellular bacteria and

176 family is comprised of many important human pathogens including yellow fever virus (YFV), dengue vir

177 xodes scapularis ticks harbor numerous human pathogens, including Anaplasma phagocytophilum, the agen

178 The transmission of insect-borne plant pathogens, including viruses, bacteria, phytoplasmas, an

179 are thus shown to be partially secondary to pathogen-induced inflammation.

180 syncytial virus (RSV) remains a major human pathogen, infecting the majority of infants before age t

181 rentiation in vitro in response to bacterial pathogen infection.

182 to be best equipped to protect the host from pathogen infection.

183 d resistance and basal immunity to bacterial pathogen infection.

184 sease might also have viral or intracellular pathogen infections.

185 processing can be an important part of host-pathogen interactions in other systems, suggesting inter

186 in which to study the consequences of plant-pathogen interactions on fertility and the evolution of

187 spite the high evolutionary pressure in host-pathogen interactions, it is still widely assumed that g

188 l to provide deeper insights into other host-pathogen interactions.

189 N, causing delays in recruitment to the host-pathogen interface.

190 ry balance of immune recognition during host-pathogen interplay.

191 s the immune system to protect the host from pathogen invasion.

192 mediator of the adaptive immune response to pathogens, it has been shown to be involved in several n

193 Macrophage intracellular pathogen killing is defective in cystic fibrosis (CF), d

194 During the past decade, knowledge of pathogen life history has greatly benefited from the adv

195 discuss how the life history of facultative pathogens likely often results in ecological tradeoffs a

196 growth and development of the important rice pathogen Magnaporthe oryzae in leaf cells.

197 Intracellular pathogens manipulate host organelles to support replicat

198 Cultured human pathogens may differ significantly from source populatio

199 train motivates finding strain-specific host-pathogen mechanisms.

200 How cells respond to pathogen-mediated disruption of gene expression to never

201 in pathway in effector-host interactions and pathogen-mediated host protein stability in order to pro

202 Rather than compromising host defenses, pathogen-mediated inhibition of anorexia increased host

203 As an important human respiratory pathogen, molecular detection is an indispensable tool f

204 fter erythrocyte invasion, the intracellular pathogen must increase host cell uptake of nutrients fro

205 facilitates selective autophagy of the human pathogen Mycobacterium tuberculosis (Mtb).

206 , RSV's importance as a largely unrecognized pathogen of debilitated older people is increasingly evi

207 brio parahaemolyticus, a significant enteric pathogen of humans, the roles of these regulators in pat

208 bacter nosocomialis, are opportunistic human pathogens of increasing relevance worldwide.

209 mportance of GA to both fungal and bacterial pathogens of rice.

210 identify inhibitors for the many other viral pathogens of significance that require IMPalpha/beta1 in

211 rmine engineering controls for opportunistic pathogens (OPs).

212 They compete for iron with soil-borne pathogens or induce a systemic resistance that shares ea

213 espiratory tract colonization with bacterial pathogens, or both.

214 Pathogen- or microbe-associated molecular patterns (PAMP

215 Key pathogens P. gingivalis, T. forsythia, T. denticola, P.

216 ar proteome during infection by the oomycete pathogen Phytophthora capsici.

217 Detection of pathogens present in food and water is essential to help

218 a ubiquitous host molecule targeted by many pathogens, promotes vascular interactions of the Lyme di

219 ection of databases covering 170+ eukaryotic pathogens (protists & fungi), along with relevant free-l

220 lopment and respiration in the opportunistic pathogen Pseudomonas aeruginosa PA14.

221 The opportunistic pathogen Pseudomonas aeruginosa produces the cationic ex

222 ondary metabolite by the opportunistic human pathogen, Pseudomonas aeruginosa.

223 PopP2, a YopJ effector produced by the plant pathogen Ralstonia solanacearum, in complex with inosito

224 Bacterial pathogens recruit circulating proteins to their own surf

225 Among pathogen-related factors influencing the outcome of P. a

226 l immune defense mechanism targeting diverse pathogens replicating in cytosolic membrane structures.

227 Effective T cell responses against invading pathogens require the concerted production of three key

228 Borrelia burgdorferi, the bacterial pathogen responsible for Lyme disease, modulates its gen

229 y changes upon exposure to different enteric pathogens, resulting in increased interepithelial cell (

230 lish these replicative niches, intracellular pathogens secrete various virulence proteins, called eff

231 eview the history and emergence of ZBP1 as a pathogen sensor and a central regulator of cell death an

232 This process benefits the pathogen since it enhances bacterial dispersal, but is d

233 We used McNemar's test to do pathogen-specific analyses, and generalised estimating e

234 orts, vaccines are being developed to induce pathogen-specific SIgA in addition to systemic immunity

235 es antimicrobial peptide production, whereas pathogen-specific Vgamma4 cells function in adaptive imm

236 /SCID/IL2Rgamma mice were used to assess for pathogen-specificity and evidence of nonspecific allorea

237 Host-generalist pathogens sporadically infect naive hosts, potentially t

238 model organism Neurospora crassa, the human pathogen Sporothrix schenckii, and the ergot fungus Clav

239 s a receptor on the surface of the bacterial pathogen Staphylococcus aureus that extracts heme from h

240 The Gram-positive pathogen Staphylococcus aureus uses one primary resistan

241 in clot-and show that the common blood-borne pathogen Staphylococcus epidermidis influences this in v

242 timing, outbreak sizes) under which virulent pathogen strains such as 'Ug99' (5,6) pose a threat from

243 imary Mvarphis infected with the common lung pathogens Streptococcus pneumoniae, Legionella pneumophi

244 Many intracellular pathogens subvert host membrane trafficking pathways to

245 oonotic viruses, including significant human pathogens such as Ebola and influenza viruses.

246 utative toxin-antitoxin gene pairs, and some pathogens such as Mycobacterium tuberculosis have over 9

247 Exposure of Africans to fatal pathogens, such as Plasmodium falciparum, Lassa Virus an

248 nt of vaccines against complex intracellular pathogens, such as Plasmodium spp., where protection is

249 ess, often accompanied by major increases in pathogen susceptibility.

250 ts, a few well-studied or purely theoretical pathogen systems, and a lack of studies occurring at the

251 We found the periodontal pathogen Tannerella forsythia to be associated with high

252 iew, we focus on how intracellular bacterial pathogens target innate immune signaling, the unfolded p

253 a provide information on 4460 genes from 264 pathogens tested on 176 hosts in 8046 interactions.

254 apneumovirus (HMPV) is a recently discovered pathogen that affects human populations of all ages worl

255 us (EBOV) is a high-priority, emerging human pathogen that can cause severe outbreaks of hemorrhagic

256 Bordetella pertussis is a human pathogen that can infect the respiratory tract and cause

257 true for the group A Streptococcus (GAS), a pathogen that causes both invasive (e.g., necrotizing fa

258 sahii (T. asahii) has emerged as a dangerous pathogen that causes rare but life-threatening infection

259 Reovirus is an avirulent pathogen that elicits protective immunity, but we discov

260 monocytogenes is a facultative intracellular pathogen that escapes from phagosomes, grows in the host

261 ZIKV is a rapidly spreading mosquito-borne pathogen that has been linked to Guillain-Barre syndrome

262 mmunity against a naturally occurring murine pathogen that infects the thymus and establish a novel i

263 se complex interactions between the host and pathogen that lead to metal homeostasis provide several

264 dia trachomatis is an obligate intracellular pathogen that resides in a membrane-bound compartment, t

265 onavirus (MERS-CoV) is an important emerging pathogen that was first described in 2012.

266 of cell death important in defenses against pathogens that can also result in a potent and sometimes

267 Adenoviruses are prevalent human pathogens that can cause a multitude of diseases, such a

268 ble to prevent colonization by two bacterial pathogens that cause mortality in neonates.

269 genera Norovirus and Sapovirus are important pathogens that cause severe acute gastroenteritis in bot

270 s), several of which are related to zoonotic pathogens that cause severe disease in humans.

271 l compartments, it reduces cell infection by pathogens that depend on this pathway to invade cells.

272 rucella species are infectious intracellular pathogens that replicate in professional and non-profess

273 lmonella enterica are invasive intracellular pathogens that replicate within a membrane-bound compart

274 ransmission of the 3 most common blood-borne pathogens, the natural history of early HCV infection, a

275 siella, Shigella, and Yersinia opportunistic pathogens, the structure of GusR has not been examined.

276 tors of virulence gene transcription in many pathogens; they also control housekeeping genes.

277 responses are tailored to different types of pathogens through differentiation of naive CD4 T cells i

278 c fibrosis airways do not respond to inhaled pathogens, thus favoring infection and inflammation that

279 ver, microbial strain typing allows zoonotic pathogens to be categorised, and the relative frequencie

280 l to combat infection drive the evolution of pathogens to counteract or sidestep them.

281 Dendritic cells (DCs) are activated by pathogens to initiate and shape immune responses.

282 at DHMA acts as a molecular beacon to target pathogens to their preferred sites of infection in vivo.

283 cal role in revealing the contributors (i.e. pathogens) to the biological or medical status of microb

284 by C. jejuni, and possibly other intestinal pathogens, to survive in the presence of bile.

285 he host phagosomal transport systems and the pathogen transporter may serve as therapeutic targets fo

286 s pattern recognition receptors facilitating pathogen uptake, antigen processing, and immunomodulatio

287 riety resistant to the powdery mildew fungal pathogen using the CRISPR/Cas9 technology.

288 Commensal bacteria protect against invading pathogens using many strategies.

289 solation and detection of multiple bacterial pathogens via magnetic separation and SERS.

290 d with the emergence of vancomycin-resistant pathogens (VRSA and VRE), the studies pave the way for t

291 Fungal pathogens, which can occupy distinct host tissues that h

292 ance, particularly in Gram-negative hospital pathogens, which has led to renewed efforts in antibioti

293 mimic the synergistic immune-stimulation of pathogens, while being safe.

294 aphylococcus aureus is a medically important pathogen with an abundance of virulence factors that are

295 Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers.

296 RR genes to generate resistance to unrelated pathogens with completely different lifestyles and route

297 estock in the family Bovidae shared the most pathogens with swine (82%).

298 cetes include many important saprophytes and pathogens, with the latter exhibiting necrotrophy, biotr

299 sistance and the emergence of multiresistant pathogens worldwide.

300 n agreement with a role in defending against pathogens, XBAT35.2 interacts with defense-related Accel