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1 GRP2 variants that were biallelic and likely pathogenic.
2  amino acid change (LAMB2-S83R) alone is not pathogenic.
3 ters the oral microbiota and renders it more pathogenic.
4 e a 50% reduction of TBK1 protein levels are pathogenic.
5 the oral microbiota of diabetic mice is more pathogenic.
6  and improve outcomes associated with highly pathogenic A(H5N1).
7 in M2 in minimal medium and demonstrate that pathogenic Acinetobacter species produce both a function
8                                              Pathogenic Acinetobacter species, including Acinetobacte
9 f known genetic risk factors and potentially pathogenic alleles identified in future studies.
10 lls and new molecular pathways that regulate pathogenic alloreactivity.
11  (TCGA) data set and observe that bi-allelic pathogenic alterations in homologous recombination (HR)
12 ne, which contains the VNDT motif, is highly pathogenic and causes lethality in a mouse model.
13 ents and mechanisms of type VII secretion in pathogenic and environmental bacteria.
14 vel strategies to effectively address highly pathogenic and lethal infections stemming from bacterial
15                                              Pathogenic and likely pathogenic variants were classifie
16 ications for the stability of cooperation in pathogenic and non-pathogenic environments, in biotechno
17         The numerous differences between the pathogenic and nonpathogenic infections with regard to d
18 HFrEF; EF <40%) is well established, but its pathogenic and prognostic significance in HF with midran
19 isms, they also have the potential to become pathogenic and promote autoimmune and inflammatory disea
20                            In contrast, both pathogenic and protective roles have been associated wit
21 atics tools classified 11 variants as likely pathogenic and showed no association with diabetes risk
22 thod, MutPred-LOF, for the discrimination of pathogenic and tolerated variants that can also generate
23 erplay between host non-self RNA sensors and pathogenic arenaviruses, which also provides insights in
24                   Our work thus elucidates a pathogenic, as opposed to protective, role for IL-17A du
25 as well as understanding the cytotoxicity of pathogenic assemblies.
26 from disrupting the autoprotective role that pathogenic ataxin-3 has against itself, which depends on
27  tolerance and reduced the amount of GCs and pathogenic autoantibody.
28 require resolution for full understanding of pathogenic autoimmunity.
29 rnative clade 2.3.4.4 CVVs.IMPORTANCE Highly pathogenic avian influenza (HPAI) A(H5) viruses have cir
30                                   The highly pathogenic avian influenza (HPAI) H5N1 viruses continue
31 morbidity and mortality annually, and highly pathogenic avian influenza (HPAI) viruses along with oth
32 birds have the potential to mutate to highly pathogenic avian influenza (HPAI) viruses, but such viru
33                         Introductions of low-pathogenic avian influenza (LPAI) viruses of subtypes H5
34 mic H1N1 influenza A (H1N1) virus and highly pathogenic avian influenza A (H5N1) virus induce express
35 le-genome sequences of representative highly pathogenic avian influenza A(H5) viruses from Vietnam we
36 ry team investigated 2 human cases of highly pathogenic avian influenza A(H5N1) virus infection, dete
37          Mutation and reassortment of highly pathogenic avian influenza A(H5N1) viruses at the animal
38                      The emergence of highly pathogenic avian influenza H5N1 viruses has raised conce
39 proteins and nucleic acids from a variety of pathogenic bacteria and operates in a continuous and ult
40 of the heme-sensing and transport systems of pathogenic bacteria and the potential of these systems a
41                                              Pathogenic bacteria are extremely efficient in orchestra
42           Colonization of the endometrium by pathogenic bacteria ascending from the lower female repr
43                                     As such, pathogenic bacteria have evolved sophisticated cell surf
44  that can evaluate antibiotic resistance for pathogenic bacteria in order to deliver targeted antibio
45 e conserved in other bacteria, including the pathogenic bacteria lacking the assembly factor CcoH as
46             When C. elegans first encounters pathogenic bacteria P. aeruginosa, SOD-1 is induced in t
47                                              Pathogenic bacteria secrete toxins and degradative enzym
48 -inositol phosphatases (PTPLPs) from the non-pathogenic bacteria Selenomonas ruminantium (PhyAsr) and
49 have served as powerful therapeutics against pathogenic bacteria since the golden age of antibiotics
50                              Salmonellae are pathogenic bacteria that cause significant morbidity and
51 cal for the expression of virulence genes in pathogenic bacteria that infect warm-blooded hosts.
52 ectins play important roles in infections by pathogenic bacteria, for example, in host colonization,
53 trains of Zika and Dengue virus, distinguish pathogenic bacteria, genotype human DNA, and identify mu
54 ellular processes, inhibiting growth of many pathogenic bacteria, including the major respiratory pat
55 per and zinc, altered gut microbiota to more pathogenic bacteria, increased inflammatory markers, and
56  of interest as biosensors, particularly for pathogenic bacteria.
57 in of diverse prokaryotic species, including pathogenic bacteria.
58 romised by the evolution of resistance among pathogenic bacteria.
59  secretion system found in environmental and pathogenic bacteria.
60 rms a lethal pore on the cellular surface of pathogenic bacteria.
61                                       In the pathogenic bacterium Pseudomonas aeruginosa PA14, antibi
62  experiments to address this question in the pathogenic bacterium, Pseudomonas aeruginosa Although pu
63                 We utilized the fast-growing pathogenic basiodiomycete forming an induced DOPA-melani
64 not only a mechanism by which T cells become pathogenic before entering the CNS, but also the potenti
65                             Patients without pathogenic BRCA1 and BRCA2 alterations showed elevated d
66 ated ancestor and the mammalian host-adapted pathogenic Brucella species.
67                                           As pathogenic cargos, viruses require MTs to transport to a
68     This review captures recent knowledge on pathogenic CD4(+) T cells in asthmatic patients by drawi
69                                              Pathogenic CD4(+) T cells within affected tissues may be
70                    Moreover, we identified a pathogenic CD8(+) T cell MPO epitope (MPO431-439) and fo
71 st in metabolic pathways between healthy and pathogenic cells, there is opportunity for selective reg
72 otein domains harbored the highest number of pathogenic changes.
73 ost of studies have focused on molecular and pathogenic characterization of PEDV, whereas there were
74  female) presented with pathogenic or likely pathogenic CNVs (0.08-18.9 Mb).
75                To evaluate the prevalence of pathogenic CNVs and identify possible candidate CNVs and
76                       The high prevalence of pathogenic CNVs in this study highlights the importance
77 hensive genome sequencing did not reveal any pathogenic coding or canonical splicing mutations within
78 ion and formation of a P. gingivalis-induced pathogenic community.
79 aS at vesicles, and abrogating multimers has pathogenic consequences.
80 ciated CAFs, where it is responsible for key pathogenic contributions in this disease.
81  in identifying the risk factors for and the pathogenic contributors to the syndrome and in character
82 eurodevelopmental disorders, we suggest that pathogenic de novo variants in GRIA4 lead to intellectua
83                         SEP4-mediated fungal pathogenic development, including IFS formation, was val
84 a and, potentially, other forms of bacterial pathogenic disease.
85 African swine fever virus (ASFV) is a highly pathogenic, double-stranded DNA virus with a marked trop
86 lication rate almost completely retained the pathogenic E. coli in the subsurface, suggesting that ut
87  bidirectional manner between protective and pathogenic effector states.
88 inflammation was mediated by IL-5-expressing pathogenic effector Th2 cells and was independent of TCR
89 dges the gap between genetic association and pathogenic effects and yields novel insights into the un
90 c IFN regulated proteins responsible for the pathogenic effects of ADAR1 mutation are unknown.
91                   These findings support the pathogenic effects of extracellular histones in that pul
92 ay promote or impede such signalling and the pathogenic effects of ganglioside antibodies.awx012media
93 ectious diseases, and may have protective or pathogenic effects, depending on the tissue and disease
94 sion of the nrf operon promoter from various pathogenic enteric bacteria.
95 iota are sufficient to limit colonization of pathogenic Enterobacteriaceae.
96 lected for the precise traits that now allow pathogenic enterococci to survive desiccation, starvatio
97 and acid-adapted bacterial species promote a pathogenic environment, leading to demineralization.
98 ability of cooperation in pathogenic and non-pathogenic environments, in biotechnological application
99 rous studies have examined the prevalence of pathogenic Escherichia coli in poultry and poultry produ
100 d model might be useful to investigate early pathogenic events and prove molecular concepts in patien
101 ated mRNA (HTTexon1) that encodes the highly pathogenic exon 1 HTT protein.
102      The amyloid-beta peptide (Abeta), a key pathogenic factor in Alzheimer disease, induces profound
103 monstrates that RNA misprocessing is a major pathogenic factor in CDM and provides novel mouse models
104                     Hyperglycemia is a major pathogenic factor that promotes diabetic nephropathy, bu
105 t elevated levels of oxysterols might be key pathogenic factors in SPG5.
106    Our findings suggest that AT and ClfA are pathogenic factors that could be therapeutically targete
107                            We aimed to model pathogenic fibroblast migration in SSc in order to ident
108 lial cells (serving as the first hit) - into pathogenic fibrosis.
109 elial cells much more efficiently than other pathogenic flaviviruses because it binds Gas6 more avidl
110                                        It is pathogenic for a variety of vertebrate hosts, in which E
111 to the role of bacteriophages as potentially pathogenic for mammals and their possible implication in
112  additive roles in facilitating each other's pathogenic functions in PD.
113 , and considers changes in the wall of plant-pathogenic fungi during on and in planta growth, followi
114 hat are essential for the virulence of human pathogenic fungi.
115 ion, the recombinant strains were similar to pathogenic G1 strains, but in the non-structural region
116 d genomic sequencing to identify potentially pathogenic gene variants in families in which a person h
117  The primary outcome was identification of a pathogenic germline mutation associated with cancer pred
118                  Antimicrobial resistance in pathogenic gram-negative bacteria is one of the most pre
119                                         Many pathogenic Gram-negative bacteria use the type III secre
120                  Pseudomonas aeruginosa is a pathogenic gram-negative organism that has the ability t
121 family Tectiviridae can infect commensal and pathogenic Gram-positive and Gram-negative bacteria.
122 tic Hantaan virus (HTNV), the most prevalent pathogenic hantavirus.
123                                              Pathogenic hantaviruses bind to the plexin-semaphorin-in
124 ytomegalovirus (HCMV) is a ubiquitous, human pathogenic herpesvirus.
125                                          The pathogenic HIST1H1E mutations are predicted to result in
126                                              Pathogenic HIV or lymphocytic choriomeningitis virus chr
127 nger sequencing and discovered a potentially pathogenic, homozygous variant, c.240C > G (p.Phe80Leu).
128 sophila HD model, we find that nonaggregated pathogenic Htt acts locally at synaptic terminals to dis
129                                              Pathogenic Htt is present largely in a nonaggregated for
130                               The effects of pathogenic Htt on synaptic growth arise from defective s
131                                              Pathogenic human coronaviruses (CoVs), such as the sever
132 e susceptibility to IAV in males and augment pathogenic immune responses in the lung, including activ
133 vulnerability to schizophrenia (SZ), but the pathogenic impact of SZ-risk mutations on corticogenesis
134    The DGCR2 missense SZ-risk mutation had a pathogenic impact on projection neuron laminar allocatio
135 man pancreatic islets, the tissue of primary pathogenic importance for diabetes.
136                   Indeed, vDeltaK1L was less pathogenic in intradermally infected mouse ear pinnae.
137  cases and 16 novel variants predicted to be pathogenic in silico in 15 cases.
138 y cytokines that can be elevated in RA evoke pathogenic increases in sympathetic activity and reducti
139 stood how innate cells integrate qualitative pathogenic information to generate tailored protective a
140  representative immunodominant epitopes from pathogenic insults.
141  immune activation markers, suggesting their pathogenic involvement in AIDS- or non-AIDS-related comp
142 onstrating that these APOL1 risk alleles are pathogenic is still lacking because the APOL1 gene is pr
143                                    Moreover, pathogenic KIF1Bbeta mutations identified in neuroblasto
144                                     Although pathogenic LCs have been characterized biochemically, li
145 sis mainly by regulating the accumulation of pathogenic leukocyte subtypes, which drive the fibrotic
146 ations were classified as pathogenic, likely pathogenic, likely benign and benign per the chance of c
147             The mutations were classified as pathogenic, likely pathogenic, likely benign and benign
148 ic testing identified variants classified as pathogenic, likely pathogenic, or uncertain significance
149                                              Pathogenic LRRK2 R1441G/C and Y1699C mutants that promot
150                     Moreover, an increase of pathogenic lymphocyte infiltration and the secretion of
151 tu during AH, providing a previously unknown pathogenic mechanism and new avenues for treatment.
152            Our findings identify a potential pathogenic mechanism attributable to MATR3 mutations and
153 ling in 22q11DS mice, and it may mediate the pathogenic mechanism of 22q11DS-related psychosis and co
154 itochondrial calcium deregulation is a novel pathogenic mechanism of cognitive deficiencies in schizo
155              However, the cellular basis and pathogenic mechanism of the SLC25A46-related neuropathie
156   The need for individualized definitions of pathogenic mechanisms before initiating therapy extends
157 ease heterogeneity and poor understanding of pathogenic mechanisms hampers the identification of ther
158                                 However, the pathogenic mechanisms of fungal GH12 proteins have not b
159                                 However, the pathogenic mechanisms of most of these SNPs remain elusi
160                                          The pathogenic mechanisms of these viruses are largely unkno
161                Our data demonstrate that the pathogenic mechanisms responsible for chronic inflammato
162  the course of MS is driven by the very same pathogenic mechanisms responsible for the disease, the a
163  humans, and used this system to explore the pathogenic mechanisms resulting from the sporadic Alzhei
164 nced considerably in recent years, revealing pathogenic mechanisms that potentially underlie ciliopat
165                         Our findings provide pathogenic mechanisms to explain the association between
166 ovide a cellular phenotype for investigating pathogenic mechanisms underlying AS and identifying nove
167 milar in Ig-MPGN and C3G, suggesting similar pathogenic mechanisms.
168  in the same individuals, suggesting similar pathogenic mechanisms.
169 n and human disease, and delineate potential pathogenic mechanisms.
170      Skin provides the first defense against pathogenic micro-organisms and is also colonized by a di
171 m 40% of patients with RA was positive for a pathogenic microbe.
172 rtant roles in the innate immune response to pathogenic microbes, but mounting data suggest these pat
173 th activity against human opportunistic food pathogenic microbes, have been isolated from the ethyl a
174 conserved molecular motifs characteristic of pathogenic microbes.
175 nd catabolic microcompartments found in many pathogenic microbes.
176 ferring resistance to various antibiotics in pathogenic microbes.
177 en normal skin microbial interactions versus pathogenic microbial interactions in wound repair is imp
178 hoglycerate isomers is catalysed in numerous pathogenic microorganisms by a cofactor-independent muta
179        MacB represents an ABC transporter in pathogenic microorganisms with unique structural feature
180 related to the presence of food spoilage and pathogenic microorganisms.
181     Our findings establish L35P as the first pathogenic missense mutation in PALB2 and directly demon
182 ity of Ceftriaxone/Cefotaxime against highly pathogenic MRSA infection.
183                            MRT aims to avoid pathogenic mtDNA transmission between generations by mat
184                              Strikingly, one pathogenic mutation T233A (NCBI accession no.
185      Reminiscent of our earlier studies on a pathogenic mutation that generates full-length M1 and M8
186 e is not sufficient to reveal the underlying pathogenic mutation.
187      A comparison of the distribution of the pathogenic mutations along the length of DYRK1A with tha
188                                              Pathogenic mutations cause a loss of function of the enc
189                                We identified pathogenic mutations in 36 of 204 (17.6%) patients.
190  single, in vivo model for studying multiple pathogenic mutations in ATP7 proteins using Drosophila m
191 effective index to investigate the effect of pathogenic mutations in RBP binding sites, especially th
192 understand the mechanistic changes caused by pathogenic mutations in the TNT1 region, six hypertrophi
193 e DNAm signatures were able to differentiate pathogenic mutations in these two genes from controls an
194 al insight into multiple mechanisms by which pathogenic mutations interfere with enzyme function, and
195 lysis of the gATP7-GFP transgenes containing pathogenic mutations showed that the function of ATP7 wa
196  validated on 99 newly-discovered genes with pathogenic mutations, the algorithm displays an excellen
197 ects bearing frontotemporal dementia-related pathogenic mutations.
198 second only to single nucleotide variants as pathogenic mutations.
199 s a system to dissect host interactions with pathogenic ncRNAs, using comprehensive transcriptome ana
200  Olfactomedin-4 might serve as a marker of a pathogenic neutrophil subset in patients with septic sho
201 quantifies the transport of Escherichia coli pathogenic O157:H7 and nonpathogenic K12 strains in wate
202 years; 11 male and 16 female) presented with pathogenic or likely pathogenic CNVs (0.08-18.9 Mb).
203        Seventy-five percent (43/57) harbored pathogenic or likely pathogenic variants in 10 genes.
204 une system, MG also detect "danger" signals (pathogenic or traumatic insult), become activated, produ
205 ed variants classified as pathogenic, likely pathogenic, or uncertain significance.
206 17 cells can protect against colonization by pathogenic organisms, they also have the potential to be
207       These interactions are impaired by the pathogenic p.C774R mutation.
208 es expressing human tau proteins harboring a pathogenic P301L MAPT mutation labeled with green fluore
209 S and SYNJ1 loss of function share a similar pathogenic pathway in deregulating DAergic neuron SV end
210 gest that the SK2 pathway may be a part of a pathogenic pathway in HD.
211                 An improved understanding of pathogenic pathways in AKI may identify novel therapeuti
212  be the causal relationship between multiple pathogenic pathways in human neurons obtained from idiop
213  position effects and their association with pathogenic phenotypes in 17 subjects with apparently bal
214 en ignored, contributor to the expression of pathogenic phenotypes.
215 stribution of the system among commensal and pathogenic phytobacteria suggests that the T6SS provides
216 , including one harboring the most prevalent pathogenic point mutation, and compared them with two ex
217 ed by host restriction genes Fv1 and Apobec3 Pathogenic potential maps to the env transmembrane subun
218 n, which can compete with the replication of pathogenic prions.
219 ype, is invaluable in further studies of the pathogenic process and therapeutics of PD.
220  intracellular cycle, but knowledge of these pathogenic processes is limited.
221               However, other studies suggest pathogenic properties of IL-22 during chronic liver inju
222   Even though GRG and OURT possess different pathogenic properties, there was significant overlap in
223  The factors that distinguish infectious and pathogenic protein aggregates from more innocuous ones a
224       Recent studies have reported spread of pathogenic proteins in the mammalian nervous system, but
225 ubstrates could be maintained when tested on pathogenic Pseudomonas aeruginosa.
226  better define the phenotype associated with pathogenic RASGRP2 variants, we compared high-throughput
227  signals is important for both symbiotic and pathogenic relationships, but is often poorly understood
228  syndrome coronavirus (SARS-CoV) is a highly pathogenic respiratory virus that causes morbidity and m
229  syndrome coronavirus (MERS-CoV) is a highly pathogenic respiratory virus that emerged from zoonotic
230 s (MERS-CoV) emerged in 2012 and is a highly pathogenic respiratory virus.
231 ated in lung disease induced by other highly pathogenic respiratory viruses.IMPORTANCE PF has many ca
232 eckel-Budimmir et al. (2017) reveal that the pathogenic response of mice to a Plasmodium berghei infe
233                 These findings demonstrate a pathogenic role for NPC:glioma interactions and potentia
234 beta (Abeta) is thought to play an essential pathogenic role in Alzheimer s disease (AD).
235  been conducted among women to determine its pathogenic role in the female reproductive tract.
236                                          The pathogenic role of ischemic heart disease (IHD) in heart
237                                 Although the pathogenic role of Mycoplasma genitalium in male urethri
238  proteinuria by anti-PD-L1 mAb supported the pathogenic role of these macrophages but not the PD-L1(-
239  et al. (2017) explore the protective versus pathogenic roles of DENV-immune antibodies in ZIKV infec
240 4/CD8 coreceptors play protective as well as pathogenic roles.
241 h which self is distinguished from non-self, pathogenic signals are recognized and eliminated, and ti
242                             To establish the pathogenic significance of these abnormalities, we inhib
243 d apoptosis) is specifically associated with pathogenic SIV infection and absent during the course of
244 s) and expand in lymph nodes (LNs) following pathogenic SIV infection in a cohort of vaccinated macaq
245 iated B cell dysfunction associated with the pathogenic SIV infection is characterized by loss of nai
246 ed to preinfection levels during the chronic pathogenic SIV infection, restoration is mainly due to a
247 ay play a significant role in the control of pathogenic SIV infection.
248 IMPORTANCE We previously demonstrated that a pathogenic SIVmac239 virus and a live-attenuated, deglyc
249  Sequencing and comparing the genomes of two pathogenic species of Batrachochytrium to those of close
250  antifungal agents to manage infections with pathogenic species such as Cryptococcus neoformans Becau
251 gi), along with relevant free-living and non-pathogenic species, and select pathogen hosts.
252 cell wall and essential virulence factors in pathogenic species.
253 tional characterization of the PerR from the pathogenic spirochete Leptospira interrogans, a rare exa
254 k between DPR proteins likely modifies their pathogenic status in C9ALS/FTD.
255 iants would not have been elevated to likely pathogenic status without knowing their de novo status.
256 higher TNF-alpha, IL-6, and IL-1beta) toward pathogenic stimuli, a process also mediated by JNK activ
257  for growth in vitro and in vivo of a highly pathogenic strain of C. jejuni.
258 nfection and thus prevent tumor induction by pathogenic strains of human papilloma virus (HPV).
259     Cfh deletion protected the mice from the pathogenic subretinal accumulation of mononuclear phagoc
260                                              Pathogenic T cells in individuals with rheumatoid arthri
261  T cell-mediated disease primarily driven by pathogenic T cells that produce high levels of IL-17 in
262 gamma) expression in T cells and to generate pathogenic TH17 cells in vivo.
263 IL-23 are required for in vivo transition of pathogenic Th17 cells to IFN-gamma producers.
264 ifferent from the gene expression profile of pathogenic Th17 cells.
265 nly a few members of the Parvoviridae family pathogenic to humans, especially young children and immu
266 e Campylobacter detectable in stormwater are pathogenic to humans.
267 ough the H5N8 virus has been only moderately pathogenic to mammalian hosts, virulence can still incre
268 s is a form of programmed cell death that is pathogenic to several acute and chronic diseases and exe
269 lays a crucial role in protective as well as pathogenic type 2 immune responses.
270 etic information of patients with a presumed pathogenic variant in KCNB1.
271 ve disorders, in which only one heterozygous pathogenic variant is identified.
272                    The siblings also had the pathogenic variant p.Ala13Thr variant in MYL2, a known g
273                         Laboratory-confirmed pathogenic variant.
274 ependently associated with the presence of a pathogenic variant.
275 ercent (43/57) harbored pathogenic or likely pathogenic variants in 10 genes.
276                             The frequency of pathogenic variants in 21 panel genes identified in 4161
277 ly actionable genomic findings (for example, pathogenic variants in BRCA1) identified in the course o
278 g, and linkage analysis to identify putative pathogenic variants in candidate disease genes for tooth
279 inant Robinow syndrome, we also found likely pathogenic variants in candidate genes GPC4 and RAC3, bo
280  in a series of patients with RP with likely pathogenic variants in CNGB1.
281 cedented power to detect three categories of pathogenic variants in particular: structural variants,
282 ures distinguished the cases associated with pathogenic variants in specific genes from each other or
283 ) or cone dystrophy (CD) harboring potential pathogenic variants in the CDHR1 gene.
284        We report 15 individuals with de novo pathogenic variants in WDR26.
285 entations because accurate interpretation of pathogenic variants is critical for delivering solid cli
286 u knock-out is lethal in mice, and recessive pathogenic variants of this gene have never been reporte
287  subdomains of KCNQ1 and the distribution of pathogenic variants therein.
288 other eight families segregation of multiple pathogenic variants was observed, affecting 19 genes tha
289                        Pathogenic and likely pathogenic variants were classified using American Colle
290                                              Pathogenic variants were identified in 48 of 180 childre
291  electroclinical syndrome is associated with pathogenic variation in SEPSECS.
292 ification and validation of novel putatively pathogenic variation in these regions.
293           The bacterial challenge test using pathogenic Vibrio anguillarum revealed that the larval d
294                        Because the growth of pathogenic vibrios in the natural environment is largely
295 ember of the Filoviridae family, is a highly pathogenic virus that causes severe hemorrhagic fever in
296 e population diversity of an important plant-pathogenic virus, we performed evolution experiments wit
297                                          All pathogenic viruses had modifications in the regulatory e
298                        We discuss a range of pathogenic viruses, including influenza virus, respirato
299             Apart from dysmorphic syndromes, pathogenic yields were highest for children with tuberou
300 The factors responsible for the emergence of pathogenic ZIKV are not understood at this time, althoug

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