ライフサイエンスコーパス: pathological feature

1 mechanisms that may be responsible for this pathological feature.

2 obliterans (BO) representing the predominant pathological feature.

3 nd the layers that were most affected by the pathological features.

4 disease with an expanding definition of its pathological features.

5 description of stage-dependent sequences of pathological features.

6 mation of alpha-syn are considered to be key pathological features.

7 k, survival, and clinical, radiographic, and pathological features.

8 dary objective was to correlate clinical and pathological features.

9 to intermittent pressure overload displayed pathological features.

10 ated with increased Th1 cytokines and unique pathological features.

11 etic etiologies and overlapping clinical and pathological features.

12 ingioma subgroups with distinct clinical and pathological features.

13 gnisable variants with distinct clinical and pathological features.

14 ts most frequently with similar clinical and pathological features.

15 mas with distinct clinical presentations and pathological features.

16 issue localization of deposits and for major pathological features.

17 represents the greatest risk factor for CTE pathological features, although clinicopathological corr

18 elevated extracellular glutamate is a common pathological feature among epilepsies with different eti

19 Shared pathological features among muscular dystrophies include

20 er's disease is characterized by two primary pathological features: amyloid plaques and neurofibrilla

21 himeric model for AD displays human-specific pathological features and allows the analysis of differe

22 s a different novel disorder with dissimilar pathological features and belongs to the growing number

23 line M(1) receptors (M(1)Rs) reduces AD-like pathological features and enhances cognition in AD trans

24 ice were studied at different ages for renal pathological features and function.

25 my series, obesity was associated with worse pathological features and higher biochemical recurrence

26 special stains, and IHC to characterize the pathological features and investigate the pathogenesis o

27 xacerbating AD-related cognitive decline and pathological features and provide critical preclinical e

28 the development of hallmark amyloid and tau pathological features and that long-term expression of t

29 that have both dysplastic and proliferative pathological features, and neither the International Wor

30 s, absence of specific clinical, imaging, or pathological features, and ongoing dependence for diagno

31 However, the unique pathological feature - appearance of the intranuclear in

32 These pathological features are also relevant to other common

33 d gonadal dysgenesis in humans, although the pathological features are distinct.

34 The defining pathological features are fluid-filled cysts developing

35 teristic of Niemann-Pick type C disease, the pathological features are not well understood.

36 en segment function is disrupted, a range of pathological features are presented.

37 translational models that reproduce the core pathological features are urgently needed to facilitate

38 S1P(1) agonism alone reduced pathological features as did fingolimod (maximally lymph

39 les (NFT), is considered the most predictive pathological feature associated with cognitive status in

40 expansion during inflammation and to certain pathological features associated with AML, emphasizing t

41 Neuritic dystrophy is one of the important pathological features associated with amyloid plaques in

42 s to date, we characterized the clinical and pathological features associated with hippocampal sclero

43 d-skull brain injury model that mirrors some pathological features associated with mild TBI in humans

44 1R) reduces food intake and improves several pathological features associated with obesity, such as d

45 of misfolded proteins in the cytosol are key pathological features associated with Parkinson's diseas

46 oglycan is sufficient to explain all complex pathological features associated with these diseases is

47 improves survival in patients with high-risk pathological features at radical prostatectomy at the co

48 ors recently recognized common molecular and pathological features between the 2 conditions.

49 ice exhibit enhanced amyloid and tau-related pathological features by the age of 15 months, in stark

50 e with ATXN1[30Q]-D776-induced disease share pathological features caused by ATXN1[82Q] having an exp

51 reatment with IL-13-PE can reverse important pathological features caused by inhalation of silica par

52 e well tolerated, producing no behavioral or pathological features characteristic of ALS/FTD and only

53 Both diseases share clinical and pathological features characteristic of excessive allerg

54 the miR-155-induced GM populations displayed pathological features characteristic of myeloid neoplasi

55 uclein (aSyn) misfolding and aggregation are pathological features common to several neurodegenerativ

56 spinal cord exhibited many key clinical and pathological features consistent with human ALS disease.

57 Clinical, radiological and pathological feature define CLIPPERS syndrome and are di

58 Statistical analysis of clinical and pathological features demonstrated that the expression o

59 ermediate filaments (IFs) represent the main pathological feature detected in neurons and other cell

60 Among other pathological features, DMD muscles show severely derange

61 ed gene copy number and certain clinical and pathological features have been associated with dramatic

62 Diverse pathological features have been identified, and their di

63 ns after early physiological, cognitive, and pathological features have developed.

64 ed whether axonal pathology is also an early pathological feature in a transgenic mouse model carryin

65 on, with synaptic dysfunction being an early pathological feature in aging and disease.

66 Defects in axonal transport are an early pathological feature in Alzheimer's disease and defectiv

67 Disruption to axonal transport is an early pathological feature in Alzheimer's disease.

68 sis and infiltrating T cells, is a prominent pathological feature in diverse models of dominantly inh

69 The hallmark pathological feature in most cases of ALS is nuclear dep

70 ed, and although demyelination is a hallmark pathological feature in MS, it is unclear to what extent

71 Aberrant protein aggregation is a dominant pathological feature in neurodegenerative diseases.

72 lia and infiltrating T cells, is a prominent pathological feature in neurodegenerative diseases.

73 ucin (MUC) genes MUC5AC and MUC5B is a major pathological feature in various airway diseases.

74 We revealed the same pathological features in a mouse model of human Adrenomy

75 Pathological features in Alzheimer's brains include mito

76 estigate several inflammatory and structural pathological features in bronchial biopsies of severe as

77 (ASM) hypertrophy and hyperplasia, important pathological features in chronic severe asthma, likely c

78 Somatostatin (SST) deficits are common pathological features in depression and other neurologic

79 ix, inflammation and fibrosis are the common pathological features in DMD, the underlying mechanisms

80 the need to evaluate the neurocognitive and pathological features in female carriers of the fragile

81 s that there is overlap of both clinical and pathological features in paralytic rabies and axonal Gui

82 cognitive dysfunction, which are invariable pathological features in patients with Alzheimer's disea

83 of microtubule-associated-protein-tau-based pathological features in some patients and the discovery

84 terial lipopolysaccharide, modulates AD-like pathological features in the 3xTg-AD mouse model and pro

85 The overlap of clinical and pathological features in the congenital myopathies has l

86 The pathological features in the lung resulting from SEA exp

87 oach may be applicable to a diverse range of pathological features in the retina and other organs.

88 s a neurodegenerative disease whose hallmark pathological features include a selective loss of dopami

89 Pathological features include loss of myocytes and fibro

90 Hallmark pathological features include T-cell mediated inflammato

91 Additional pathological features included cortical Lewy bodies, bra

92 se accurately recapitulate all the key human pathological features including brain enlargement, corti

93 o compared with regard to their clinical and pathological features including the lesion profiles.

94 D) is characterized by multiple, intertwined pathological features, including amyloid-beta (Abeta) ag

95 dult-onset inherited myopathies with similar pathological features, including hereditary inclusion bo

96 Cav-1 knockout retinas exhibited additional pathological features, including i) eNOS-independent enl

97 However, the molecular cause of many pathological features, including the frequently observed

98 The pathological features induced by RSV infection in HIS mi

99 ne lymphoma (MGZL) is extremely rare and has pathological features intermediate between NSHL and PMBL

100 ed macular degeneration (AMD) in which a key pathological feature is a thick extracellular sub-retina

101 prominent glial reactions, but whether this pathological feature is due primarily to cell proliferat

102 ess SMCs; however, a mechanism linking these pathological features is lacking.

103 dependently attenuated clinical symptoms and pathological features (leukocyte infiltration and demyel

104 These pathological features manifest behaviorally as positive

105 y-onset, profound hearing deficits and other pathological features mimicking human laminopathy associ

106 It is a pathological feature observed in certain tumors, referre

107 synthesis was required for induction of all pathological features observed both in vitro and in vivo

108 The major pathological features observed in post-mortem tissue fro

109 We describe here the clinical and pathological features observed in two unrelated females,

110 They share the common pathological feature of a hypoglycosylated form of alpha

111 ngs suggest that weight loss is an intrinsic pathological feature of Abeta accumulation and identify

112 t showed abnormal activation of GSK-3beta, a pathological feature of AD.

113 icate that activated caspase 3 defines a new pathological feature of ALS with intermediate-length ata

114 o evidence of muscle denervation, a cardinal pathological feature of ALS.

115 itive element transcript expression, a novel pathological feature of ALS/FTLD.

116 ta peptides (Abeta) in the brain is a common pathological feature of Alzheimer disease (AD).

117 al plaques and the cerebral vasculature is a pathological feature of Alzheimer disease and related di

118 -protein (Abeta) in the brain is a prominent pathological feature of Alzheimer disease and related di

119 f beta-amyloid (Abeta) deposits is a primary pathological feature of Alzheimer disease that is correl

120 Senile plaques are a prominent pathological feature of Alzheimer's disease (AD), but li

121 near amyloid plaques as a part of important pathological feature of Alzheimer's disease (AD).

122 yloid beta-protein (Abeta) in brain is a key pathological feature of Alzheimer's disease and related

123 as cerebral amyloid angiopathy, is a common pathological feature of Alzheimer's disease.

124 Excessive mucus production is an important pathological feature of asthma.

125 Insulitis is an important pathological feature of autoimmune diabetes; however, me

126 Metabolic reprogramming is a pathological feature of cancer and a driver of tumor cel

127 pH in the tumor micromilieu is a recognized pathological feature of cancer.

128 Bone loss is a typical pathological feature of chronic inflammatory bone diseas

129 Interstitial fibrosis, a common pathological feature of chronic kidney diseases, is ofte

130 Intestinal inflammation is the central pathological feature of colitis and the inflammatory bow

131 One main pathological feature of COPD is the loss of functional a

132 Interstitial fibrosis is a characteristic pathological feature of HCM and a risk factor for sudden

133 ircadian sleep disturbances are an important pathological feature of HD, that they arise from patholo

134 not primarily due to MSN loss, the defining pathological feature of HD.

135 as cross-beta sheet amyloids are a defining pathological feature of infectious prion disorders and a

136 ransporter 4 (GLUT4) in adipocytes, an early pathological feature of insulin resistance.

137 fy rapid complex I reactivation as a central pathological feature of ischemia-reperfusion injury and

138 Axon degeneration is a critical pathological feature of many neurodegenerative diseases.

139 Oxidative stress is a pathological feature of many neurological disorders; the

140 Oxidative stress, a pathological feature of many respiratory diseases, cause

141 Mucin hypersecretion is a major pathological feature of many respiratory diseases, yet c

142 3 is a major component, are a characteristic pathological feature of most ALS and FTD patients.

143 Fibrosis is a pathological feature of most chronic inflammatory diseas

144 Protein aggregates are a common pathological feature of most neurodegenerative diseases

145 on-hematological conditions and is a central pathological feature of myelofibrosis.

146 Protein aggregates are a common pathological feature of neurodegenerative diseases and s

147 Astrocytic necrosis is a prominent pathological feature of neuromyelitis optica (NMO) lesio

148 igra pars compacta, reproducing an important pathological feature of Parkinson disease.

149 demonstration that dopamine loss is the key pathological feature of Parkinson's disease (PD), and th

150 Striatal spine loss is a key pathological feature of Parkinson's disease (PD).

151 A pathological feature of Parkinson's disease is the prese

152 (LB) in the substantia nigra are a cardinal pathological feature of Parkinson's disease, but they oc

153 rebral amyloid angiopathy (CAA), is a common pathological feature of patients with Alzheimer's diseas

154 ession of SV2C within the basal ganglia is a pathological feature of PD.

155 osis of interstitial trophoblasts is a novel pathological feature of preeclampsia and SGA.

156 ascular wall is a key currently irreversible pathological feature of pulmonary hypertension, a progre

157 Activated microglia represent a common pathological feature of several neurodegenerative diseas

158 erates oligomeric intermediates, is a common pathological feature of several neurodegenerative disord

159 rphosphorylated, aggregated tau are a common pathological feature of tauopathies, including Alzheimer

160 is induced by neuronal damage and is also a pathological feature of the major aging-related neurodeg

161 A common pathological feature of these diseases is the accumulati

162 aberrant TDP-43 cross-linking is a prominent pathological feature of this disease.

163 ecrete sufficient quantities of insulin is a pathological feature of type-1 and type-2 diabetes, and

164 We describe clinical and pathological features of a case of paralytic rabies with

165 ts within the TREM locus are associated with pathological features of AD and aging-related cognitive

166 in those with diabetes is mediated by excess pathological features of AD or other related abnormaliti

167 M locus in relation to cognitive decline and pathological features of AD.

168 The Ctrp5(+/-) mice, which have most of the pathological features of age-related macular degeneratio

169 This review examines the pathological features of aggressive bladder cancer and c

170 s and ultimately progressed with clinical or pathological features of AIDS.

171 tion, hyperresponsiveness, and remodeling as pathological features of allergic asthma provoked by hou

172 These pathological features of allergic disorder, common in de

173 alpha-synuclein (alpha-syn), are predominant pathological features of Alzheimer's disease (AD) and Pa

174 Early pathological features of Alzheimer's disease (AD) includ

175 sfunction and the loss of synapses are early pathological features of Alzheimer's disease (AD).

176 plaque-localized neuro-inflammation are key pathological features of Alzheimer's disease (AD).

177 The key pathological features of Alzheimer's disease include syn

178 plaques and neurofibrillary tangles are key pathological features of Alzheimer's disease.

179 ion that null mutations in Atp13a2 can cause pathological features of both diseases in the same organ

180 The distinctive clinical and pathological features of C. lamprauges are compared with

181 tive stress and energy deficit are important pathological features of calpainopathy and possibly repr

182 y genes and pathways underlying the specific pathological features of cardiomyopathies.

183 Although the pathological features of clinically characterized Haller

184 All pathological features of collagen-induced arthritis (CIA

185 l genetic metabolic liver diseases share the pathological features of combined steatosis and cholesta

186 characterise the clinical, physiological and pathological features of copper-deficient peripheral neu

187 ases is valuable to gain insights into early pathological features of corticobasal degeneration and i

188 Our studies show that pathological features of DBA are recapitulated by iPSCs,

189 the hippocampus, recapitulating several key pathological features of dementia observed in human pati

190 and is one of the first areas to express the pathological features of dementia.

191 n in the 30% hypomorphs almost abolishes the pathological features of diabetic nephropathy, although

192 ALS patients and SOD1(G93A) mice, the first pathological features of disease manifest at the neuromu

193 plex and heterogeneous mental disorder, with pathological features of disrupted neuronal excitability

194 this monkey model mimicked the clinical and pathological features of early mild to moderate S. aureu

195 asts, were fully functional and mirrored the pathological features of EBS-MD myofibers, including the

196 la enterica serotype Typhimurium and exhibit pathological features of enteric salmonellosis that clos

197 lvement of the PA system on the clinical and pathological features of experimental allergic encephalo

198 Pseudomonas exotoxin (IL-13-PE) might affect pathological features of experimental silicosis.

199 rmeable retinal vessels, recapitulating some pathological features of familial exudative vitreoretino

200 sion, which is primarily responsible for the pathological features of FXS .

201 he first viable vertebrate model sharing key pathological features of GD in both neuronal and non-neu

202 but regardless of resolution of the cardinal pathological features of GM2 gangliosidosis, a point is

203 ns were found between any of the clinical or pathological features of hereditary breast cancer with s

204 in organotypic raft cultures, mirroring the pathological features of higher-grade intraepithelial le

205 These models recapitulate key pathological features of human diseases and provide acce

206 n1 mouse model effectively recapitulates the pathological features of human FAN1 deficiency.

207 ockout (PPT1-KO) mice mimic the clinical and pathological features of human INCL including rapid neur

208 edium-sized blood vessels, represent salient pathological features of human rickettsioses, the intera

209 However, the characteristic pathological features of INCL were almost completely abs

210 major contributing factor to the clinical or pathological features of infectious prion disease.

211 Changes in pathological features of intermediate AMD eyes were dete

212 immunocytochemical methods to determine the pathological features of intranuclear inclusions in astr

213 replicates hearing loss and the clinical and pathological features of LF will significantly increase

214 muscles, and that these characteristics are pathological features of LGMD2A.

215 t Atm signaling played critical roles in the pathological features of liver failure.

216 y mice faithfully recapitulated clinical and pathological features of meningeal infiltration seen in

217 ugar and its overconsumption exacerbates key pathological features of metabolic syndrome.

218 cohort often, but not exclusively, exhibited pathological features of microvasculitis and ischaemia;

219 Here we define the clinical and pathological features of MN and describe the experimenta

220 stems may lead to a greater understanding of pathological features of motivation, such as psychomotor

221 ns for the understanding of both natural and pathological features of motivation.

222 ingly recognised, however, that clinical and pathological features of MSA are broader than previously

223 ry demyelination in mice that mimics certain pathological features of multiple sclerosis.

224 can attenuate dramatically the clinical and pathological features of murine models of autoimmune dis

225 ng locus on chromosome 7 that influenced two pathological features of muscular dystrophy, muscle memb

226 ThT also suppressed pathological features of mutant metastable proteins and

227 in NASH and that IL-13 cytotoxin ameliorates pathological features of NASH in rat liver, indicating a

228 Microgliosis and astrogliosis are standard pathological features of neurodegenerative disease.

229 ssion with doxycycline on the NFT-associated pathological features of neuronal system deafferentation

230 with AQP4 plausibly account for the diverse pathological features of NMO: edema, inflammation, demye

231 immunocytochemical methods to determine the pathological features of nuclear and/or cytoplasmic incl

232 The hallmark pathological features of Parkinson's disease are Lewy bo

233 neurons in the locus coeruleus are important pathological features of Parkinson's disease.

234 We evaluated clinical, radiological and pathological features of patients referred for suspected

235 SVAS iPSC-SMCs recapitulate key pathological features of patients with SVAS and may prov

236 This model closely mimics the clinical and pathological features of pneumonia in human patients.

237 y undiagnosed CC and review the clinical and pathological features of previously reported cases.

238 rtex spongiform change, one of the classical pathological features of prion disease, resolves in prio

239 egulation of LIMK1 contributes to one of the pathological features of psoriatic epidermal lesions.

240 of auditory stimuli was associated with core pathological features of schizophrenia, increasing confi

241 Importantly, key pathological features of smoking-associated lung disease

242 cells of SSc patients may underlie the main pathological features of SSc including autoimmunity, vas

243 emorrhage and pleural effusion are prominent pathological features of systemic anthrax infection.

244 Notably, the pathological features of tau pathology in these diseases

245 udy reveals that glaucoma displays signature pathological features of tauopathies, including tau accu

246 geting antibody to rodents reduces or delays pathological features of TBI.

247 The pathological features of TDP-43 are distinct from those

248 n of CSF1 expression was consistent with the pathological features of tenosynovial giant-cell tumor.

249 ls results in an exacerbation of all 3 major pathological features of the AD phenotype: memory defici

250 al dysfunction and synaptic damage are early pathological features of the Alzheimer's disease-affecte

251 Attempts to link pathological features of the amygdala, which plays a key

252 s for FD that recapitulate the molecular and pathological features of the disease.

253 ease type 1a) were found to recapitulate key pathological features of the diseases affecting the pati

254 We propose that major pathological features of the DM brain result from disrup

255 Although the clinical and pathological features of the GFAP(-/-)Vimentin(-/-)PPT1(

256 elial cells and reproduces many clinical and pathological features of the more severe forms of diseas

257 e disease in mice resembling biochemical and pathological features of the mucopolysaccharidoses and p

258 zygous for Cln3 deletion showed two hallmark pathological features of the neuronal ceroid lipofuscino

259 Clinical and pathological features of the patients were analyzed.

260 these label-retaining cells exhibit all the pathological features of the primary disease.

261 HCC, especially in patients with pejorative pathological features of the primary tumor that could in

262 array studies, as well as with clinical and pathological features of the tumors and relapse and surv

263 Herein, we review the pathological features of these central nervous system in

264 We describe the clinical and pathological features of these infections and the phylog

265 unohistochemistry and evaluated clinical and pathological features of these patients.

266 blockade of ST2L with an mAb attenuated key pathological features of this model.

267 Although the pathological features of transplant vasculopathy are wel

268 ng of a single factor to eliminate c9FTD/ALS pathological features offers advantages over approaches

269 hypotonia and muscle weakness, and specific pathological features on muscle biopsy.

270 ts in favor of FBT on all measures of eating pathological features (P = .003 to P = .03 for all).

271 mains unclear whether the latter is itself a pathological feature, possibly associated with levodopa

272 Although they share common pathological features, protein aggregates form in differ

273 nd extracellular Abeta deposits are the main pathological feature recapitulated by mouse models, cell

274 recise molecular mechanisms underlying these pathological features remain elusive.

275 The latter group had pathological features resembling those with a final clin

276 hed, mainly for HHV-6A, which reproduce some pathological features seen in humans.

277 biological events that may contribute to the pathological features seen in PML lesions.

278 Further, they had pathological features similar to those of human triple-n

279 e alterations represent some of the earliest pathological features so far reported in neurons of muta

280 nerve and spinal cord lesions with specific pathological features such as eosinophilic and neutrophi

281 Pathological features such as HLA class I hyperexpressio

282 Other IBM-like pathological features, such as inclusion bodies and infl

283 Because of its distinct clinical and pathological features, such as lack of expression of CD2

284 :Rv3242c M. marinum strains showed prominent pathological features, such as severe emaciation, skin l

285 asomnia with sleep breathing dysfunction and pathological features suggesting a tauopathy.

286 The only pathological feature that could potentially explain this

287 cyte progenitors and demyelination are major pathological features that are particularly pronounced i

288 Axonal swelling and axonal loss were major pathological features that distinguish T2T1MTR regions f

289 rtical impact model to identify the specific pathological features that give rise to the diffusion te

290 asmic reticulum (ER) stress is among several pathological features that underlie beta-cell failure in

291 Consistent with these distinct pathological features, the ErbB2DeltaEx16 tumors exhibit

292 aracterized by a higher incidence of adverse pathological features, unique gene expression profiles a

293 e present with uniform clinical, genetic and pathological features, we further propose the disorder b

294 at onset, disease duration, and clinical and pathological features were collected when available.

295 t have distinct biological, biochemical, and pathological features were identified in transgenic mice

296 progression and early cognitive decline; the pathological features were striking and reminiscent of d

297 lar degeneration shares several clinical and pathological features with AD, the measurements were the

298 ic analyses of skeletal muscle reveal common pathological features with DM tissues: chains of central

299 r neuron survival, and Scyl1(-/-) mice share pathological features with many human neurodegenerative

300 far) along with a review of its imaging and pathological features, with treatment options.