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2 agnosis of schizophrenia among glutamatergic pathophysiologic abnormalities in psychiatric disorders.
3 a tool for evaluating one of the fundamental pathophysiologic abnormalities seen in heart failure (HF
4 erogeneous syndrome associated with multiple pathophysiologic abnormalities, including left ventricul
5 in HFpEF, reduced (worse) LA strain is a key pathophysiologic abnormality and is a stronger correlate
7 Syt10 underlying the response of neurons to pathophysiologic activity and provide new therapeutic pe
9 ia, promoting production of IL-1beta and the pathophysiologic activity of the NLRP3 inflammasome in v
11 apamycin (mTOR) complexes by physiologic and pathophysiologic albumin concentrations in proximal tubu
12 kdown of megalin mimicked all the effects of pathophysiologic albumin concentrations, which disrupt n
13 Uncontrolled inflammation is now considered pathophysiologic and is associated with many widely occu
16 n may lead to important understanding of the pathophysiologic and therapeutic management in these dis
17 these neuroimaging markers reflect distinct pathophysiologic aspects in CAA, no studies to date have
19 dosteronism, in HF and RHT, has provided the pathophysiologic basis for the inclusion of MRA in the o
20 first step towards better understanding the pathophysiologic basis of chronic antibody-mediated allo
21 presents mechanistic evidence related to the pathophysiologic basis of neonatal dysphagia as well as
23 ey have provided important insights into the pathophysiologic basis of these disorders and potential
25 te a key component of the chronic bronchitis pathophysiologic cascade that produces sputum and mediat
27 istinctly altered local environment, several pathophysiologic changes are found that may promote brea
28 ysfunction grading system and understand the pathophysiologic changes associated with various grades
29 r extremity ischemia is also associated with pathophysiologic changes in calf skeletal muscle, includ
32 one for use in future studies interrogating pathophysiologic changes in neuropsychiatric disorders a
33 d PTH secretion in vivo, we examined whether pathophysiologic changes in pHo can significantly alter
36 o date there is almost no information on the pathophysiologic changes within the cerebral spinal flui
38 , remodel abnormal circuitry relevant to the pathophysiologic characteristics of cocaine addiction.
40 scular smooth muscle cells (PAVSMCs) are key pathophysiologic components of pulmonary vascular remode
41 vel mechanism for triggering angiogenesis in pathophysiologic conditions characterized by prothrombin
42 PARs and their cofactors in physiologic and pathophysiologic conditions have the potential to influe
43 es of the role of PXR in the physiologic and pathophysiologic conditions of other cellular processes
44 standing of the role of the venous system in pathophysiologic conditions will allow intensivists to b
45 etachment from the GBM under physiologic and pathophysiologic conditions, including glomerular hypert
49 ven macrophage-mediated inflammation and its pathophysiologic consequences in sickle cell disease.
50 little is known regarding the molecular and pathophysiologic consequences of altered GSL biosynthesi
52 specificity of S1P1 activation in normal and pathophysiologic contexts in vivo and can be applied to
57 1 pathways selectively in podocytes mediates pathophysiologic crosstalk that influences mesangial arc
59 in biochemical pathways and how they promote pathophysiologic developments involving proinflammatory
61 ar vesicles will provide insights into their pathophysiologic, diagnostic, and therapeutic roles.
62 g body of literature demonstrating important pathophysiologic differences between ALI caused by diffe
65 cardiac and noncardiac comorbidities, valve pathophysiologic disorders, and echocardiographic measur
66 This work strongly supports the notion of pathophysiologic divergence between individuals with sch
68 ured a panel of biomarkers representing four pathophysiologic domains: "inflammation" (tumor necrosis
69 rexinoids would more effectively reverse the pathophysiologic effects of angiotensin II than an indiv
70 and function of ovarian theca cells and the pathophysiologic effects of hyperinsulinism on ovarian f
76 ations in pH elicited by neural activity and pathophysiologic events such as hypoxia-ischemia and sei
77 m of miRNA-mediated integration of the early pathophysiologic events that facilitate tissue remodelli
79 2 or HIF-1alpha can prevent or reverse these pathophysiologic events, restoring a state of insulin se
82 omerular hyperfiltration as a prognostic and pathophysiologic factor in diabetes may lead to improved
83 ferences may be the basis for the underlying pathophysiologic factors contributing to the development
84 of risk factors for MH may help clarify the pathophysiologic factors of MH and identify potential ne
85 ortical (CSTC) circuit dysfunction is a core pathophysiologic feature of obsessive-compulsive disorde
87 asthma that can induce several clinical and pathophysiologic features of asthma in sensitized subjec
88 f TLR7(-/-) mice induced all of the cardinal pathophysiologic features of asthma, including tissue eo
89 cell arteritis, and 1 of 193 (0.5%) for the pathophysiologic features of central retinal artery occl
91 volume (ECV) accumulation is one of the key pathophysiologic features of heart failure with preserve
92 This mouse model mimics the pathology and pathophysiologic features of human adult-onset branching
93 geable ranged from 29 of 199 (14.6%) for the pathophysiologic features of retinal detachment, 1 of 20
94 model of HCDD efficiently recapitulates the pathophysiologic features of the disease and demonstrate
95 yositis have unique clinical, pathologic and pathophysiologic features when compared with those with
96 ch disease, including 1 question about basic pathophysiologic features, 1 question about basic sympto
97 Th2-polarized inflammatory response may have pathophysiologic features, they are also efficient and e
101 hy and may represent an important underlying pathophysiologic foundation for cystoid macular edema in
105 onary disease (COPD), but their clinical and pathophysiologic implications have not been defined.
107 and should stimulate further studies on the pathophysiologic implications of RAGE axis in the mechan
108 rapeutics, have now clearly demonstrated the pathophysiologic importance of the complement system in
110 possible mechanism, we found that a chronic pathophysiologic insulin concentration (1 nM) caused abn
113 ory systems in isolation, ignoring the major pathophysiologic interactions between the systems in man
114 ted by the inability to accurately replicate pathophysiologic interactions of GBM cells with unique a
115 conflicting data exist on the expression and pathophysiologic involvement of the bone remodeling liga
116 ll-restricted IR/IGF-1R signaling provides a pathophysiologic link between systemic insulin resistanc
117 nal CNM-associated gene provide a definitive pathophysiologic link with these disorders, confirm that
120 d by increased RV wall thickness, were the 2 pathophysiologic markers most predictive of worse outcom
121 improve care and should be guided by direct pathophysiologic markers of arrhythmic substrate, such a
122 ASD) (PTEN-ASD), with the aim of identifying pathophysiologic markers that specifically associate wit
125 notype for psychiatric disease and suggest a pathophysiologic mechanism conferred by a CACNA1C varian
126 Disruption of such connectivity is a key pathophysiologic mechanism for ADHD, and identifying her
130 f PRDM13 in macular development, whereas the pathophysiologic mechanism of the fifth remains unknown
132 penetrant CID phenotype through a different pathophysiologic mechanism than previously described for
133 made in our understanding of the genetic and pathophysiologic mechanism underlying the development an
135 rologic consequences might reveal underlying pathophysiologic mechanisms and clinical implications of
136 riants will provide insights into underlying pathophysiologic mechanisms and facilitate the developme
137 risk factor for disease progression, but the pathophysiologic mechanisms are only incompletely unders
139 ew, we summarize the functional outcomes and pathophysiologic mechanisms attributed to progesterone t
142 ity observed in HX and indicate that various pathophysiologic mechanisms contribute to the HX phenoty
143 rcise impairment, indicating that additional pathophysiologic mechanisms contribute to the limb manif
154 date our findings and to delineate the exact pathophysiologic mechanisms linking migraine and OMCNP.
159 Recent advances in the understanding of the pathophysiologic mechanisms of strokelike episodes in ME
160 evidence suggests that age affects the main pathophysiologic mechanisms of the acute respiratory dis
162 ial) function is important to understand the pathophysiologic mechanisms that contribute to MVD and t
163 r "endotypes," which are defined by distinct pathophysiologic mechanisms that might be identified by
165 Recent progress in the understanding of pathophysiologic mechanisms underlying IgE-associated al
167 A greater understanding of the genetic and pathophysiologic mechanisms underlying the disease may l
169 Endotypes further describe the functional or pathophysiologic mechanisms underlying the patient's dis
171 g with PET may offer important insights into pathophysiologic mechanisms, diagnosis, and disease prog
172 Insulin resistance results from several pathophysiologic mechanisms, including chronic tissue in
173 h animal models suggest that several diverse pathophysiologic mechanisms, including dysregulation of
183 tolic dysfunction is widely considered a key pathophysiologic mediator of HFpEF, the prevalence of co
186 study provides insight into the mechanism of pathophysiologic occurrence of diarrhea in UC and sugges
187 c state of the diaphragm, which might be one pathophysiologic origin of ventilator-induced diaphragma
192 lygenic autoimmune disorders, as well as the pathophysiologic pathways and clinical features of monog
193 dinal investigations are needed to elucidate pathophysiologic pathways and target modifiable mechanis
194 gic agents that target specific and critical pathophysiologic pathways have been developed to better
195 enotypic difference strongly suggests unique pathophysiologic pathways involved in the pathogenesis o
197 (i.e., quantifiably infer the magnitude of a pathophysiologic perturbation), and helps explain comple
203 ally could be related to the same underlying pathophysiologic process as their renal disease, and nei
206 intestinal ischemia/reperfusion is a leading pathophysiologic process in a rat model of deep hypother
208 probable AD dementia with evidence of the AD pathophysiologic process: 24 patients with age at onset
209 d biomarkers of early Alzheimer disease (AD) pathophysiologic processes (accumulation of neocortical
210 ce: Cardiac biomarkers provide insights into pathophysiologic processes and offer an attractive strat
212 networks may reveal the impact of underlying pathophysiologic processes as assessed with cerebrospina
213 wn to have a long preclinical phase in which pathophysiologic processes develop many years, even deca
215 iques can identify biomarkers reflecting key pathophysiologic processes in depression and whether suc
216 c value of biomarkers that reflect different pathophysiologic processes in patients with type 2 diabe
217 een shown to play a crucial role in multiple pathophysiologic processes like sepsis, inflammation, va
219 of therapy that can be targeted against the pathophysiologic processes of a patient's endotype, with
220 s) are implicated in various physiologic and pathophysiologic processes such as epilepsy, sleep disor
221 ation of objective biomarkers that represent pathophysiologic processes that differ between bipolar d
222 ward a diagnostic system based on underlying pathophysiologic processes that may cut across conventio
225 y a significant role in many physiologic and pathophysiologic processes, including synaptic transmiss
232 of patient-derived GBM cells, with improved pathophysiologic properties as an experimental model.
233 reatment with trypsin; this finding may have pathophysiologic relevance by suggesting that, like beta
235 ese data provide preliminary support for the pathophysiologic relevance of neurosteroids in this cond
236 in more than 40% of breast cancers, but its pathophysiologic relevance to tumorigenesis has not been
237 lso provide insight into how physiologic and pathophysiologic remodeling differs in adipose tissue an
240 mice display a significant reduction in the pathophysiologic responses seen in asthmatic wild-type l
241 F expression resulted in amelioration of the pathophysiologic responses seen in children with allergi
242 These rapid molecular changes potentiate pathophysiologic responses throughout the body, resultin
245 2-part review, we discuss the epidemiologic, pathophysiologic, risk factors, and imaging aspects of c
246 2-part review, we discuss the epidemiologic, pathophysiologic, risk factors, and imaging aspects of c
247 Taken together, our findings established a pathophysiologic role and new function for LOXL2 in brea
250 atic cancer, revealing a dual and contextual pathophysiologic role for REG3beta during pancreatitis a
251 These observations underscore an important pathophysiologic role for severely defective metabolism
253 th a worse prognosis, and plays an important pathophysiologic role in PCa, which suggesting its poten
254 tivated by human anti-Gal IgM and may play a pathophysiologic role in pig-to-human xenotransplantatio
257 Further studies to delineate the underlying pathophysiologic role of elevated WBC across a spectrum
258 m of GN with monoclonal IgG deposits and the pathophysiologic role of granulocyte colony-stimulating
259 related to renal and heart diseases, but the pathophysiologic role of homoarginine and the genetic re
260 droplet-induced oxidative mechanisms and the pathophysiologic role of macrophages in diabetic kidneys
262 activity and, while much is known about the pathophysiologic role of NHE1 in tumor progression with
266 ed to determine whether these processes have pathophysiologic roles in delirium and whether therapies
267 in meta-inflammation, with a focus on their pathophysiologic roles in obesity, type 2 diabetes, dysl
270 part fundamentally different physiologic and pathophysiologic roles to these two endocannabinoids.
275 ncers and we provide genetic evidence of the pathophysiologic significance of FABP5 in mammary tumori
276 ture longitudinal studies should examine the pathophysiologic significance of the shift from MTL hype
277 ary atrial fibrillation), and intensity of a pathophysiologic state (i.e., quantifiably infer the mag
278 ory properties of IFNbeta that modulated the pathophysiologic state, consistent with the observed pro
279 to modulate the emergence of MDSCs in those pathophysiologic states in which these cells play an imm
280 of the tissue microenvironment in a range of pathophysiologic states, including acute and chronic res
282 emand across a wide range of physiologic and pathophysiologic states, yet, when compared with other o
286 rnate scaffold protein, SHPS-1, resulting in pathophysiologic stimulation of vascular smooth muscle c
288 tion of results from these correlational and pathophysiologic studies supports the hypothesis that ga
291 pression of Syt10 is strongly upregulated by pathophysiologic synaptic activity after kainic acid (KA
292 Excessive release of glutamate triggered by pathophysiologic synaptic activity has been put forward
296 ylinositol 4,5-bisphosphate [PI(4,5)P2], but pathophysiologic triggers for NHE1 inactivation are unkn
297 ises to transform clinical care by advancing pathophysiologic understanding and fostering novel thera
298 ion; use of biomarkers may provide important pathophysiologic understanding beyond risk prediction.
300 m)Tc-NTP 15-5) targeting proteoglycans has a pathophysiologic validity for in vivo imaging of rheumat
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