ライフサイエンスコーパス: pediatric

1 phenomenon of type 2 diabetes has emerged in pediatrics.

2 tic shock are common and, at times, fatal in pediatrics.

3 .528 T-ALL cell lines in addition to 3.7% of pediatric (6 of 160) and 5.5% of adult (9 of 163) T-ALL

4 y and Strabismus and the American Academy of Pediatrics (AAP) was convened.

5 cation of induction failure in patients with pediatric acute lymphoblastic leukemia (ALL) and to iden

6 Pediatric acute respiratory distress in tropical setting

7 y Failure patients (5%) with moderate/severe pediatric acute respiratory distress syndrome were suppo

8 Among Kilifi general pediatric admissions, 3.9% (n = 274/6968) were PCR-posit

9 were seen in outpatients aged >/=5 years and pediatric admissions.

10 t Master Protocol and International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P107

11 Care Medicine and American Heart Association/Pediatric Advanced Life Support sanctioned recommendatio

12 linically stable children with CF across the pediatric age range (0.2-21.1 yr).

13 cal, and laboratory data for newly diagnosed pediatric (age <15 years) TB cases reported to the US Na

14 ntion was not associated with a reduction in pediatric AHT hospitalization rates but was associated w

15 ial prophylaxis during induction therapy for pediatric ALL and the first to include a broad-spectrum

16 ndrome (CRS) and preinfusion tumor burden in pediatric ALL.

17 Our recent cluster of CMV retinitis in pediatric allogeneic HSCT patients may suggest a rise in

18 , as a surrogate for NETs in 103 consecutive pediatric allogeneic transplant recipients at day 0, +14

19 We sought to comprehensively profile pediatric AML microRNA (miRNA) samples to identify dysre

20 ored targeted therapies for the treatment of pediatric AML.

21 sequencing on specimens from 99 patients (75 pediatric and 24 adult).

22 he association between DGF and graft loss in pediatric and adolescent deceased donor kidney transplan

23 t that A3A is highly expressed in subsets of pediatric and adult acute myelogenous leukemia (AML).

24 -wide association analyses were performed in pediatric and adult asthma cases and control subjects wi

25 on-based estimates suggest the prevalence of pediatric and adult disease may be similar.

26 hieved MRD negativity is substantial in both pediatric and adult patients with ALL.

27 e tests had similar levels of performance in pediatric and adult patients.

28 rden of Respiratory Syncytial Virus (RSV) in pediatric and elderly populations is well recognized.

29 is a crucial process for the preparation of pediatric and geriatric formulations as well as fast dis

30 aphy for measurement of hepatic stiffness in pediatric and young adult patients suspected of having l

31 stologic response and event-free survival in pediatric and young adult patients with osteosarcoma (OS

32 ons in 3 arms of patient populations (adult, pediatric, and mixed).

33 omplementary features of these treatments in pediatric anxiety disorders.

34 ifferentiating perforated from nonperforated pediatric appendicitis and to investigate the associatio

35 ance (MR) imaging for the imaging work-up of pediatric appendicitis.

36 hly specific but nonsensitive for perforated pediatric appendicitis.

37 ay platforms applied on a well-characterized pediatric asthma cohort.

38 ed Outcomes Measurement Information System's Pediatric Asthma Impact Scale.

39 er (OCD) and tic disorders, a concept termed pediatric autoimmune neuropsychiatric disorders associat

40 of HTS improves upon FC for MRD detection in pediatric B-ALL by identifying a novel subset of patient

41 Until recently, 20% to 30% of pediatric B-cell precursor acute lymphoblastic leukemia

42 A pediatric-based brief behavioral intervention for anxiet

43 mechanisms underlying epileptogenesis after pediatric brain injury, and provide evidence of IL-1 sig

44 post-traumatic epilepsy in a mouse model of pediatric brain injury, and to evaluate the role of inte

45 Reference databases of pediatric brain metabolism are uncommon, because local b

46 at allow for accurate prediction of regional pediatric brain metabolism.

47 sity (SI) of the dentate nucleus (DN) of the pediatric brain on nonenhanced T1-weighted magnetic reso

48 hat a mouse model of traumatic injury to the pediatric brain reproduces many neuropathological and se

49 s to transcriptional disruptors in the fatal pediatric brain tumor, diffuse intrinsic pontine glioma

50 for providing optimal surgical management of pediatric brain tumors.

51 yncytial virus (RSV) is the leading cause of pediatric bronchiolitis and hospitalizations.

52 mpling methods are flawed, particularly in a pediatric bronchiolitis setting.

53 d in malignant rhabdoid tumor, an aggressive pediatric cancer characterized by biallelic inactivation

54 These differences may explain why pediatric cancer patients have a higher risk of developi

55 Pediatric cancers are generally characterized by low mut

56 ith cyclins and has been linked to adult and pediatric cancers.

57 Two cohorts were recruited through the Pediatric Cardiac Genomics Consortium: 355 CTD trios and

58 ere may serve as a promising therapeutic for pediatric cardiac regeneration.

59 e likely to practice in academic centers, be pediatric cardiologists, and have a noninvasive subspeci

60 he ACPC sought to develop QMs for ambulatory pediatric cardiology practice.

61 logy, pediatric endocrinology, and adult and pediatric cardiology used the patient-centered Strength

62 Although adult and pediatric cardiomyopathies have similar morphological an

63 zed the epidemiology, cause, and outcomes of pediatric cardiomyopathies.

64 (Pediatric Cardiomyopathy Registry [PCMR]; NCT00005391).

65 onal Heart, Lung, and Blood Institute-funded Pediatric Cardiomyopathy Registry.

66 QR, 0.05-0.34] to 0.07 [IQR, 0.01-0.23]) for pediatric care.

67 In the first reported pediatric case series of virologically confirmed Zika vi

68 ears) with similar prevalence in both sexes; pediatric cases (</=16 years of age) accounted for 10.1%

69 were conspicuously absent from virtually all pediatric cases.

70 ed for regular and long-term follow-up after pediatric cataract surgery.

71 welling is a major predictor of mortality in pediatric cerebral malaria (CM).

72 h favorable neurological outcome, defined as Pediatric Cerebral Performance Categories 1 to 3 or no w

73 w of the high frequency of gene mutations in pediatric cerebrospinal AVFs, and show the predominance

74 st-effectiveness of 4 strategies: no choice, pediatric choice, adult choice, or choice for both age g

75 te the efficacy of nontransplant surgery for pediatric cholestasis, 58 clinically diagnosed children,

76 Clinical status at last pediatric clinic visit prior to transfer was described.

77 vectored RSV vaccine candidate suitable for pediatric clinical evaluation.IMPORTANCE RSV and HPIV3 a

78 adults, our data warrant the development of pediatric clinical trials for this particularly vulnerab

79 al hypertension (PAH) is hampered by lack of pediatric clinical trials.

80 Among pediatric conditions, more than 75% were highly regional

81 To use data from the Pediatric Contact Dermatitis Registry to elucidate the a

82 nt trios, and 406 CTD cases (n=406) and 2976 pediatric controls.

83 survival to hospital discharge was lower for pediatric CPR events occurring at night than for CPR eve

84 anish language medical interpretation during pediatric critical care family meetings.

85 gestation and <19 years old in Collaborative Pediatric Critical Care Research Network intensive care

86 Twenty-five pediatric critical care units in the United States, the

87 All children admitted to the pediatric critical care units on designated study days (

88 utine utilization of the current concepts in pediatric CT optimization.

89 Workshop in Budapest, 2015 (www.haenet.hu), pediatric data were presented and discussed and a consen

90 study was to determine associations between pediatric delirium and modifiable risk factors such as b

91 However, the epidemiology and outcomes of pediatric delirium are not well-characterized.

92 for delirium using the Cornell Assessment of Pediatric Delirium by the bedside nurse.

93 examined for general dentists, endodontists, pediatric dentists, oral surgeons, orthodontists, and pe

94 An expert panel in psoriasis, pediatric dermatology, pediatric rheumatology, pediatric

95 Although a leading cause of pediatric diarrhea, human astroviruses are among the lea

96 eline (18)F-FDG PET voxel characteristics in pediatric diffuse intrinsic pontine glioma (DIPG) and to

97 lar rhabdomyosarcoma (ARMS) is a devastating pediatric disease driven by expression of the oncogenic

98 Tuberous sclerosis complex (TSC) is a pediatric disorder of dysregulated growth and differenti

99 uestion arose from our observation that most pediatric donors carry a KDPI over 35 and have therefore

100 ntation following KAS, including: (i) use of pediatric donors, (ii) use of Public Health System (PHS)

101 ors appears to be even worse when applied to pediatric donors.

102 is retrospective analysis of the prospective Pediatric Emergency Care Applied Research Network (PECAR

103 ic rheumatology, pediatric gastroenterology, pediatric endocrinology, and adult and pediatric cardiol

104 on several of the most catastrophic forms of pediatric epilepsy.

105 ically defined adult T-ALL is similar to the pediatric equivalent, with high rates of mutations in fa

106 We sought to identify risk factors for pediatric extubation failure, with specific attention to

107 pating US hospitals, including free-standing pediatric facilities, children's hospitals, specialty ce

108 research is needed to develop more effective pediatric fall prevention strategies tailored to patient

109 sed 4-item Little Schmidy, the LS4, predicts pediatric falls when administered every day and night sh

110 The pediatric-focused international consensus for the diagno

111 th those endorsed by the American Academy of Pediatrics for the general pediatric patient but with ad

112 be shared to support progress in developing pediatric formulations for other diseases, including tub

113 diatric dermatology, pediatric rheumatology, pediatric gastroenterology, pediatric endocrinology, and

114 refractory GFCS and JOAG in a single-surgeon pediatric glaucoma practice who underwent illuminated mi

115 The majority of pediatric gliomas present as benign, slow-growing lesion

116 al accounting system data versus data in the Pediatric Health Information System (PHIS).

117 We reviewed data from the Pediatric Health Information System database from 2004 t

118 ere used to identify study subjects from the Pediatric Health Information System database, and chart

119 Within the Pediatric Health Information System for freestanding ped

120 n 25 US children's hospitals included in the Pediatric Health Information System.

121 elationship between socioeconomic status and pediatric health outcomes for ACSCs.

122 th/National Heart, Lung, and Blood Institute Pediatric Heart Network Single Ventricle Reconstruction

123 tus and Ventricular Performance After Fontan-Pediatric Heart Network; NCT00132782).

124 The use of induction therapy in pediatric heart transplantation has increased.

125 an Sharing database was queried for isolated pediatric heart transplants from January 1, 1994, to Dec

126 hat both models are closely related to human pediatric HGG as compared with adult HGG.

127 ring pregnancy to achieve the elimination of pediatric HIV infections.

128 th antiretroviral therapy (ART) to eliminate pediatric HIV-1 infection will require the characterizat

129 Combining data from the Pediatric HIV/AIDS Cohort Study (PHACS) Adolescent Maste

130 t interim assessment and end of treatment in pediatric Hodgkin lymphoma (HL) are limited.

131 pothesis that the availability of definitive pediatric hospital care is significantly more limited th

132 d patient-level administration data from the Pediatric Hospital Information Systems (PHIS) database,

133 Pediatric hospital inpatients <25 years of age.

134 At a freestanding pediatric hospital, we retrospectively assessed anti-inf

135 ring the 2014 EV-D68 epidemic, high rates of pediatric hospitalizations and ED visits were observed.

136 en January 2000 and May 2014 at six academic pediatric hospitals in North America was performed.

137 The capacity of pediatric hospitals to provide treatment to large number

138 c Health Information System for freestanding pediatric hospitals, annual risk-adjusted mortality rate

139 th interventions are increasingly popular in pediatrics; however, it is unclear how effective these i

140 screening protocol to diagnose retinitis in pediatric HSCT patients in the early, often asymptomatic

141 oninferior to iHT performed by therapists in pediatric IBS or FAP(S).

142 Pediatric inflammatory bowel disease (pIBD) is a chronic

143 IFITM3 has not been evaluated in pediatric influenza.

144 group is delineated, and the role of using "pediatric-inspired" regimens in older adults considered.

145 T techniques, based on a survey of 19 PET/CT pediatric institutions in North America.

146 Purpose To propose and validate a modified pediatric intracerebral hemorrhage (PICH) (mPICH) score

147 S) implantation followed by cross-linking in pediatric keratoconus patients.

148 ective as the conventional protocol to treat pediatric keratoconus.

149 ally significant impact on graft survival of pediatric kidney transplants (P < 0.001).

150 Based on an analysis of 542 pediatric kidney transplants recorded by the UK Transpla

151 uding the allocation of fewer deceased donor pediatric kidneys to children and stagnation in pediatri

152 stiffness to adult baseline values to detect pediatric liver mechanical abnormalities may not allow d

153 ho died or were delisted received a median 1 pediatric liver offer and waited a median of 33 days.

154 Comparing pediatric liver stiffness to adult baseline values to de

155 Among pediatric liver transplant candidates in the US, childre

156 Pediatric liver transplant recipients arguably have the

157 These pediatric low-grade gliomas (LGGs) are fundamentally dif

158 Pediatric low-grade gliomas (PLGGs) are commonly associa

159 iremia and risk factors for CMV infection in pediatric LT recipients managed with ganciclovir-based p

160 s (AYAs) (15-39 years) compared with that of pediatric (<15 years) and older adult (>/=40 years) pati

161 ith BOS, and compared them against 13 stable pediatric LTxR at 1, 6, and 12 months after LTx.

162 Better estimates of pediatric MDR-TB burden in the United States are needed

163 To ascertain potential underestimation of pediatric MDR-TB, we surveyed high-burden states for cli

164 ttle is known about the genomic landscape of pediatric MDS.

165 Pediatric medical and surgical inpatient units of an aca

166 n, if any, to use to prevent the headache of pediatric migraine has not been established.

167 The most common pediatric mitochondrial disease is Leigh syndrome, an ep

168 Patient-derived xenografts (PDX) of pediatric mixed-lineage leukemia gene (MLL)-rearranged A

169 SLIT-tablets was considered similar between pediatric (n = 795) and adult (n = 2299) data pools, wit

170 for elucidating the developmental origins of pediatric neoplasms.

171 Pediatrics, nontacrolimus/mycophenolate regimens, and no

172 amin B9 (folate) in infant formula and adult/pediatric nutritional products is presented.

173 nt subtypes, and clinical characteristics of pediatric nystagmus diagnosed over a 30-year period.

174 s that have transformed our understanding of pediatric ocular motor disease at the prenuclear and inf

175 o 129 patient-parent dyads of hospital-based pediatric oncology ambulatory clinics and inpatient unit

176 A perceived barrier, especially for pediatric oncology patients, is the notion that patients

177 After pediatric onset MS (POMS) diagnosis, age at onset younge

178 with support of the American Association for Pediatric Ophthalmology and Strabismus and the American

179 Five patients in an academic pediatric ophthalmology and strabismus practice with a c

180 3 guidelines of the American Association for Pediatric Ophthalmology and Strabismus.

181 ed to become a standard component of care in pediatric ophthalmology.

182 The daily pSOFA scores and additional pediatric organ dysfunction scores were compared.

183 mal models lead to regional neuronal losses, pediatric OSA patients may also be affected.

184 of the US population and the rising rates of pediatric overweight/obesity, we sought to examine the a

185 Pediatric PAH patients have increased apparent ascending

186 ormance and impacts systemic hemodynamics in pediatric PAH.

187 erican Academy of Pediatrics for the general pediatric patient but with added attention to signs and

188 pse or cardiopulmonary arrest in an adult or pediatric patient who has a ventricular assist device or

189 ommodation states) reported they cared for a pediatric patient whose family requested continuation of

190 comfortable handling a situation in which a pediatric patient's family requested care be continued a

191 nstitutional review board-approved study, 41 pediatric patients (age range, 3-17 years) who were imag

192 ient clinics throughout the United States on pediatric patients (ages 0-18 years).

193 graft survival and functional outcomes in HS pediatric patients as nonsensitized patients receiving a

194 Data from all North American pediatric patients in the Extracorporeal Life Support In

195 Automatic inclusion of pediatric patients is appropriate in early-phase trials

196 yngeal samples (n = 300) were collected from pediatric patients presenting to the emergency departmen

197 Materials and Methods Consecutive pediatric patients scheduled to undergo liver biopsy wer

198 Pediatric patients should always carry a C1-INH-HAE info

199 and unenhanced MR imaging were performed in pediatric patients suspected of having appendicitis was

200 Consecutive adult and pediatric patients tested at an academic institution bet

201 d to determine whether specific subgroups of pediatric patients undergoing cardiopulmonary bypass wou

202 ere reviewed to determine the rates at which pediatric patients were identified as having a body mass

203 The authors evaluated 46 pediatric patients who had undergone at least three GBCA

204 arch of the radiology database revealed 2180 pediatric patients who had undergone imaging for suspect

205 ociation of race/ethnicity with mortality in pediatric patients who receive extracorporeal life suppo

206 In pediatric patients with acute appendicitis undergoing ap

207 uencies of positive sIgE levels were seen in pediatric patients with AD (P < .0001).

208 We report a cluster of 5 pediatric patients with CMV retinitis diagnosed in a 12-

209 In pediatric patients with dilated cardiomyopathy, compared

210 Peripheral B and T cells are altered in pediatric patients with early AD, but T cells predominat

211 a prospective study of long-term outcomes of pediatric patients with IBD (NCT00606346), from May 31,

212 for the development of malignancy or HLH in pediatric patients with IBD.

213 and, less accurately, mild liver fibrosis in pediatric patients with nonalcoholic fatty liver disease

214 f genes that are differentially expressed in pediatric patients with pneumonia syndrome attributable

215 lated genes correlated with the prognosis of pediatric patients with pre-B-ALL, and fasting effective

216 inal microvascular morphology was evident in pediatric patients with T1D after one-year's poor glycem

217 these disease processes to optimize care for pediatric patients with these conditions.

218 l mucosa are up-regulated in treatment-naive pediatric patients with UC compared with patients with C

219 encing and analyzed the transcriptomes of 68 pediatric patients with well-characterized clinical phen

220 d growth of the supply of surgeons who treat pediatric patients-including general pediatric surgeon a

221 unwanted side effects, and restricted use in pediatric patients.

222 rkup for inflammatory bowel disease (IBD) in pediatric patients.

223 rformance of Septicyte Lab in critically ill pediatric patients.

224 ine exposure, to mitigate iatrogenic harm in pediatric patients.

225 lso results in a high diagnostic accuracy in pediatric patients.

226 shift and 10 missense changes) in GNB1 in 16 pediatric patients.

227 sources, has been modeled for adults but not pediatric patients.

228 urvival outcomes compared with those seen in pediatric patients.

229 nt of uncomplicated P. falciparum malaria in pediatric patients.

230 analysis was conducted, pooling data from 3 pediatric peanut OIT trials, comprising the largest anal

231 We describe the variability in pediatric PET/CT techniques, based on a survey of 19 PET

232 A function (reservoir, conduit, and pump) in pediatric PH.

233 may be an important diagnostic indicator in pediatric pneumonia.

234 clinical usefulness of genetic testing in a pediatric population with inherited retinal disease (IRD

235 By characterizing a pediatric population with LVNC, we sought to determine t

236 development of glucose intolerance in the CF pediatric population, and to CFRD, later in life.

237 In a large pediatric population, the complexity of IgE sensitizatio

238 gs and for the shorter MDR-TB regimen in the pediatric population.

239 y in a specific disease that spans adult and pediatric populations.

240 ghting the need to conduct vaccine trials in pediatric populations.

241 nuary 2015 and April 2016 in a network of 31 pediatric primary care practices in Pennsylvania and New

242 ronutrients (MMN) are commonly prescribed in pediatric primary healthcare in sub-Saharan Africa to im

243 k the long-term risks of systemic agents for pediatric psoriasis.

244 t of evidence-based treatment guidelines for pediatric pulmonary arterial hypertension (PAH) is hampe

245 RATIONALE: Pediatric pulmonary hypertension (PH) is a heterogeneous

246 children from the Dutch National Network for Pediatric Pulmonary Hypertension.

247 alth-related quality of life measured by the Pediatric Quality of Life 4.0, and parental resource emp

248 13.1; 95% CI, 10.7 to 15.6; P<0.001), on the Pediatric Quality of Life Inventory (difference, 21.9; 9

249 or Children (IVI-C), and (3) HR QoL with the Pediatric Quality of Life Inventory (PedsQL) version 4.0

250 FIF is a pediatric rarity.

251 Kidney transplants performed for pediatric recipients (age, <18 years) in the United King

252 ore been rendered relatively inaccessible to pediatric recipients under KAS.

253 We describe the results of 11 ABOi pediatric renal transplant recipients in the 2 largest c

254 st and second leading viral causes of severe pediatric respiratory disease worldwide.

255 SV and HPIV1 are major viral causes of acute pediatric respiratory illness for which no vaccines or s

256 enza virus type 1 (HPIV1) also causes severe pediatric respiratory illness, especially croup.

257 omography and OCTA are gaining popularity in pediatric retinal imaging.

258 t panel in psoriasis, pediatric dermatology, pediatric rheumatology, pediatric gastroenterology, pedi

259 refore an attractive antigen candidate for a pediatric RSV subunit vaccine.

260 suggests that CTT mitigates infarct risk in pediatric SCA by relieving cerebral metabolic stress at

261 6 might be a potential target for therapy of pediatric SE.

262 The inclusion criteria were (1) pediatric seizure onset with ongoing seizure activity in

263 ALE: We previously derived and validated the Pediatric Sepsis Biomarker Risk Model (PERSEVERE) to est

264 have utility in early risk stratification of pediatric sepsis.

265 lines for hemodynamic support of newborn and pediatric septic shock.

266 l use of whole-exome sequencing (WES) in the pediatric setting requires an understanding of who shoul

267 ch preclinical findings are relevant for the pediatric setting.

268 rather than adverse role for neutrophils in pediatric severe asthma pathophysiology.

269 atching, exclusive use of balanced fluids in pediatric severe sepsis patients for the first 72 hours

270 trophils and the IL-17A pathway in mediating pediatric severe therapy-resistant asthma (STRA).

271 In 2005, the European Pediatric Soft Tissue Sarcoma Study Group (EpSSG) propos

272 Because of the limited number of pediatric studies published on these topics, the strengt

273 These two mouse models relevant to human pediatric supratentorial HGG propose an important role o

274 ur estimates indicate considerable potential pediatric surge capacity by using combined strategic ini

275 o treat pediatric patients-including general pediatric surgeon and focused subspecialties.

276 To describe the future supply and demand for pediatric surgeons using a physician supply model to det

277 model to determine what the future supply of pediatric surgeons will be over the next decade and a ha

278 The supply of all pediatric surgeons will grow relatively rapidly through

279 d female neonate presented to the outpatient pediatric surgery clinic for evaluation of a possible pr

280 The rate of entry into pediatric surgery will continue to exceed population gro

281 surgery, general surgery, vascular surgery, pediatric surgery, obstetrics/gynecology, ophthalmology,

282 Adequately powered studies in the pediatric surgical population are scarce, and it is uncl

283 rican PICUs that participated in the Virtual Pediatric Systems, LLC (VPS, LLC, Los Angeles, CA).

284 al therapies and overcoming GC resistance in pediatric T-ALL patients.

285 al injury (neuromarkers) and inflammation in pediatric TBM and their association with outcome.

286 survivors diagnosed before age 21 years from pediatric tertiary hospitals in the United States and Ca

287 nce to controls receiving corticosteroids in pediatric transplant recipients which reported growth as

288 Here we explore early trends in pediatric transplantation following KAS, including: (i)

289 Over the last decade 65% of our pediatric transplants were SLT.

290 as 100% in the ABOi and 98% in 50 compatible pediatric transplants.

291 arm legislation is associated with decreased pediatric, unintentional, suicide, and overall FFR, but

292 should be further developed as an intranasal pediatric vaccine.IMPORTANCE RSV and HPIV1 are major vir

293 The incidence of pediatric venous thromboembolism (VTE) has been increasi

294 To adapt and validate a pediatric version of the SOFA score (pSOFA) in criticall

295 , and RIMS1 as novel susceptibility loci for pediatric VTE and warrant future functional studies to u

296 present a GWAS in 212 nuclear families with pediatric VTE followed by targeted next-generation seque

297 Management of pediatric VTE is a complex undertaking, considering that

298 iatric kidneys to children and stagnation in pediatric wait times.

299 als, and general acute care hospitals with a pediatric wing.

300 ificantly delayed tumor growth in all rodent pediatric xenograft models and extended animal survival