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3 queezes its nucleus through adjacent tissue, penetrates a basement membrane, or enters a small blood
5 on of a pre-SufI signal peptide hairpin that penetrates about halfway across the membrane bilayer.
6 H4-L1 exhibits antimicrobial and potent cell-penetrating activities for a wide variety of cargo inclu
7 we found that PepB2 had more efficient cell-penetrating activity than several other well-known CPPs
9 implication other SBFS species) from a plant-penetrating ancestor to a non-invasive ectophyte, displa
10 a use a unique undulating flat-wave shape to penetrate and propel themselves through host tissues.
12 served 72-residue hydrophobic hairpin, which penetrates and stabilizes the LD Oleosin is synthesized
13 l adhesion motifs, structural peptides, cell-penetrating and tumor-homing peptides, antimicrobial pep
16 sed to follow the adsorption of the membrane-penetrating antimicrobial peptide Temporin L in differen
18 h the epidermis and dermis and that the skin-penetrating aptamer retains its biologically active conf
20 ies in cats, as well as surface arteries and penetrating arterioles in rat visual cortex (where orien
21 gs in SIDER database having the potential to penetrate BBB, which could serve as start point for CNS
22 to both small compounds and macro-molecules penetrating BBB through various mechanisms besides passi
23 that COR15A interacts with the membranes and penetrates below the headgroup region into the upper par
24 showed that the long anionic HCDR3 of PGT145 penetrated between glycans at the trimer 3-fold axis, to
25 he corneas of IL-1R (-/-) or TLR5 (-/-) mice penetrated beyond the epithelial surface only if the cor
26 n reflection further substantiates that PlyC penetrates bilayers above a PS threshold concentration.
28 microPET/CT imaging indicate its ability to penetrate brain and label parenchymal plaques in transge
29 ple of 112 Vietnam War veterans who suffered penetrating brain injury and 33 healthy controls who als
32 ss changes in the lower part of the MT film, penetrated by the acoustic wave, is able to detect a pro
34 demonstrated that six of the 24 amino acids penetrate cells through a particular gate represented by
39 ti-TNFalpha therapy were less likely to have penetrating complications (hazard ratio [HR] 0.30, 95% C
42 closure of the PVS around surface as well as penetrating cortical arteries and veins lasting several
43 rring that involved the subpial glial plate, penetrating cortical blood vessels, grey-white matter ju
45 il, uL23(tail), which is a beta-hairpin that penetrates deep into the core of the large ribosomal sub
48 Membrane-ordering effects are greater and penetrate deeper into membranes when FP1 and FP2 act in
49 velength swept light source that can readily penetrate deeper into the tissue because of the longer w
50 increased, allowing submerged vegetation to penetrate deeper, and the habitat suitable for fish and
52 dimer to organize into two long helices that penetrate deeply into the regulatory RCK domains, thus c
55 apsulated EtNBS nanoparticles are capable of penetrating deeply into the hypoxic and acidic cores of
58 open structure, where water molecules could penetrate easier within the microparticles, substantiall
59 RNA-directed oligonucleotides with such skin-penetrating epidermal agents will drive the development
60 A0716 allows S. lycopersicum pollen tubes to penetrate farther into the pistil in HT suppressed plant
61 Pentacam HR; Oculus, Wetzlar, Germany) after penetrating femtosecond laser-assisted keratotomy (pFLAK
63 re of the right lateral pterygoid plate by a penetrating foreign body (wooden twig) in an adult male
64 In addition, analysis for rare and highly penetrate functional variants revealed four novel varian
65 case study in Germany indicates that plague penetrated further into Europe through the local trade r
66 ne glycol (PEG) molecules (PBAE-PEG) rapidly penetrate healthy brain parenchyma and orthotopic brain
67 opment, as evidenced by polluted clouds that penetrate higher above the top of the surface mixed laye
72 nt above 80 mg/dL (P < 0.0001), and suffer a penetrating injury (P < 0.0001) compared with nonrecidiv
73 race, and elevated blood alcohol content and penetrating injury are associated with trauma recidivism
74 re more likely to be injured by a blunt than penetrating injury mechanism (91.4%) compared with those
83 proximately half of the DNA-bound Rb(+) ions penetrate into the minor groove of the DNA and half adso
85 aser desorption of hair strands was shown to penetrate into the strand cortex, allowing direct measur
86 ts show that both sets of AuNPs could easily penetrate into the tumors but their uptake and retention
88 e showed that endothelial cords aggressively penetrated into microtumors and remained non-circulatory
91 , we showed that the protein fragment hardly penetrated into the lungs following subcutaneous injecti
92 0 mg/L concentrations revealed that TiO2 NPs penetrated into the plant root and resulted in Ti accumu
95 uantum interference device to image vortices penetrating into a superconducting Pb film at rates of t
98 to epicardial layers, BODIPY was capable of penetrating into the myocardium, resulting in a transmur
99 that prevented the acid-foulant mixture from penetrating into the porous support during acid treatmen
100 r that slows the growth of lithium dendrites penetrating into the separator is produced by sandwichin
101 tic modulating effect on the solar radiation penetrating into the subsurface layers, which induces di
104 included post-cataract surgery (n = 6), post-penetrating keratoplasty (n = 2), and post-trabeculectom
105 e likely to perforate or require therapeutic penetrating keratoplasty (odds ratio: 6.27; 95% CI: 2.73
106 djusted hazard ratio [HR], 1.56; P < 0.001), penetrating keratoplasty (PK) (adjusted HR, 1.12 vs. ALK
107 tomated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PK) for Fuchs endothelial dyst
110 nking (CXL) and conventional management with penetrating keratoplasty (PKP) when indicated in managin
111 utcomes of patients that underwent pediatric penetrating keratoplasty (PPK) for herpes simplex virus
113 nts diagnosed with microbial keratitis after penetrating keratoplasty at the National Taiwan Universi
114 ears of age or younger who underwent primary penetrating keratoplasty at Wills Eye Hospital Cornea Se
115 creased hazard of perforation or therapeutic penetrating keratoplasty compared with placebo after con
119 red thirty-nine eyes (96 corneal grafts post penetrating keratoplasty or Descemet stripping automated
122 and other anterior segment-related (eg, post-penetrating keratoplasty), bleb-associated, glaucoma dra
123 d FECD, defined by a need for endothelial or penetrating keratoplasty, has not been investigated.
124 ieving visual results comparable to those of penetrating keratoplasty, while sparing a healthy endoth
128 emonstrated that MDMs and DCs are capable of penetrating large-pore membranes but not small-pore memb
130 f vision, namely late vision, is cognitively penetrated mainly through the effects of cognitively dri
132 s, both in the presence and absence of NTRs, penetrate more readily into the FG-meshwork compared to
133 uenced BODIPY distribution, with fluorophore penetrating more readily into atria than ventricles.
134 A peptide drug is fused with a short cell-penetrating motif and converted into a conformationally
135 ult, these "brain penetrating nanoparticles" penetrate much deeper into brain tumor tissue compared t
136 -PEG blended nanocomplexes (DNA-loaded brain-penetrating nanocomplexes, or DNA-BPN) was uniform throu
137 s a blood-brain barrier-/blood-tumor barrier-penetrating nanoconjugate to deliver small interfering (
140 hanced when cisplatin was delivered in brain penetrating nanoparticles (median survival not reached;
144 grading of these distinctive neoplasms.Deep penetrating nevi (DPN) are unusual melanocytic neoplasms
146 rs are emerging as a promising technology to penetrate new industrial and medical applications from t
148 ss-penetrating polymers push the more easily penetrating ones into nanosize channels in excess of the
152 entified as an orally bioavailable and brain penetrating PDE1B enzyme inhibitor with potent memory-en
153 the current study, we have developed a cell-penetrating peptide (CPP) conjugate of the HIV TAT prote
156 tion, Yan et al validated the use of a tumor-penetrating peptide and thermosensitive doxorubicin (DOX
157 from the paper "Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drug
158 show that targeting of p32 with linTT1 tumor-penetrating peptide improves tumor selectivity and antit
159 iu and colleagues show that the cyclic tumor-penetrating peptide iRGD, reported to be capable of enha
163 oparticle surface modification with the cell penetrating peptide TAT facilitates brain-specific deliv
164 modification of nanoparticles with the cell-penetrating peptide TAT increases their biophysical asso
166 ting transcriptional activator (TAT), a cell-penetrating peptide, is extensively used for facilitatin
168 for PCI by conjugating the chlorin to a cell penetrating peptide, using bioorthogonal ligation chemis
169 arrestin signaling process with a novel cell-penetrating peptide, we were able to inhibit both thromb
170 e the delivery of cargoes into cells by cell-penetrating peptides (CPPs) and the bactericidal activit
178 pecific GE11 peptide), acid-activatable cell-penetrating peptides (i.e., TH peptide), and imaging pro
182 has a predicted structural analogy with cell-penetrating peptides and that both the entire protein an
184 enhanced by the action of targeting and cell-penetrating peptides attached to the calcium silicate sh
187 These attributes suggest that related, cell-penetrating peptides should effectively inhibit active G
188 t miRNA function using vehicles such as cell penetrating peptides, spherical nucleic acids, deformabl
195 ere, we introduce a technology based on cell-penetrating poly(disulfide)s that solves this problem: w
196 on is based on the idea that relatively less-penetrating polymers push the more easily penetrating on
197 of this transition by designing smart, cell-penetrating polymers that undergo acid-activated endosom
198 d with transposon-containing plasmid DNA, it penetrates prokaryotic or eukaryotic cells and integrate
201 edrock scarps, mapped using LiDAR and ground penetrating radar, and compare these rates to those infe
202 ent high-resolution maps, acquired using ice-penetrating radar, of the bed topography across parts of
203 te of spontaneous emission of characteristic penetrating radiation and the ease of its shielding.
204 ly packed soils highlighted the impacts of a penetrating root system in changing the surrounding poro
205 CKGROUND DATA: IMA techniques have failed to penetrate routine practice due to limitations, including
207 imaging suggests positively charged NPs may penetrate skin to a lesser extent and thereby are less a
208 mAbs that are bound to a tumor surface will penetrate slowly compared with the half-lives of (211)At
209 Mutation in COP1 causes severe defects in penetrating soil, due to decreased level of EIN3, a mast
213 cerebral ischemia demands a carrier that can penetrate the blood-brain barrier (BBB) and subsequently
214 , an anti-huTNF-alpha antibody that does not penetrate the blood-brain barrier and prevents arthritis
217 s reduce survival of aquatic zooplankton and penetrate the blood-to-brain barrier in fish and cause b
219 ll-penetrating peptides - RB1 and RB3 - that penetrate the brain and, in the micromolar range, inhibi
220 opam, a peripheral D1R agonist that does not penetrate the brain, dramatically suppressed tumor growt
228 nd ETFDH mutants, most appressoria failed to penetrate the host epidermis due to low turgor pressure.
229 omplete loss of conidiation and inability to penetrate the host surface by mycelia-formed appressoriu
230 nal motility and to enable the spirochete to penetrate the host, traverse tissue barriers, disseminat
231 d by streams of cold gas, which were able to penetrate the hot halo gas until they were cut off by sh
232 ile thermal hepatic injury, neutrophils also penetrate the injury site and perform the critical tasks
233 that small particle aerosols of virus would penetrate the lower respiratory tract and blanket alveol
234 wed that NAC and acetic acid at pH < pKa can penetrate the matrix and eventually kill 100% of the bac
235 f the C-terminal four-helix bundle appear to penetrate the membrane bilayer, stabilizing ExoU-membran
237 Is in E. coli cells including the ability to penetrate the outer membrane, improved inhibition of eff
244 extracellular environment, allowing water to penetrate the space behind the selectivity filter while
245 al inflammatory rim, for IRE, the infiltrate penetrated the ablation zone, largely along persistently
246 l tip in vertically-oriented phages that had penetrated the cell wall, capturing the final stage of a
248 the treatment of dental caries that has not penetrated the tooth pulp, maintenance of as much unaffe
249 e tyrosine kinase inhibitor erlotinib poorly penetrates the blood-brain barrier (BBB) because of effl
250 we found that pterostilbene, a compound that penetrates the blood-brain barrier, could suppress brain
253 ective in the same tumor type not because it penetrates the CNS degree better, but because it scaveng
255 lyomavirus simian virus 40 (SV40), the virus penetrates the endoplasmic reticulum (ER) membrane to re
256 robe how the non-enveloped polyomavirus SV40 penetrates the endoplasmic reticulum (ER) membrane to re
260 model showing that Pg rapidly adheres to and penetrates the zebrafish vascular endothelium causing a
262 ssociated with nerve fiber branching points, penetrating the basement membrane and reaching into the
264 infection induces the formation of channels penetrating the compacted layer of cellular chromatin an
266 3CR1(-/-) mice the numbers of S. Typhimurium penetrating the epithelium were significantly higher.
268 whereby the particles behave as projectiles penetrating the oil droplets to depths varying from appr
269 genous cytoplasmic alphaS by either directly penetrating the plasma membrane or via endocytosis-media
271 depletion, removing 6% of biota per pass and penetrating the seabed on average down to 2.4 cm, wherea
272 terface would entail communicative knowledge penetrating the sensorimotor system and directly affecti
277 embrane-impermeant fluorescent dyes likewise penetrate through P2X receptors to label a subset of RGC
280 e was uniform and neurons and neurofilaments penetrated through the mesh by 3 mo postimplantation.
281 act with the other intense laser pulse which penetrates through the second foil due to relativistical
284 A2157 allows S. lycopersicum pollen tubes to penetrate to the ovary and produce hybrids that, otherwi
285 (no signals scattering and only mean values penetrating to the cloak's interior), the sensitivity of
286 underwent 40- or 64-row multidetector CT for penetrating torso trauma below the diaphragm and had sur
287 D] age, 47 [19] years) and 324 patients with penetrating trauma (mean [SD] age, 35 [15] years), the r
290 ted of 90 patients, including both blunt and penetrating trauma victims with a median injury severity
293 e same in patients who experienced blunt and penetrating trauma, the independent risk factors for VTE
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