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1 oligomeric states, KcsA (tetramer) and CorA (pentamer).
2 tramer formation, as an E120A mutant forms a pentamer.
3 r C) relative to the first nucleotide of the pentamer.
4 on when compared with the isolated terminase pentamer.
5 ognition in the context of the phospholamban pentamer.
6 GFP or red autofluorescent protein and a GFP pentamer.
7 ins recapitulate the structure of the native pentamer.
8 elly-roll core) associate with a neighboring pentamer.
9 n base involving clockwise untwisting of the pentamer.
10 In solution, the protein functions as a pentamer.
11 he gH/gL/UL128/UL130/UL131 (gH/gL/UL128-131) pentamer.
12 sts at least one alpha1-alpha1 interface per pentamer.
13 erized soluble forms of gH/gL, gH/gL/gO, and Pentamer.
14 351 in gH/gL/gO and with UL128-Cys162 in the Pentamer.
15 the same as well as additional sites on the pentamer.
16 suggest that it functions as a tetramer or a pentamer.
17 lpha-helix form salt bridges in hexamers and pentamers.
18 assembled in vitro from bacterially produced pentamers.
19 otide, and multiple additions of GUCCA>p RNA pentamers.
20 is closed by incorporating 12 capsid-protein pentamers.
21 14S particles have long been presumed to be pentamers.
22 teraction sites along the interfaces between pentamers.
23 S particles are 488 kDa, confirming they are pentamers.
24 ly asymmetric structure made of hexamers and pentamers.
25 terminal domains of Npm2 and Np form similar pentamers.
26 served residues in the interface between two pentamers.
27 f replication by binding repeating G(A/G)GGC pentamers.
28 ectrostatic switch that favors hexamers over pentamers.
29 ctrostatic switch that favours hexamers over pentamers.
30 two GTPCH feedback regulatory protein (GFRP) pentamers.
31 -equivalent interactions within hexamers and pentamers.
32 te monomers, dimers, trimers, tetramers, and pentamers.
33 se that L1 protein is present in the form of pentamers.
34 orts of possible ion conductance through PLN pentamers.
35 capsid proteins are exclusively organised in pentamers.
36 intrinsic signals to segregate into distinct pentamers.
37 ilt of 36.1-36.6 degrees between consecutive pentamers.
38 oups, with lower accumulation of trimers and pentamers.
42 A binding sequence is split into overlapping pentamers (5 base pairs) for calculating transcription f
43 As the arms of the stargate grow from the pentamer, a rough disk the diameter of a capsid thickens
46 ow that the Z-alpha1AT trimer, tetramer, and pentamer all form ring-like structures in strong support
47 e minor capsid protein L2 associates with L1 pentamers, although it is not known if each L1 pentamer
48 by a 216S peak that was observed to contain pentamers among lipid debris in negatively stained grids
49 architectural element of the CA hexamer and pentamer and as a mechanistic element for generating lat
50 ce running along the 'top' surface of a DdrB pentamer and continuing down between two individual subu
52 ric organization of P1-P2 in the human stalk pentamer and functional non-equivalence of the individua
57 ates in intersubunit interactions in the CRP pentamer and is buried, to Gln resulted in a CRP mutant
59 l structure of Gemin2 bound to SmD1/D2/F/E/G pentamer and SMN's Gemin2-binding domain, a key assembly
62 cella spp. (BLS) is a highly stable dimer of pentamers and a scaffold with enormous plasticity on whi
63 hysiological partner locked Npm-N in ordered pentamers and counteracted the effects of phosphorylatio
69 d, AIM is stabilized by association with IgM pentamers and maintains its high circulating levels.
70 the relative quantities of monomers, dimers, pentamers and octamers in the C-S-H structure are measur
73 cently determined structure of the human IgM pentamer, and how this interaction could affect parasite
74 isulfide) with two subunits in a neighboring pentamer, and reinserts into the pentamer from which it
75 active site of SubA is not occluded by the B-pentamer, and the B-pentamer does not enhance or inhibit
76 t does not bind Ca(2+) at low pH and forms a pentamer, and the transition from tetramer to pentamer i
78 osahedrally symmetric: one is composed of 12 pentamers, and the other of 12 pentamers and 20 hexamers
80 at both Kmer-Sum and PWM stacking in the new pentamer approach along with a simplified integrative en
82 stantiate the fullerene conjecture, show how pentamers are accommodated at vertices, support the infe
84 a capsid varying according to how the twelve pentamers are distributed and its size depending on the
87 lexes gH/gL/gO and gH/gL/UL128/UL130/UL131A (Pentamer) are key targets of the human humoral response
89 These effects were mediated by alpha6alpha4* pentamers, as alpha6(L9'S) mice lacking alpha4 subunits
90 the periplasmic space of E. coli as soluble pentamers, as confirmed by multiangle light scattering a
91 he resulting receptors functionally resemble pentamers assembled with two copies of alpha4 and three
92 Structures of disulfide-linked hexamer and pentamer assemblies, as well as structures of the isolat
93 nicotine was present during, but not after, pentamer assembly and was caused by increased stability
94 We also show that a model of the hexamer/pentamer assembly can be readily generated with a single
96 sidues lining the 5-fold pore did not affect pentamer assembly or prevent association with the VP2 mi
97 ion in which higher-order assemblies of DdrB pentamers assist in the pairing of complementary ssDNA u
99 en compared to a series of related RNAs, the pentamer binds to rCUG repeats with 4.4- to >200-fold sp
101 ures of two relevant complexes: a THO hetero-pentamer bound to Sub2 at 6.0 A resolution; and Sub2 ass
102 amined the polymerization efficiencies of 20 pentamer building blocks each containing one of five dif
103 , the asymmetrical hexamer would appear as a pentamer by cryo-EM, a technology that acquires the aver
104 ng the human cytomegalovirus (HCMV) envelope pentamer complex (PC) are thought to be important for pr
105 zing antibodies (NAb) targeting the envelope pentamer complex (PC) composed of the subunits gH, gL, U
107 he gH/gL/gO or the gH/gL/UL128/UL130/UL131A (Pentamer) complex has been found to fulfill this role, a
108 ll types, while the gH/gL/UL128/130/131a (gH-pentamer) complex imparts specificity in infecting epith
109 veals that the mAbs bind to gH-trimer and gH-pentamer complexes and identify the antibodies' epitope
110 The gH/gL/gO and gH/gL/UL128/UL130/UL131 (Pentamer) complexes play a key role in HCMV cell entry a
115 ed to coat-coat protein interactions between pentamers, constitute the primary lattice-forming contac
116 experimental support for the hypothesis that pentamers containing a central helical bundle, observed
119 py and image reconstruction revealed altered pentamer coordination, possibly as a result of electrost
120 the tetramer crystallized at neutral pH, the pentamer crystallized at low pH, suggesting that prefere
121 the well-studied raft marker cholera toxin B pentamer (CTxB) that binds up to five GM1 glycosphingoli
122 ization with epithelial cell-tropic DB or gH pentamer-deficient DB preparations, (v) UV-inactivated r
124 nges of a short repeat, [VPGVG]5, an alanine pentamer, desmosine, and isodesmosine sites with and wit
125 the synthesis of the butadiyne-linked cyclic pentamer, despite the fact that the radii of their N5 do
128 is not occluded by the B-pentamer, and the B-pentamer does not enhance or inhibit the activity of Sub
129 e densities are crucial for the formation of pentamers, driven by cyclic hydrogen bonding between car
130 ave been able to directly visualize SV40 VP1 pentamers encapsidating short RNA molecules (500mers).
132 lations show that hIAPP forms from trimer to pentamer exhibit high structural stability with well-pre
133 in cells compared to a BTA monomer, with the pentamer exhibiting a 65-fold improvement in efficacy co
134 omer at its alpha-helical conformation and a pentamer fibril fragment of Abeta(42) peptide with or wi
135 transient low oligomeric states of receptor pentamers, followed by partial unfolding of helical part
140 These data are consistent with gH/gL/gO and Pentamer forming mutually exclusive cell entry complexes
142 ily of histone chaperones is identified by a pentamer-forming domain and multiple acidic tracts that
147 namics and conductance properties of the PLN pentamers from all-atom (AA) and coarse-grained (CG) mol
148 fied CyPs facilitated the dissociation of L1 pentamers from recombinant HPV11 L1/L2 complexes in a pH
150 ingle polycistronic vector encoding the five pentamer genes separated by "self-cleaving" 2A peptides
154 results reveal a regulatory role of the PLN pentamer in calcium homeostasis, going beyond the previo
157 re-fibrillar tetramer form and the fibrillar pentamer in the Abeta40 aggregation landscape disappears
158 or understanding the important role of the B-pentamer in the assembly and the intracellular trafficki
159 This is consistent with models of the PLB pentamer in which cytoplasmic domains fan out from the c
160 constructed in total nine different receptor pentamers in at least two different ways and expressed t
161 long with increased alpha2beta1gamma1 GABAAR pentamers in hippocampal slices using cell-surface cross
162 tein products, and assembly of protomers and pentamers in infected M1-D macrophages did not differ fr
165 n type 3A (5-HT3A) ICD assembles into stable pentamers in solution in the absence of the other two do
169 en followed to synthesize a second series of pentamers in which the Tz group is used as a pi-conjugat
170 ion, Gemin2 wraps around the crescent-shaped pentamer, interacting with all five Sm proteins, and gri
172 ivated catalytic site and confirmed that the pentamer interactions are essential for productive catal
173 t the calcium ion serves as a trigger at the pentamer interface, which switches on capsid disassembly
174 u15(SR)13 model features a cyclic [Au(I)-SR] pentamer interlocked with one staple trimer motif protec
175 ex vivo used human leukocyte antigen class I pentamers, intracellular cytokine staining, and fine map
176 ade of elongation reactions in which one VP1 pentamer is added at a time, with a rate of approximatel
177 ilt angle difference between the monomer and pentamer is approximately 13 degrees , showing that intr
178 amily; (iv) a molecular docking model of the pentamer is compatible with the location of the identifi
179 l surface antigen, would ensure that the IgM pentamer is oriented on the cell membrane with its C1q b
180 nfection of fibroblasts, and the gHgLpUL128L pentamer is required for infection of endothelial, epith
182 We find that when Mg(2+) is present, the pentamer is stabilized by the putative gating sites (M1/
184 tentials of mean force indicate that the PLN pentamer is unlikely to function as an ion channel.
186 A is also demonstrated, and the formation of pentamers is shown to be highly sensitive to local curva
187 e of beta and alpha subunits (two copies per pentamer) is consistent with a GABA(A)R homology model b
188 ns and restoration of gH/gL/UL128-UL131A (gH pentamer), (iv) equivalent neutralizing antibody titers
189 ggested an alternative structure for the PLN pentamer, known as the pinwheel model, which features a
190 ts core, the CCD of human strain ST3 forms a pentamer lacking the bound Ca(2+) despite the residues (
193 tamer interactions for a subset of the virus pentamers, likely because some of these residues form in
196 p)UL128, pUL130, and pUL131 (the gHgLpUL128L pentamer) neutralized HCMV infection with high potency.
197 subunits occupy specific positions in nAChR pentamers, observed FRET efficiencies from (alpha4)(3)(b
199 e, three-fourths-complete capsid lacking one pentamer of capsomers and a free, stable pentamer were o
200 ds missing one capsomer, capsids missing one pentamer of capsomers, and free pentamers of capsomers)
201 sults reveal a stoichiometry consisting of a pentamer of ExbB, a dimer of ExbD, and at least one TonB
203 ugh it is generally accepted that eIF2B is a pentamer of five non-identical subunits (alpha-epsilon),
204 astest and most powerful packaging motors, a pentamer of gp17 that translocates DNA at a rate of up t
210 ascent Shigella T3SA needle is topped with a pentamer of the needle tip protein invasion plasmid anti
212 amer that sandwiches DNA between two helical pentamers of ATP-associated AAA+ domains, sharply bendin
213 quentially added to the growing capsid, with pentamers of building blocks and incomplete capsids miss
214 onjecture, they are composed of hexamers and pentamers of capsid protein (CA), with the shape of a ca
215 missing one pentamer of capsomers, and free pentamers of capsomers) had been predicted in theoretica
216 round the icosahedral fivefold axes, forming pentamers of dimers that are thought to be assembly inte
217 atalytic large subunits (LSu) assembled into pentamers of dimers, (L2)5, and differs from Rubiscos fr
219 formed by approximately 250 hexamers and 12 pentamers of the CA protein is delivered to the cytoplas
225 iruses with capsids composed primarily of 72 pentamers of the viral VP1 protein, which forms the oute
226 tegration at genomic attP landing sites, two pentamers of UAS, the hsp70 core promoter, a multiple cl
228 ent decamer in solution, consistent with the pentamer-of-dimers assembly seen crystallographically.
229 l-atom models for the hexamer-of-hexamer and pentamer-of-hexamer elements as well as for the entire c
230 ed stable complexes of crenezumab with Abeta pentamer (oligomer model) and 16-mer (fibril model).
231 cages from a previously favored trimer to a pentamer or hexamer, and another from a trimer to a much
234 cerevisiae Fpr4, share the NPL fold and form pentamers, or a dimer of pentamers in the case of HD2.
235 c strength or temperature to form 5.8-MDa 12-pentamer particles, indistinguishable from native empty
236 sidues 69-71 and 193-197 of VP3 spanning the pentamer-pentamer interface, and another region incorpor
237 ow how the hydrophobic patch on top of the B-pentamer plays a dominant role in binding the A-subunit.
238 observed that polymerization of tetramer and pentamer PNA building blocks with a single lysine-based
239 structure observed in the four copies of the pentamer present in the asymmetric unit has been used to
240 iometry to low sensitivity (alpha4)3(beta2)2 pentamers primarily through this interaction in the endo
241 Papillomavirus capsids are composed of 72 pentamers reinforced through inter- and intrapentameric
242 nd are arranged in the capsid in consecutive pentamers related by a translation along the main viral
243 ssembly of the quasi-equivalent hexamers and pentamers requires remarkably subtle rearrangements in s
245 The X-ray crystal structure of an Ns1tbe pentamer revealed an all-cis PPI helix, and the CD curve
247 Interestingly, alpha2 was crystallized as a pentamer, revealing the intersubunit interactions in a w
250 through a novel RNA motif consisting of the pentamer sequence AGCCC with sequence restrictions at po
251 H(R)-CH2-NH-CO- residue in a model oligourea pentamer sequence was replaced by guest units bearing va
252 of CD3/CD8/PD-1/Tim-3, HSV-1, CD8(+) T cell pentamer (specific for a peptide derived from residues 4
253 e overall location of gH/gL-, gH/gL/gO-, and Pentamer-specific neutralizing antibody binding sites.
254 eptides and by HLA-A2-restricted core(18-27) pentamer staining and CD8(+) IFN-gamma enzyme-linked imm
255 CS) (CD107a, IFN-gamma, TNF-alpha and IL-2), pentamer staining and T-cell phenotyping were used to di
258 (V49A) had particularly large effects on PLB pentamer structure and PLB-SERCA regulatory complex conf
259 time frame, gamma peptides derived from the pentamer subunits are produced and are organized in a ve
261 to gB or gH/gL but also by antibodies to the pentamer, suggesting a potential role for the pentamer i
262 e, the first structural view of gH/gL/gO and Pentamer supporting the development of vaccines and anti
263 involves kinetically trapped dislocations of pentamer-templated proteins with hexameric organization.
264 utively secreting high levels of recombinant pentamer that displayed the functional antigenic sites t
267 esent ideas on the possible positions in the pentamer that may be occupied by the alpha5 subunit, and
270 llection of oligomers, including trimers and pentamers, that ultimately matures into amorphous aggreg
272 xperiments, we then demonstrate that, in the pentamer, three anaesthetic-sensitive rho1 subunits are
273 forming LS from Aquifex aeolicus (AaLS) into pentamers through a small number of rationally designed
274 c lattice containing a variable number of CA pentamers, thus allowing for closure of tubular or conic
276 Higher-order oligomeric models (ranging from pentamer to octamer), built by incremental addition of p
279 a homology-based structural model of the IgM pentamer using the recently obtained crystallographic st
284 TM protein structures ranging from dimers to pentamers, we show that our method predicts structures t
287 ncluding glycoprotein B (gB), gH/gL, and the pentamer, were evaluated for their effects on viral entr
288 asmic loop is vital for the integrity of the pentamer when Mg(2+) is absent from the M1/M2 sites.
289 red over its prefibrillar counterpart in the pentamer where an interconversion bottleneck appears.
290 50) values, the most potent inhibitor is the pentamer, which also inhibits the formation of rCAG repe
292 They are probably formed through trimers of pentamers, which are stabilised by the interaction of tw
293 forms highly unusual cyclic hydrogen-bonded pentamers, which combine with simultaneously formed FcCO
294 eals a diagonally bound receptor on each SAP pentamer with both D1 and D2 domains of the receptor con
296 etry showed that nicotine favors assembly of pentamers with (alpha3)2(beta4)3 stoichiometry; these ar
300 mer of E1/E2 may be further assembled into a pentamer, with 12 pentamers comprising a single HCV viri
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