ライフサイエンスコーパス: pentavalent

1 Conversely, oxidation of pentavalent 2-Cp* with AgSbF6 affords cationic [Cp*U(NPh

2 s increased since the discontinuation of the pentavalent (ABCDE) botulinum toxoid vaccine by the Cent

3 ements of VP5 subunits required to form both pentavalent and hexavalent capsomeres result in structur

4 al that mAb #9 binds to L1 molecules of both pentavalent and hexavalent capsomeres.

5 oups received SMS reminders before scheduled pentavalent and measles immunisation visits.

6 The product of this reaction is a pentavalent and monofunctionalized [O = U...OR]+ cation

7 ants, 87% and 86% received the third dose of pentavalent and oral poliovirus vaccine, respectively, b

8 The current standard to assess pentavalent antimonial (SSG) susceptibility of Leishmani

9 difficult to cure by chemotherapy (primarily pentavalent antimonials [Sb(V)]).

10 The pentavalent antimonials are considered the first-choice

11 ed by Leishmania braziliensis in Brazil with pentavalent antimony (Sb(v)) is associated with a high r

12 DL is a difficult to cure disease and pentavalent antimony (Sb(v)) is used as standard treatme

13 ial liver parasite killing, and synergy with pentavalent antimony (Sb) chemotherapy.

14 ring disease for which systemic therapy with pentavalent antimony (Sb) is effective but with side eff

15 ishmanicidal effect of conventional therapy, pentavalent antimony (Sb), also requires T cells and end

16 responsiveness to conventional chemotherapy (pentavalent antimony [Sb]) requires a T-cell-dependent m

17 The trivalent lanthanides and pentavalent antimony are found to be fully ordered in th

18 Pentavalent antimony compounds have been the mainstay of

19 t LmACR2 is responsible for reduction of the pentavalent antimony in Pentostam to the active trivalen

20 Pentavalent antimony is the conventional treatment; howe

21 lly significant predictors of the failure of pentavalent antimony treatment for cutaneous leishmanias

22 timony tartrate (PAT) and, more importantly, pentavalent antimony-carbohydrate complexes, such as sod

23 Here we report a group of pentavalent antimony-containing small molecule compounds

24 to cutaneous leishmaniasis (CL) treated with pentavalent antimony.

25 (3-nitro-4-hydroxybenzenearsonic acid) is a pentavalent aromatic arsenical that is used as antimicro

26 Pentavalent arsenic [As(V)] was found to be the predomin

27 NMR = 4900 g.mol(-1), D = 1.07) possessing a pentavalent arsenic acid (As(V)) alpha-chain end was tra

28 educed inorganic arsenate but not methylated pentavalent arsenicals.

29 Pentavalent aryl and heteroaryl bis(catechol) silicates

30 lutions contained a mixture of trivalent and pentavalent As species and that the pentavalent species

31 Methylated pentavalent As species are less toxic and are routinely

32 The results for the sums of trivalent and pentavalent As species corresponded well with the refere

33 at would consistently produce single-species pentavalent As standards, which eliminates As speciation

34 artile-range increases in trivalent, but not pentavalent, As species in EUC were positively and signi

35 Here we design an ALVAC/Pentavalent B/E/E/E/E vaccine to increase the diversity

36 sera from horses vaccinated with commercial pentavalent bacterin.

37 Pentavalent binding between cholera toxin and gangliosid

38 irus-induced gastroenteritis and, RotaTeq, a pentavalent bovine-based vaccine, and, Rotarix, a monova

39 The absence of mAb 5B6 from the pentavalent capsomeres and its inability to prevent vira

40 al differences for the 5B6 epitope in the 12 pentavalent capsomeres.

41 prepared via bioconjugation of unimolecular pentavalent construct 1-containing five prostate and bre

42 ffinity and IC50 measured for the respective pentavalent constructs.

43 or = 50 years old were immunized with either pentavalent Corynebacterium diphtheriae C7 (beta197) cro

44 served for large trivalent, tetravalent, and pentavalent counterions.

45 s the trend in coverage for tuberculosis and pentavalent did not significantly differ from zero.

46 and receipt of five infant vaccines: polio, pentavalent (diphtheria, tetanus, pertussis, hepatitis B

47 313 (95% CI-446 to -179; p<0.0001) fewer for pentavalent during the outbreak.

48 by computational docking of the high-energy, pentavalent form of the substrates to modeled structures

49 n a higher epitope ratio of the unimolecular pentavalent glycopeptide antigen to the carrier protein

50 ty of the manufacturing-scale formulation of pentavalent HBRV.

51 The pentavalent human-bovine reassortant rotavirus vaccine (

52 Live pentavalent human-bovine reassortant rotavirus vaccine i

53 Phase III studies of an oral, live, pentavalent, human-bovine reassortant rotavirus vaccine

54 Trivalent (Ia/II/III) and pentavalent (Ia/Ib/II/III/V) vaccines would cover 71/73

55 We measured concentrations of trivalent and pentavalent iAs methyl-As (MAs) and dimethyl-As (DMAs) s

56 here the synthesis and characterization of a pentavalent inhibitor for cholera toxin and Escherichia

57 CT B-subunit (CTB), which is the most potent pentavalent inhibitor for this target reported thus far.

58 g that inhibition of receptor binding by the pentavalent inhibitor is due to 1:1 inhibitor:toxin asso

59 a 1.46 A resolution crystal structure of the pentavalent inhibitor:toxin complex, which shows that th

60 d in order to generate arsanes from tri- and pentavalent inorganic arsenic species (iAs(III), iAs(V))

61 atalyze the interconversion of 5 and 6 via a pentavalent intermediate 8.

62 cts with the carbonyl group upon forming the pentavalent intermediate during phosphodiester hydrolysi

63 change from a stepwise mechanism involving a pentavalent intermediate for poorer leaving groups to a

64 lowed by subsequent formation of an unstable pentavalent intermediate that decomposes into cAMP and p

65 eactions, presumably by participating in the pentavalent intermediate transition state.

66 ew facile methodology for the preparation of pentavalent iodine compounds using peracetic acid as an

67 idizing reagents belonging to a new class of pentavalent iodine compounds with a pseudobenziodoxole s

68 ed earlier for the corresponding nonbranched pentavalent ligand.

69 Pentavalent ligands, in a "core-linker-finger" modular s

70 Consistent with this observation, the pentavalent lipid MVL5 exhibited lower toxicity and supe

71 s Mn(IV) species results in formation of the pentavalent Mn(V) nitride, [(TIMEN(xyl))Mn(N)](2+).

72 are retained by the five arms of the 5256 Da pentavalent MNPG-based inhibitor and that the initial se

73 The resulting pentavalent neoglycoprotein displays an inhibition poten

74 tions may include a 5a" state with nominally pentavalent nitrogen and a 6a" state.

75 ing biosynthesis and extrusion of an unusual pentavalent organoarsenical.

76 Substantial amounts of pentavalent organoarsenicals have been used as herbicide

77 nic compounds are far more toxic than either pentavalent organoarsenicals or inorganic arsenite.

78 and Rox(III) but not to inorganic As(III) or pentavalent organoarsenicals.

79 where it is broadly considered to reside as pentavalent P in phosphate minerals and organic esters.

80 Exceptions to pentavalent P include phosphine--PH3--a trace atmospheri

81 nvolving rapid and reversible formation of a pentavalent peroxide ate complex, prior to rate-limiting

82 osphoenolpyruvate and helps to stabilize the pentavalent phosphate transition state during phosphoryl

83 Six pentavalent pneumococcal conjugate vaccines (Pn-CRM197)

84 Pentavalent resistance occurred in 120 of 292 isolates (

85 vaccination, as compared with the risk after pentavalent rotavirus vaccination, was 9.4 (95% confiden

86 ain-specific vaccine effectiveness (VE) of a pentavalent rotavirus vaccine (RotaTeq) against rotaviru

87 Routine vaccination of U.S. infants with pentavalent rotavirus vaccine (RV5) began in 2006.

88 t uninfected (HEU) African infants receiving pentavalent rotavirus vaccine (RV5) in a clinical trial.

89 Pentavalent rotavirus vaccine (RV5) was introduced into

90 Pentavalent rotavirus vaccine (RV5), a live, oral attenu

91 RotaTeqTM is a pentavalent rotavirus vaccine based on a bovine rotaviru

92 A quadrivalent precursor to the pentavalent rotavirus vaccine candidate RotaTeq was eval

93 irst low-income African country to introduce pentavalent rotavirus vaccine into its routine national

94 For the pentavalent rotavirus vaccine, 1,301,810 doses were admi

95 Four strains were related to pentavalent rotavirus vaccine, whereas one was related t

96 oncurrent cohort of infants who received the pentavalent rotavirus vaccine.

97 esicles did not transport As(III), MAs(V) or pentavalent roxarsone.

98 rns exist about whether monovalent (RV1) and pentavalent (RV5) rotavirus vaccines provide adequate pr

99 both the monovalent (RV1; 2-dose series) and pentavalent (RV5; 3-dose series) vaccines were introduce

100 li, that confers resistance to trivalent and pentavalent salts of the metalloid arsenic.

101 id R773 produces resistance to trivalent and pentavalent salts of the metalloids arsenic and antimony

102 operons produce resistance to trivalent and pentavalent salts of the metalloids arsenic and antimony

103 Pk trisaccharide, the in vivo ligand for the pentavalent Shiga-like toxin binding subunit (SLT-1B), w

104 -syn and the 2,3-anti aldehydes form stable, pentavalent silicate intermediates (98 and 100) with PhS

105 lent and pentavalent As species and that the pentavalent species was approximately 8% more sensitive

106 ated and aromatic arsenicals by oxidation to pentavalent species.

107 In marked contrast, pentavalent SSG, the drug of choice for the treatment of

108 e related metalloid antimony, present in the pentavalent state as a complex in drugs such as sodium s

109 uman antibodies from subjects immunized with pentavalent toxoid preparations were detectable at dilut

110 Rather, the pair likely stabilizes the pentavalent transition state necessary for phospho-trans

111 re shows that Mn1 is poised to stabilize the pentavalent transition state of guanylylation while a se

112 e only role for His(632) is to stabilize the pentavalent transition state through hydrogen bonding to

113 horyl oxygen, Arg61 and Asn119 stabilize the pentavalent transition state, and Asn119 also binds to t

114 coordinate the substrates and stabilize the pentavalent transition state.

115 tacking orientation, leading to the presumed pentavalent transition state.

116 itrophenolate), Mg(2+) likely stabilizes the pentavalent transition state.

117 and characterization of the singly reduced, pentavalent uranyl cation [UO2]+ has been reported.

118 he efficacy of a live, oral bovine rotavirus pentavalent vaccine (BRV-PV, Serum Institute of India) t

119 All children were to receive OPV with pentavalent vaccine (diphtheria, tetanus, pertussis, Hae

120 visit, with infants receiving IPV alongside pentavalent vaccine (which covers diphtheria, tetanus, a

121 oxoid remains an effect vaccine, the current pentavalent vaccine against botulism is in limited suppl

122 In developing a pentavalent vaccine for the prevention of GBS infections

123 If the pentavalent vaccine had been delivered during the CHDs i

124 hat immunization of rhesus macaques with the pentavalent vaccine results in protection of 55% of pent

125 eneration rotavirus vaccines RotaTeq (RV5, a pentavalent vaccine) and Rotarix (RV1, a monovalent vacc

126 three doses of polio vaccine, three doses of pentavalent vaccine, and measles vaccine) by 12 months o

127 ased infection risk that are improved by the pentavalent vaccine.

128 eks who had not yet received a first dose of pentavalent vaccine.

129 lent vaccine results in protection of 55% of pentavalent-vaccine-immunized macaques from simian-human

130 lio 0 (birth-4 weeks), three polio and three pentavalent vaccines (4 weeks-2 months; 8 weeks-4 months