ライフサイエンスコーパス: pentobarbital

1 t and antagonist binding but not affected by pentobarbital.

2 thane, but not in animals anaesthetized with pentobarbital.

3 oxicity and altered the anesthetic effect of pentobarbital.

4 ns exposed to the GABA allosteric modulator, pentobarbital.

5 its were examined in the presence of GABA or pentobarbital.

6 gs from HEK cells in the presence of GABA or pentobarbital.

7 onstants (4.5-6.0 ms) that were modulated by pentobarbital.

8 es were 50 mg/kg chloral hydrate and 4 mg/kg pentobarbital.

9 Such changes require the presence of pentobarbital.

10 stable RNA, whose stability is unaffected by pentobarbital.

11 probed on channel activation by propofol and pentobarbital.

12 conventional hypnotics, diazepam and sodium pentobarbital.

13 activated by either GABA alone or GABA plus pentobarbital.

14 g by GABA, with little change in efficacy of pentobarbital.

15 ive effects of ethanol and ketamine, but not pentobarbital.

16 8+/-0.03 ml/min in 45 cats anesthetized with pentobarbital.

17 gnificantly altered the MI induced by sodium pentobarbital.

18 sia was maintained, using 2 to 3 mg/kg/hr iv pentobarbital.

19 + but retained their sensitivity to GABA and pentobarbital.

20 havioral responses to general anesthetics or pentobarbital.

21 uculline only partially blocked responses to pentobarbital.

22 esthetized with intraperitoneal injection of pentobarbital.

23 its, although cells gave strong responses to pentobarbital.

24 rats were killed using an overdose of sodium pentobarbital.

25 d animals with a GABA(A) allosteric agonist, pentobarbital.

26 spinal cord of rats anesthetized with sodium pentobarbital.

27 bstantial amounts during channel blockade by pentobarbital.

28 ficial dorsal horn of mice anesthetized with pentobarbital.

29 idence of adverse respiratory events than is pentobarbital.

30 with intravenously administered propofol or pentobarbital.

31 f GABA-site agonists, antagonists, BZDs, and pentobarbital.

32 e fewer episodes of oxygen desaturation with pentobarbital (0.2%) than with chloral hydrate (1.6%) (P

33 se event rate during sedation was lower with pentobarbital (0.5%) than with chloral hydrate (2.7%) (P

34 tion in the maximal direct channel-gating by pentobarbital (1 mm) and etomidate (100 mum) and for inc

35 Diazepam (10 microM) and pentobarbital (1 mM) potentiate muscimol-stimulation.

36 GABA currents (10-20%); positive modulators, pentobarbital (10 microM), midazolam (1 microM) and lore

37 as significantly longer with PO than with IV pentobarbital (18 minutes +/- 11 vs 7 minutes +/- 7; P <

38 ital (4-8 mg per kilogram body weight) or IV pentobarbital (2-6 mg/kg), depending on the presence of

39 e obstruction than did patients sedated with pentobarbital (23% vs 0%, P < .001).

40 Anesthesia was induced with pentobarbital (25 mg/kg iv) and maintained (10 mg/hr) af

41 Sedation was achieved with pentobarbital (3-5 mg/kg) or chloral hydrate (75 mg/kg).

42 Patients received pentobarbital (3.0-7.0 mg per kilogram of body weight) o

43 Modulators such as pentobarbital, 3 alpha-hydroxy-5 alpha-pregnan-20-one, m

44 The animals were anesthetized with pentobarbital (30 mg/kg) by intraperitoneal injection.

45 etamine, 20 mg/kg intramuscularly and sodium pentobarbital, 30 mg/kg intravenously), intubated, and m

46 Dogs were anesthetized (sodium pentobarbital, 30 mg/kg intravenously), intubated, and m

47 younger than 12 months were sedated with PO pentobarbital (4-8 mg per kilogram body weight) or IV pe

48 After maternal anesthesia (pentobarbital, 60 mg/kg IP), laparotomy, and sequential

49 e residues of the beta3 subunit which affect pentobarbital action on the gamma-aminobutyric acid type

50 1)K219C and alpha(1)K221C affected GABA- and pentobarbital-activated currents differently, suggesting

51 Pentobarbital activation of the receptor increased the r

52 Pentobarbital activation of the receptor significantly s

53 Here, we examined whether pentobarbital activation triggers movements in the GABA(

54 Proteolytic cleavage impairs GABA but not pentobarbital activation, strongly suggesting that confo

55 (s.c.) injection of KA followed after 1 h by pentobarbital administration.

56 First, we studied how pentobarbital affects BV2 mouse microglial cells in cult

57 ation by pentobarbital is due to a change in pentobarbital affinity for the receptor.

58 ic acid hydrobromide (SR-95531; antagonist), pentobarbital (allosteric modulator), and flurazepam (al

59 Pentobarbital alone (100 microM) activated channels with

60 that affect the severity of withdrawal from pentobarbital also influence ethanol and zolpidem withdr

61 rbital were not specific to c-Fos, such that pentobarbital also suppressed expression of ITFs FosB an

62 Moreover, pentobarbital altered the rates of cysteine modification

63 nd changes in kinetic properties produced by pentobarbital among chimeric and wild type receptors, we

64 y of alphaxalone (an anesthetic steroid) and pentobarbital (an anesthetic barbiturate) to directly ac

65 A), second- (2A) and third-order (3A) MAs of pentobarbital-anaesthetized Young (3-6 months) and Old (

66 rofound changes in the in vivo metabolism of pentobarbital and acetaminophen indicated that extrahepa

67 leep have also been observed with triazolam, pentobarbital and ethanol microinjection.

68 eric ligands such as the general anesthetics pentobarbital and etomidate can activate the receptor.

69 in the presence of the allosteric activators pentobarbital and etomidate resulted in an enhanced curr

70 ocked by bicuculline and were potentiated by pentobarbital and flunitrazepam.

71 Sodium pentobarbital and ketamine, two agents commonly used in

72 The application of pentobarbital and loreclezole, which increase GABAR curr

73 Sleep time response to injection of pentobarbital and loss of righting reflex and response t

74 rd minipigs (20 to 25 kg), anesthetized with pentobarbital and mechanically ventilated on an FIO2 of

75 esponse was more sensitive to enhancement by pentobarbital and more readily antagonized by both bicuc

76 vity of phase 1 and phase 2 to inhibition by pentobarbital and NBQX mirrors the differential sensitiv

77 Although oral pentobarbital and oral chloral hydrate are equally effec

78 genetic correlations between withdrawal from pentobarbital and other sedative agents.

79 d the nonselective GABA(A) receptor agonists pentobarbital and pregnanolone.

80 pared with a 2-3-fold response in wild type, pentobarbital and propofol enhanced less than 0.5-fold;

81 r direct activation of the GABAA receptor by pentobarbital and propofol is absent on alpha 4-containi

82 The GABAergic anesthetics pentobarbital and propofol were also effective.

83 ors, metabolic suppressive agents (high-dose pentobarbital and propofol), etomidate, and AI status.

84 IACUC approval, mice were anesthetized with pentobarbital and subjected to 30 minutes of superior me

85 greater sensitivity of the GABAd response to pentobarbital and the GABAA antagonists, this could not

86 t for activation of the receptor by GABA and pentobarbital and the regulation of GABARs by numerous a

87 o the effective inhibitory concentrations of pentobarbital and to the rate of onset of inhibition tha

88 Two anesthetics namely pentobarbital and urethane, hypothesized to have distinc

89 We also observed decreased pentobarbital, and 5 alpha 3 alpha potentiation of GABA

90 insertions on allosteric modulator actions, pentobarbital, and benzodiazepines, have different subun

91 re kept fasting overnight, anesthetized with pentobarbital, and given intraperitoneally either the be

92 ties of nAChRs to acetylcholine, isoflurane, pentobarbital, and hexanol.

93 rations of the general anesthetics propofol, pentobarbital, and isoflurane.

94 s--which included fentanyl, chloral hydrate, pentobarbital, and midazolam hydrochloride--by using the

95 that GABA response, and its potentiation by pentobarbital, and neurosteroid, 5 alpha 3 alpha, are at

96 ate (BNP), 1,1'-bi-2-naphthol, secobarbital, pentobarbital, and temazepam.

97 ks later, rats were killed by an overdose of pentobarbital, and the carotid arteries were evaluated f

98 weeks later, rats were killed by overdose of pentobarbital, and the carotid arteries were subjected t

99 s later, the rats were killed by overdose of pentobarbital, and the injured right and uninjured contr

100 Glycerol induced severe ARF under pentobarbital anesthesia (Cr, 2.8 +/- 0.3 mg/dl; severe

101 Pentobarbital anesthesia abolished the unconditioned mot

102 All experiments were performed under pentobarbital anesthesia and controlled conditions of no

103 After intraperitonial pentobarbital anesthesia and tracheostomy, a craniotomy

104 in the brain of rats habituated to repeated pentobarbital anesthesia or saline administration.

105 present the optimal levels attainable during pentobarbital anesthesia with normal lungs.

106 With animals under pentobarbital anesthesia, AHF and flow to blood (equated

107 After anterior chamber cannulation under pentobarbital anesthesia, aqueous humor formation (AHF),

108 brain was severalfold higher than under deep pentobarbital anesthesia, measured previously in our lab

109 ng these drugs in the presence or absence of pentobarbital anesthesia.

110 stimulation of the heteronymous nerve under pentobarbital anesthesia.

111 We determined whether pentobarbital anesthetic is required to culture postmort

112 single T3-T4 spinal neurons were recorded in pentobarbital anesthetized male rats.

113 of single T(3)-T(4) neurons were recorded in pentobarbital anesthetized male rats.

114 Seventy pentobarbital anesthetized Sprague-Dawley rats.

115 the nucleus gigantocellularis pars alpha of pentobarbital anesthetized Sprague-Dawley rats.

116 of single T(3)-T(4) neurons were recorded in pentobarbital anesthetized, paralyzed and ventilated mal

117 at lumbar spinal cord segments 2-3 in sodium pentobarbital anesthetized, paralyzed and ventilated rat

118 r 2-3 spinal cord segments (L2-L3) in sodium pentobarbital anesthetized, paralyzed and ventilated rat

119 r 2-3 spinal cord segments (L2-L3) in sodium pentobarbital anesthetized, paralyzed, and artificially

120 horacic (T3) spinal neurons were recorded in pentobarbital anesthetized, paralyzed, and ventilated ma

121 ingle T9-T10 spinal neurons were recorded in pentobarbital anesthetized, paralyzed, and ventilated ma

122 ingle T9-T10 spinal neurons were recorded in pentobarbital anesthetized, paralyzed, ventilated male r

123 r thoracic (T3) spinal cord were recorded in pentobarbital anesthetized, ventilated and paralyzed mal

124 gle L6 to S2 spinal neurons were recorded in pentobarbital-anesthetized and paralyzed rats with dextr

125 Sodium pentobarbital-anesthetized animals were randomly assigne

126 In three pentobarbital-anesthetized cynomolgus monkeys, IOP was s

127 In pentobarbital-anesthetized dogs, rectangular monophasic

128 In seven pentobarbital-anesthetized intact dogs arterial and left

129 ociceptive flexion reflex were obtained from pentobarbital-anesthetized Intact rats and from both, an

130 and noxious chemical cardiac stimulation in pentobarbital-anesthetized male and proestrous female ra

131 Pentobarbital-anesthetized pigs were intubated and mecha

132 was over four times as large as that in the pentobarbital-anesthetized preparations.

133 In the pentobarbital-anesthetized rabbit, alpha- and beta- adre

134 r of these drugs was able to induce c-Fos in pentobarbital-anesthetized rats (50 mg/kg, i.v.).

135 ) or intra-arterial (i.a.) administration to pentobarbital-anesthetized rats pretreated with beta-end

136 try, blood flow from the anterior choroid in pentobarbital-anesthetized rats was measured continuousl

137 In pentobarbital-anesthetized rats, mid-cycle cathodal acti

138 trauma was applied on the left hind limb of pentobarbital-anesthetized rats.

139 sed after 1-16 weeks of galactose feeding in pentobarbital-anesthetized rats.

140 Thus, in nine pentobarbital-anesthetized, mechanically ventilated dogs

141 ncy [thiopental ( approximately 280 microM), pentobarbital ( approximately 310 microM), phenobarbital

142 The R(+)-enantiomers of isobarbital and pentobarbital are approximately 2-fold more potent in in

143 ts significantly less severe withdrawal from pentobarbital as well as other sedative-hypnotics (zolpi

144 esults in cells that have large responses to pentobarbital (as expected) but also show appreciable re

145 rease in LH release, rats were injected with pentobarbital at 13.55 h to block the afternoon LH surge

146 jections of the GABA(A) receptor potentiator pentobarbital at 20 mg/kg for 4 weeks rescued the learni

147 than did HPW mice, but did not consume more pentobarbital at a higher or lower concentration.

148 Coapplication of pentobarbital, benzodiazepines, and zolpidem all signifi

149 at residues of the beta3 subunit involved in pentobarbital binding to GABAA receptors are located dow

150 Pentobarbital binding/gating resulted in no observable m

151 The barbiturate pentobarbital binds to gamma-aminobutyric acid type A (G

152 hed response to the anxiolytics diazepam and pentobarbital, both of which interact with GABA-A recept

153 response to apnea in rats anesthetized with pentobarbital but increased with urethane.

154 Both of their mRNAs are inducible by pentobarbital but otherwise behave very differently.

155 alpha1E122C was decreased by either GABA or pentobarbital but was unaltered by SR-95531 binding, whe

156 On the other hand, pentobarbital by itself strongly induced c-Fos expressio

157 Depending on its concentration, pentobarbital can potentiate (approximately 10-100 micro

158 ge to a more swollen, 'activated' shape with pentobarbital (cell area increased by approximately 20%,

159 , midazolam, diazepam, clonazepam, propofol, pentobarbital, chloral hydrate, halothane, isoflurane, s

160 A receptor (GABA(A))-enhancing class (e.g., pentobarbital, chloral hydrate, muscimol, and ethanol) p

161 (CYP) and heme oxygenase (HO) activities, in pentobarbital clearance, and in total plasma cholesterol

162 ncreased from 12 +/- 4 to 62 +/- 9 pS as the pentobarbital concentration was raised from 10 to 500 mi

163 We examined the effect of a range of pentobarbital concentrations on 0.5 microM gamma-aminobu

164 ncrease during application of low modulating pentobarbital concentrations, and it showed a much great

165 At higher pentobarbital concentrations, the cluster open probabili

166 1 structural elements important for GABA and pentobarbital current activation are distinct.

167 For alpha(1)K221Cbeta(2) receptors, pentobarbital decreased the rate of cysteine modificatio

168 d: ethanol, methanol, n-propanol, t-butanol, pentobarbital, diazepam, and allopregnanolone.

169 e concatemeric receptors were potentiated by pentobarbital, diazepam, and the neurosteroid (3alpha,5a

170 1 and a low, non-activating concentration of pentobarbital did not alter their modification rates, su

171 infusion, four patients required intravenous pentobarbital due to poor ICP control.

172 itutions had little to no effect on GABA and pentobarbital EC(50) values.

173 The pentobarbital EC(50)(0.5 microM GABA) value was 22 +/- 4

174 pentobarbital prevented the shNKCC1 and the pentobarbital effects on NPC proliferation, suggesting t

175 nge of sedative agents, including triazolam, pentobarbital, ethanol and adenosine, into the medial pr

176 ned by the coexpression of alpha1 and beta3, pentobarbital exhibited lower potentiation of GABA-evoke

177 e Sprague-Dawley rats were anesthetized with pentobarbital, fitted with femoral arterial catheters an

178 blockers do not compete with alphaxalone or pentobarbital for a single class of sites on the GABAA r

179 ts received 2419 (1264 PO, 1155 IV) doses of pentobarbital for sedation.

180 ced the currents elicited by alphaxalone and pentobarbital from wild-type GABAA receptors; however, g

181 on GABA(A) receptors (muscimol, propofol and pentobarbital; 'GABAergic agents') and to ketamine, a ge

182 s occurred in the propofol group than in the pentobarbital group (12% vs 0%, P = .03).

183 er recovery profile than did patients in the pentobarbital group (34 minutes +/- 17 vs 100 minutes +/

184 For alpha(1)beta(2)K215C receptors, pentobarbital had no effect whereas GABA increased the m

185 site antagonist) decreased the rate, whereas pentobarbital had no effect.

186 eas DMCM, GABA, and the allosteric modulator pentobarbital had no effects, demonstrating that gamma(2

187 Also, pentobarbital had opposite effects on the desensitizatio

188 PO pentobarbital has comparable effectiveness and a lower r

189 Pentobarbital, however, triggers different movements in

190 The dogs were anesthetized (30 mg/kg pentobarbital, i.v.), intubated, and cannulated in one f

191 In preparations deeply anesthetized with pentobarbital, Ia current either decreased with depolari

192 LPW mice consumed more pentobarbital in a solution of a moderate concentration

193 residues in the actions of propofol but not pentobarbital in beta3 receptors.

194 f respiratory complications compared with IV pentobarbital in infants younger than 12 months; its use

195 Anesthesia was induced with 65 and 45 mg/kg pentobarbital in male and female rats, respectively.

196 om 6.5 +/- 0.3 to a nadir of 2.9 +/- 0.3 for pentobarbital; in nicotine-exposed animals, frequency fe

197 as for alpha1beta3gamma2L receptor channels, pentobarbital increased mean open duration by increasing

198 Pentobarbital increased steady-state alpha1beta3delta re

199 We demonstrated that the presence of pentobarbital increased the dendrimer nanoparticle uptak

200 WT mice after administration of ketamine or pentobarbital, indicating that the mechanism of enhanced

201 These results indicate that GABA and pentobarbital induce different structural rearrangements

202 Pentobarbital induced a decrease in glucose utilisation

203 High concentrations of pentobarbital induced a decrease in TMRM fluorescence (F

204 Further, pentobarbital-induced channel activation accelerated mod

205 ned voltage clamp and fluorometry to monitor pentobarbital-induced channel activity and local protein

206 under conditions of halothane anesthesia and pentobarbital-induced isoelectricity.

207 ries of homologous compounds in antagonizing pentobarbital-induced narcosis when administered intrave

208 Abcb6 null mice are more susceptible to pentobarbital-induced sleep and zoxazolamine-induced par

209 xposure to pregnanolone, GABA, flurazepam or pentobarbital induces complete uncoupling of barbiturate

210 Whether pentobarbital induces new conformations or promotes conf

211 usion criteria were age <18 yrs old, ongoing pentobarbital infusion, or markedly increased intracrani

212 We have demonstrated that sodium pentobarbital inhibited the activation of the human red

213 Ethanol and pentobarbital inhibited the function of both wild-type a

214 ncluded hypothermia, hypocarbia, intravenous pentobarbital, intravenous mannitol and vasopressor titr

215 The dogs were anesthetized (30 mg/kg iv pentobarbital), intubated, and cannulated in one femoral

216 Animals were anesthetized with pentobarbital, intubated, and ventilated, and monitoring

217 Animals were anesthetized with pentobarbital, intubated, paralyzed, and mechanically ve

218 he concentration dependence of activation by pentobarbital is due to a change in pentobarbital affini

219 may be contributing factors, especially when pentobarbital is used.

220 nesthesia was maintained using 8-15 mg/kg/hr pentobarbital (iv) and controlled by continuous hemodyna

221 tween wakefulness and anesthesia showed that pentobarbital, ketamine, chloral hydrate, urethane, or m

222 Intestinal IRI with pentobarbital led to significant small intestinal dysfun

223 dent GABAR currents that were potentiated by pentobarbital, loreclezole, and lanthanum and inhibited

224 Therefore, pentobarbital may regulate this L/S ratio by affecting t

225 Pigs were anesthetized with ketamine and pentobarbital, mechanically ventilated, hemodynamically

226 ication rates, suggesting that the GABA- and pentobarbital-mediated changes in rates reflect gating m

227 pre-M1 region is involved in both GABA- and pentobarbital-mediated gating transitions.

228 Potentiation of GABA responses by pentobarbital, midazolam, and loreclezole all increased

229 e reported who had therapy with: thiopental, pentobarbital, midazolam, propofol, ketamine, inhalation

230 techniques, we demonstrate isoform-specific pentobarbital modulation of low-efficacy, minimally dese

231 The effects of propofol, octanol, and pentobarbital on alpha1H currents were indistinguishable

232 ave been extensively studied, the effects of pentobarbital on kinetic properties of alphabetadelta GA

233 ated the effect of a commonly used sedative, pentobarbital, on glial cells and their uptake of nanopa

234 volatile anesthetics, but not of ethanol or pentobarbital, on the GluR6 receptor.

235 At high concentrations, the barbiturate pentobarbital opens GABA(A)R channels with similar condu

236 ne produced only a partial block of response pentobarbital or alphaxalone, and bicuculline only parti

237 ficantly faster than that in the presence of pentobarbital or gabazine or in resting receptors.

238 llowed by 4 hours of equianesthetic doses of pentobarbital or isoflurane.

239 rough lateral striatum of anesthetized rats (pentobarbital or ketamine) revealed spontaneously discha

240 lowing the systemic administration of either pentobarbital or ketamine.

241 Outcomes of all infants who received oral pentobarbital or oral chloral hydrate for sedation betwe

242 ents, particularly those receiving high-dose pentobarbital or propofol.

243 GABAergic modulators propofol, etomidate, or pentobarbital or the steroid alphaxalone.

244 uring wakefulness but not during anesthesia (pentobarbital or urethane).

245 r GABA and the allosteric agonists propofol, pentobarbital, or alfaxalone can be understood as reflec

246 allosterically acting anesthetics propofol, pentobarbital, or alfaxalone.

247 teady-state currents by propofol, etomidate, pentobarbital, or alphaxalone were at similar or lower d

248 -exposed preparations with both muscimol and pentobarbital (P < 0.001 for both).

249 mol and from 6.4 +/- 0.2 to 1.7 +/- 0.4 with pentobarbital (P < 0.05 in all cases).

250 Rats were anaesthetized with pentobarbital, paralysed and ventilated.

251 ) for GABA and for the allosteric activators pentobarbital (PB) and propofol indicating that these re

252 E4-KI mice with a GABAA receptor potentiator pentobarbital (PB) before and during behavioral tests re

253 -KI mice with the GABAA receptor potentiator pentobarbital (PB) for 4 weeks before and during MWM res

254 ne-4-sulfonic acid (P4S), and the effects of pentobarbital (PB) on single-channel activity were exami

255 signals identified by GC/MS as diagnostic of pentobarbital (PB) were not artifacts of derivatization

256 influx were both inhibited (> 80%) by 10 mM pentobarbital (PB).

257 ous oxide, ketamine, barbiturates, propofol, pentobarbital, phenobarbital.

258 At 100 microM pentobarbital plus 0.5 microM GABA, the conductance seem

259 In 1 mM pentobarbital plus 0.5 microM GABA, the single-channel c

260 Pentobarbital potentiated alpha 4 beta 1 gamma 2 recepto

261 ns of the delta subunit that are involved in pentobarbital potentiation and increased desensitization

262 ofen blocks ethanol but not flunitrazepam or pentobarbital potentiation of GABA(A) IPSCs.

263 Combining shNKCC1 and pentobarbital prevented the shNKCC1 and the pentobarbita

264 gamma-aminobutyric acid-mimetic drugs [i.e., pentobarbital (PTB)] associated with a down-regulation o

265 We find that anesthetic levels of pentobarbital reduce taste nerve responses apparently by

266 e intrinsically very labile, but exposure to pentobarbital renders them stabilized beyond what can be

267 potentiation of alpha1beta3delta currents by pentobarbital required the delta subunit sequence from t

268 nist picrotoxin abolished this rescue, while pentobarbital rescued learning deficits in the presence

269 rousal assays, TAL shortened sleep time with pentobarbital sedation in WT and R2ko mice by 44 and 49%

270 pofol sedation as a potential alternative to pentobarbital sedation.

271 r the functional properties of activation by pentobarbital, sensitivity to diazepam, potentiation by

272 lurane) or with a nonfluorinated anesthetic (pentobarbital) served as controls.

273 GABA, SR-95531, and pentobarbital slowed N-biotinylaminoethyl methanethiosul

274 ) receptor agonists muscimol (250 microM) or pentobarbital sodium (60 microM) to the brainstem led to

275 His seizures required continuous pentobarbital sodium infusion to be controlled.

276 ioles in cremaster muscles of anaesthetized (pentobarbital sodium, 65 mg kg(-1)) mice.

277 d measured consumption of and preference for pentobarbital solutions in HPW and LPW mice.

278 urating GABA concentrations, the barbiturate pentobarbital substantially increased the amplitude and

279 lly, with saturating concentrations of GABA, pentobarbital substantially potentiated peak alpha1beta3

280 e open more in the presence of both GABA and pentobarbital than in the presence of either drug alone.

281 ition by NBQX but more sensitive to block by pentobarbital than phase 1.

282 in transduction of the allosteric effect of pentobarbital to enhance alpha1beta3delta currents and t

283 Second, we investigated how pentobarbital treatment affected nanoparticle uptake.

284 Following pentobarbital treatment of wild-type flies, the levels o

285 Pentobarbital treatment resulted in two-fold increases i

286 Pentobarbital was a strong activator of both alpha4beta2

287 ective, the incidence of adverse events with pentobarbital was significantly reduced.

288 Use of high-dose propofol and pentobarbital was strongly associated with lower cortiso

289 lity, recorded in the presence of 100 microm pentobarbital, was 0.7.

290 , 2.5 years +/- 1.7) who previously received pentobarbital were included.

291 The suppressive effects of pentobarbital were not specific to c-Fos, such that pent

292 ion of GABA or by co-application of GABA and pentobarbital were recorded using the patch clamp techni

293 roglial cells in the presence and absence of pentobarbital were treated with fluorescently-labeled, h

294 other agents like midazolam, lorazepam, and pentobarbital were used in the other ten (24%) patients

295 Thirty dogs anesthetized with Na-pentobarbital were ventilated by a positive pressure res

296 eement with direct, nonpolar interactions of pentobarbital with a water-exposed nonpolar patch on the

297 selectively bred to display severe and mild pentobarbital withdrawal HICs, respectively.

298 We also confirm a pentobarbital withdrawal locus within this interval, sug

299 High and Low Pentobarbital Withdrawal mice (HPW and LPW) were selecti

300 rge effect on predisposition to barbiturate (pentobarbital) withdrawal to a 0.44 Mb interval of mouse