ライフサイエンスコーパス: peptide T

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1 ith maximal effects on PKA noted at 10(-12)M peptide T.

2 before and one after 12 wk of treatment with peptide T.

3 Using five SPPs (SPACE peptide, TD-1, polyarginine, a dermis-localizing peptide

4 essed the potential of the fusion inhibitory peptide T-1249 for development as a vaginal microbicide

5 The fusion inhibitory peptide T-20 contains an additional tryptophan-rich sequ

6 The synthetic peptide T-20, which corresponds to a sequence within the

7 de receptor by f-met-leu-phe and HIV-derived peptide T-20-suppressed IL-12 p70 production from human

8 mino acid substitutions within the synthetic peptide T(249)-F(260), identified a major role for R(250

9 ormation, is different from that of a longer peptide, T(40), corresponding to the entire 40-amino aci

10 or no Ab response could be detected against peptides t alpha 182-198 or t alpha 146-162 itself.

11 The D-Ala1-peptide T-amide (DAPTA) peptide was selected as a target

12 intestinal peptide (VIP) and DAPTA (D-ala(1)-peptide T-amide, a gp120-derived octapeptide homologous

13 Because treatment of patients with peptide T (an octapeptide sequence found in the human im

14 These results indicate that peptide T and gp120 protein may inversely alter the intr

15 tion, studies were initiated to determine if peptide T and gp120 protein treatment of normal and psor

16 The presence of peptide T blocked this effect of the gp120 protein.

17 crystal x-ray diffraction for the synthetic peptide t-butoxycarbonyl--beta-Phe-beta-Phe-D-Pro-Gly-be

18 lem, we tested whether covalently coupling a peptide T cell determinant, OVA(323-339), to transferrin

19 tumor-associated Ags and their corresponding peptide T cell epitopes.

20 strate a previously unrecognized mode of MHC-peptide-T cell receptor interaction.

21 used to define structural aspects of the MHC/peptide/T cell receptor interaction and to study the sig

22 l and functional characterization of the MHC/peptide/T cell receptor recognition unit.

23 ity for DQ0602 molecules than the VP16 33-52 peptide, T cells that recognized the VP16 369-380 peptid

24 e from the interactions among populations of peptides, T cells and MHC molecules?

25 In naturally processed peptides, T cells only recognize posttranslationally alt

26 Furthermore, the putative gp120 antagonist, Peptide T (DAPTA), prevented the suppression of GH by gp

27 Treatment of normal human fibroblasts with peptide T did not result in any change in PKA levels.

28 Peptide T exhibited a biphasic dose dependent response,

29 The phage-selected peptide t(F)2 has three of the four amino acids crucial

30 Peptide t(F)2's higher affinity for the ASL(Phe)-Cm(32),

31 One of the peptides selected, peptide t(F)2, exhibited the highest specificity and mos

32 osed of the immunoadjuvant Pam(3)CysSK(4), a peptide T(helper) epitope and an aberrantly glycosylated

33 Peptide T is an octapeptide under investigation for trea

34 Together with peptides, T lymphocytes respond to hydrophobic molecules

35 was considerably less stable than the parent peptide (T(m) = 30 degrees C).

36 ightly more thermally stable than the parent peptide (T(m) = 37 vs 34 degrees C), while the peptide c

37 n the melting temperatures of the other four peptides (T(m) approximately 346-350 K).

38 for the Arg-, Val-, Glu-, and Asp-containing peptides, T(m) < 0 degrees C.

39 tment protocol with 1.2 mg/day of intranasal peptide T, one before and one after 12 wk of treatment w

40 Exposure of psoriatic fibroblasts to peptide T resulted in a time (4 h to 6 d) and dose [10(-

41 insight into the noted beneficial effects of peptide T treatment, including an improvement in psoriat

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