ライフサイエンスコーパス: peptide antibiotic

1 local expression of this antistaphylococcal peptide antibiotic.

2 a gene-encoded, posttranslationally modified peptide antibiotic.

3 elerate rational engineering of nonribosomal peptide antibiotics.

4 ly synthesized, posttranslationally modified peptide antibiotics.

5 e involved in the synthesis of polyketide or peptide antibiotics.

6 ed to the polyoxin and nikkomycin nucleoside-peptide antibiotics.

7 esent a large family of ribosomally produced peptide antibiotics.

8 ynthesized and post-translationally modified peptide antibiotics.

9 Lantibiotics are a unique class of peptide antibiotics.

10 pproach to make carbohydrate-modified cyclic peptide antibiotics.

11 human beta-defensins and the design of novel peptide antibiotics.

12 an attractive approach for developing novel peptide antibiotics.

13 n effective approach for preparing selective peptide antibiotics.

14 de a useful template for the design of novel peptide antibiotics.

15 re the best characterized epithelial-derived peptide antibiotics.

16 foundation for the structure-based design of peptide antibiotics.

17 e reductase inhibitor, an oxazolidinone, two peptide antibiotics, a glycylcycline, and a peptide defo

18 osynthetic genes for this subclass of uridyl peptide antibiotics and provide the basis for future mec

19 eptide synthetase (NRPS) proteins to produce peptide antibiotics and siderophores.

20 D-amino acids are commonly found in peptide antibiotics and the cell wall peptidoglycan of b

21 g peptide antitumor agents, hormones, cyclic peptide antibiotics, and model proteins.

22 well as in the biosynthesis of menaquinone, peptide antibiotics, and peptide siderophores.

23 a large number of candidate drugs, including peptides, antibiotics, and chemotherapeutic agents.

24 Membrane-permeabilizing peptide antibiotics are an underutilized weapon in the b

25 Natural peptide antibiotics are part of host innate immunity aga

26 Peptide antibiotics are viable alternatives although the

27 entify the thiocillins, a group of thiazolyl peptide antibiotics, as biofilm matrix-inducing compound

28 responsible for the synthesis of the cyclic peptide antibiotic Aureobasidin A (AbA) in Aureobasidium

29 n (a single peptide lantibiotics), and three peptide antibiotics (bacitracin, polymyxin B, and vancom

30 uences and will open prospects for designing peptide antibiotics, biosensors, and new membrane protei

31 intermediates suggest a general strategy in peptide antibiotic biosynthesis.

32 ants of the thiocillin subclass of thiazolyl peptide antibiotics by a cascade of post-translational m

33 In nonribosomal biosynthesis of peptide antibiotics by multimodular synthetases, amino a

34 into microbial secondary metabolism to form peptide antibiotics by specific oxidation, including hyd

35 A member of another family of peptide antibiotics called cathelicidins recently was id

36 cal isolates of Streptococcus mutans produce peptide antibiotics called mutacins.

37 synthesis of the tuberculostatic macrocyclic peptide antibiotic capreomycin IB has been accomplished.

38 Extracellular secretion of the peptide antibiotic colicin V (ColV) in Escherichia coli

39 amily and is essential for the export of the peptide antibiotic colicin V.

40 They are members of another class of peptide antibiotics containing aspartate, which when pre

41 ynthesized and post-translationally modified peptide antibiotics containing the characteristic thioet

42 mammalian skin expresses these gene-encoded peptide antibiotics during inflammatory events such as w

43 for the bis-intercalative interaction of the peptide antibiotic echinomycin with DNA.

44 hicin represents a hydrophobic alpha-helical peptide antibiotic forming voltage-gated ion channels in

45 The human HNP-defensin-1 gene encodes a peptide antibiotic found exclusively in neutrophils and

46 factor (EF) Tu-GDP and the cyclic thiazolyl peptide antibiotic, GE2270A, has been determined by X-ra

47 ructural approaches, we show that the cyclic-peptide antibiotic GE23077 (GE) binds directly to the ba

48 ical protein PacB, conserved in known uridyl peptide antibiotics gene clusters, has been characterize

49 The non-ribosomal synthesis of the cyclic peptide antibiotic gramicidin S is accomplished by two l

50 eration of a host of D-amino acid-containing peptide antibiotics (gramicidin, actinomycin, bacitracin

51 Peptide antibiotic (halocin) preparations from euryarcha

52 or laspartomycins, a family of 11 amino acid peptide antibiotics, has been cloned and sequenced from

53 of cationic steroid antibiotics and cationic peptide antibiotics have been compared.

54 Whereas peptide antibiotics have been reported from bacillus spe

55 Previous studies have implicated the novel peptide antibiotic human beta-defensin 1 (hBD-1) in the

56 vivo are shown to constitutively express the peptide antibiotic human beta-defensin type 1 (hBD-1).

57 orial biosynthesis platform to produce novel peptide antibiotics in sufficient quantities for antimic

58 structural diversity of the amphomycin-group peptide antibiotics including the laspartomycins and fri

59 Polymyxin B (PMB), a cyclic, cationic peptide antibiotic, inhibits biological activities of LP

60 ovide templates for designing broad-spectrum peptide antibiotics intended to function in extracellula

61 Synthetic peptides modeled after natural peptide antibiotics interfere with microbial membranes a

62 ring a gene encoding a secreted cathelicidin peptide antibiotic into the airway epithelium grown in a

63 nsiderable number of ribosomally synthesized peptide antibiotics involves the modification of Ser and

64 This peptide antibiotic is unique since it is processed from

65 Polymyxin B, a cationic peptide antibiotic, is one of the simplest molecules cap

66 Synthetic peptide antibiotics may be useful tools in the search fo

67 In many peptide antibiotics, modified amino acids are important

68 Thiazolyl peptide antibiotic nocathiacin I (1) was converted to no

69 est that the same process used in assembling peptide antibiotics or a yet unidentified mechanism may

70 lmonella enterica controls resistance to the peptide antibiotic polymyxin B and to several antimicrob

71 nella typhimurium controls resistance to the peptide antibiotic polymyxin B and to several antimicrob

72 henotypes with respect to sensitivity to the peptide antibiotic polymyxin B: classical strains are se

73 Bacitracin is a widely used metal-dependent peptide antibiotic produced by Bacillus subtilis and Bac

74 oesterase, and to create a library of cyclic peptide antibiotic products.

75 The peptide antibiotic ramoplanin inhibits bacterial peptido

76 ntibiotics suggest that cationic steroid and peptide antibiotics share mechanistic aspects.

77 acking glycolipids are more sensitive to the peptide antibiotic sublancin and are defective in swarmi

78 rent substructure of polycyclic nonribosomal peptide antibiotics such as vancomycin.

79 efensin 3 (hBD-3) is an inducible epithelial peptide antibiotic that has potent antistaphylococcal ac

80 Cathelicidins are a class of small cationic peptide antibiotics that are expressed in skin and in ot

81 beta-defensins are endogenous cysteine-rich peptide antibiotics that are produced either by epitheli

82 Mutacin 1140 and nisin A are peptide antibiotics that belong to the lantibiotic famil

83 Lantibiotics are a class of peptide antibiotics that contain one or more thioether b

84 Pacidamycins are a family of uridyl peptide antibiotics that inhibit the translocase MraY, a

85 imics incorporate features of the nucleoside-peptide antibiotics, the polyoxins and the nikkomycins,

86 the response of Streptomyces lividans to the peptide antibiotic thiostrepton, and lesser sequence sim

87 aminobutanoic acid (DAB) is found in several peptide antibiotics, toxins, and biologically active mol

88 The uridyl peptide antibiotics (UPAs), of which pacidamycin is a me

89 IV (2) are novel indole-containing thiazolyl peptide antibiotics, which exhibit potent activity again

90 lly encoded and posttranslationally modified peptide antibiotics, which inhibit the growth of other G

91 ctionalized with polymyxin B (PMB), a cyclic peptide antibiotic with high affinity for LPS.

92 tion of the charge cluster of an amphipathic peptide antibiotic with microbial membranes is a salt-se