ライフサイエンスコーパス: peptide chain

1 en tyrosine was located in the middle of the peptide chain.

2 ports a key role for each residue within the peptide chain.

3 preserve the recognized conformation of the peptide chain.

4 f two loops connected by a flexible U-shaped peptide chain.

5 galectin that also has two CRDs in a single peptide chain.

6 tion of the glycosyl amino acid units into a peptide chain.

7 incorporated at any desired position of the peptide chain.

8 ranslation and the rate of elongation of the peptide chain.

9 slocase requirement for translocation of the peptide chain.

10 ipid chain and a coumarin fluorophore in the peptide chain.

11 s only a small degree of variation along the peptide chain.

12 Leu] at a single, unique, position along the peptide chain.

13 reaction between two terminal olefins on the peptide chain.

14 orporation of an amino acid into the growing peptide chain.

15 ll elongation at specific sites within their peptide chain.

16 epimerization of stereogenic centers in the peptide chain.

17 trands that are cross-linked through pendant peptide chains.

18 integrity depends on the intertwining of two peptide chains.

19 ength, suggesting a lateral packing of three peptide chains.

20 tif with a one-amino-acid offset between the peptide chains.

21 anonical offset of four residues between the peptide chains.

22 so affect fibrillogenesis and folding of the peptide chains.

23 a bundle of k adhering parallel polyglycine peptide chains.

24 to involve residues His-6 and His-14 of both peptide chains.

25 brils by reducing repulsions between amyloid peptide chains.

26 causes cotranslational scission of emerging peptide chains.

27 ed by processive enzymes and cross-linked by peptide chains.

28 onserved and primary modification of nascent peptide chains.

29 ctional groups at the N-termini of poly-beta-peptide chains.

30 Two distinct peptide chains (A and B) were synthesized to model a sit

31 regation number is varied between k = 2 (two peptide chains adhering to each other with plenty of wat

32 eta(1-42) peptide chain to mitigate on-resin peptide chain aggregation, a presumed major source of sy

33 roup and the energy required to fragment the peptide chain allows the O-GlcNAc group to be detected a

34 proteins by ligating labelled and unlabelled peptide chains allows one to filter out unwanted informa

35 homogeneous NMP solutions by elongating the peptide chain alone the N-terminus.

36 The combination of a long peptide chain along with the chromophore unit of PVD gen

37 ant calprotectin, consisting of 2 individual peptide chains also called migration inhibitory factor-r

38 he number of amino acid residues in the main peptide chain; amino acid residues attached to sulfur ar

39 cting domain pairs that are part of the same peptide chain and thus have an inter-domain peptide regi

40 a-amino acid can be controlled by the chiral peptide chain, and at the beta-position by using chiral

41 ar to assist in the expulsion of the growing peptide chain, and clamps at the ends of the mRNA tunnel

42 double-Gly(24)/Met(27) substitutions in the peptide chain, and compare their performance in GRPR-pos

43 ed by its application to the ligation of two peptide chains, and the generation of peptides with seve

44 ulky leucine side chain at position 3 in the peptide chain appears to play a role in the conformation

45 When the peptide chains are attached to the two different termini

46 m in which the C-terminally located DeltaPol peptide chains are cleaved intermolecularly to release t

47 ted with polysomes and the newly synthesized peptide chains are closely associated with molecular cha

48 And finally, the cross-linked peptide chains are dissociated from each other, and each

49 (MeDbz) moiety that enables in a more robust peptide chain assembly.

50 be removed, allowing the prolongation of the peptide chain at the C-terminus.

51 ces between the unfolded states of even long peptide chains, at variance with expectations based on a

52 cients proved to be nearly uniform along the peptide chain, averaging to D = 0.49-0.55 x 10(-6) cm(2)

53 n (grp) 170, have shown them to be efficient peptide chain-binding proteins.

54 ystallographically independent copies of the peptide chain, both at the receptor-binding site and els

55 nal modifications included elongation of the peptide chain by three residues at the N-terminus, its a

56 ndered amino acids have been introduced into peptide chains by coupling N-(Cbz- and Fmoc-alpha-aminoa

57 iological activity without preorganizing the peptide chains by covalent linkages.

58 pha-inhibitor (IalphaI, containing one light peptide chain called bikunin and two heavy chains) and p

59 Peptide chains can be cleaved selectively on the N-termi

60 cted determinants, most likely by creating a peptide chain cleavage in the antigenic molecule.

61 Further assembly of the peptide chain, cleavage from the resin using 2-5% TFA in

62 riazene linkage, on-resin cyclization of the peptide chain, cleavage of the cyclic peptide from the r

63 Synthesis of a 119-residue peptide chain containing 10 residues of the reverse tran

64 ides provides a novel strategy for accessing peptide chains containing unnatural vinyl glycine amino

65 abase contains over 5000 representative poly-peptide chains, covering all known structures in the PDB

66 es, indicators for N-terminal, C-terminal or peptide chain cross-link modifications, keywords, litera

67 luding amino-terminal, carboxyl-terminal and peptide chain cross-link modifications.

68 cations including N-terminal, C-terminal and peptide chain cross-link modifications.

69 ies; indicators forN-terminal, C-terminal or peptide chain cross-link modifications; keywords; and li

70 A is a D,d-endopeptidase able to cleave most peptide chain cross-links in V. cholerae's PG.

71 ete 180 degrees turn in the direction of the peptide chain define a reverse turn, a common motif and

72 lete 180 degree-turn in the direction of the peptide chain, define the beta-turn.

73 -like conformation with two loosely extended peptide chains, demonstrating the preference of the sequ

74 r a general hydrophobic collapse of the poly peptide chain driven by the change in solvent conditions

75 the stem plays an important role in securing peptide chains during translocation.

76 Peptide chain elongation as measured by polymerization o

77 Anti-EF-Tu antibodies similarly inhibit peptide chain elongation by P. aeruginosa ribosomes in t

78 chanism and performing the first step in the peptide chain elongation cycle.

79 Two independent methodologies show that the peptide chain elongation rate increases as a function of

80 Temperature shift experiments show that peptide chain elongation rate increases immediately, whi

81 tidyl transferase activity, a key enzyme for peptide chain elongation, was also significantly decreas

82 n to inhibit protein translation by reducing peptide chain elongation.

83 ther mobilized ER-associated Ca2+ nor slowed peptide chain elongation.

84 protein synthesis by controlling the rate of peptide chain elongation.

85 and they all showed reduced in vivo rates of peptide-chain elongation and increased levels of precurs

86 s associated with stimulation of the rate of peptide-chain elongation.

87 g" markedly increased the conductance of the peptide chain, especially when its location in the seque

88 L-Ala/D-Ala replacement in the middle of the peptide chain exhibited much higher diastereomeric resol

89 nd GTP as the essential energy ingredient in peptide chain extension all appeared from our laboratory

90 on by light of the diastereoselectivity of a peptide chain extension reaction.

91 ame on tmRNA that tags the defective nascent peptide chain for degradation.

92 y, partially unfolded state where one of the peptide chains forms a solvent-exposed loop.

93 cle into the growing polyketide/nonribosomal peptide chain from the precursors malonyl-CoA and cystei

94 The force-induced desorption of single peptide chains from mixed OH/CH(3)-terminated self-assem

95 sidues at positions 1 and 4, produced during peptide chain growth from L-Phe residues by 50 kDa epime

96 acidic, heat-stable sialoglycopeptide whose peptide chain has 100% homology to the putative sixth tr

97 lidine-type pseudoprolines (CF3-PsiPro) into peptide chains have been studied.

98 a disordered micellelike collection of a few peptide chains held together loosely by hydrophobic inte

99 raction by increasing the flexibility of the peptide chain; hence, the transition state would be dest

100 or incorporating multidentate ligands onto a peptide chain in a site-specific fashion.

101 phase, amino acids are added to the nascent peptide chain in accordance with codon sequences in the

102 ld statherin, starting from a fully extended peptide chain in solution, in the presence of hydroxyapa

103 C terminus may result in the bending of the peptide chain in such a way that these two peptides come

104 etween the stalling of the elongated nascent peptide chain in the ribosome and its insertion through

105 ciculin reducing the segmental motion of the peptide chain in this local region.

106 dicating a parallel alignment of neighboring peptide chains in the predominantly beta-sheet structure

107 ecause of a single amino acid offset between peptide chains in the triple helix, distinct heterotrime

108 Here, the method is extended to peptide chains in vacuum.

109 ine residues at specific locations along the peptide chain, in both the C-terminal and N-terminal dom

110 wn to play important roles in the eukaryotic peptide chain initiation process.

111 ing amino acid sufficiency to the control of peptide chain initiation.

112 er of mRNA species, the incorporation of the peptide chain into microsomes, and the topology of the p

113 cifically hydroxylates proline residues in a peptide chain into R-4-hydroxyproline, which is essentia

114 ly involves physical partitioning of nascent peptide chains into the lipid bilayer.

115 tain friction forces as a single polyglycine peptide chain is pulled out of a bundle of k adhering pa

116 a disulfide bond near the middle of a short peptide chain is sufficient to nucleate some antiparalle

117 of as an alpha-carbon representation of the peptide chain, is a caricature of the sequence designed

118 esidue glycine, to investigate the effect of peptide chain length on the appearance of macrocycle fra

119 specific amino acids nor a specific nascent peptide chain length was required for AAP to inhibit PTC

120 ediate, k(2), shows a dramatic dependence on peptide chain length, the rate constant for the intermed

121 ukin 5 (wt IL5) is composed of two identical peptide chains linked by disulfide bonds.

122 annel, we propose that cleavage of the IP3 R peptide chain may alter other important regulatory event

123 tation have been investigated in an isolated peptide chain model (N-acetylphenylalaninylamide, NAPA)

124 The incorporation into a peptide chain of highly hindered and weakly nucleophilic

125 yclic depsipeptide in contrast to the linear peptide chain of P39167-I and PA225-I.

126 Finally, the peptide chain of the resulting support-bound S-linked gl

127 friction forces for the relative sliding of peptide chains of Araneus diadematus spider silk within

128 cifically whether it can begin while nascent peptide chains of individual subunits are still attached

129 ndicates a preferred orientation between the peptide chains of the dimers.

130 Both alpha and beta peptide chains of the human leukocyte antigen-DQ heterod

131 IFN-gamma SC1 was derived by linking the two peptide chains of the IFN-gamma dimer by a seven-residue

132 ons arises from the lack of hydration of the peptide chain on either side of the bulky aromatic side

133 tase has a limited capacity to translocate a peptide chain on its own.

134 ated with aqueous ammonia, which cleaved the peptide chain on the N-terminal side of cyanylated cyste

135 n(Mtt)-OH can be incorporated into a growing peptide chain on Wang resin.

136 eneral synthetic methods for the grafting of peptide chains onto polyoxometalate clusters by the use

137 nylation is the addition of prenyl groups to peptide chains or metabolites via the condensation of ge

138 d provide a model for controlled assembly of peptide chains or segments of larger proteins.

139 terns from single nanocrystals show that the peptide chains pack in parallel cross-beta columns with

140 the dimensions of beta-sheets with extended peptide chains perpendicular to the long axis of the agg

141 These data suggest that the growing peptide chain plays a role in modulating fluctuations be

142 resent at the adhesion sites) and k = 7 (one peptide chain pulled out from a close-packed cylindrical

143 mmunofluorescence microscopy or alpha 1 (IV) peptide chain quantitation by Western analysis and the a

144 We have determined the crystal structure of peptide chain release factor 1 (RF1) from Thermotoga mar

145 20480, that encode two predicted proteins, a peptide chain release factor 1 and a hemolysin acyltrans

146 2 into the 5' end of prfC, the gene encoding peptide chain release factor 3.

147 w that on partitioning into the bilayer, the peptide chains remain in contact with lipid headgroups.

148 ective MS/MS conditions, and the dissociated peptide chains remained intact during MS(2), thus enabli

149 escent tag is cleaved off from the substrate peptide chain resulting in an approximately 100-fold inc

150 tamyl)lysine cross-links, connecting various peptide chain segments, are frequently the major product

151 This study shows that folding is rapid and peptide chain self-cleavage occurs early for subunits ad

152 ssible steps take place at the center of the peptide chain; subsequently, several pathways appear to

153 The hydrophobic structure of the peptide chains suggests that they act as symmetric deter

154 d in several translational events, including peptide chain termination and decoding accuracy.

155 nucleotide 1054 are the result of defects in peptide chain termination rather than of decreases in ge

156 in one or more specific interactions during peptide chain termination.

157 cific interaction of the loop is involved in peptide chain termination.

158 sion is limited by release factor-1-mediated peptide chain termination.

159 methionine sixth heme ligand and the nearby peptide chain that has been implicated in electron trans

160 tic molecular dynamics simulations for short peptide chains that are laterally pulled over planar hyd

161 Specifically, the four peptide chains that comprise the filter adopt an unusual

162 Considering the unusual peptide chain, the elucidation of the structure presente

163 ydrogen bond to primary binding sites on the peptide chains, the enthalpy was approximately constant

164 istance between interacting atoms on vicinal peptide chains thereby increasing the electrostatic inte

165 erine, and alanine residues in the middle of peptide chains, thereby providing a biochemical capabili

166 Attachment of a growing peptide chain to a glycylaminomethyl resin via a thiogly

167 ise solid-phase assembly of the A beta(1-42) peptide chain to mitigate on-resin peptide chain aggrega

168 the same steps as those of natural collagen (peptide chain to triple helix to nanofibres and, finally

169 of the TREN scaffold which allows the three peptide chains to adjust their register for a tighter tr

170 The tendency of peptide chains to aggregate is translated into a list of

171 ons are performed on a system of eight model peptide chains to study how the competition between prot

172 Analysis of the heme group arrangement and peptide chain topology of RoxA confirmed a distant kinsh

173 The remaining part of the peptide chain was modeled as a mixture of three sequence

174 iency by secondary structures of the nascent peptide chain, we performed a comparative analysis in ba

175 This growing peptide chain wends its way through the ribosomal tunnel

176 The extended conformations of the peptide chains were confirmed by 1D and 2D NMR.

177 tion, and Fourier transform IR suggested the peptide chains were in a parallel (AcVYK, AcPHF6) or ant

178 ovement of the helix/coil boundary along the peptide chain, which leads to slower unfolding kinetics

179 en bonds with the backbone of the subsequent peptide chain, while lysine and glutamine less frequentl

180 d distances in this core region of the Abeta peptide chain with solid-state NMR.

181 d radius 2.30+/-0.05 nm surrounded by 49+/-4 peptide chains with a partial specific volume of 0.7 cm3

182 -packed cylindrical array of six neighboring peptide chains with no water inside the bundle).

183 well defined composition and register of the peptide chains within the helix, based on information en

184 elf-solvated globule conformation, where the peptide chain wraps around and solvates the charge locat