ライフサイエンスコーパス: peptide transporter

1 thers empty MHC class I molecules to the TAP peptide transporter.

2 induced by carbon starvation and to encode a peptide transporter.

3 lex between the class I molecule and the TAP peptide transporter.

4 r of PTR2, a gene encoding the transmembrane peptide transporter.

5 ytes, confirming the function of HvPTR1 as a peptide transporter.

6 y, the peptides nevertheless are absorbed by peptide transporters.

7 ow TAP1 expression and a reduced function of peptide transporters.

8 eported guanidinium-rich oligocarbonates and peptide transporters.

9 ate studies on the regulatory aspects of the peptide transporters.

10 ly elucidated primary structure of mammalian peptide transporters.

11 In Antarctic icefish (Chionodraco hamatus) peptide transporter 1 (PEPT1), the first transporter clo

12 AAs, respectively) and induced expression of peptide transporter 1 (PEPT1).

13 interferon-induced genes, and the ER antigen peptide transporter 1 (TAP1).

14 The human peptide transporter 2 (PEPT2) expressed by proximal tubu

15 Here we demonstrated that Slc15a1, a peptide transporter also known as Pept1, was predominant

16 lize the structural segments stabilizing the peptide transporter and investigated which of these stru

17 indicated that DtpD functions as a canonical peptide transporter and is, therefore, a valid model for

18 ion of a subset of genes, including the TAP1 peptide transporter and proteasome subunit beta type 9 (

19 ate genes encode an extensin-like protein, a peptide transporter and two unknown proteins, which may

20 ession of TAP, the MHC-encoded cytosol to ER peptide transporter, and (iii) was blocked by pinocytosi

21 oteins expressed in the ovary: opt1, a novel peptide transporter, and nod, a member of the kinesin fa

22 lts show that tapasin links Qa-1b to the TAP peptide transporter, and that tapasin facilitates the de

23 e CUP9-TUP1-SSN6 repressor complex, the PTR2 peptide transporter, and the UBR1-dependent N-end rule p

24 a member of the oligopeptide (OPT) family of peptide transporters, and a recessive mutant allele, opt

25 tation in the gene encoding subunit 1 of the peptide transporter associated with antigen processing (

26 In human B lymphoblasts, inhibition of the peptide transporter associated with antigen processing (

27 that tethers empty class I molecules to the peptide transporter associated with antigen processing (

28 yed 58% identity to the Arabidopsis thaliana peptide transporter AtPTR2-B.

29 APPROACH: A peptide transporter comprising sixteen lysine residues a

30 The heterodimeric peptide transporter consists of two homologous subunits,

31 rast, several citric-acid cycle enzymes, the peptide transporter CstA, PEB1 aspartate/glutamate trans

32 wo approaches were taken to characterize the peptide transporter defect in this mutant strain.

33 "Empty" HLA-Cw7 expressed in peptide transporter-deficient cells and HLA-Cw7 loaded w

34 t presented to CD8+ T cells via a proteasome/peptide transporter-dependent pathway.

35 One laboratory has reported that the peptide transporter encoded by the Tap1 gene within H2g7

36 r the catalytic function of the H(+)-coupled peptide transporters expressed in the intestine and the

37 Arabidopsis thaliana nitrate transporter 1/peptide transporter family (NPF) 6.3 is a dual-affinity

38 xylem loading from the Nitrate transporter 1/Peptide Transporter family (NPF2.4).

39 is study, PEPT2 is the primary member of the peptide transporter family responsible for dipeptide upt

40 of the Lotus japonicus nitrate transporter1/peptide transporter family, LjNPF8.6 The phenotypic char

41 scherichia coli, a prokaryotic member of the peptide transporter family.

42 the first structural view of a member of the peptide transporter family.

43 (Arabidopsis thaliana) NITRATE TRANSPORTER1 PEPTIDE TRANSPORTER FAMILY6.3.

44 for Medicago truncatula NITRATE TRANSPORTER1/PEPTIDE TRANSPORTER Family6.8) in the inhibition of prim

45 diated intestinal absorption, via the hPEPT1 peptide transporter, followed by the rapid and complete

46 rly characterized family of peptide/modified peptide transporters found in archebacteria, bacteria, f

47 milar prokaryotic homologue of the mammalian peptide transporters from Shewanella oneidensis.

48 Comparison with peptide transporters further reveals how the NRT1/PTR fa

49 mino acids or short peptides up-regulate the peptide transporter gene PTR2, thereby increasing the ca

50 ave shown increased frequency of alleles for peptide transporter genes TAP1 (0101) and TAP2 (0101) ge

51 ein, a plant peptide hormone, and many OLIGO PEPTIDE TRANSPORTER genes, all of which may lead to indu

52 In addition, the peptide transporters have immediate pharmacologic releva

53 -L-glutamine (Gly-Gln) of the proton-coupled peptide transporter, hPepT1, in the Caco-2 human intesti

54 o understand further the purpose of specific peptide transporters in brain, we have generated PEPT2-d

55 iously reveal, as illustrated by examples of peptide transporters in Escherichia coli and nitrogenase

56 Expression of the PTR2 peptide transporter is induced not only by amino acids b

57 One candidate for an alternative peptide transporter is P-glycoprotein, which transports

58 In contrast, structural information on peptide transporters is very sparse.

59 tein Mdl1 was identified as an intracellular peptide transporter localized in the inner membrane of y

60 Proton-coupled peptide transporters mediate the absorption of a large v

61 multiple proteases and toxins, and iron- and peptide-transporter molecules, which are upregulated in

62 omimetics that might specifically target two peptide transporters (namely, PEPT1 and PEPT2) upregulat

63 ed protein response, and inhibition of a gut peptide transporter partially suppressed C. elegans resp

64 was found to be negatively regulated by the peptide transporter PEPT-1, as well as the target of rap

65 Two peptide transporters, PEPT 1 and PEPT 2, have been clone

66 colonic mucosal growth and expression of the peptide transporter PepT1 in adults with or without SBS.

67 sh border enzyme dipeptidyl peptidase IV and peptide transporter PepT1 messenger RNA levels were dete

68 tide derivatives by the mammalian intestinal peptide transporter PepT1 were investigated, using the X

69 The intestinal H(+)-coupled peptide transporter PepT1, displays a broad substrate sp

70 N2 were good substrates for the H(+)-coupled peptide transporters PEPT1 and PEPT2.

71 are conserved among the intestinal and renal peptide transporters (PEPT1 and PEPT2, respectively) fro

72 tic analysis of the rat kidney high-affinity peptide transporter PepT2 expressed in Xenopus oocytes.

73 ic G protein-coupled receptor (beta2AR), the peptide transporter (PepTSt), diacylglycerol kinase (Dgk

74 solution structural studies of the bacterial peptide transporter PeptTSo2 by single-particle cryo-ele

75 epT1 and PepT2, the mammalian proton coupled peptide transporters (POTs), function to assimilate and

76 mpaired in macrophages deficient in PepT1, a peptide transporter previously implicated in MDP interna

77 pecific homolog of protein phosphatase 2C, a peptide transporter protein, and a nodule-specific form

78 antigen loss, and (b) downregulation of the peptide-transporter protein TAP-1 expression by this pat

79 al, low-affinity Nitrate Transporter1 (NRT1)/Peptide Transporter (PTR) family member NPF7.3/NRT1.5 is

80 unbiased visual screen, which identified the peptide transporter Ptr2 and the ammonium permease Mep3

81 ets CUP9, a transcriptional repressor of the peptide transporter PTR2, through an internal (non-N-ter

82 of Cup9, a transcriptional repressor of the peptide transporter Ptr2.

83 Peptide transporters (PTRs) of the large PTR family faci

84 urease, iron uptake systems, amino acid and peptide transporters, pyruvate metabolism enzymes, and a

85 Here we show that two endo-lysosomal peptide transporters, SLC15A3 and SLC15A4, are preferent

86 (SGK) and the proteasome-associated antigen peptide transporter subunit 1 (Tap1), was confirmed afte

87 EBV miRNAs directly target the peptide transporter subunit TAP2 and reduce levels of th

88 his study provides new evidence for multiple peptide transporter systems in Arabidopsis, suggesting a

89 lbumin secreted by the parasite requires the peptide transporter TAP (transporter associated with ant

90 epsin-positive amphisomal vacuoles, to which peptide transporter TAP and upregulated MHC class I (MHC

91 al processing components like proteasome and peptide transporter TAP.

92 lass I chains from the ER, inhibition of the peptide transporter (TAP) involved in antigen presentati

93 bility Complexes (MHCs) and to Transmembrane Peptide Transporter (TAP), as well as an annotated list

94 res formation of a complex between the 'ABC' peptide transporter, TAP, and newly synthesized class I

95 , fungi, and bacteria they are predominantly peptide transporters, whereas in plants the family has d

96 Here, we report creation of a 36-amino acid peptide transporter, which can transport a protein to th