ライフサイエンスコーパス: peptidoglycan

1 than hydrolases, but they do not cross-link peptidoglycan.

2 e periplasm, a compartment that contains the peptidoglycan.

3 OmpA show a propensity to form contacts with peptidoglycan.

4 shed roles in sensing fragments of bacterial peptidoglycan.

5 sure and opportunity to reduce the levels of peptidoglycan.

6 of galactofuranose (Galf) residues linked to peptidoglycan.

7 teria via binding to the bacterial cell wall peptidoglycan.

8 or components and possible interactions with peptidoglycan.

9 osophila S2* cells stimulated with bacterial peptidoglycan.

10 ated (PASTA) domains, and binds fragments of peptidoglycan.

11 directs an invaginating annulus of cell wall peptidoglycan.

12 nsfer the primary epsilon-amine of lysine to peptidoglycan.

13 ic enzyme (PG-lytic enzyme) to locally clear peptidoglycan.

14 ursors to the cell surface for attachment to peptidoglycan.

15 hitin, chitosan, and acetylxylan, but not on peptidoglycan.

16 microbial PAMPs including flagellin, LPS and peptidoglycan.

17 te immune receptors that recognize microbial peptidoglycans.

18 We show that O-acetylation of peptidoglycan, a mechanism utilized by S. aureus to bloc

19 We found that CwlM, a protein homologous to peptidoglycan amidases, coordinates peptidoglycan synthe

20 ecognition of diaminopimelic acid (DAP)-type peptidoglycan and activation of the NF-kappaB precursor

21 ng that this amino sugar is released through peptidoglycan and chitin decomposition and serves as an

22 ites, including the unknown contributions of peptidoglycan and chitin decomposition to soil organic N

23 GAC is covalently attached to peptidoglycan and consists of a polyrhamnose polymer, wi

24 he largest changes in protein abundance were peptidoglycan and fatty acid (FA) synthesis, translation

25 ion of robust and mature MurNAc O-acetylated peptidoglycan and infer its role in the division of the

26 ject of many studies because of its roles in peptidoglycan and O-antigen biosynthesis.

27 glycan labeling, the prevalence of microbial peptidoglycan and preservation of microbial surface land

28 biosynthesis of phospho-sugars, nucleobases, peptidoglycan and some amino acids.

29 e polyketide sugar unit, lipopolysaccharide, peptidoglycan and terpenoid backbone pathways.

30 s, the PBPs incorporate lysine into cellular peptidoglycan and that, further, the PBPs have the unpre

31 ft connected to the rotor passes through the peptidoglycan and the outer membrane through bushings, t

32 -positive bacteria contains equal amounts of peptidoglycan and the phosphate-rich glycopolymer wall t

33 J contains a LysM domain that interacts with peptidoglycan and thus assists its localization into the

34 nt with amphomycin's dual inhibition of both peptidoglycan and wall teichoic acid biosyntheses in S.

35 ylococcus aureus by measuring the changes of peptidoglycan and wall teichoic acid compositions using

36 hesis of a polyisoprenoid essential for both peptidoglycan and WTA synthesis.

37 ly conserved motif of lipid II (precursor of peptidoglycan) and lipid III (precursor of cell wall tei

38 Mycobacterium tuberculosis (Mtb) consists of peptidoglycan, arabinogalactan and mycolic acids.

39 t the 6-position of muramic acid residues in peptidoglycan are essential components of the varphi11 r

40 While many inflammatory responses to peptidoglycan are mediated by detection of its muramyl d

41 B-cell receptors and activation via attached peptidoglycan are the determinants of staphylococcal esc

42 ramphenicol contained a higher percentage of peptidoglycan as cytoplasmic protein content was reduced

43 the major nematode Wolbachia TLR2/6 ligand, peptidoglycan associated lipoprotein, induced NETosis in

44 ponent of the TFP structural complex FimV, a peptidoglycan binding protein, with one of the Chp syste

45 mains: an N-terminal, a cysteine protease, a peptidoglycan-binding and an SH3 bacterial domain.

46 , bacterial derived diaminopimelic acid-type peptidoglycan binds the receptors PGRP-LC and PGRP-LE, w

47 edominantly using D-Ala-D-Lac precursors for peptidoglycan biosynthesis during normal growth supports

48 which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes: alanine racemase and

49 Peptidoglycan biosynthesis is a well-established target

50 Concentrations of peptidoglycan biosynthesis metabolites decreased at 4 hr

51 Notably, peptidoglycan biosynthesis metabolites were significantl

52 resistance mediated by the reprogramming of peptidoglycan biosynthesis to use precursors terminating

53 maintained the incorporation of D-Ala during peptidoglycan biosynthesis while the incorporation of D-

54 se (DHDPS), an enzyme required for bacterial peptidoglycan biosynthesis, catalyzes the condensation o

55 dates that operate through the inhibition of peptidoglycan biosynthesis.

56 ycan precursor lipid II, which could inhibit peptidoglycan biosynthesis.

57 -peptidases that catalyze the final steps of peptidoglycan biosynthesis.

58 the first and an essential membrane step of peptidoglycan biosynthesis.

59 bind and inhibit MurA, which is involved in peptidoglycan biosynthesis.

60 intermediates reserved for re-initiation of peptidoglycan biosynthesis.

61 distinct PBPs and other enzymes involved in peptidoglycan biosynthesis.

62 By hijacking the peptidoglycan biosynthetic machinery, photoaffinity prob

63 The cytoplasmic steps in the peptidoglycan biosynthetic pathway, catalyzed by the Mur

64 tional and localization studies of predicted peptidoglycan biosynthetic proteins in H. neptunium.

65 ycine, to selectively (13)C-(15)N pair label peptidoglycan bridge-link, stem-link, and cross-link, re

66 m was previously reported to completely lack peptidoglycan, but here we present evidence supporting t

67 Recognition of bacterial peptidoglycan by the Drosophila IMD pathway triggers NF-

68 tion of the N-acetylglucosamine component of peptidoglycan by the glycolytic enzyme hexokinase activa

69 ly attach specific bacterial proteins to the peptidoglycan cell wall and are often involved in coloni

70 sion machinery and orchestrates membrane and peptidoglycan cell wall invagination.

71 The peptidoglycan cell wall is a major protective external s

72 The peptidoglycan cell wall is an integral organelle critica

73 In Escherichia coli, the peptidoglycan cell wall is synthesized by bifunctional p

74 Most bacteria possess a peptidoglycan cell wall that determines their morphology

75 Most bacterial cells are surrounded by a peptidoglycan cell wall that is essential for their inte

76 important precursor for the synthesis of the peptidoglycan cell wall, housekeeping proteins, and viru

77 P1A, which aids in the polymerization of the peptidoglycan cell wall, was lethal to LOS-deficient A.

78 b-population of cells generates holes in the peptidoglycan cell wall.

79 s-linking steps in the biosynthesis of their peptidoglycan cell wall.

80 eria are imparted by the structures of their peptidoglycan cell walls, which are determined by many d

81 the non-hydrolytic cleavage of the bacterial peptidoglycan cell-wall polymer.

82 Here, using quantitative microscopy to track peptidoglycan cell-wall synthesis, we found that the Lym

83 ved physical coupling between the OM and the peptidoglycan, cells lost the ability to sense defects i

84 hy and multivariate data analysis to uncover peptidoglycan chemical diversity in the Class Alphaprote

85 tructure, termed the mycolyl-arabinogalactan-peptidoglycan complex, and the phosphatidyl-myo-inositol

86 glycoconjugate, the mycolyl-arabinogalactan-peptidoglycan complex, which has at its core a galactan

87 Peptidoglycan composition and density were maintained af

88 and computational methodology revealed that peptidoglycan composition was approximately maintained a

89 High intravascular peptidoglycan concentration, driven by a higher level of

90 Because PBP2a cannot cross-link peptidoglycan containing monoglycine, this study implica

91 The cell peptidoglycan content and cross-linking were otherwise n

92 treated with fosfomycin exhibited decreased peptidoglycan contributions while those treated with chl

93 first time in this study, which compares the peptidoglycan cross-linking activity of PBP2b from susce

94 MecA induction leads to a reduction in peptidoglycan cross-linking that allows for enhanced deg

95 ed D-Ala in teichoic acids, and reduction of peptidoglycan cross-linking.

96 ht PBPs, which are transpeptidases that form peptidoglycan cross-links, and low-molecular-weight PBPs

97 We find that bacterial cell wall peptidoglycan (CW), a universal PAMP for TLR2, traverses

98 Initial prey entry involves the predator's peptidoglycan DD-endopeptidases, which decrosslink cell

99 These results indicate that peptidoglycan deacetylation plays an important role in m

100 d-Alanine and d-glutamic acid derived from peptidoglycan decomposition exhibited similar turnover r

101 Deleting the deacetylases limits peptidoglycan degradation and rounded prey cell "ghosts"

102 Peptidoglycan degradative enzymes have important roles a

103 octopaminergic neurons and that, a dedicated peptidoglycan degrading enzyme acts in these neurons to

104 Peptidoglycan derivatives activate this response via the

105 ar NOD-like receptor family, sense bacterial peptidoglycan-derived fragments and induce pro-inflammat

106 ture remodeling), which measures subcellular peptidoglycan dynamics.

107 eshift mutation in cjj81176_1105, a putative peptidoglycan endopeptidase.

108 ence sensitivity to Type VI secretion system peptidoglycan endopeptidases and recognition by the Dros

109 cheal cytotoxin (TCT), a monomer of DAP-type peptidoglycan from Bordetella pertussis, causes cytopath

110 essential PBP2b in peripheral elongation of peptidoglycan from the midcells of dividing Streptococcu

111 ropose that rPGRP-LC selectively responds to peptidoglycans from dead bacteria to tailor the immune r

112 oward the inner membrane-bound PBP1A through peptidoglycan gaps and hence regulate the synthesis of p

113 The peptidoglycan glycosyltransferase domain of PBP1b is als

114 The transition from one to three zones of peptidoglycan growth during the cell cycle is also obser

115 The NlpC/p60 peptidoglycan hydrolase activity of SagA is required and

116 tivity of TTPA may reflect the presence of a peptidoglycan hydrolase domain in the alpha-helical regi

117 tions and single nucleotide polymorphisms in peptidoglycan hydrolase genes pgp1 or pgp2 or a reductio

118 pth functional characterization of LytB, the peptidoglycan hydrolase responsible for physical separat

119 ate that during acid stress MarP cleaves the peptidoglycan hydrolase RipA, a process required for Rip

120 IsdP is a specialized peptidoglycan hydrolase that cleaves the stem peptide an

121 cribe engineered triple-acting staphylolytic peptidoglycan hydrolases wherein three unique antimicrob

122 Autolysins and phage lysins are peptidoglycan hydrolases, enzymes that have evolved over

123 Both peptidoglycan hydrolysis and turgor pressure are require

124 Our results suggest that sustaining peptidoglycan hydrolysis, a process required for cell el

125 f the thickness, composition and location of peptidoglycan in K. stuttgartiensis, we propose to redef

126 adation of Gram-positive bacterial cell wall peptidoglycan in macrophage and dendritic cell phagosome

127 the chemical composition and organization of peptidoglycan in the domain Bacteria, the real diversity

128 as a hydrolase extension domain and degrades peptidoglycan in the periplasm of target bacteria.

129 outer membrane porin OmpA can interact with peptidoglycan in the presence of Braun's lipoprotein, bu

130 es asymmetrically, accompanied by asymmetric peptidoglycan incorporation and short FtsZ-like filament

131 In addition, some peptidoglycan incorporation occurs along the cell body,

132 -stress-induced inflammatory responses via a peptidoglycan-independent mechanism.

133 ponents of its cell wall, but was not due to peptidoglycan-induced IL-10 production.

134 AR reveals that CrvA asymmetrically patterns peptidoglycan insertion rather than removal, causing mor

135 st that FTT_0924 is required for maintaining peptidoglycan integrity and virulence.

136 The signature gene set of the peptidoglycan-intermediate group reveals insights into m

137 is, we have identified a group of predicted 'peptidoglycan-intermediate' organisms that includes the

138 Peptidoglycan is a fundamental structure for most bacter

139 The peptidoglycan is a rigid matrix required to resist turgo

140 The peptidoglycan is continually remodelled by synthetic and

141 illales species (i.e. lactic acid bacteria), peptidoglycan is decorated by polyrhamnose polysaccharid

142 Recognition of peptidoglycan is integral to detection of gram-positive

143 Peptidoglycan is made of repeating N-acetylmuramic acid

144 Under these conditions peptidoglycan is not necessarily needed to maintain the

145 Peptidoglycan is present in virtually all bacteria, sugg

146 Peptidoglycan is the predominant stress-bearing structur

147 amino sugars and amino acids by hydrolyzing peptidoglycan isolated from isotopically labeled bacteri

148 Peptidoglycan labeling shows that, in this species, buds

149 Given the ease of optical peptidoglycan labeling, the prevalence of microbial pept

150 Importantly, the peptidoglycan labelling enables, for the first time, the

151 4PomA 2PomB, proteins anchored to the rigid peptidoglycan layer of the cell wall.

152 r bacterial prey cells, usually crossing the peptidoglycan layer, forming transient structures called

153 ell periplasm, pausing while it degrades the peptidoglycan layer.

154 width by tethering the outer membrane to the peptidoglycan layer.

155 inimal enzymatic requirements for building a peptidoglycan-like sacculus and/or division septum.

156 esent evidence supporting the existence of a peptidoglycan-like structure in Orientia, as well as an

157 They tend to have reduced amounts of peptidoglycan, likely due to the fact that their growth

158 VH3 expansion occurred with peptidoglycan-linked SpA from the bacterial envelope but

159 ase 2 (RIPK2) was essential for implementing peptidoglycan-linked SpA superantigen activity.

160 l Gly residue of the nascent cross-bridge of peptidoglycan lipid II precursor.

161 nent surface immunomodulatory macromolecules-peptidoglycan, lipopolysaccharide and capsular polysacch

162 were challenged with lipopolysaccharide and peptidoglycan (LPS/PepG).

163 macromolecular machines requires a dedicated peptidoglycan lytic enzyme (PG-lytic enzyme) to locally

164 analysed the occurrence of genes involved in peptidoglycan metabolism across the major obligate intra

165 ell, mediated by the choline-binding domain, peptidoglycan modification, and choline-mediated (lipo)t

166 Peptidoglycan modifying carboxypeptidases (CPs) are impo

167 ical connection between GpsB, PBP A1 and the peptidoglycan modifying enzyme PgdA.

168 within the pgp1 or pgp2 genes, which encode peptidoglycan modifying enzymes.

169 eptibility to lysozyme mainly depends on two peptidoglycan modifying enzymes: The peptidoglycan N-dea

170 r molecule required for the formation of the peptidoglycan monomeric building blocks.

171 on two peptidoglycan modifying enzymes: The peptidoglycan N-deacetylase PgdA and the peptidoglycan O

172 ynthetic pathways including those leading to peptidoglycan, N-linked glycoproteins and lipopolysaccha

173 r, SepJ-related septal junctions, and septal peptidoglycan nanopores.

174 for the translocation of nanomineral-antigen-peptidoglycan (NAP) conjugates to antigen presenting cel

175 can gaps and hence regulate the synthesis of peptidoglycan necessary for bacterial viability.

176 ences in their infection cycle compared with peptidoglycan-negative obligate intracellular bacteria s

177 s study, we have investigated to what extend peptidoglycan O-acetylation is involved in cell wall bio

178 Peptidoglycan O-acetyltransferase B (PatB) catalyzes the

179 fection, and adjuvancy with a staphylococcal peptidoglycan O-acetyltransferase mutant reduces IL-10,

180 The peptidoglycan N-deacetylase PgdA and the peptidoglycan O-acetyltransferase OatA.

181 O-acetylation of peptidoglycan (OAP) is a bacterial phenomenon proposed t

182 s) for synthesis of 4-->3 cross-links in the peptidoglycan of bacterial cell walls.

183 d that the addition of lipopolysaccharide or peptidoglycan of bacterial origin to enterovirus provide

184 hat O-acetylation driven by Adr protects the peptidoglycan of dividing cells from cleavage by the maj

185 of glycopolymers covalently attached to the peptidoglycan of gram positive bacteria.

186 molecular role it plays in attachment to the peptidoglycan of the periplasm is unknown.

187 detect both Gram-positive and Gram-negative peptidoglycans on the bacterial cell walls.

188 the final transfer of the TA chain to either peptidoglycan or a glycolipid.

189 an increased number of nanopores, the septal peptidoglycan perforations that likely accommodate septa

190 The final step of peptidoglycan (PG) biosynthesis in bacteria involves cro

191 It was previously shown to inhibit peptidoglycan (PG) biosynthesis, but its molecular mecha

192 Surprisingly, CwlM is sequestered from peptidoglycan (PG) by localization in the cytoplasm, and

193 tein machineries to synthesize the essential peptidoglycan (PG) cell wall during growth and division.

194 Bacteria are surrounded by a peptidoglycan (PG) cell wall that must be remodeled to a

195 ermined primarily by the architecture of the peptidoglycan (PG) cell wall, a mesh-like layer that enc

196 re, most bacteria surround themselves with a peptidoglycan (PG) exoskeleton synthesized by the penici

197 everely impaired cell separation and altered peptidoglycan (PG) fragment release, but little else is

198 Neisseria gonorrhoeae releases peptidoglycan (PG) fragments during infection that provo

199 his can be achieved by a concerted action of peptidoglycan (PG) hydrolases and PG-synthesizing/modify

200 Peptidoglycan (PG) is a highly cross-linked, protective

201 Peptidoglycan (PG) is important for helical shape, colon

202 in complex with a synthetic cell-wall-based peptidoglycan (PG) ligand that occupies the entire Y-sha

203 es ampC expression in response to changes in peptidoglycan (PG) metabolite levels that occur during e

204 rm the cytokinetic Z-ring, which coordinates peptidoglycan (PG) remodeling and envelope constriction.

205 enterococci (VRE) through the replacement of peptidoglycan (PG) stem terminal d-Ala-d-Ala with d-Ala-

206 oniae (pneumococcus), side-wall (peripheral) peptidoglycan (PG) synthesis emanates from midcells and

207 lance septal and peripheral (side-wall like) peptidoglycan (PG) synthesis in Streptococcus pneumoniae

208 Peptidoglycan (PG), an essential stress-bearing componen

209 ing of a single highly polymeric molecule of peptidoglycan (PG), pose a major problem for the release

210 stsynthetic modifications onto its bacterial peptidoglycan (PG), the coat woven into bacterial cell w

211 l cells are surrounded by a polymer known as peptidoglycan (PG), which protects the cell from changes

212 TolR is related to MotB, the peptidoglycan (PG)-binding stator protein from the flage

213 Modification of essential bacterial peptidoglycan (PG)-containing cell walls can lead to ant

214 um is powered by a proton influx through the peptidoglycan (PG)-tethered stator ring MotA/B.

215 against osmotic lysis by a cell wall made of peptidoglycan (PG).

216 a-D-N-acetylglucosamine (GlcNAc) residues of peptidoglycan (PG).

217 es and dendritic cells upon stimulation with peptidoglycan (PGN, the main cell wall composition of G(

218 ex is functional in the absence of all known peptidoglycan polymerases.

219 te that SEDS proteins constitute a family of peptidoglycan polymerases.

220 This observation identifies a new mode of peptidoglycan polymerization in E. coli that relies on a

221 and discuss its implications with regards to peptidoglycan polymerization.

222 s polymerization of glycan chains, using the peptidoglycan precursor lipid II as a substrate.

223 xperiments show that only LtnA1 binds to the peptidoglycan precursor lipid II, which could inhibit pe

224 ith the lysine of UDP-MurNAc-pentapeptide, a peptidoglycan precursor used by the aminoacyl-transferas

225 alyzes the synthesis of Lipid I, a bacterial peptidoglycan precursor.

226 aring chemical tags or affinity handles into peptidoglycan precursors, including Lipid II, enabling b

227 rk in mammals and senses diaminopimelic-type peptidoglycans present in Gram-negative bacteria.

228 double knockout mice, which cannot recognize peptidoglycan, programmed death-ligand 1 was undetected.

229 Moreover, the presence of peptidoglycan puts bacteria at risk of detection and des

230 live Gram-negative bacteria using the single peptidoglycan receptor PGRP-LC is unknown.

231 at risk of detection and destruction by host peptidoglycan recognition factors and downstream effecto

232 0min, camel alpha-lactalbumin (alpha-la) and peptidoglycan recognition protein (PGRP) were not detect

233 We identified complexes between peptidoglycan recognition protein 1 (PGLYRP1) and bacter

234 Peptidoglycan recognition proteins (PGRPs) are multifunc

235 Mammalian Peptidoglycan Recognition Proteins (PGRPs) kill both Gra

236 The peptidoglycan recognition proteins (PGRPs) PGRP-SB2 and

237 lling ensues in the absence of transmembrane peptidoglycan recognition proteins and the adaptor molec

238 isease is complex and may include defects in peptidoglycan recognition, and/or failures in the establ

239 insights into substrate-binding subsites and peptidoglycan recognition.

240 e that an enzyme thought to be restricted to peptidoglycan recycling is able to disperse preformed bi

241 we show that NagZ, a protein associated with peptidoglycan recycling, has moonlighting activity that

242 We show that peptidoglycan regulates egg-laying rate by activating NF

243 Prey peptidoglycan remains intact for several hours, but is m

244 at will eventually lead to the activation of peptidoglycan remodeling at the forming septum.

245 ies of the molecular mechanisms that control peptidoglycan remodeling in C. crescentus.

246 taining N-acetylmuramyl-L-alanine amidase, a peptidoglycan remodelling enzyme implicated in cell divi

247 poprotein LpoA for constructing a functional peptidoglycan required for bacterial viability.

248 Exogenous application of bacterial peptidoglycans restored phagocytic uptake in the lysosom

249 sidue of the pentapeptide chain of bacterial peptidoglycan, resulting in altered permeability and the

250 roteins, known to decrosslink and round prey peptidoglycan, results in a quadruple mutant Bdellovibri

251 pimelic acid, a ligand for the intracellular peptidoglycan sensor Nod1.

252 Cell wall peptidoglycan stimulates interleukin 10 (IL-10) producti

253 onoglycine), while PBP2a can only cross-link peptidoglycan strands bearing a complete pentaglycine br

254 tive S. aureus transpeptidases to cross-link peptidoglycan strands bearing different glycine branches

255 -chromatographic data sets to discover novel peptidoglycan structural properties in bacteria.

256 Analysis of its peptidoglycan structure revealed a total loss of DAP ami

257 Indeed, chemometric analyses revealed novel peptidoglycan structures conserved in Acetobacteria: ami

258 ssays show that Csd4 can cleave a tripeptide peptidoglycan substrate analog to release m-DAP.

259 on of the structures coinciding with initial peptidoglycan substrate binding to PBP2a, acyl enzyme fo

260 yme formation, and acyl transfer to a second peptidoglycan substrate to attain cross-linking.

261 as potential inhibitors, and in favor of the peptidoglycan substrate.

262 unication and for beta-lactam mimicry of the peptidoglycan substrates, as foundational to the mechani

263 PknB activity is modulated by ECD binding to peptidoglycan substructures, however, the molecular mech

264 ligate intracellular bacteria with classical peptidoglycan such as Coxiella, Buchnera and members of

265 cytoplasmic membrane within bacteria-shaped peptidoglycan surrounded by outer membrane material whic

266 In many Gram-negative bacteria, the peptidoglycan synthase PBP1A requires the outer membrane

267 ng to follow the behaviours of the two major peptidoglycan synthases in live, elongating Escherichia

268 readmilling rate controlled both the rate of peptidoglycan synthesis and cell division.

269 r with other proteins it recruits, it drives peptidoglycan synthesis and constricts the cell.

270 leading edge of the engulfing membrane, with peptidoglycan synthesis and degradation mediated by peni

271 ort dynamic FtsZ filaments can drive initial peptidoglycan synthesis and envelope constriction at the

272 ewborn cells inherit a highly active zone of peptidoglycan synthesis at midcell that contributes to e

273 Thus, FtsN allosterically activates peptidoglycan synthesis by two pathways, one in the cyto

274 At least two parallel pathways impair peptidoglycan synthesis in competent cells.

275 ogous to peptidoglycan amidases, coordinates peptidoglycan synthesis with nutrient availability.

276 (FA metabolism), DD-transpeptidase and MurB (peptidoglycan synthesis), glyoxalase family proteins (re

277 ontrol the activity of enzymes to coordinate peptidoglycan synthesis.

278 absolute, cell length to establish zones of peptidoglycan synthesis.

279 s largely decoupled from the biochemistry of peptidoglycan synthesis.

280 es, such as targeted protein degradation and peptidoglycan synthesis.

281 of FtsZ and FtsA (FtsAZ) that recruit septal peptidoglycan-synthesizing enzymes to the division site.

282 e division ring and drove the motions of the peptidoglycan-synthesizing enzymes.

283 rod-shaped bacteria is mediated by a dynamic peptidoglycan-synthetizing machinery called the Rod comp

284 protein 1 (PGLYRP1) and bacterially derived peptidoglycan that constitute a potent ligand capable of

285 peptidase activity) and the 4,3-cross-linked peptidoglycan (the substrate for the 4,3-endopeptidase a

286 sophila females reduces oviposition and that peptidoglycan, the component that activates Drosophila a

287 physiological activity of cross-linking the peptidoglycan, the major constituent of the bacterial ce

288 ses capable of polymerizing and crosslinking peptidoglycan to build the exoskeletal matrix(1).

289 al probes that facilitate imaging of nascent peptidoglycan to demonstrate that during acid stress Mar

290 ing increasingly smaller concentric rings of peptidoglycan to divide the cell.

291 s and other pathogenic bacteria modify their peptidoglycan to protect it against enzymatic attack thr

292 icating that SLC46As is a conserved group of peptidoglycan transporter contributing to cytosolic immu

293 Loss of Ami1 resulted in defects in septal peptidoglycan turnover with release of excess cell wall

294 The OM is tethered to the peptidoglycan via the lipoprotein, Lpp.

295 sually in the periplasmic region between the peptidoglycan wall and the outer membrane rather than be

296 The peptidoglycan wall, located in the periplasm between the

297 obiont Streptococcus pneumoniae, is bound to peptidoglycan (wall teichoic acid, WTA) or to membrane g

298 inding protein called PBP2a that cross-links peptidoglycan when the native S. aureus PBPs are inhibit

299 essential bacterial processes involving the peptidoglycan, which is unique to bacteria.

300 osed of the large cross-linked macromolecule peptidoglycan, which maintains cell shape and is respons