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1 from 14 New Zealand rabbits were Langendorff-perfused.
5 ion to triggering neuronal depolarization by perfusing a high-K(+) medium from the implanted MD probe
8 rid tip/stalk phenotype that leads to poorly perfused and chaotic angiogenesis, which is a hallmark o
9 med over 4-5 d, after which the tumor can be perfused and extravasation events are easily tracked ove
11 ins in sensory neurons from rats with freely perfused and ligated femoral arteries: peripheral artery
12 on of the 3D postnatal brain vasculature for perfused and nonperfused vessels (e.g., vascular volume
15 ealed that fibroid blood vessels were indeed perfused and stained with the lipophilic membrane dye; h
18 onia, and ex vivo upon treatment of isolated perfused and ventilated lungs with the purified bacteria
20 3% of total B cells) and T cells in elastase-perfused aortas compared with saline-perfused or normal
30 subsequent 6 liver transplants, with livers perfused at lower oxygen tensions, reperfused uneventful
38 ological recordings of fiber conductivity in perfused brain slices, electron microscopy, and immunohi
43 orthotopic position in rat, the grafts were perfused by the recipient's circulation and produced uri
44 ent with the mathematical model, in coronary-perfused canine hearts, the addition of dofetilide (sele
45 picardial and 1 endocardial site of coronary-perfused canine left ventricular wedge preparations, tog
46 epicardial and endocardial sites of coronary-perfused canine RV wedge preparations, together with a p
48 sualization of cryoablation lesions in blood-perfused cardiac muscle preparations and revealed simila
51 facturing methods that contains continuously perfused chambers inhabited by living cells arranged to
56 ine serum and 1% antibiotic-antimycotic) was perfused directly through each scaffold at low flow rate
57 ine serum and 1% antibiotic-antimycotic) was perfused directly through each scaffold at low flow rate
59 studied under conditions suitable for use in perfusing donor organs, namely, under a temperature of 4
61 Here, we developed a vessel-on-a-chip with perfused endothelialized channels lined with human bone
62 tumors grew several times faster, were more perfused, exhibited a two-fold higher mitotic index, and
65 in elimination from the aqueous humor of the perfused eye was reduced 80% when novobiocin (0.1 mM) wa
68 e reperfused with a protective solution then perfused for 4 hours with a novel oxygenated, nutrient-c
69 ed adult mouse hearts or cardiomyocytes were perfused for 5 minutes with the beta-AR agonist isoprote
75 ormed, with (18)F-FDG uptake in the isolated perfused heart verified by gamma counter measurements.
78 isolated cardiac myocytes and in Langendorff-perfused hearts based on the use of the redox-sensitive
80 y in myocardium, but, surprisingly, isolated perfused hearts exhibited higher O2 consumption rates (O
81 METHODS AND We used isolated Langendorff-perfused hearts from control (CTL) and heart failure (HF
86 n establishing single-cell SL in Langendorff-perfused hearts loaded with the membrane dye di-4-ANEPPS
88 and washout, requires the study of isolated perfused hearts to avoid analytic error due to tracer re
90 oablation of either blood-perfused or saline-perfused hearts was associated with a marked decrease in
91 hannels are activated to a greater extent in perfused hearts when the LV performs pressure-volume wor
92 by (31)P magnetic resonance spectroscopy of perfused hearts), and reduced contractility (as measured
98 nd epicardial voltage mapping in Langendorff-perfused hearts, we demonstrated that focal ectopies req
99 xt of well preserved contractile function in perfused hearts, we observed decreased glucose oxidation
109 eatment with BAPN increased outflow rates in perfused human and porcine anterior segments, whereas ge
110 r data has been developed and validated with perfused human DB-1 melanoma cells carrying the BRAF V60
112 utinin-I demonstrated an increased number of perfused human vessels in ECFC + MPC compared with ECFC.
113 ied habitats previously associated with well-perfused, hypoxic and/or necrotic tumor compartments.
118 eriments disrupting electrical conduction by perfusing intact adult and embryonic hearts with a gap j
119 lunteers, 50 mg purified (-)-epicatechin was perfused into an isolated jejunal segment together with
120 exogenously-derived mitochondria injected or perfused into ischemic hearts were rapidly internalised
122 ring new bone in vivo, removing it whole and perfusing it with culture medium in a microfluidic devic
123 sa NO production was similar in the isolated perfused juxtaglomerular apparatus of wild-type (WT) and
124 ond to tubuloglomerular feedback in isolated perfused juxtaglomerular apparatus preparations, althoug
127 oth the renal vascular perfusion pressure of perfused kidneys in vitro and renal blood flow in situ w
128 kers in the preservation solution of machine perfused kidneys may predict PNF, although evidence is l
133 risons with (1) published data for isolated, perfused livers with and without CCl4 intoxication and (
135 ltiphoton imaging of intravital and isolated perfused lung preparations incorporating fluorescent mol
136 d vascular permeability measured in isolated perfused lungs ex vivo increased at 2 wk after 15 Gy of
141 term (14-35 days) and phenotypic features of perfused microtumours compared with those in the static
142 muscle exhibited a steady ingrowth of blood-perfused microvasculature along with an increase in ampl
143 re we use an engineered organotypic model of perfused microvessels to show that activation of the tra
146 itin properties were analyzed in Langendorff-perfused mouse hearts after 20-minute ischemia/60-minute
150 tocol to measure glycogen levels in isolated perfused mouse livers using chemical exchange saturation
155 ys-162 by NO2-OA pretreatment in Langendorff-perfused murine hearts prevented the p38-MKK3 disulfide
157 dividing the volume of normal ventilated and perfused (%NVQ), unmatched and matched defects by the to
159 g, penetration of such molecules into poorly perfused or avascular tumor regions remains problematic.
170 tems for panoramic imaging using Langendorff-perfused pig hearts, a clinically-relevant model in basi
171 eriments were performed in isolated coronary perfused pig ventricular wall preparations stained with
175 rminals were significant targets for locally perfused pramipexole, ropinirole, and gabapentin, which
177 g an in vitro rat/mouse brain slice model of perfused/pressurized PAs; studies were supplemented with
181 n VF was induced electrically in Langendorff-perfused rabbit hearts (n=22) and terminated with a defi
190 TUDC exerts its choleretic properties in the perfused rat liver in an alpha5 beta1 integrin-mediated
193 canedioate (DODA), azelate, and glutarate in perfused rat livers, using a combination of metabolomics
195 cytosolic Ca(2+) concentrations in isolated perfused rat lungs, which could be blocked by respective
199 Furthermore, lactate entry into the better-perfused recipient cells has a favourable alkalinizing e
201 ration of ranolazine (5 mumol/L) in coronary-perfused right atrial and left ventricular preparations
202 Novel intramural optical mapping of coronary-perfused right atrial preparations revealed that adenosi
204 e found that warm branches had less sugar in perfused sap than cold branches due to increasing parenc
205 observed in young pigs; however, Langendorff-perfused SCN5A(E558X/+) hearts had an increased propensi
206 and contrast-to-noise ratios of ischemic and perfused segments on iodine material-density, monospectr
207 attenuation differences between ischemic and perfused segments on low-kiloelectron volt and iodine ma
208 attenuation difference between ischemic and perfused segments was significantly greater on dual-ener
209 ltage-calcium optical mapping of Langendorff-perfused SHR hearts revealed that H2 O2 -induced VT/VF a
210 itro (Franz cell chamber), ex vivo (isolated perfused skin models), and in vivo (vasoconstrictor assa
211 ntained an islet chamber with the ability to perfuse stimulants and an amino acid measurement system
217 ancement ratio between stenotic and normally perfused territories was determined for each stenosis.
218 s rhythmic contractions as a tube that helps perfuse the nascent vasculature, but the embryonic heart
219 The uterine arteries were cannulated to perfuse the organ with a buffer solution containing bloo
223 (+) concentration in patch pipette solutions perfusing the intracellular compartment was high and eli
224 five rats whose hindlimb muscles were freely perfused, the pressor and cardioaccelerator responses to
226 nt antagonist for NR2A-containing receptors, perfused through microdialysis probes, markedly reduced
228 eful in this pursuit, it must be able to (1) perfuse tissue and collect the perfusate for quantitativ
229 represents its partition coefficient in well-perfused tissue), and injection of (111)In-labeled white
237 ter arterial cannulation, the specimens were perfused using a combined detergent/polar solvent decell
238 ent networks in vitro and they generate well-perfused, vascular endothelial growth factor (VEGF)-inde
240 2.7 [2.6-2.9]; p < 0.003), the proportion of perfused vessels (from 79% [57-88%] to 92% [88-97%]; p <
241 0.4 n/mm, p < 0.001) and proportion of small perfused vessels (from 98% +/- 2% to 84% +/- 7%, p = 0.0
243 ial SDF results showed a lower proportion of perfused vessels and mean flow index during the febrile
246 ExECs were capable of forming functionally perfused vessels at the host/graft interface and increas
247 e microvascular flow index and proportion of perfused vessels in high Sequential Organ Failure Assess
249 ional capillary density, proportion of small perfused vessels, and PbO2 values but significantly high
250 ored at four forearm skin sites continuously perfused via intradermal microdialysis with: (1) lactate
252 al perfusion as it decreases the fraction of perfused villi in a synergistic manner, thereby increasi
257 1 mug/mL lipopolysaccharide for 6 hours and perfused with 100 mumol/L CORM-401 (or inactive compound
258 Cells attached to microcarrier beads were perfused with 26 mm [1,6-(13)C2]glucose under normoxic c
261 chemia, 3.5 hours of cold ischemia, and then perfused with a humanized anti-CD47 monoclonal antibody
267 le perfused rat mesenteric microvessels were perfused with fluorescent endothelial cell membrane and
269 hese thick vascularized tissues are actively perfused with growth factors to differentiate hMSCs towa
270 Five discarded high-risk human livers were perfused with HBOC-based perfusion fluid and matched to
272 vel metabolite that accumulates in rat liver perfused with HNE or 4-hydroxynonanoic acid (HNA), ident
273 er two intradermal microdialysis probes, one perfused with ISO saline and the other with HYPER saline
274 Protocol 1 (n = 8), microdialysis sites were perfused with lactated Ringer solution (Control), 40 pm,
275 0 nm ET-1; in Protocol 2 (n = 11) sites were perfused with lactated Ringer solution (Control), 400 nm
276 e inserted into the right frontal cortex and perfused with mock CSF with 3% Dextran 500 at a flow rat
281 l experiments, kidneys were normothermically perfused with oxygenated blood for 1 hour after cold sto
282 om an ischemia/reperfusion Langendorff model perfused with oxygenated blood from an arrested animal b
283 s presenting up to 90 min warm ischemia were perfused with oxygenation at 4 degrees C using our magne
286 used livers extracted more oxygen than those perfused with RBCs (O2 extraction ratio 13.75 vs 9.43 %
288 ed vasodilatation, microdialysis fibres were perfused with Ringer solution (control), a ATP-sensitive
289 gnalling pathways, microdialysis fibres were perfused with Ringer solution (control), a non-specific
291 Nav1.5, Cav1.2, or Kv4.2 were coexpressed or perfused with SEMA3A in HEK293 cells, and electrophysiol
292 egion, by contrast, is less hypoxic as it is perfused with small arteries that are often positive for
295 D and LVDP were significantly higher in LWHs perfused with TOLB (199 +/- 16 ms; 92 +/- 5.3 mmHg) than
299 rectly into the KF of the in situ arterially perfused working heart-brainstem preparation of rat resu
300 ately, exogenous A2AR antagonism in elastase-perfused WT mice also resulted in larger aneurysms (P<0.
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