ライフサイエンスコーパス: periarticular

1 In this study, we demonstrate that periarticular administration of exosomes purified from e

2 Similarly, local, periarticular administration of lactoferrin into S aureu

3 These individuals lacking ENT1 exhibit periarticular and ectopic mineralization, which confirms

4 Interestingly, ASCs protected periarticular and systemic bone loss in CIA mice by main

5 aracterized by joint inflammation as well as periarticular and systemic bone loss.

6 joints were examined for marrow, articular, periarticular, and soft-tissue findings.

7 Because progressive destruction of the periarticular bone contributes significantly to joint dy

8 e osteoclast activity is responsible for the periarticular bone destruction that characteristically o

9 Periarticular bone erosion and bone edema were scored ac

10 ith devastating joint tissue destruction and periarticular bone erosion.

11 Finally, osteoclastogenesis and periarticular bone erosions are markedly increased in SH

12 rder that involves cartilage degradation and periarticular bone response.

13 d schedule-dependent preservation of BMD and periarticular bone while essentially eliminating intrale

14 oarthritis (OA), a disorder of cartilage and periarticular bone, is a public health problem without e

15 might have adverse effects on cartilage and periarticular bone.

16 with erosion of the articular cartilage and periarticular bone.

17 NTPPPH PC-1 caused infantile wrist and ankle periarticular calcification and vascular calcification.

18 Elbow and MCP joint periarticular calcifications were observed in 35 and 5 p

19 the elongation of columns and stimulation of periarticular chondrocyte differentiation in these model

20 n of periarticular to columnar chondrocytes (periarticular chondrocyte differentiation) and thereby r

21 action, PTHrP upregulation, acceleration of periarticular chondrocyte differentiation, and elongatio

22 , elongation of columns, and acceleration of periarticular chondrocyte differentiation.

23 t Ihh positively controls differentiation of periarticular chondrocytes independently of PTHrP.

24 In the developing growth plate, periarticular chondrocytes proliferate, differentiate in

25 was also noted in this mouse, while most of periarticular chondrocytes retained PPR signaling.

26 These results demonstrate that Ihh acts on periarticular chondrocytes to stimulate their differenti

27 of columnar chondrocytes, Ihh action in the periarticular chondrocytes was upregulated because of ec

28 es, chondrocytes near the articular surface (periarticular chondrocytes) proliferate, differentiate i

29 tflow buffering facilitates fluid escape and periarticular edema.

30 Periarticular erosion formation may not necessarily depe

31 degree of flexor tenosynovitis (P = 0.532), periarticular erosions (P = 0.579), or degree of bone ed

32 reased osteoclastic bone resorption leads to periarticular erosions and systemic osteoporosis in RA p

33 acroscopic evidence of CIA first appeared as periarticular erythema and edema in the hind paws by day

34 rtrophic differentiation by signaling to the periarticular growth plate and also determines the site

35 -related peptide (PTHrP), synthesized in the periarticular growth plate, regulates the site at which

36 but is less important in the pathogenesis of periarticular inflammation in this disease.

37 tivity after both peripheral soft tissue and periarticular inflammation was abolished.

38 between days 10 and 18, was characterized by periarticular inflammation with marked synovitis, synovi

39 aw swelling and deformity, less synovial and periarticular inflammation, and markedly decreased bone

40 Alternatively, in states of severe periarticular inflammation, TNF-alpha may fully exert it

41 raphy and MRI typically show a predominantly periarticular inflammatory process.

42 Periarticular injection of 125I-lactoferrin confirmed th

43 profoundly inhibited joint inflammation and periarticular joint destruction in a dose-dependent mann

44 knee pain and those without knee pain, other periarticular lesions (including bursitis and iliotibial

45 However, other periarticular lesions were present in 14.9% of patients

46 infrapatellar, deep infrapatellar) or "other periarticular lesions" (semimembranosus-tibial collatera

47 MRIs were read for the presence of periarticular lesions, which were categorized (according

48 lux, joint levels of prostaglandin E(2), and periarticular osteoclast formation were inhibited by tur

49 rom ovariectomy-induced osteoporosis and the periarticular osteolysis attending inflammatory arthriti

50 therefore, IL-1 plays a role in TNF-induced periarticular osteolysis.

51 lar joint tissue associated with progressive periarticular osteolytic lesions.

52 are frequently unremarkable, but may reveal periarticular osteopenia 3-6 weeks after the onset of cl

53 Mice in both age groups developed periarticular osteophytes at the tibial plateau in respo

54 roid hormone-related protein (PTHrP), in the periarticular perichondrium.

55 se models, upregulation of Ihh action in the periarticular region was also observed.

56 In the marrow, periarticular signal intensity abnormality was common in

57 localized to one painful, tender and swollen periarticular site 86% of the time.

58 identifying uric acid deposits in joints and periarticular soft tissues in patients suspected of havi

59 The surrounding periarticular soft tissues, bone structures, joint space

60 In the periarticular soft tissues, edema, enhancement, and ulce

61 ealed only scattered rare lymphocytes in the periarticular soft tissues, without joint destruction.

62 aterally to rapidly stress the knee's medial periarticular structures and create a potentially destab

63 The MR appearances of all articular and periarticular structures were analyzed and compared with

64 The MR appearances of all intraarticular and periarticular structures were analyzed and correlated wi

65 yloid infiltration into soft tissue, joints, periarticular structures, and bones can bring patients w

66 roved the visualization of all articular and periarticular structures.

67 ods of time when injected locally within the periarticular tissue surrounding the ankle joints of mic

68 ity over TIMP action in the invading pannus, periarticular tissue, or SF.

69 onosodium urate (MSU) crystals in joints and periarticular tissues.

70 inflammation, both in synovium and in other periarticular tissues.

71 show that Ihh stimulates differentiation of periarticular to columnar chondrocytes (periarticular ch

72 Acceleration of periarticular to columnar differentiation was also noted

73 e terminal step but also at an earlier step: periarticular to columnar differentiation.