1 nsion was recorded during continuous dynamic
perifusion.
2 RESEARCH DESIGN AND
Perifusion analyses of isolated Munc18c- (-/+) or Munc18
3 Islet
perifusion and calcium imaging studies showed abnormal r
4 Islet
perifusion and calcium-imaging studies showed abnormal r
5 nsulin secretion ability by in vitro glucose
perifusion and explore the expression of insulin pathway
6 Perifusion assays using pancreatic islets from transgeni
7 Further,
perifusion assays with human islets isolated from a dono
8 In ex vivo
perifusion assays, Smad3-deficient islets exhibit improv
9 e insulin secretion profile in dynamic islet
perifusion assays.
10 ucose-stimulated insulin release response in
perifusion assays.
11 Under
perifusion conditions, high glucose concentrations induc
12 n from islets and beta cells under static or
perifusion conditions, whereas an inactive structural an
13 glucose-stimulated insulin release in islet
perifusion experiments and have significantly reduced pa
14 Perifusion experiments indicated that cPLA(2) underexpre
15 Perifusion experiments with human islets indicated that
16 In
perifusion experiments with isolated islets in the absen
17 In
perifusion experiments, acute insulin responses (AIRs) i
18 In
perifusion experiments, elevations in extracellular Ca2+
19 e studied using [Ca(2+)] imaging, static and
perifusion insulin secretion assays, and gap junction pe
20 During islet
perifusions,
KIC and 2 mM glutamine caused robust dose-d
21 During local CTX + APA
perifusion,
L-NNA + INDO abolished SCVD while conducted
22 Low-Ca2+ or Ca(2+)-free
perifusion medium induced oscillatory bursting activity
23 d currents (IPSCs) were usually blocked with
perifusion of 10-50 microM bicuculline methiodide (BMI).
24 actional [3H]ACh release was recorded during
perifusion of acutely dissociated, [3H]choline-labeled,
25 However, simultaneous
perifusion of explants with ATP (100 micrometer) and PE
26 Perifusion of fatty acids restored both responses.
27 In the second experiment,
perifusion of hypothalamic slices with 10(-8) or 10(-7)
28 Perifusion of neurexin-1alpha KO mouse islets revealed a
29 Perifusion of slices with 7.5-10 mM TEA, a K+ channel bl
30 Perifusion of slices with media containing 1-2 microM TT
31 failed to induce an IDAP-like current during
perifusion of slices with media containing high [K+]o or
32 Perifusion of Syn-1A-betaKO islets showed impaired first
33 Surprisingly, insulin secretion in
perifusion or static incubation experiments in response
34 measured every 20 min during a 3-h baseline
perifusion period and after depolarization with 56 mM KC
35 functional capacity of islets as assessed by
perifusion (
r=0.60; P=0.022).
36 s was confirmed in vitro by pancreatic islet
perifusion showing an amplified biphasic glucose-stimula
37 Isolated islet
perifusion studies demonstrated that exendin-(9-39) bloc
38 Islet
perifusion studies failed to demonstrate abnormalities i
39 Perifusion studies indicate that the inhibition of [3H]p
40 e to glucose plus isobutyl-methylxanthine in
perifusion studies that is clearly larger in magnitude t
41 Perifusion studies using pharmacologic inhibitors (genis
42 ycemic clamps, as well as isolated islet and
perifusion studies.
43 A
perifusion study revealed that leptin (50 ng/ml) affecte
44 elease obtained from the same islet lot in a
perifusion system (n=12).
45 Using a
perifusion system to follow secretion over time revealed
46 rent GnRH pulse frequencies using a parallel
perifusion system.
47 ch was cut into fine slices and subjected to
perifusion to monitor glucagon release.
48 his response was not observed if the insulin
perifusion was not switched off when the islets were dep
49 Similarly, in a third experiment,
perifusion with 10(-7) M insulin caused a significant de
50 Perifusion with 16.7 mmol/l glucose plus 0.1 mmol/l IBMX
51 Perifusion with ATP before mechanical stimulation suppre
52 During local
perifusion with KCa antagonists, iberiotoxin (5 microm)
53 kade of Ca2+ release from internal stores by
perifusion with ryanodine or dantrolene, or direct diffu
54 Depletion of internal Ca2+ stores by
perifusion with thapsigargin or cyclopiazonic acid also
55 n freshly isolated mouse acinar cells during
perifusion with the bile acid taurolithocholic acid 3-su
56 ed pituitary cells and from cells undergoing
perifusion with the peptides.