ライフサイエンスコーパス: perikaryal

1 the result of impaired axonal transport and perikaryal accumulation in the large neuron sub-populati

2 rt into and along axons, resulting in severe perikaryal accumulation of neurofilaments and proximal a

3 aluminum neurotoxicity is accompanied by the perikaryal accumulation of tangles of phosphorylated neu

4 erosis (ALS), motor neurons contain abnormal perikaryal accumulations of phosphorylated neurofilament

5 d neurons that displayed increased p-NF-H in perikaryal accumulations that colocalized with Pin1 and

6 n proximity ligation assay labels very early perikaryal aggregates in morphologically intact neurons

7 Multiple perikaryal aggregates were present in almost all cortica

8 uminum impairs axonal transport and promotes perikaryal aggregation.

9 n induces deregulated Cdk5 hyperactivity and perikaryal aggregations of hyperphosphorylated Tau and n

10 logical conditions can involve both neuronal perikaryal and axonal damage, yet considerably less is k

11 es immunoreactive (IR) for PARV and NPY were perikaryal and dendritic and found within the infragranu

12 Perikaryal and dendritic labeling was mostly intracellul

13 s, specifically accumulation and bundling of perikaryal and dendritic neurofilaments.

14 sions in NADPH-diaphorase neurons, with less perikaryal and neuropil aggregation.

15 In the pons and medulla, both perikaryal and neuropil labeling were observed.

16 consistent with actions on GnRH-1 neurons at perikaryal and/or terminal levels.

17 tic abnormalities persisted and motor neuron perikaryal atrophy had appeared.

18 olabeling was found within the thin shell of perikaryal cytoplasm that contained the usual organelles

19 tributions: QKI-6 and QKI-7 are localized to perikaryal cytoplasm, whereas QKI-5 invariably is restri

20 se-dependent increase in myelin and neuronal perikaryal damage.

21 The perikaryal diameters and lengths of the immunoreactive d

22 The mean perikaryal diameters and median summed lengths of dendri

23 In contrast, nuclear or perikaryal huntingtin aggregates were present in less th

24 ystin LR (mLR), or fostriecin (Fos) leads to perikaryal hyperphosphorylation of NF.

25 cause of the effects of NGF on memory is not perikaryal hypertrophy per se but rather an increased de

26 nsity of terminals, which always accompanies perikaryal hypertrophy.

27 y using affinity-purified antisera, we found perikaryal labeling was diffuse and/or punctate; immunor

28 Light perikaryal labeling was found in other areas of the brai

29 disease, BC200 RNA often assumed a clustered perikaryal localization, indicating that dendritic loss

30 nin-a2 interaction resulted in altered MAP1B perikaryal localization, leading to MT deacetylation and

31 ture of the glial and axonal coverage of the perikaryal membrane and the somatic spines in the MePD o

32 up) showed that the rat MePD has most of the perikaryal membrane covered by glial processes and a rel

33 The percentage of GnRH perikaryal membrane occupied by synaptic density in the

34 Differences in the percentage of GnRH perikaryal membrane occupied by synaptic density were no

35 ty of somatic spines along the length of the perikaryal membrane was higher in the late proestrus tha

36 dephosphorylation by aluminum would promote perikaryal NF phosphorylation and foster precocious phos

37 Thus, while neither perikaryal nor axonal neurofilaments are essential for S

38 size nor morphological traits of NPY-labeled perikaryal or dendritic profiles from lesioned compared

39 Steady-state levels of perikaryal phospho-NF immunoreactivity are reduced and t

40 transport into axonal neurites and increased perikaryal phospho-NF immunoreactivity.

41 The H(2)O(2) and heat shock induced perikaryal phospho-NF-H accumulations, and neuronal apop

42 ibition of Pin1 inhibits OA-induced aberrant perikaryal phosphorylation of NF.

43 presynaptic component, and layer 6 displayed perikaryal postsynaptic staining, suggesting that cortic

44 These active kinases distributed mainly in perikaryal regions of neurons.

45 en these two corticostriatal neuron types in perikaryal size and laminar location in the cortex, and

46 their laminar location in the cortex, their perikaryal size, and the morphology of their intrastriat

47 eurons and a 28% increase in dopamine neuron perikaryal size.

48 Very few pyramidal neurons exhibited perikaryal staining.