ライフサイエンスコーパス: periodontitis

1 elopment of a new host modulation therapy in periodontitis.

2 lls on periodontal bone loss in experimental periodontitis.

3 pants had periodontitis, and 9.1% had severe periodontitis.

4 n treatment of IBDs in patients with chronic periodontitis.

5 linical AL, and higher odds of having severe periodontitis.

6 hree-fold increase in the odds of developing periodontitis.

7 riodontal pockets and contributes to chronic periodontitis.

8 nt of intrabony defects (IBDs) in aggressive periodontitis.

9 ease burden and significant association with periodontitis.

10 ater extent in patients without a history of periodontitis.

11 nt was only observed in patients with severe periodontitis.

12 e predictive contribution of ETS exposure to periodontitis.

13 umbers are elevated in patients with chronic periodontitis.

14 e influence of ETS exposure on occurrence of periodontitis.

15 tion of the periodontium that is lost due to periodontitis.

16 0.05), highlighting their potential role in periodontitis.

17 examinations demonstrated the development of periodontitis.

18 ts were divided into two groups: control and periodontitis.

19 tes toward understanding of the pathology of periodontitis.

20 r 71 polymorphisms in 29 candidate genes for periodontitis.

21 ic inquiry in the management of inflammatory periodontitis.

22 y, dentoalveolar bone); and 3) management of periodontitis.

23 ate and adaptive immunity in the etiology of periodontitis.

24 le of CBCT in the management of inflammatory periodontitis.

25 as gingivalis, the main etiological agent of periodontitis.

26 en with moderate, and four with mild chronic periodontitis.

27 s pH changes, may be beneficial for treating periodontitis.

28 ment of patients with generalized aggressive periodontitis.

29 d at the messenger RNA (mRNA) level in human periodontitis.

30 ssified as healthy/mild, moderate, or severe periodontitis.

31 , and negatively with IL-34 in patients with periodontitis.

32 ly to IL-34, in patients with gingivitis and periodontitis.

33 ntioxidant enzymes in rats with experimental periodontitis.

34 stratified by sex for each classification of periodontitis.

35 iologic testing is examined in patients with periodontitis.

36 other risk factors may increase the risk of periodontitis.

37 3) alveolar bone loss (ABL) in experimental periodontitis.

38 ifications play a role in the development of periodontitis.

39 ls), the most severe and early onset form of periodontitis.

40 et-induced overweight/obesity on the risk of periodontitis.

41 ne model of A. actinomycetemcomitans-induced periodontitis.

42 onded to a CRR of 5:4, correlating to severe periodontitis.

43 resulting in the common inflammatory disease periodontitis.

44 samples to identify genetic risk variants of periodontitis.

45 using an established model of polymicrobial periodontitis.

46 ukin (IL)-12 correlates with the severity of periodontitis.

47 ipidemia measures no factors were related to periodontitis.

48 d to a CRR of 1:1, relating to mild-moderate periodontitis.

49 creases the risk of an individual developing periodontitis.

50 plays a central mechanism in pathogenesis of periodontitis.

51 ctive approaches for preventing and treating periodontitis.

52 ar bone loss (ABL) in rats with experimental periodontitis.

53 thers showed t2DM development, regardless of periodontitis.

54 tal cholesterol, and C-reactive protein with periodontitis.

55 could be therapeutic tools for treatment of periodontitis.

56 riodontal bacterial profile in patients with periodontitis.

57 upled receptor X2 (MRGPRX2), is increased in periodontitis.

58 t treatment outcome of patients with chronic periodontitis.

59 determined in 48 patients (29 patients with periodontitis, 12 with gingivitis, and seven healthy pat

60 overweight) and 22% (obesity) higher risk of periodontitis; 12% (overweight) and 27% (obesity) higher

61 risk under no intervention was 33.3% for any periodontitis, 14.3%, for moderate/severe periodontitis,

62 Key variables assessed included: 1) periodontitis; 2) body mass index; 3) waist circumferenc

63 27% (obesity) higher risk of moderate/severe periodontitis; 21% (overweight) and 57% (obesity) higher

64 To create experimental periodontitis, 4/0 silk ligatures were inserted submargi

65 -deficient (TLR9(-/-)) mice are resistant to periodontitis, a disease characterized by a dysbiotic mi

66 sponses play an important role in aggressive periodontitis (AgP).

67 and Dutch case-control sample of aggressive periodontitis (AgP, 896 cases, 7,104 controls), a rare b

68 m a German case-control sample of aggressive periodontitis (AgP; 651 cases, 4,001 controls), the most

69 .05) relative to the sites with experimental periodontitis alone.

70 rtunity to clinically validate self-reported periodontitis among a sample of participants.

71 This study reveals a high burden of periodontitis among adults living in circumpolar communi

72 on data were used to determine prevalence of periodontitis among United States non-smoking adults and

73 of this study are to estimate prevalence of periodontitis among United States non-smoking adults exp

74 Diabetes is a risk factor for periodontitis, an inflammatory bone disorder and the gre

75 from 25 individuals with generalized chronic periodontitis and 25 periodontally healthy individuals u

76 in the validation sample was 24% for severe periodontitis and 61% for moderate disease.

77 Forty-five patients with chronic periodontitis and a total of 164 screw-typed implants wi

78 adhesion deficiency type 1 (LAD1) had severe periodontitis and an intractable, deep, nonhealing sacra

79 tio (CRR) of extracted teeth to classify the periodontitis and assign a periodontal/prosthetic progno

80 orrelations that were being observed between periodontitis and cardiovascular disease, rheumatoid art

81 ne whether the genetic background of initial periodontitis and caries could be detected using an acti

82 investigate the association between induced periodontitis and damage caused through its systemic eff

83 h in GCF and serum, increased from health to periodontitis and decreased with non-surgical periodonta

84 study is to evaluate the association between periodontitis and ED by means of periodontal clinical pa

85 case definitions and of male sex with severe periodontitis and EWP-specific definitions.

86 review of the potential association between periodontitis and gestational diabetes mellitus (GDM) in

87 Results demonstrated higher prevalence of periodontitis and higher levels of GCF IL-1beta and seru

88 howed sociodemographic disparities regarding periodontitis and highlights the importance of further i

89 serum CRP modified the relationship between periodontitis and NAFLD ( Pinteraction = 0.01).

90 ion models estimated the association between periodontitis and NAFLD within strata of serum CRP and s

91 matory burden modify the association between periodontitis and NAFLD.

92 An association between periodontitis and nonalcoholic fatty liver disease (NAFL

93 A possible association between periodontitis and obstructive sleep apnea (OSA) has been

94 ver alternative therapeutic targets to treat periodontitis and other chronic inflammatory diseases.

95 icant changes were still observed for severe periodontitis and progression of AL with increases of 0.

96 parameters in the interrelationship between periodontitis and RA remains unclear.

97 Sixteen patients with periodontitis and six periodontally healthy volunteers (

98 Periodontitis and smoking may result in thickening of th

99 e actual relationship between STC levels and periodontitis and to establish causality and directional

100 (LPS); and 4) rats submitted to experimental periodontitis and treated with HU-308 (LPS+HU).

101 ny periodontitis, 14.3%, for moderate/severe periodontitis, and 14.7%, for BOP and CAL.

102 case definitions, 49.5% of participants had periodontitis, and 9.1% had severe periodontitis.

103 microbiologic profiles of peri-implantitis, periodontitis, and healthy implants based on studies tha

104 Hyposalivation contributes to dental caries, periodontitis, and microbial infections.

105 loss is the ultimate negative consequence of periodontitis, and reports of the extent to which differ

106 oduction of antioxidants in individuals with periodontitis, and significantly decreased glutamate met

107 are the main trigger for the development of periodontitis, and some species are known to modulate ne

108 e risk of any periodontitis, moderate/severe periodontitis, and the combination of bleeding on probin

109 and S. sputigena, seem to be associated with periodontitis, and their role in periodontal pathogenesi

110 To evaluate the effects of DC-STAMP in periodontitis, anti-DC-STAMP-monoclonal antibody (mAb) w

111 randomized clinical trial, 80 patients with periodontitis are distributed randomly into two groups.

112 ip of expression of Wnt5a and sFRP5 in human periodontitis (as compared to health) and to determine t

113 ism (SNP) context of a previously identified periodontitis-associated locus is investigated, and its

114 n orthologous were interrogated for putative periodontitis-associated variants using existing GWAS da

115 disease phenotypes and were associated with periodontitis at a genome-wide significance level in the

116 Periodontitis at age 31 years according to six classific

117 the study was to estimate the prevalence of periodontitis at state and local levels across the Unite

118 needs is evaluated in patients with chronic periodontitis before and after completion of non-surgica

119 n situ growth activities of oral bacteria in periodontitis before and after non-surgical periodontal

120 Prevalence of severe periodontitis (biofilm-gingival interface P3 classificat

121 sibility of using the Wnt5a/sFRP5 ratio as a periodontitis biomarker.

122 Mast cells play an important role in periodontitis, but the mechanisms of their activation an

123 ant associations of age and smoking with all periodontitis case definitions and of male sex with seve

124 uate differences in outcome by applying five periodontitis case definitions for cross-sectional assoc

125 Number of cases captured by the five periodontitis case definitions ranged from 337 (9.2%) to

126 tle difference in odds ratio across the five periodontitis case definitions; however, the level of si

127 A total of 224 participants were defined as periodontitis cases by all five criteria.

128 Periodontitis classifications with lower thresholds yiel

129 Due to the limited sample size of available periodontitis cohorts and the underlying trait heterogen

130 -1/IL-34 ratio was observed in patients with periodontitis compared with healthy patients.

131 45 patients with chronic periodontitis comprising 164 screw-typed implants with p

132 flammation and disease symptoms in models of periodontitis corresponding to recruitment of endogenous

133 forms of the more moderate phenotype chronic periodontitis (CP) (993 cases, 1,419 controls).

134 evels in the saliva of patients with chronic periodontitis (CP) and acute coronary syndrome (ACS) and

135 clinical parameters of patients with chronic periodontitis (CP) and diabetes mellitus (DM).

136 individuals with aggressive (AgP) or chronic periodontitis (CP) and healthy controls (HC), as well as

137 zed aggressive periodontitis (GAgP), chronic periodontitis (CP) and in patients with no history of pe

138 Chronic periodontitis (CP) has a genetic component, particularly

139 e-wide association studies (GWAS) of chronic periodontitis (CP) have been unsuccessful in discovering

140 bony defects (IBDs) in patients with chronic periodontitis (CP).

141 = 20), individuals with generalized chronic periodontitis (CP).

142 the treatment of moderate and severe chronic periodontitis (CP).

143 polycystic ovary syndrome (PCOS) and chronic periodontitis (CP).

144 ect (IBD) treatment in patients with chronic periodontitis (CP).

145 o two groups: 1) 24 individuals with chronic periodontitis (CP); and 2) 23 individuals without CP.

146 ree groups: 1) healthy (control); 2) chronic periodontitis (CP); and 3) myocardial infarction (MI).

147 vel (two lowest groups) was related to three periodontitis criteria.

148 stemic, and socioeconomic data on estimating periodontitis development in a population-based prospect

149 Prediction of periodontitis development is challenging.

150 socioeconomic characteristics on accuracy of periodontitis development prediction.

151 Periodontitis develops through an inflammatory process c

152 matory mediators previously described in the periodontitis disease.

153 histamine and ECP in the progression of the periodontitis disease.

154 Patients with periodontitis displayed higher CSF-1 and MMP-8 levels in

155 of the genus Bifidobacterium on experimental periodontitis (EP) in rats.

156 ratrol (RESV) on progression of experimental periodontitis (EP) in the presence of cigarette smoke in

157 action of healthy or teeth with experimental periodontitis (EP) in Wistar-Han rats treated with zoled

158 divided into control, experimentally induced periodontitis (EP), DM, EP-DM, EP and melatonin treatmen

159 Patients with periodontitis, especially those who smoke, suffer from a

160 eriodontitis was defined according to severe periodontitis, European Workshop of Periodontology (EWP)

161 al prognosis and determining the severity of periodontitis for premolars with alveolar bone loss base

162 There was a 28% increase in the odds of periodontitis for those with any ETS exposure compared w

163 nts with a history of generalized aggressive periodontitis (GAgP), chronic periodontitis (CP) and in

164 In periodontitis, genetics and smoking play important roles

165 osed DM and prediabetes were observed in the periodontitis group (32.7%) than in the control group (1

166 alis levels were significantly higher in the periodontitis group (P <0.05), and Td levels were signif

167 a marked reduction in NG2+ pericytes in the periodontitis group compared with the control group.

168 The periodontitis group had significantly lower GSH and high

169 levels were similar in peri-implantitis and periodontitis groups (P >0.05).

170 of NLRP3, ASC, and IL-1beta were detected in periodontitis groups in comparison to the periodontally

171 itis (CP) and in patients with no history of periodontitis (H), using microarray and quantitative rev

172 Periodontitis has been associated with a greater risk fo

173 meter of early ACD, and its association with periodontitis has rarely been investigated to date.

174 monas gingivalis, a major etiologic agent of periodontitis, has been reported to induce the expansion

175 Teeth with periodontitis, healthy implants, or implants with peri-i

176 treated with dental implants with different periodontitis histories and the possible influence of th

177 ion with compliance level; however, positive periodontitis history and more years in function were si

178 Patients with periodontitis history demonstrated greater compliance th

179 ted greater compliance than patients without periodontitis history during the two longer follow-up ti

180 lly comply with scheduled SPT, regardless of periodontitis history.

181 in E1 (RvE1), effectively treat inflammatory periodontitis in animal models.

182 phisms of MMP3 and VDR are linked to initial periodontitis in Finnish adolescents, and the aMMP-8 cha

183 l inflammation and bone loss in experimental periodontitis in mice.

184 and root planing (SRP) for treating chronic periodontitis in patients with type 2 diabetes.

185 udies have identified a greater incidence of periodontitis in patients with type 2 diabetes.

186 and liver disease caused by ligature-induced periodontitis in rats.

187 <0.05) were recorded by diagnosis of chronic periodontitis in the a* coordinate when comparing treatm

188 ribe the prevalence, severity, and extent of periodontitis in the adult population of circumpolar com

189 mful) association between FRC use and severe periodontitis in the entire sample (odds ratio [OR]: 1.7

190 Prevalence of periodontitis in the OSA group (96.4%) was significantly

191 The rate of periodontitis in the US population has been estimated to

192 d bone loss in ligature-induced experimental periodontitis in vivo Purified spleen B cells from C57BL

193 ication, predictive value for development of periodontitis in young adults might be increased by comb

194 chairside test can eventually detect initial periodontitis in young patients with predisposing geneti

195 ural teeth [19 healthy, 12 gingivitis, eight periodontitis] in 15 systemically healthy patients were

196 ith anti-inflammatory properties, to inhibit periodontitis induction via a thermogelling and pH-respo

197 sFRP5 in mice subjected to ligature-induced periodontitis inhibited inflammation and bone loss, corr

198 Periodontitis is a chronic inflammatory and bone-destruc

199 Periodontitis is a chronic inflammatory disease induced

200 Periodontitis is a chronic inflammatory disease that occ

201 Periodontitis is a common dysbiotic inflammatory disease

202 Periodontitis is a global health problem and the 6(th) m

203 Periodontitis is caused by subgingival colonizing bacter

204 Periodontitis is considered to be a risk factor for pret

205 Chronic periodontitis is controlled without antibiotics by scali

206 Periodontitis is one of the most common inflammatory dis

207 Knowledge of new strategies to treat periodontitis is particularly relevant in patients prese

208 he aim of this study is to determine whether periodontitis is related to the amyloid beta (Abeta) loa

209 mycetemcomitans infection and progression to periodontitis is still ill-defined.

210 n is upregulated in the gingival tissue with periodontitis, its pathophysiological roles in periodont

211 oxic JP2 genotype, with localized aggressive periodontitis (LAgP).

212 suggests that DHA + aspirin therapy improves periodontitis largely by modulating host inflammatory re

213 minant disorder characterized by early-onset periodontitis leading to premature loss of teeth, joint

214 sham rats; 3) rats submitted to experimental periodontitis (LPS); and 4) rats submitted to experiment

215 According to these data, periodontitis may be a modulating variable of the associ

216 role of bridging species in pathogenesis of periodontitis may be greater than previously suspected i

217 Associations of risk factors/indicators with periodontitis may depend on the included case criterion.

218 The presence of periodontitis may modify the association between Abeta a

219 1 was also observed in a murine experimental periodontitis model induced by P. gingivalis-soaked liga

220 for race or sex, whereas prevalence of total periodontitis (moderate and severe) among women of simil

221 The risk of any periodontitis, moderate/severe periodontitis, and the co

222 sease" and two inquired about "self-assessed periodontitis." Multiple logistic regression models were

223 tested in a mouse model of ligature-induced periodontitis ( n = 6-7/group) where Pasteurella pneumot

224 vitis (n = 21) and some of the patients with periodontitis (n = 11) were subjected to non-surgical pe

225 viduals (n = 2) and individuals with chronic periodontitis (n = 2) was done via immunohistochemistry.

226 In cases with severe periodontitis (n = 24), amoxicillin and metronidazole (A

227 In cases with severe periodontitis (N = 24), amoxicillin and metronidazole (A

228 status was examined in patients with severe periodontitis (n = 49) and healthy controls (n = 39), an

229 tory findings in individuals with or without periodontitis (N = 88).

230 Damage caused by periodontitis not only affects periodontal tissues, but

231 might have an impact on accuracy to predict periodontitis occurrence.

232 Sixty patients with chronic periodontitis on 6-month PMT intervals to be followed fo

233 Current evidence indicates the effects of periodontitis on diabetes as well as mortality, for whic

234 1:1 was inadequate to assess the severity of periodontitis on the basis of the 2D RL and 3D RSA measu

235 were not frequently identified in teeth with periodontitis or healthy implants.

236 spase-3, 6.8-fold; Xiap: 2.5-fold in chronic periodontitis) (P < 0.05), highlighting their potential

237 y is to investigate whether neutrophils from periodontitis patients are able to produce Eosinophil Ca

238 We found that neutrophils from periodontitis patients express higher levels of histidin

239 fluorescence microscopy in neutrophils from periodontitis patients in response to LPS.

240 human gingival tissue specimens from chronic periodontitis patients, further confirming the biologica

241 eatment, and in subgingival dental plaque of periodontitis patients, indicating that eDNA is a common

242 tients with the chronic inflammatory disease periodontitis (PD).

243 nnabis (FRC) (marijuana and hashish) use and periodontitis prevalence among adults in the United Stat

244 Periodontitis prevalence and severity increased with age

245 The aim of this study is to compare periodontitis prevalence between controls and patients w

246 Periodontitis prevalence in the validation sample was 24

247 Severe periodontitis prevalence was higher in the OSA group tha

248 Periodontitis prevalence was positively associated with

249 grating multiple datasets to assess risk for periodontitis progression and tooth loss in dental patie

250 d association between obesity and subsequent periodontitis progression in a longitudinal database.

251 fect of baseline central adiposity on future periodontitis progression is conditional on proinflammat

252 Periodontitis progression was associated with increase i

253 Severe periodontitis ranged from 7.27% in New Hampshire to 10.2

254 Eighty patients with chronic or aggressive periodontitis received periodontal treatment supplemente

255 Patients with periodontitis received SRP and surgery, and HVs received

256 riodontitis, its pathophysiological roles in periodontitis remain unclear.

257 yromonas gingivalis, a keystone pathogen for periodontitis, revealed reduced neutrophils in TLR9(-/-)

258 ential of salivary MRP-8/14 was detected for periodontitis (ROC = 0.86).

259 ons of IL-1 genetic patterns associated with periodontitis severity and progression.

260 Biofilm CF is associated with periodontitis severity pretherapy and extent of therapeu

261 leukin (IL)-1 gene variants, known to affect periodontitis severity, influence the previously reporte

262 se of statins on adult patients with chronic periodontitis shows a positive effect on their periodont

263 In 50 patients with periodontitis, subgingival plaque was sampled from the d

264 ant in patients presenting augmented risk to periodontitis, such as smokers.

265 nse to the possibility of under-reporting of periodontitis, the Centers for Disease Control updated p

266 In patients with periodontitis, the visfatin levels in the GCF (mean: 84.

267 ts in patients with and without a history of periodontitis through a deep-sequencing approach.

268 les harvested from human healthy and chronic periodontitis tissues (Apaf-1, 19.2-fold; caspase-9, 14.

269 peri-implantitis versus healthy implants or periodontitis using conventional microbiologic technique

270 re but highly severe and early-onset form of periodontitis, validated the associations in a German sa

271 Periodontitis was a significant interaction variable, gi

272 As in humans, mouse periodontitis was associated with high expression of Wnt

273 estionnaire items with respect to predicting periodontitis was better for severe compared with modera

274 Periodontitis was defined according to severe periodonti

275 Periodontitis was defined as the percentage of sites (0%

276 Periodontitis was detected in 77.1% of females with oste

277 me was statistically significant when severe periodontitis was diagnosed at baseline (2.32%, 95% conf

278 Prevalence of periodontitis was higher among men and varied between ur

279 as subgingivally delivered when experimental periodontitis was induced in vivo, and therapeutic effec

280 Moderate to severe periodontitis was noted in 98% of patients with RA and 8

281 Periodontitis was positively associated with ED, express

282 Periodontitis was positively associated with higher prev

283 Treponema denticola, a keystone pathogen of periodontitis was reported.

284 Prevalence of severe periodontitis was similar to other age-comparable popula

285 Murine experimental periodontitis was used to assess disease severity.

286 Primary outcome (periodontitis) was defined using the Centers for Disease

287 In a ligature-induced model of periodontitis, we demonstrate that TLR9(-/-) mice exhibi

288 gin to understand the role of P. stomatis in periodontitis, we studied its interactions with human ne

289 mplantitis compared with healthy implants or periodontitis were considered eligible for inclusion.

290 Fifty-five adults with moderate-to-severe periodontitis were enrolled in a randomized, 3-month dou

291 Some species generally associated with periodontitis were found to a greater extent in patients

292 eighty-four patients with moderate-to-severe periodontitis were randomly allocated to one of four tre

293 Twenty-six patients (52 sites) with chronic periodontitis were treated either with autologous PRF wi

294 proteinase (MMP)-8, a biomarker candidate of periodontitis, were determined in 48 patients (29 patien

295 1) Clinical situation: In patients with periodontitis, what (if any) clinical situations/conditi

296 Periodontitis, which is the sixth most prevalent infecti

297 Healthy participants without periodontitis with at least two teeth showing PreGR >/=2

298 results link the systemic effects of induced periodontitis with changes in hepatic tissues such as mi

299 be used to inhibit induction of experimental periodontitis with favorable handling and inflammation-r

300 has been associated with the pathogenesis of periodontitis with severe alveolar bone destruction.