ライフサイエンスコーパス: peripheral blood T cell

1 d genes the most overexpressed compared with peripheral blood T cells.

2 As with nuclear extracts of freshly isolated peripheral blood T cells.

3 enous IL-4 gene expression in nontransformed peripheral blood T cells.

4 eta3 Ab that activates approximately 3-5% of peripheral blood T cells.

5 of IL-2-responsiveness in mitogen-stimulated peripheral blood T cells.

6 ness from freshly isolated CD4(+) and CD8(+) peripheral blood T cells.

7 at compartment and differ from those seen in peripheral blood T cells.

8 man T cell lymphoma, as well as in activated peripheral blood T cells.

9 he surface of a subset (10-15%) of activated peripheral blood T cells.

10 h CCR6 being the only MIP-3alpha receptor on peripheral blood T cells.

11 ral killer (NK) cells, and the Th2 subset of peripheral blood T cells.

12 dition, BY55 was expressed on most CD8+CD28- peripheral blood T cells.

13 on of T cell clones and Ag- or PHA-activated peripheral blood T cells.

14 ceptor family, LT beta R is not expressed by peripheral blood T cells.

15 was also reduced, as was IL-2 production by peripheral blood T cells.

16 ative TCR-beta chain sequences in their CD4+ peripheral blood T cells.

17 ading to enhanced proliferation of purified, peripheral blood T cells.

18 mation is associated with expansions of CD4+ peripheral blood T cells.

19 cytokines as well as cytokine expression in peripheral blood T cells.

20 the inhibitory receptor PD-1 in FL TILs and peripheral blood T cells.

21 and ultimately Th2 cell development in human peripheral blood T cells.

22 otein and to CD28 expressed on CD4+ and CD8+ peripheral blood T cells.

23 of MLL, Th2 cell maturation in primary human peripheral blood T cells.

24 cted (or were detected only occasionally) in peripheral blood T cells.

25 yze the regulation and role of iNOS in human peripheral blood T cells.

26 ar cell tumor tissue can induce apoptosis in peripheral blood T cells.

27 r low pH affected TCR signaling potential of peripheral blood T cells.

28 hocytic leukemia (B-CLL) but not in T-CLL or peripheral blood T cells.

29 long with HTLV-I-mediated infection of human peripheral blood T-cells.

30 hat is expressed constitutively on all human peripheral-blood T cells.

31 gene variations, from virus detected in the peripheral blood T cells 19 months earlier.

32 ell clones; this was also observed in CD8(+) peripheral blood T cells activated with TCR cross-linkin

33 myeloid leukemia (AML) myeloblasts inhibits peripheral blood T cell activation and proliferation, re

34 Disproportionately large fractions of peripheral blood T cells also express IGF-1R in patients

35 4) Purified gp180 can bind to peripheral blood T cells and activate p56(lck).

36 ions were performed combining enriched human peripheral blood T cells and allogeneic HK or HF with or

37 l roles in antigen-mediated proliferation of peripheral blood T cells and also is critical for activa

38 Peripheral blood T cells and antigen-presenting cells fr

39 Restoration of normal numbers of peripheral blood T cells and B cells among recipients of

40 CAR T cells are generated from the patient's peripheral blood T cells and expand in the recipient to

41 stic T-cell lines and lower levels in normal peripheral blood T cells and hyperplastic tonsil.

42 ptor (TCR) following CD3 triggering in human peripheral blood T cells and is rapidly and reversibly t

43 reatment followed robust elimination of both peripheral blood T cells and lymph node T cells.

44 The LXA(4) receptor (ALX) is expressed in peripheral blood T cells and mediates the inhibition of

45 al decreases in the absolute number of total peripheral blood T cells and most Vbeta TcR+ subsets.

46 -22-producing CD4(+) and CD8(+) T cells from peripheral blood T cells and naive CD4(+) T cells in mix

47 lso induced secretion of IFN-gamma from both peripheral blood T cells and NK cells, and IFN-gamma mRN

48 -18 to augment IFN-gamma production in human peripheral blood T cells and NK cells.

49 characterize the expression of DORs by human peripheral blood T cells and to determine whether a spec

50 r was compromised in both Zap70 knocked down peripheral blood T cells and Zap70 or Lck-deficient/Lck-

51 letion of Jarid1b from bone marrow increased peripheral blood T cells and, following secondary transp

52 B/SOCS1/SSI-1 is strongly induced by IL-2 in peripheral blood T cells, and JAB/SOCS1/SSI-1 overexpres

53 These different mechanisms of peripheral blood T cell apoptosis may play different rol

54 Although peripheral blood T cells are largely unresponsive to the

55 In this study, we used normal peripheral blood T cells, as well as caspase-8-, caspase

56 -alpha secretion by the tumor-associated and peripheral blood T cells at baseline, stimulation with a

57 ht a potential for IL6 signaling response in peripheral blood T cells at diagnosis as a predictive bi

58 Importantly, defective IL6 signaling in peripheral blood T cells at diagnosis correlated with wo

59 mutation in genomic DNA of individual sorted peripheral blood T cells, B cells, and monocytes in pati

60 nstitutive and relatively high expression in peripheral blood T cells, B cells, and monocytes.

61 that CXCR7 protein is not expressed by human peripheral blood T cells, B cells, NK cells, or monocyte

62 About 5% of peripheral blood T cells bear gammadelta TCRs, most of w

63 Studies of peripheral blood T cells before and after patch testing

64 These cells make up 2-5% percent of human peripheral blood T cells but expand to make up 8-60% of

65 beta-Catenin is not detectable in normal peripheral blood T cells but is expressed in T-acute lym

66 y results in uniform CAR expression in human peripheral blood T cells, but also enhances T-cell poten

67 PMCH is not expressed in peripheral blood T cells, but expression is highly induc

68 Foreskin T cells were more activated than peripheral blood T cells, but foreskin T cells were not

69 level TCR thymocytes was similar to that on peripheral blood T cells, but was much lower than that o

70 lated tonsillar B cells and at low levels in peripheral blood T cells, but was not expressed in any o

71 Costimulation of human peripheral blood T cells by CD3 mAb OKT3 in conjunction

72 Expression of CD30L can be induced in peripheral blood T cells by cross-linking the CD3 compon

73 Infusions of donor peripheral blood T cells can induce durable remissions o

74 Cultured peripheral-blood T cells can be differentiated into CLA-

75 If RA synovial tissue T cells, like normal peripheral blood T cells, can respond to superantigens p

76 le, we show that activation of resting human peripheral blood T cells caused downregulation of Mfn2 l

77 A human peripheral blood T cell cDNA expression library was scre

78 mannan (LAM) could specifically induce human peripheral blood T cell chemotaxis in vitro.

79 ipoarabinomannan (ManLAM) could induce human peripheral blood T cell chemotaxis.

80 Among normal peripheral blood T cells, CLA expression was essentially

81 DNA extracted from individually plucked peripheral blood T cell colonies and marrow colony-formi

82 ystemic obesity-related abnormalities in the peripheral blood T-cell compartment are not well defined

83 In this study, we investigated the peripheral blood T-cell compartment of morbidly obese an

84 The peripheral blood T-cell compartment of morbidly obese su

85 nospot assay (ELISPOT) analysis of psoriatic peripheral blood T cells confirmed that these autoantige

86 ate that expression of CD69 on CD3+ and CD8+ peripheral blood T cells correlates closely with the pre

87 but resulted in only transient increases in peripheral blood T cell counts.

88 Mixed peripheral blood T cells cultured on the stiffer substra

89 of IL-6 and interleukin 1beta (IL-1beta) on peripheral blood T-cell cycling and CD127 surface expres

90 Repeated spirometry, 6MWD, and peripheral blood T-cell cytokine responses to lung elast

91 e Jurkat human T lymphoma cell line or human peripheral blood T cells disrupted TCR-induced actin pol

92 blood T cells but expand to make up 8-60% of peripheral blood T cells during bacterial and parasitic

93 FTY720-driven splenic and peripheral blood T cell egress are both independent of C

94 n healthy S aureus carriers and noncarriers, peripheral blood T cells elaborated TH2 cytokines after

95 Peripheral blood T cells exhibited this defect only in p

96 Peripheral blood T cells exposed to suboptimal concentra

97 that a disproportionately large fraction of peripheral blood T cells express IGF-1R (CD3+IGF-R+).

98 ression by four- to sixfold on CD8- and CD8+ peripheral blood T cells following PHA activation.

99 pretreated ocular cells with activated human peripheral blood T cells for 48 hours and assessing T-ce

100 Peripheral blood T cells from 34 patients with stable an

101 rejection, we have evaluated the response of peripheral blood T cells from 50 heart transplant recipi

102 IFN-gamma production by CD4(+) and CD8(+) peripheral blood T cells from 58 high-risk women was mea

103 one (HC/2G-1) was established by stimulating peripheral blood T cells from a patient with renal cell

104 y were demonstrable in purified unstimulated peripheral blood T cells from approximately 30% (5/16) o

105 Peripheral blood T cells from egg allergic patients were

106 n a large proportion of V gamma 9+V delta 2+ peripheral blood T cells from healthy subjects (30-45%)

107 In M. tuberculosis-stimulated peripheral blood T cells from healthy tuberculin reactor

108 vitro replicative capacity were assessed in peripheral blood T cells from HIV+ and HIV- donors.

109 duced T cell apoptosis is Fas independent in peripheral blood T cells from HIV+ individuals.

110 Peripheral blood T cells from individuals carrying the A

111 e numbers of tumour-infiltrating and matched peripheral blood T cells from individuals with cancer.

112 e for polarized type 2 T-cell responses, and peripheral blood T cells from most human donors recogniz

113 Peripheral blood T cells from NMO patients and HC were e

114 s conducted with murine cells, we stimulated peripheral blood T cells from normal human beings in vit

115 onal Kv1.3 channels in TILs as compared with peripheral blood T cells from paired patients, which was

116 tion of the transcription factor NFkappaB in peripheral blood T cells from patients with renal cell c

117 compared global gene expression profiles of peripheral blood T cells from previously untreated patie

118 This activation scheme was repeated on peripheral blood T cells from psoriatic patients versus

119 Using peripheral blood T cells from recipients of HLA-identica

120 ls to release TNF-alpha when cocultured with peripheral blood T cells from rheumatoid patients.

121 triction was not found in mitogen-stimulated peripheral blood T cells from the major donor of the CTL

122 ng of the PCR amplification products of CD4+ peripheral blood T cells from the subjects with ulcerati

123 Both CD4+ and CD8+ peripheral blood T cells from these earlier stage patien

124 inhibited the allergen-induced activation of peripheral blood T cells from those subjects.

125 In M. tuberculosis-stimulated peripheral blood T cells from tuberculosis patients, ant

126 ed the ability of recombinant G-CSF to alter peripheral blood T-cell function and graft-versus-host d

127 h2 cells when cocultured with purified human peripheral blood T cells, further indicating functional

128 that these requirements are met by expanding peripheral blood T cells genetically targeted to the CD1

129 Apoptosis of peripheral blood T cells has been suggested to play an i

130 In rheumatoid arthritis, peripheral blood T cells have age-inappropriate telomeri

131 hGITR mRNA in tissues were generally low; in peripheral blood T cells, however, antigen-receptor stim

132 he Fc gammaR1 STAT site also occurs in human peripheral blood T cells immortalized with HTLV-I in vit

133 eciprocal expression of CXCR4 and CCR5 among peripheral blood T cells implies distinct susceptibility

134 n of anti-CD3 mAb-activated, highly purified peripheral blood T cells in an IL-2-dependent, cyclospor

135 Approximately 4% of peripheral blood T cells in humans express a T cell rece

136 Peripheral blood T cells in patients with paroxysmal noc

137 Tck cells were generated by culture of peripheral blood T cells in the presence of interleukin-

138 ferentiation model of freshly isolated human peripheral blood T cells in which IFN-gamma was used as

139 gammadelta T cells are the majority peripheral blood T cells in young cattle.

140 magglutinin-inducible proliferation in human peripheral blood T-cells in a dose-dependent manner.

141 induced apoptosis of the patient's malignant peripheral blood T-cells in vitro.

142 mma (IFN gamma), were cultured with purified peripheral blood T cells, in the presence or absence of

143 at CCR7 is expressed on the vast majority of peripheral blood T cells, including most cells that expr

144 highest levels of serum IgE and by increased peripheral blood T-cell interleukin-4 (IL-4) production.

145 d differentiation of CB naive, but not adult peripheral blood, T cells into immune-suppressive Tregs,

146 Here, we show the IL6 signaling response in peripheral blood T cells is impaired in breast cancer pa

147 (ICs), the trigger for alterations in human peripheral blood T cells is poorly understood.

148 Compared with matched peripheral blood T cell lines, primary IHL lines from pa

149 We demonstrate in peripheral blood T cell lymphoblasts that immediate earl

150 lls express EPAC1 transcript, whereas T-CLL, peripheral blood T cells, monocytes, and neutrophils do

151 c mechanisms might be acting to preserve the peripheral blood T-cell numbers in patients.

152 Peripheral blood T cells of 21 of 33 patients reacted to

153 We found that mitogen-stimulated peripheral blood T cells of asthmatic subjects expressed

154 Peripheral blood T cells of eight SMS patients recognise

155 We analyzed peripheral blood T cells of patients with CTCL with stag

156 also expressed in a second joint, but not in peripheral blood T cells of the same individual.

157 pitope from human GAD65 were used to analyze peripheral blood T-cells of newly diagnosed type 1 diabe

158 tal injection of graft recipients with donor peripheral blood, T cells, or B cells 7 days before tran

159 ness after TCR engagement when compared with peripheral blood T cell (PBT).

160 The activation and differentiation of peripheral blood T cells (PBT) are known to correlate wi

161 First, in human peripheral blood T cells (PBT), expression of MKP6 is st

162 compared the cell cycle kinetics of LPTs and peripheral blood T cells (PBTs) before and after CD3- an

163 eatment levels of programmed death-1 (PD-1)+ peripheral blood T cells (PD-1+ cluster of differentiati

164 lthy individuals, BLT1(+) T cells are a rare peripheral blood T-cell population enriched for the acti

165 ific chemoattractant receptors compared with peripheral blood T cells prechallenge, including CCR5, C

166 In highly infected peripheral blood T cells, profound necrosis occurred equ

167 Human peripheral blood T cells proliferate in response to Esch

168 In contrast to CCR9(-), CCR9(+)CD4(+) peripheral blood T cells proliferate to anti-CD3 or anti

169 ugh PBMC-derived APCs and DCs both supported peripheral blood T cell proliferation when primed with f

170 The peripheral blood T cell proliferative responses induced

171 of the inconsistency in published studies of peripheral blood T-cell reactivity to islet autoantigens

172 t and (2) determine whether intratumoral and peripheral blood T cell receptor (TCR) clonality inform

173 amma2Vdelta2 T cells comprise 2%-5% of human peripheral blood T cells, recognize ubiquitous nonpeptid

174 se to a microbial pathogen, we evaluated the peripheral blood T cell response to M. tuberculosis in h

175 Thymidine incorporation assays also showed a peripheral blood T-cell response to rhGM-CSF in at least

176 Peripheral blood T cell responses in the lepromatous for

177 To assess peripheral blood T cell responses to Jo-1, we first subc

178 ed systemic responses involving serum Ab and peripheral blood T cell responses.

179 Peripheral blood T-cell responses are used as biomarkers

180 , we detected HIV-specific CD4(+) and CD8(+) peripheral blood T-cell responses in 10%-20% of 247 subj

181 irpin RNA-mediated knockdown of Itk in human peripheral blood T cells results in increased expression

182 Activation of peripheral blood T cells results in the mannose 6 phosph

183 ly, ex vivo analysis of human thymocytes and peripheral blood T cells revealed that human RTE and new

184 a chain V region families from CD4+ and CD8+ peripheral blood T cells showed a skewed distribution in

185 Gene expression analysis of human peripheral blood T cells showed that numerous genes asso

186 hanced Th2 response has not been detected in peripheral blood T cells stimulated in vitro with Mycoba

187 tant NFAT complex in the nuclear extracts of peripheral blood T cells stimulated with PMA plus alphaC

188 Peripheral blood T cells stimulated with PMA/alphaCD28 p

189 The impact of intrinsic aging upon human peripheral blood T cell subsets remains incompletely qua

190 mphotropic virus type I (HTLV-I) infections, peripheral blood T cell subsets were analyzed by using a

191 We analyzed CD30 expression on peripheral blood T-cell subsets and soluble CD30 levels

192 n restore proliferation of tumor-derived and peripheral blood T-cell subsets, D-1MT does not effectiv

193 to explain several well-described defects in peripheral blood T cells, such as reduction in expressio

194 ion on intestinal CD4(+) T cells, but not on peripheral blood T cells, suggesting a gut-specific, Ag-

195 patients expressed higher levels of CD24 on peripheral blood T cells than did the CD24a/a patients.

196 In this work, we show that human peripheral blood T cells that are stimulated through the

197 elta2 T cells comprise a small population of peripheral blood T cells that in many infectious disease

198 ed by mass spectrometry as abundant in human peripheral blood T cells that is preferentially expresse

199 flammatory cytokines because we demonstrated peripheral blood T cells that produced TNF and IFNgamma

200 aining eight patients, seven had recovery of peripheral-blood T cells that were functional and led to

201 However, unlike peripheral blood T cells, the majority of foreskin T cel

202 When combined with the changes in peripheral blood T cells, these factors indicate that ev

203 pendent primary adhesion is induced in human peripheral blood T cells through T cell receptor trigger

204 28 augmentation of TCR-mediated signaling in peripheral blood T cells through transcriptional activat

205 In vitro, Eap reduced adhesion of peripheral blood T cells to immobilized ICAM-1 as well a

206 tudy we measured the ability of lesional and peripheral blood T cells to produce intracellular interf

207 roarray analysis to characterize early human peripheral blood T cell transcriptional responses follow

208 Peripheral blood T cells transduced with a lentiviral ve

209 ic lymphocytic leukemia (CLL) cells, but not peripheral blood T cells, undergo apoptosis following tr

210 CX(3)CR1 expression on peripheral blood T cells was analyzed by flow cytometry.

211 Using purified human CD4+ peripheral blood T cells, we show that CD28 stimulation

212 Isolated trauma patients' and controls' peripheral blood T cells were assayed for negative and p

213 The peripheral blood T cells were at least 30 times more pot

214 ly expanded TCR-beta chain sequences of CD4+ peripheral blood T cells were identifiable in genomic DN

215 Purified peripheral blood T cells were induced to proliferate in

216 Positively selected CD4+ and CD8+ peripheral blood T cells were isolated from subjects wit

217 ative TCR-beta chain sequences from the CD4+ peripheral blood T cells were persistent over at least a

218 ration signal, whereas mature thymocytes and peripheral blood T cells were sensitive.

219 Peripheral blood T cells were stimulated with Chinese ha

220 patient with Sezary syndrome whose malignant peripheral blood T cells were TCRVbeta17+.

221 ts have a higher frequency of IL-4-producing peripheral blood T cell when compared to normal subjects

222 Stimulation of human peripheral blood T cells with mitogenic pairs of anti-CD

223 phosphatase, MKP-2, that is induced in human peripheral blood T cells with phorbol 12-myristate 13-ac

224 ed IL-2 production after activation of human peripheral blood T cells with phorbol ester (PMA) and an