ライフサイエンスコーパス: peripheral organ

1 systems, including the spinal cord and other peripheral organs.

2 ribution of (18)F-FHNP and (18)F-FES in most peripheral organs.

3 ent signals to circadian clocks in mammalian peripheral organs.

4 mmune response to intracellular infection in peripheral organs.

5 nantly in enterohepatic tissues, but also in peripheral organs.

6 ells from other secondary lymphoid organs or peripheral organs.

7 ed by humoral and cellular autoreactivity to peripheral organs.

8 tics of (11)C-d-methamphetamine in brain and peripheral organs.

9 y high levels of viremia and virus titers in peripheral organs.

10 ole in the inhibition of T-cell responses in peripheral organs.

11 nstitutive IL-4 and IFN-gamma transcripts in peripheral organs.

12 -, L-selectin-) mediating immune response in peripheral organs.

13 rase (NADPH-d) histochemistry in the CNS and peripheral organs.

14 - animals lacked NKT cells in the thymus and peripheral organs.

15 her smokers would also have reduced MAO A in peripheral organs.

16 ) rhythms are expressed in a wide variety of peripheral organs.

17 cantly decreased in the neocortex but not in peripheral organs.

18 mokers would also have reduced MAO levels in peripheral organs.

19 alformations without overt histopathology of peripheral organs.

20 but substantial amounts are also present in peripheral organs.

21 gnificant increases in glucose metabolism in peripheral organs.

22 the central nervous system and in most major peripheral organs.

23 d is also an important detoxifying enzyme in peripheral organs.

24 was high in brain with much lower levels in peripheral organs.

25 (-)B220(+) (double-negative [DN]) T cells in peripheral organs.

26 n rhythms of gene expression occur widely in peripheral organs.

27 pt upregulation of inflammatory mediators on peripheral organs.

28 n composition of the brain or alterations in peripheral organs.

29 B7 suggests increased immunogenicity of the peripheral organs.

30 o dietary factors and metabolic signals from peripheral organs.

31 selected by self Ag/MHC and emigrate to the peripheral organs.

32 es develop within the thymus and emigrate to peripheral organs.

33 and enhanced bacterial clearance in multiple peripheral organs.

34 bone marrow (BM) before they migrate out to peripheral organs.

35 g their trafficking from the blood stream to peripheral organs.

36 ecific epigenome plasticity in the brain and peripheral organs.

37 cetylcholinesterase density in the brain and peripheral organs.

38 grate toward infected cells after entry into peripheral organs.

39 ass at a very early stage and disseminate to peripheral organs.

40 Cat2 expression is not induced in MDSCs in peripheral organs.

41 or imaging acetylcholinesterase densities in peripheral organs.

42 l replication and associated pathogenesis in peripheral organs.

43 es and an impaired CD4(+) T cell response in peripheral organs.

44 ial innervation and blood flow regulation in peripheral organs.

45 hough there was no dissemination of fungi to peripheral organs.

46 ut little effort has been devoted to imaging peripheral organs.

47 tres in the spleen and the spread of LCMV to peripheral organs.

48 prevents pathogenic herpesvirus infection in peripheral organs.

49 toxic T cell differentiation in lymphoid and peripheral organs.

50 effector-memory phenotype and enrichment in peripheral organs.

51 ese mice was markedly enhanced in thymus and peripheral organs.

52 he thymus and for Th2 differentiation in the peripheral organs.

53 ing but could not detect specific binding in peripheral organs.

54 In contrast, LVsp2 disseminated better to peripheral organs.

55 These findings indicate that central and peripheral organs accommodate selection and peripheral s

56 CD8 T cells persist at high frequencies in peripheral organs after resolution of an immune response

57 omplex array of metabolic signals, sensed by peripheral organs along with specific locations within t

58 indotricarbocyanine iodide-labeled hADSCs in peripheral organs and brain after TBI.

59 Thus, HSPCs can survey peripheral organs and can foster the local production of

60 ssociated with greater virus accumulation in peripheral organs and central nervous system tissues.

61 ulation of memory T cells remains present in peripheral organs and contributes to the control of seco

62 r in the intestine, fail to export copper to peripheral organs and die a few weeks after birth.

63 absence of detectable organic disease in the peripheral organs and may cause normal or physiologic co

64 r regulator of thermogenesis, acting both in peripheral organs and on central autonomic pathways.

65 splayed significantly reduced viral loads in peripheral organs and showed prolonged survival.

66 gy homeostasis and communication between the peripheral organs and the brain.

67 In mice, the mutant poorly disseminated to peripheral organs and the production of proinflammatory

68 sistency of oscillator properties in various peripheral organs and tissues from the period3-luciferas

69 y in the central nervous system, but also in peripheral organs and tissues.

70 unication link between our brain and several peripheral organs and tissues.

71 mine and (-)-cocaine in the baboon brain and peripheral organs and to assess the saturability and pha

72 -fold higher in the brain than in any tested peripheral organs and was at its highest 24h following t

73 rtality by restricting virus accumulation in peripheral organs and, subsequently, in central nervous

74 survival, more rapid fungal clearance in key peripheral organs, and an altered inflammatory response.

75 Cytogenesis in adult peripheral organs, and in all organs during development,

76 mation, increased bacterial dissemination to peripheral organs, and increased host mortality.

77 Virus titers in serum, peripheral organs, and the brain were similar in V3000-

78 easured their localization in blood, various peripheral organs, and whole and capillary-depleted brai

79 ting hormones whose actions were confined to peripheral organs, are now known to be released in the b

80 As are endogenously present in rat brain and peripheral organs as determined via targeted lipidomics

81 in gamma delta T cell production extends to peripheral organs as IL-7 -/- mice are essentially devoi

82 Because smoking exposes peripheral organs as well as the brain to MAO A-inhibito

83 Because smoking exposes peripheral organs as well as the brain to MAO-inhibitory

84 infection of lung tissue in BALB/c mice and peripheral organs at low doses.

85 al disease with high viral multiplication in peripheral organs, but mu11E10 produced nonfatal infecti

86 bone marrow and complete their maturation in peripheral organs, but the molecular events controlling

87 ssion of circadian oscillations in different peripheral organs by diverse pathways.

88 genous cinnabarinic acid in brain tissue and peripheral organs by high-performance liquid chromatogra

89 decreases bacterial burden in the lungs and peripheral organs by potentiating C3 opsonization on bac

90 of systemic inflammation and sepsis involves peripheral organs, causing gastrointestinal, renal, and

91 stigated whether excitotoxicity may occur in peripheral organs, causing tissue injury, and report tha

92 rresponding decrease in monocyte uptake into peripheral organs compared to nontransgenic littermates.

93 showed that V3043 replication was reduced in peripheral organs compared to that of V3000, titers in s

94 ice were found higher in the BM but lower in peripheral organs compared with control littermates, ind

95 In sensory systems, peripheral organs convey sensory inputs to relay network

96 and more broadly emphasize the importance of peripheral organ damage as a possible mechanism that med

97 ct in NK cell numbers in the bone marrow and peripheral organs despite increased proliferation and in

98 These findings confirm that peripheral organs differ in their response to SCN-depend

99 lrp2) are activated in a circadian manner in peripheral organs during 12 h dark:12 h dark (DD) but no

100 diating essential Notch signaling in several peripheral organs during pharmacological inhibition of P

101 The 2 drugs showed similar behavior in all peripheral organs examined except the kidneys and pancre

102 equency because of reduced glucose uptake in peripheral organs, excessive hepatic glucose production,

103 In addition, peripheral organs expressed tissue-specific differences

104 y scans showed radioactivity in brain and in peripheral organs expressing NOP receptors, such as hear

105 Activation of peripheral organs following explosive brain death may be

106 entrations of five brain regions and of four peripheral organs from 5 months old, male and female, wi

107 exhibit diversity in studies of central and peripheral organ function and disease.

108 wild-type levels, and by 8 months of age all peripheral organs had accumulated sphingomyelin and demo

109 would parallel that of sexual behaviors and peripheral organs has so far uncovered modest quantitati

110 In peripheral organs, immune complexes engage the complemen

111 We measured MAO A in peripheral organs in a group of 9 smokers and compared i

112 itic cells or macrophages and recruitment to peripheral organs in chronic inflammatory diseases are d

113 estigate the feasibility of imaging MAO B in peripheral organs in humans with PET.

114 tobacco smoke exposure on MAO B activity in peripheral organs in humans.

115 Here we compared MAO B in peripheral organs in nonsmokers and smokers by using pos

116 lts in a systemic increase of neutrophils in peripheral organs in the absence of histological inflamm

117 mine and (11)C-(-)-cocaine in both brain and peripheral organs in the same animal.

118 of viral load in circulating blood cells and peripheral organs in the two groups, WNV-infected polymo

119 atively at P15 in sympathetically innervated peripheral organs, in sympathetic ganglia, in adrenal gl

120 n neurons and nonneuronal cells in brain and peripheral organs including sperm, eggs, and preimplanta

121 age [CFU-GEMM]) from the bone marrow (BM) to peripheral organs, including blood, and also increases t

122 of prion protein amyloid was seen throughout peripheral organs, including the bowel and peripheral ne

123 prepared from the central nervous system and peripheral organs, including the buccal muscles, esophag

124 pheral beta-adrenergic receptor signaling in peripheral organs, including the gastrointestinal tract.

125 to amylin accumulation and proteotoxicity in peripheral organs, including the heart.

126 or imaging acetylcholinesterase densities in peripheral organs, including the salivary glands, heart,

127 ly harmful stimulation of estrogen-sensitive peripheral organs, including the uterus and the anterior

128 were also observed in another mouse model of peripheral organ inflammation (i.e., 2,4-dinitrobenzene

129 ur observations provide a clear link between peripheral organ inflammation and cerebral changes that

130 rain communication pathway in the setting of peripheral organ inflammation whereby monocytes are recr

131 central neurotransmission, the link between peripheral organ inflammation, circulating cytokine sign

132 inflammatory response in hippocampus during peripheral organ inflammation.

133 The reproductive tract tissues and peripheral organs integrated into a microfluidic platfor

134 The altered trafficking of NK cells from peripheral organs into the blood was due to selective hy

135 as significant effects on the function(s) of peripheral organs involved in maintaining body compositi

136 e the peptide repertoire in both central and peripheral organs is nearly the same, interactions of th

137 The repertoire of T lymphocytes available in peripheral organs is tuned in the thymus.

138 ly labeled BMSCs traveled to and remained in peripheral organs (lungs, spleen, liver) 3 days after IV

139 el through the blood and replace cDCs in the peripheral organs, maintaining homeostasis of the highly

140 ite stable donor blood pressure, ischemia of peripheral organs may explain in part the increased inci

141 pling the spread of the double mutant to the peripheral organs of animals and by inducing cytokine/ch

142 NOS in sensory areas both in the CNS and the peripheral organs of Aplysia and implies a role for NO a

143 ies demonstrate that neutrophils increase in peripheral organs of B7-H4KO mice more so than their lit

144 Tissue-specific expression in brain and peripheral organs of different exogenous genes (beta-gal

145 lar to that in the brain was observed in the peripheral organs of LCMV-infected mice.

146 sibly disappear from the spleens, blood, and peripheral organs of mice early after infection with Lis

147 KT2, and NKT17 sublineages in the thymus and peripheral organs of naive mice.

148 eyes and olfactory terminals, as well as in peripheral organs of Parkinsonian patients.

149 serotonin (5-HT)-immunoreactive elements in peripheral organs of the sea-slugs Pleurobranchaea calif

150 he vagus nerve and was not observed in other peripheral organs or in brain regions that control feedi

151 smokers have significantly reduced MAO B in peripheral organs, particularly in the heart, lungs, and

152 FN4-expressing cells from the bone marrow to peripheral organs predicts preneoplastic changes in the

153 ariety of proteins, including those that are peripheral organ-specific and are not expressed by other

154 so rhythmic expression of these genes in all peripheral organs studied.

155 TCF7L2 is important in the development of peripheral organs such as adipocytes, pancreas, and the

156 ators of lipid-induced insulin resistance in peripheral organs such as muscle.

157 Extramedullary myelopoiesis occurs in peripheral organs such as spleen and produces many types

158 of lung involvement (L), and malfunction of peripheral organs such as the kidney, liver, and brain (

159 daily cellular metabolic cycles, imposing on peripheral organs such as the liver a strict programme t

160 cells are found in the thymus as well as in peripheral organs such as the liver, spleen, and bone ma

161 dies have examined the effect of morphine on peripheral organs, such as the heart, in morphine-tolera

162 in the brain is set by light, pacemakers in peripheral organs, such as the liver, are reset by food

163 lized time keepers in the brain, but also in peripheral organs, suggesting that the ability to keep t

164 In several peripheral organ systems, including lung and gut, we obs

165 n mediating sympathetic neurotransmission in peripheral organ systems; however, central alpha1ARs are

166 In peripheral organs, T cell-specific ablation of Vps34 had

167 -induced functional impairments in the major peripheral organs that control energy flux: adipose tiss

168 in modulating the host antiviral response in peripheral organs that controls bunyavirus neuroinvasion

169 In contrast to vessels of peripheral organs, the BBB limits the exchange of inflam

170 the vector and damages local tissue in many peripheral organs, the immune response to adenovirus in

171 ne intestines without effecting migration to peripheral organs; this suggests that alpha4beta7-select

172 (zeitgebers) for the circadian clock within peripheral organs through the activation of tissue-speci

173 tory mediators and cell surface molecules in peripheral organs to be engrafted, making them more pron

174 anticipated cross-talk between the liver and peripheral organs to influence insulin sensitivity, prob

175 by adipose tissue and acts in the brain and peripheral organs to regulate glucose and lipid metaboli

176 central integrator of metabolic signals from peripheral organs to the brain, which would represent a

177 hypothesis that the flow of sterol from the peripheral organs to the liver is dependent upon circula

178 the centripetal flux of cholesterol from the peripheral organs to the liver was essentially constant

179 higher titers than the sigma1s-null virus in peripheral organs to which reovirus spreads via the bloo

180 re able to rapidly eradicate Vacc-IND-G from peripheral organs, to mediate delayed-type hypersensitiv

181 brain death is a significant risk factor for peripheral organs used for transplantation.

182 Pres accumulation in the spleen and in other peripheral organs was first monitored to describe the ea

183 his central catastrophe and its influence on peripheral organs, we have established a reproduceable m

184 bacteria loads in the intestinal mucosa and peripheral organs were elevated in Lpa1(-/-) mice.

185 ayed dissemination of bacteria from lungs to peripheral organs were observed in BKO mice.

186 -derived dendritic cell (DC) precursors seed peripheral organs, where they encounter diverse cellular

187 BM, enter the blood, and traffic to multiple peripheral organs, where they reside for at least 36 hr

188 dritic cell-derived IFN-I primarily protects peripheral organs, whereas concomitant TLR and RLH signa

189 suppressed T-cell development in thymus and peripheral organs, whereas deletion of Rac1 moderately a

190 s on average 17-fold higher in brain than in peripheral organs, whereas JNK protein levels were simil

191 ction, NF1 selectively disseminated to mouse peripheral organs, whereas the other strains (NF2, NF3,

192 s the master circadian pacemaker, entraining peripheral organs which also demonstrate circadian rhyth

193 e was associated with increased infection in peripheral organs, which resulted in higher virus titers

194 nt and gives rise to a severe lymphopenia in peripheral organs, while also leading to pro-B cell line

195 m 60 to 120 min after injection in brain and peripheral organs with high TSPO densities such as lung

196 ding (dissociation constant, 6-39 nM) in pig peripheral organs with low nonspecific signal.

197 on of T cells and defective early seeding of peripheral organs with regulatory T cells (Tregs).

198 tissue lymphatic vasculature that exists in peripheral organs with the proposed function of meningea

199 s with SIVE had more infected macrophages in peripheral organs, with the exception of lymph nodes.

200 hologic amyloid accumulates in the CNS or in peripheral organs, yet the mechanism underlying the targ