ライフサイエンスコーパス: periplasm

1 (FBPase) are in the extracellular fraction (periplasm).

2 and Ag(I) to the CusCBA transporter from the periplasm.

3 domain remains unfolded until it reaches the periplasm.

4 alysis of oxidative folding in the bacterial periplasm.

5 domains of the FtsB and FtsL proteins in the periplasm.

6 studies suggested that BB0744 resides in the periplasm.

7 f pre-folded, fully active endolysins to the periplasm.

8 coil-coiled platform spanning the bacterial periplasm.

9 ure of MalK2 and opening of MalFG toward the periplasm.

10 nown for disulfide bond isomerization in the periplasm.

11 hoQ is activated by different signals in the periplasm.

12 is connected to a cage-like vestibule in the periplasm.

13 ulfide bond catalyst DsbA, LacZ folds in the periplasm.

14 e and the C-terminal signaling domain in the periplasm.

15 erophore enterobactin, which collects in the periplasm.

16 YfiR disulfide bonds stabilized YfiR in the periplasm.

17 (-1), respectively, and was localized in the periplasm.

18 metal ion transfer from CusF to CusA in the periplasm.

19 eously occurring OMP folding reaction in the periplasm.

20 -length protein remained inactive in E. coli periplasm.

21 urface-exposed, while MOSP(N) resides in the periplasm.

22 abolic enzyme in that it is localized in the periplasm.

23 ing intact the inner and outer membranes and periplasm.

24 the cytoplasmic membrane into the bacterial periplasm.

25 ulating FMN and FAD levels in the treponemal periplasm.

26 ibly acts by oxidation of toxic Cu(I) in the periplasm.

27 ine binding protein (LBP) from the bacterial periplasm.

28 rojection of the N-terminal domains into the periplasm.

29 with a pseudopilus structure that spans the periplasm.

30 carbon dioxide, which buffer the pathogen's periplasm.

31 predominant orientation facing in toward the periplasm.

32 a role in sensing or oxidizing metals in the periplasm.

33 nB displaces the N-terminus further into the periplasm.

34 in folding soluble proteins in the bacterial periplasm.

35 ng as the prerequisite to gain access to the periplasm.

36 box and blocks access of the Ton box to the periplasm.

37 unctional due to misfolding in the bacterial periplasm.

38 proteins on disulphide bond formation in the periplasm.

39 xoS sensor through direct interaction in the periplasm.

40 leading to Mn(2+) preloading of PSII in the periplasm.

41 s or released as free oligosaccharide in the periplasm.

42 CPAF is available for processing OmcB in the periplasm.

43 and Rz1 form complexes that span the entire periplasm.

44 the few residues of ExbB known to occupy the periplasm.

45 y electronegative surface of PelC toward the periplasm.

46 s for active transport of nutrients into the periplasm.

47 subset of F-plasmid-encoded proteins in the periplasm.

48 irmed that the protein is transported to the periplasm.

49 oglycan biosynthetic apparatus active in the periplasm.

50 hat occur at the POTRA domain of BamA in the periplasm.

51 o the outer membrane through the hydrophilic periplasm.

52 posed, whereas bound-form Lpp resides in the periplasm.

53 ave focused on soluble LT purified from ETEC periplasm.

54 reporter protein alkaline phosphatase to the periplasm.

55 stant and non-covalently tethered within the periplasm.

56 g that LsrB and Tsr interact directly in the periplasm.

57 of the FeuN polypeptide is localized to the periplasm.

58 P), while SodCI remained tethered within the periplasm.

59 anning the cytoplasm, inner membrane and the periplasm.

60 elp constrain peptidoglycan synthesis in the periplasm.

61 ts confirmed this protein is secreted to the periplasm.

62 e outer leaflet of the inner membrane to the periplasm.

63 can promote disulfide bond formation in the periplasm.

64 physiological importance of the size of the periplasm.

65 rface where the domains meet facing into the periplasm.

66 e and transfers the product, nitrite, to the periplasm.

67 at stall early in the folding process in the periplasm.

68 y coupling motif termed the Ton box into the periplasm.

69 r associated lipoproteins, BamB-BamE, in the periplasm.

70 gene by sensing Mg(2+) concentrations in the periplasm.

71 nked substrates to proteins in the bacterial periplasm.

72 CueP, a major copper-binding protein in the periplasm.

73 eral secretion-mediated translocation to the periplasm.

74 ved to be exclusively located in T. pallidum periplasm.

75 tive environment of the POTRA domains in the periplasm.

76 ope by anchoring the beta-barrels within the periplasm.

77 very of its own TonB1-binding epitope to the periplasm.

78 donuclease activity that is localized to the periplasm.

79 ectively import various C27 sterols into the periplasm.

80 s to modulate pilus assembly from within the periplasm.

81 ked an AT passenger remained unfolded in the periplasm.

82 MOSP(N)-like domains are tethered within the periplasm.

83 tant to a process understood to occur in the periplasm.

84 and a large C-terminal region exposed to the periplasm.

85 mation about flavin utilization in bacterial periplasms.

86 As the polymer passages through the periplasm, 22-44% of the mannuronate residues are conver

87 The OM and the IM are separated by the periplasm, a compartment that contains the peptidoglycan

88 (patA) for translocation of acetate into the periplasm, a PG O-acetyltransferase B (patB) for O-acety

89 ansport protein D) translocates LPS from the periplasm across the outer membrane (OM).

90 rotease resistant and is retained within the periplasm after osmotic shock, a phenomenon that we term

91 s catalyse cytoplasmic Cu(+) efflux into the periplasm, albeit CopA2 at a significantly lower rate.

92 aminopeptidase, PepN, expression of PepN in periplasm allowed us to carry out a quantitative determi

93 ex, where its role is to reorient DPA to the periplasm, allowing this arabinose donor to then be used

94 le compounds are conveyed across the aqueous periplasm along specific molecular transport routes: the

95 We predict that transport of FAD into the periplasm also satisfies the cofactor requirement of the

96 in reducing pathways in the Escherichia coli periplasm, also possess denitrosylating activity.

97 l-asparaginase II localizes primarily to the periplasm and acts together with l-asparaginase I to pro

98 rotein, and similar to BB0323, exists in the periplasm and as a membrane-bound protein.

99 ut how precursors of such proteins cross the periplasm and assemble into the OM.

100 in is localized in the thylakoids and in the periplasm and can be functionally replaced by a plant or

101 omes that are putatively associated with the periplasm and cell surface in a Gram-positive bacterium.

102 libactin) is assembled, transported into the periplasm and cleaved to release the mature product(7-10

103 ependent conformational changes, in both the periplasm and cytoplasm of E. coli.

104 are thought to be distinctly located in the periplasm and cytoplasm respectively.

105 , four interconnected ring structures in the periplasm and cytoplasm, a cytoplasmic disc and dome, an

106 l actively maintains osmotic balance between periplasm and cytoplasm, thus avoiding a substantial pre

107 d AgmU, a protein that localized to both the periplasm and cytoplasm.

108 onnector between the stress responses in the periplasm and cytoplasm.

109 tsKN and other division proteins in both the periplasm and cytoplasm; thus, a clear understanding of

110 lding environment encountered by OMPs in the periplasm and demonstrate the key role of Skp in holding

111 tamase is functional in the Escherichia coli periplasm and enables the bacteria to survive treatment

112 Cellular compartments like periplasm and extracellular medium are difficult to pred

113 independent shuttling of the DNA through the periplasm and into the cytoplasm.

114 asm and involving FtsA, and the other in the periplasm and involving FtsQLB.

115 SodCI is tethered within the periplasm and is protease resistant, thereby remaining t

116 PgaB is located in the periplasm and likely bridges the inner membrane synthesi

117 As these complexes traverse the periplasm and link inner and outer membranes, it remains

118 d/or respond to environmental signals in the periplasm and modulate its biochemical output to OmpR.

119 aggregation-prone curli subunits across the periplasm and outer membrane, and coordinates subunit se

120 s a two-domain protein that localizes to the periplasm and outer membrane.

121 SodCI is both tethered within the periplasm and protease resistant, thereby surviving to d

122 e determined that MarP is located in the Mtb periplasm and showed that this localization is essential

123 g disulfide bond generation in the bacterial periplasm and suggests that the strategy of linked disul

124 lA to the PEL secretion apparatus within the periplasm and that this may allow for efficient deacetyl

125 the F0 proton half-channels that access the periplasm and the cytoplasm are exposed to the same pH,

126 due to protection of the nucleic acid by the periplasm and the extensive cell aggregation that we obs

127 OspC/Vsp1 surface lipoproteins traverse the periplasm and the outer membrane as unfolded monomeric i

128 ciate with additional subunits to bridge the periplasm and the outer membrane.

129 be involved in copper detection in both the periplasm and the thylakoid lumen.

130 in signal transduction between cytoplasm and periplasm and the transition from ExbB homodimers to hom

131 conduit connecting the sensing event in the periplasm and the unleashing of resistance mechanisms in

132 r-membrane proteins (OMPs) accumulate in the periplasm and their C-terminal peptides activate DegS by

133 re leads to premature folding of OspA in the periplasm and thereby prevents secretion through the out

134 itional cytoskeletons, CrvA localizes to the periplasm and thus can be considered a periskeletal elem

135 a low false negative rate, particularly, on "periplasm" and "extracellular medium".

136 er to transport the displayed protein to the periplasm, and a coil-coil arrangement to link the displ

137 he inner membrane (IM), transport across the periplasm, and insertion into the outer leaflet of the O

138 d/or phagocytic proteases gain access to the periplasm, and SodCII is degraded.

139 LsrB binds AI-2 in the periplasm, and Tsr is the l-serine chemoreceptor.

140 sporter, consistent with modification in the periplasm, and was eliminated by deletion of the glucosy

141 d that paramagnetic spin labels entering the periplasm are selectively reduced to achieve specific la

142 escent protein and probe the fluidity of the periplasm as a function of external osmotic conditions.

143 lasmic Fes and IroD, Cee is localized in the periplasm as demonstrated by immunoblotting using Cee-sp

144 rel folding by the Bam complex begins in the periplasm at the membrane interface.

145 s cells that import enterobactin only to the periplasm become morphologically aberrant.

146 The peptidoglycan wall, located in the periplasm between the inner and outer membranes of the c

147 het model where binding of chaperones in the periplasm biases DNA diffusion through a membrane pore i

148 otect the polymer as it passages through the periplasm but that it also plays a role in alginate acet

149 pB strain, suggesting that FeEnt entered the periplasm but then leaked out.

150 sembly is therefore not only arrested in the periplasm, but the preservation of conformational flexib

151 in lacking a classical signal peptide to the periplasm by a SecA-dependent, but SecB-independent targ

152 y, which releases secreted proteins into the periplasm by cleaving the inner membrane-bound leader.

153 n aromatic chromophore that is formed in the periplasm by intramolecular cyclization steps.

154 oxidation of methanol to formaldehyde in the periplasm by methanol dehydrogenase.

155 e monomer that is released normally from the periplasm by osmotic shock.

156 in is displaced from the barrel lumen to the periplasm, concomitant with a marked conformational chan

157 o serine resulted in release of OPH into the periplasm, confirming that OPH is a lipoprotein.

158 s consistent with a net gain of water by the periplasm, decreasing its biopolymer volume fraction.

159 ligosaccharides are further processed in the periplasm, degalactosylated by BoGal36A, and subsequentl

160 suggests how LptD/E can insert LPS from the periplasm directly into the outer leaflet of the OM to e

161 ted Q-site (Q(D)) to proton release into the periplasm during anaerobic respiration.

162 f FBPase were in the extracellular fraction (periplasm) during glucose starvation.

163 iotics that exert activity in the cytosol or periplasm (e.g., ciprofloxacin, spectinomycin, or penici

164 When exported to the Escherichia coli periplasm, each domain disrupted cell growth, and combin

165 large cytoplasm-facing funnel and a smaller periplasm-facing funnel.

166 the structural architecture of an alternate, periplasm-facing state.

167 c N-terminal domains that reach out into the periplasm for communication with the inner membrane plat

168 n this pathogen may confer protection of the periplasm from copper-mediated damage while sustaining v

169 entire sequence of events that occurs in the periplasm from the unfolded-reduced state to the folded-

170 asmolysis), the cytoplasm loses water as the periplasm gains water.

171 ansmembrane domains and a globular domain in periplasm has been recently identified as a CL transport

172 brane to impede entry of vancomycin into the periplasm, hindering access to its target, an intermedia

173 r the aqueous interface of UppP and face the periplasm, implicating that its enzymatic function is on

174 ally not found in bacteriocins targeting the periplasm, implying a specific role in translocating the

175 evoid of export signals, are escorted to the periplasm in a piggyback fashion by the Tat signal pepti

176 ing and transporter specificities within the periplasm in order to maintain transition metal homeosta

177 itor of TMD2 and must be externalized to the periplasm in the lytic pathway.

178 ce for signal transduction from cytoplasm to periplasm in the TonB system.

179 t whereby effectors do not access donor cell periplasm in transit.

180 strate-loaded maltose-binding protein in the periplasm induce a partial closure of the MalK dimer in

181 o four fractions, namely the outer membrane, periplasm, inner membrane, and cytoplasm, and we observe

182 d by AcrB probably from the periplasm or the periplasm/inner membrane interface, and is passed throug

183 be useful in removing O2 from the bacterial periplasm; instead, the four-electron reduction of molec

184 r transmembrane helices that protrude in the periplasm into a binding domain for interaction with the

185 hus only needs to transport protons from the periplasm into the active site without the requirement t

186 Typhimurium mediates Mg(2+) uptake from the periplasm into the cytoplasm.

187 ovo disulfide bond generation in the E. coli periplasm involves a transient complex consisting of Dsb

188 and Ag(I) ions; this system, located in the periplasm, involves four proteins, CusA, CusB, CusC, and

189 radical in both cytosol and thylakoid lumen/periplasm irrespective of the N-status of growth by regu

190 As the periplasm is an oxidizing environment as compared with t

191 ous in all cases, but in minimal medium, the periplasm is evidently thicker at the cell tips.

192 yond this point and leading to the bacterial periplasm is not known.

193 mbranes through the hydrophilic space of the periplasm is not known.

194 gest that amidase activation via EnvC in the periplasm is regulated by conformational changes in the

195 ys in attachment to the peptidoglycan of the periplasm is unknown.

196 When TMD1 exits the membrane to the periplasm, it liberates TMD2 to participate in the pathw

197 Because the periplasm lacks ATP, the source of energy that drives pa

198 Because the periplasm lacks ATP, vectorial folding of the passenger

199 bacteriocin is required for activity in the periplasm leading to hydrolysis of peptidoglycan.

200 dicating a delivery mechanism by which these periplasm-located yet immunogenic glycoproteins can inte

201 arge number of flagella and the absence of a periplasm make B. subtilis a premier organism for the st

202 some components in the relatively accessible periplasm make it an attractive target for the developme

203 o of 3:6:3 CusA/CusB/CusC to form the CusCBA periplasm membrane transporter.

204 ) was taken up and found associated with the periplasm, membrane or cytoplasm fractions of the cells.

205 Similarly, in the periplasm, MreC controls the spatial orientation of the

206 lymerization of a major pilin protein in the periplasm of a wide range of bacteria and archaea.

207 e been previously shown to be present in the periplasm of aerobically grown cultures of V. cholerae.

208 he lumen of the endoplasmic reticulum or the periplasm of bacteria is mediated by a highly conserved

209 metallic Cu,Zn-SODs are widespread, from the periplasm of bacteria to virtually every organelle in th

210 t CdiA-CT toxins can be transferred into the periplasm of de-energized target bacteria, indicating th

211 In contrast to the cytoplasm, the periplasm of E. coli is maintained in an oxidized state

212 ith slightly substoichiometric zinc from the periplasm of Escherichia coli and is capable of binding

213 several site-directed mutant proteins in the periplasm of Escherichia coli facilitated a detailed in

214 oxification of copper and silver ions in the periplasm of Escherichia coli.

215 o further study folding and targeting in the periplasm of Escherichia coli.

216 rol degradation of misfolded proteins in the periplasm of gram-negative bacteria and is required for

217 ed proteins are known to be delivered to the periplasm of Gram-negative bacteria, the growth medium o

218 ns are found in the cell membrane and in the periplasm of gram-negative bacteria.

219 in complex that spans the inner membrane and periplasm of M. xanthus.

220 cretion exported 3) can be injected into the periplasm of neighboring bacterial competitors by a Type

221 Predatory Bdellovibrio bacteria invade the periplasm of other bacterial prey cells, usually crossin

222 PldB targets the periplasm of prokaryotic cells and exerts an antibacteri

223 viciae 3841 is exported to the periplasm of R. l. bv. viciae and Escherichia coli.

224 two effector proteins, Tse1 and Tse3, to the periplasm of recipient cells.

225 We isolated FlhE from the periplasm of Salmonella and solved its structure to 1.5A

226 ion domain and degrades peptidoglycan in the periplasm of target bacteria.

227 The periplasm of the DeltanlpA DeltadegP strain was determin

228 olecular weight O-antigen accumulates in the periplasm of the mutant.

229 e crowded electron transport proteins in the periplasm of the organism constituted an electron conduc

230 ith the assistance of TolA, a protein in the periplasm of the target cell.

231 fect on the T3S process when exported to the periplasm of the wild-type parent strain.

232 to kill E. coli cells when addressed to the periplasm of these bacteria.

233 Ccps are located in the periplasms of bacteria and the mitochondrial intermembra

234 ly resides outside the cell membrane, in the periplasm or associated with the cell wall.

235 t with OspC mutants that mislocalized to the periplasm or contained C-terminal epitope tags.

236 could attack substrates found either in the periplasm or cytosol of target bacteria.

237 membrane with the lipoprotein domain in the periplasm or outside the cell.

238 Rv0203 transports heme across the bacterial periplasm or scavenges heme from host heme proteins, Mmp

239 lecule is captured by AcrB probably from the periplasm or the periplasm/inner membrane interface, and

240 polysaccharides)--in the form of cell walls, periplasms or gel-like matrices--are ubiquitously presen

241 tion, the tail tube penetrates the host cell periplasm, pausing while it degrades the peptidoglycan l

242 remature amyloidogenesis within the cellular periplasm, preventing early aggregation and cellular tox

243 The accumulation of FeEnt in the periplasm required the binding protein and inner membran

244 CTXPhi transit across the bacterial periplasm requires binding between the minor coat protei

245 ith the N and C termini in the cytoplasm and periplasm, respectively.

246 ant of R. l. bv. viciae exported SodA to the periplasm, ruling out export of SodA as a complex with a

247 a decrease in the oxidizing activity of the periplasm stimulates PhoQ/PhoP and may reveal a new inpu

248 nking of TM2 and the connected region in the periplasm suggest a piston-type shift of TM2 by four res

249 ward the membrane or push it down toward the periplasm, suggesting a possible mechanism for providing

250 C-terminal domain of CpaB is exposed to the periplasm, suggesting that this is the site where CpaA a

251 e of a processed Tsh passenger domain in the periplasm support the possibility that the translocator

252 ires as extensions of the outer membrane and periplasm that include the multiheme cytochromes respons

253 contain an N-terminal module located in the periplasm that includes two polypeptide transport-associ

254 gments fold into a trimeric structure in the periplasm that persists until the termination of passeng

255 ns of the cytochrome-rich outer membrane and periplasm that, when dried, collapse to form filaments w

256 Dsb (disufide bond) system of the bacterial periplasm, the compartment from which the IMS was derive

257 isfolded outer-membrane porins (OMPs) in the periplasm, the E. coli DegS protease cleaves RseA, a tra

258 hat, following delivery of CdiA-CTs into the periplasm, the N-terminal domains bind specific inner-me

259 terminus of bound-form Lpp is located in the periplasm, the precise location of free-form Lpp has nev

260 ding subunits and are bulk components of the periplasm, they represent a Ca(2+) capacitor discharged

261 YbcL requires liberation from the bacterial periplasm, though the mechanism of release is undefined.

262 at establishes an energy gradient across the periplasm, thus driving their sorting by chaperones to t

263 ed to 27 and 24 kDa forms in the cytosol and periplasm/thylakoid lumen.

264 zing entering protons and thus buffering the periplasm to a pH of roughly 6.1 even in gastric juice a

265 F C-terminal signaling domain located in the periplasm to activate the stress response.

266 suggesting a lumen that is fully open to the periplasm to allow for extracellular sugar transport and

267 module TamB to nucleate proper folding from periplasm to cell surface through a cooperative mechanis

268 zed role in transport of inorganic iron from periplasm to cytoplasm, FtrABCD system function did not

269 ) family of serine proteases function in the periplasm to degrade damaged or improperly folded membra

270 it along a filament that extends across the periplasm to directly deliver lipopolysaccharide into th

271 in the transition from rod completion in the periplasm to extracellular hook polymerization.

272 (c20) was isolated directly from S. meliloti periplasm to identify its N-terminal amino acids and the

273 his supports a model in which LpoB spans the periplasm to interact with PBP1B and stimulate PG synthe

274 he cuprous oxidase CueO is secreted into the periplasm to oxidize the more membrane-permeable and tox

275 single pathway for proton delivery from the periplasm to the active site that is shared by all cNORs

276 move LPS from the inner membrane through the periplasm to the cell surface.

277 confirm that LptD/E transports LPS from the periplasm to the external leaflet of the outer membrane.

278 is required for CDI toxin transport from the periplasm to the target-cell cytoplasm.

279 rather requiring them to be converted in the periplasm to their respective sugar acid forms before tr

280 ntrol the flow of protein traffic across the periplasm, uncontrolled activation of this system likely

281 on-type shift of TM2 by four residues to the periplasm upon activation (or fumarate binding).

282 f TM2 by four residues (or 4-6 A) toward the periplasm upon activation is complementary to the peripl

283 uild a peptidoglycan (PG) cell wall in their periplasm using the precursor known as lipid II.

284 Our data indicated that, in the periplasm, various periplasmic and peripheral membrane e

285 transit from the bacterial cytoplasm to the periplasm via an inner-membrane pore complex (TraC and T

286 Export of the R. l. bv. viciae SodA to the periplasm was not limited to the genus Rhizobium, but wa

287 minus in the cytoplasm and C-terminus in the periplasm, was much more particular, requiring an intact

288 ep and HS oligosaccharides imported into the periplasm were degraded by a repertoire of lyases, with

289 TAT secretion signal, were able to reach the periplasm when expressed in the bacterial cytosol.

290 e that OMPs have a prolonged lifetime in the periplasm where an unfolded OMP makes, on average, hundr

291 Tat-dependent manner, delivering Bla to the periplasm where it hydrolyzed beta-lactam antibiotics.

292 YdeI localizes to the periplasm, where it could interact with OmpD.

293 ed) form of PhoP by removing Mg(2+) from the periplasm, where it functions as a repressing signal for

294 ses Hap to mislocalize and accumulate in the periplasm, where it is degraded by HtrA.

295 ve bacteria, peptidoglycan is located in the periplasm, where it is protected from exogenous lytic en

296 that LacZ can be fully translocated into the periplasm, where it is toxic.

297 s of Omp85 family members are located in the periplasm, where they interact with other partner protei

298 ng disulfide bond formation in the bacterial periplasm, which is topologically equivalent to the plas

299 of acid-denatured proteins in the bacterial periplasm, which lacks both ATP and ATP-dependent chaper

300 r expressing these proteins in the bacterial periplasm with the help of signal peptide paves the way