ライフサイエンスコーパス: peritubular capillary

1 antibodies (0 of 8); 27% had neutrophils in peritubular capillaries.

2 epithelium and occasionally, in contact with peritubular capillaries.

3 dr/Vegfr2) is largely restricted to adjacent peritubular capillaries.

4 with a striking reduction in the density of peritubular capillaries.

5 HLA) cause graft injury identified by C4d in peritubular capillaries.

6 in association with immature glomerular and peritubular capillaries.

7 C3d) deposition was diffuse and prominent in peritubular capillaries.

8 microcirculation, especially with regard to peritubular capillaries.

9 optosis in arteries, tubules, glomeruli, and peritubular capillaries.

10 Injury to peritubular capillaries and capillary basement membrane

11 irus infection and were more frequent within peritubular capillaries and glomeruli from antibody-medi

12 scular cells and how these cells detach from peritubular capillaries and migrate to the interstitial

13 Additionally, we found endothelial damage in peritubular capillaries and vasa recta.

14 atient with hemoglobin SC disease who showed peritubular capillary and vasa recta thrombi and capilla

15 had acute graft dysfunction, neutrophils in peritubular capillaries, and a concurrent positive cross

16 IgM, and C5b-9 were scored in the glomeruli, peritubular capillaries, and arterioles.

17 surfaces of endothelial cells in glomerular, peritubular capillary, and arterial renal sites of matur

18 Human kidney peritubular capillaries are particularly susceptible to

19 o cases was the absence of C4d deposition in peritubular capillaries as well as the absence of C1q-bi

20 The aging rats also displayed focal loss of peritubular capillaries (as noted by focally decreased R

21 Severe peritubular capillary basement membrane multilayering (P

22 Peritubular capillary basement membrane multilayering on

23 asured in double-perfused tubules (lumen and peritubular capillaries) by manipulating the applied tra

24 dy (DSA) and histologic evidence of AMR with peritubular capillaries C4d deposition.

25 complement pathway, it was hypothesized that peritubular capillary C4d deposition might distinguish t

26 These results suggest that diffuse peritubular capillary C4d deposition without rejection i

27 teria, including capillaritis, glomerulitis, peritubular capillary C4d deposition, and donor-specific

28 In ABO-incompatible grafts, however, peritubular capillary C4d is often present on protocol b

29 ic associations and clinical implications of peritubular capillary C4d staining from long-term renal

30 nsitivity and specificity by the presence of peritubular capillary C4d staining on renal biopsy and d

31 Peritubular capillary C4d staining was negative in all c

32 Rare peritubular capillary C4d staining was present in 50% of

33 y-one patients (group A) had strong, diffuse peritubular capillary C4d staining without histologic ev

34 degree of microcirculation inflammation and peritubular capillary C4d staining.

35 tients (group B) had negative or weak, focal peritubular capillary C4d staining.

36 onents correlated with the g score, DSA, and peritubular capillary C4d+.

37 r endothelium, resulting in the formation of peritubular capillary C4d.

38 ury, with a relative loss of staining of the peritubular capillaries compared with young rats.

39 The loss of peritubular capillary density and caliber at week 8 clos

40 h mice to visualize, analyze, and quantitate peritubular capillary dynamics after AKI.

41 kidney, TNFR1 is expressed in glomerular and peritubular capillary EC, and some tubular cells, and co

42 ely associated with CD31- and Tie-2-positive peritubular capillary endothelia, and some of the alpha

43 was also associated with more glomerular and peritubular capillary endothelial cell loss in associati

44 us vehicle, P < 0.05), a twofold increase in peritubular capillary endothelial cell proliferation (1.

45 nal unit, formed by resident macrophages and peritubular capillary endothelial cells, which monitors

46 Damage to tubular epithelium and peritubular capillary endothelium also was seen.

47 herefrom perturb normal interactions between peritubular capillary endothelium and pericyte-like fibr

48 Additionally, HIFD significantly reduced peritubular capillary erythrocyte congestion and improve

49 ohistochemistry and evaluated on arterioles, peritubular capillaries, glomeruli, and tubular basement

50 Although C4d deposition in peritubular capillaries has been identified as a strong

51 i1(+) kidney pericytes in the maintenance of peritubular capillary health, and the consequences of pe

52 d deposited prominently and diffusely in the peritubular capillaries in all AHR biopsies (16 of 16).

53 y-implicated in the progressive attrition of peritubular capillaries in areas of tubular atrophy and

54 ition and thrombosis in renal glomerular and peritubular capillaries in association with a fall in he

55 Endothelial cells of the peritubular capillaries in grafts with ABMR expressed fa

56 We explored the integrity of peritubular capillaries in relation to expression of vas

57 s are also related to the presence of C4d in peritubular capillaries in TG biopsies.

58 of the basement membranes (glomerular and/or peritubular capillaries) in milder forms of injury.

59 ated rejection manifests with glomerular and peritubular capillary inflammation and transplant glomer

60 ial, mononuclear cell infiltrates; prominent peritubular capillary inflammatory cell margination; pat

61 be the consequence of ischemia secondary to peritubular capillary injury and altered eNOS expression

62 C4d deposition in peritubular capillaries is a specific marker for the pre

63 Ang-1 therapies attenuate peritubular capillary loss in adult models of tubulointe

64 nti-angiogenic effects leading to aggravated peritubular capillary loss.

65 jury as evidenced by reduced C4d staining in peritubular capillaries, microcirculation inflammation,

66 Glomerular CD68+ cells correlated with peritubular capillary multilamellation, and similarly, t

67 loss, the optimal cutoff for the fraction of peritubular capillaries needed to establish a positive s

68 was associated with a higher density of the peritubular capillary network in the corticomedullary ju

69 Integrity of the renal peritubular capillary network is an important limiting f

70 alk by Vegfa is essential for maintenance of peritubular capillary networks in kidney.

71 e AKI, we measured a 40%+/-7.4% reduction in peritubular capillary number (P<0.05) and a 36%+/-4% dec

72 genetically labeled endothelia, we compared peritubular capillary number and size after moderate AKI

73 Diffuse C4d deposition was detected in the peritubular capillaries of 6 of 48 (13%) biopsies.

74 ecificity the endothelium of the fenestrated peritubular capillaries of the kidney and those of the i

75 In ACR, no more than trace C4d was found in peritubular capillaries (P < 0.0001 versus AHR), and no

76 etection of the C4d complement product along peritubular capillaries (PC) may indicate humoral reject

77 organ level, trametinib completely restored peritubular capillary perfusion in the kidney.

78 e increased pericytes around kidney cortical peritubular capillaries, perhaps an indirect consequence

79 calized E-selectin to the endothelium of the peritubular capillary plexus.

80 d by determining whether C4d is deposited in peritubular capillaries (PTC) and whether it correlates

81 r of layers of basement membrane (BM) around peritubular capillaries (PTC) can be used in a cohort of

82 C4d deposition in peritubular capillaries (PTC) of renal allografts has be

83 graft function (DGF) and to an early loss of peritubular capillaries (PTC).

84 odies (DSA) and complement C4d deposition in peritubular capillaries (PTC).

85 inical and molecular significance of minimal peritubular capillary (PTC) and isolated glomerular C4d+

86 whether, on electron microscopy examination, peritubular capillary (PTC) basement membrane multilayer

87 for allograft dysfunction, were assessed for peritubular capillary (PTC) C4d and CD55 expression.

88 ediated rejection, which is characterized by peritubular capillary (PTC) deposition of C4d.

89 Deposition of C4d in peritubular capillaries (PTCs) has been shown to be a se

90 nic kidney diseases, leads to rarefaction of peritubular capillaries (PTCs), promoting secondary isch

91 vehicle, P < 0.01), a threefold decrease in peritubular capillary rarefaction (P < 0.01), and a twof

92 Peritubular capillary rarefaction is hypothesized to con

93 We detected glomerular and peritubular capillary rarefaction, macrophage infiltrati

94 igger transient tubular injury and permanent peritubular capillary rarefaction.

95 operfusion of L-arginine (10[-3] M) into the peritubular capillaries reduced the maximum TGF response

96 The percentage of peritubular capillaries staining positively for C4d was

97 ata show that in long-term renal allografts, peritubular capillary staining for C4d occurs in approxi

98 ion, Nec-1 prevented RCM-induced dilation of peritubular capillaries, suggesting a novel role unrelat

99 of rejection had widespread C4d deposits in peritubular capillaries, suggesting a pathogenic role of

100 ted with preservation or accelerated loss of peritubular capillaries, suggesting no significant pro-a

101 anism for this epidemiologic link is loss of peritubular capillaries triggering chronic hypoxia.

102 howed gp-Fy in the endothelium of glomeruli, peritubular capillaries, vasa recta, and the principal c

103 C4d in peritubular capillary walls distinguishes AHR from ACR,

104 Fascin1 expression in peritubular capillaries was also induced in a rat model

105 The presence of C4d in peritubular capillaries was an independent risk factor f

106 ndothelial cell adhesion molecule-expressing peritubular capillaries was preceded by marked decreases

107 e higher in NRs, whereas Banff-C4d scores of peritubular capillaries were increased in the Rs.

108 Glomerular and peritubular capillaries were increased with endothelial

109 sensitive AR, and widespread C4d deposits in peritubular capillaries were present in 18 of these 19 (

110 ficiency causes dysmorphogenesis of cortical peritubular capillaries, with adjacent cells expressing

111 scopy revealed dilation of renal tubules and peritubular capillaries within 20 minutes of RCM applica